77737-5
Mycobacterium abscessus complex clarithromycin resistance erm(41) gene panel by Molecular genetics method
Active
77735-9 Mycobacterium abscessus complex clarithromycin resistance erm(41) truncated gene [Presence] by Molecular method
Term Description
Detection of truncated gene variants of the erm(41) gene unique to Mycobacterium abscessus complex, particularly M. abscessus subsp. massiliense, from clinical isolates by real-time PCR.
Source: Regenstrief LOINC
Part Descriptions
LP190748-6 Mycobacterium abscessus complex clarithromycin resistance erm(41) truncated gene
The M. abscessus complex consists of three subspecies (M. abscessus subsp. Abscessus, M. abscessus subsp. Massiliense, M. abscessus subsp. Bolletii). PMID: 22403419 They are known to cause respiratory disease in cystic fibrosis and elderly patients as well as skin and soft tissue infections. PMID: 25106861 M. abscessus infections are often difficult to treat as many strains are resistant to most of the common antibiotics. Their resistance to clarithromycin can be determined based on expression of the inducible ribomethylase gene, erm(41). The presence of a full length functional erm(41)gene, which is specific for M. abscessus, confers inducible resistance to clarithromycin while the non-functional truncated erm(41) gene exhibits higher drug susceptibility. PMID: 22290346 Real-time PCR methods are performed to detect the presence of the full or truncated erm(41) gene and determine proper treatment for patients.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Mycobacterium abscessus complex clarithromycin resistance erm(41) truncated gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- M absces erm(41) trunc Islt/Spm Ql
- Display Name
- M. abscessus complex clarithromycin resistance erm(41) truncated gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Mycobacterium abscessus complex clarithromycin resistance erm(41) truncated gene
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.65
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses from Component because the contents represent a gene name, not an acronym; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Both
Example Answer List LL3596-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 | ||
| Inconclusive Copyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 77737-5 | Mycobacterium abscessus complex clarithromycin resistance erm(41) gene panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Mycobacterium-abscessus-Komplex Clarithromycin-Resistenz verkürztes erm(41)-Gen: |
| es-ES | Spanish (Spain) | Mycobacterium abscessus complex resistente a claritromicina (erm(41)) gen truncado: |
| es-MX | Spanish (Mexico) | Mycobacterium abscessus complex resistencia a claritromicina erm (41) gen truncado: |
| fr-FR | French (France) | Mycobacterium complexe abscessus résistance à la clarithromycine erm(41) gène tronqué: |
| it-IT | Italian (Italy) | Complesso Mycobacterium abscessus claritromicina resistente, gene troncato (erm(41)): Synonyms: Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | Mycobacterium abscessus complex clarithromycine-resistent (erm(41)) afgekapt gen: Synonyms: isolaat/specimen molgen |
| zh-CN | Chinese (China) | 脓肿分枝杆菌复合体克拉霉素耐药 erm(41) 截短基因: Synonyms: AFB 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
77734-2 Mycobacterium abscessus complex clarithromycin resistance erm(41) full length gene [Presence] by Molecular method
Term Description
Detection of the full length gene variants of the erm(41) gene unique to Mycobacterium abscessus complex from clinical isolates by real-time PCR.
Source: Regenstrief LOINC
Part Descriptions
LP190747-8 Mycobacterium abscessus complex clarithromycin resistance erm(41) full length gene
The M. abscessus complex consists of three subspecies (M. abscessus subsp. Abscessus, M. abscessus subsp. Massiliense, M. abscessus subsp. Bolletii). PMID: 22403419 They are known to cause respiratory disease in cystic fibrosis and elderly patients as well as skin and soft tissue infections. PMID: 25106861 M. abscessus infections are often difficult to treat as many strains are resistant to most of the common antibiotics. Their resistance to clarithromycin can be determined based on expression of the inducible ribomethylase gene, erm(41). The presence of a full length functional erm(41)gene, which is specific for M. abscessus, confers inducible resistance to clarithromycin while the non-functional truncated erm(41) gene exhibits higher drug susceptibility. PMID: 22290346 Real-time PCR methods are performed to detect the presence of the full or truncated erm(41) gene and determine proper treatment for patients.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Mycobacterium abscessus complex clarithromycin resistance erm(41) full length gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- M abscess erm(41) full Islt/Spm Ql
- Display Name
- M. abscessus complex clarithromycin resistance erm(41) full length gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Mycobacterium abscessus complex clarithromycin resistance erm(41) full length gene
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.65
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses from Component because the contents represent a gene name, not an acronym.; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Both
Example Answer List LL3596-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 | ||
| Inconclusive Copyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 77737-5 | Mycobacterium abscessus complex clarithromycin resistance erm(41) gene panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Mycobacterium-abscessus-Komplex Clarithromycin-Resistenz erm(41)-Gen in voller Länge: |
| es-ES | Spanish (Spain) | Mycobacterium abscessus complex resistente a claritromicina (erm(41)) gen completo: |
| es-MX | Spanish (Mexico) | Mycobacterium abscessus complex resistencia a claritromicina erm (41) gen de longitud completa: |
| fr-FR | French (France) | Mycobacterium complexe abscessus résistance à la clarithromycine erm(41) gène complet: |
| it-IT | Italian (Italy) | Complesso Mycobacterium abscessus claritromicina resistente, gene full lenght (erm(41)): Synonyms: Complesso Mycobacterium abscessus claritromicina r Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | Mycobacterium abscessus complex clarithromycine-resistent (erm(41)) volle lengte gen: Synonyms: isolaat/specimen molgen |
| zh-CN | Chinese (China) | 脓肿分枝杆菌复合体克拉霉素耐药 erm(41) 全长基因: Synonyms: AFB 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
77736-7 Mycobacterium abscessus complex clarithromycin resistance erm(41) gene [Interpretation] by Molecular method
Term Description
The interpretation for RT-PCR detection of full length and truncated gene variants of the erm(41) gene unique to Mycobacterium abscessus complex (M. abscessus, M. massiliense, and M. bolletii) from clinical isolates. The presence of a full length functional erm(41)gene confers inducible resistance to clarithromycin while the non-functional truncated erm(41) gene exhibits higher drug susceptibility. PMID: 22290346
Source: Regenstrief LOINC
Part Descriptions
LP190749-4 Mycobacterium abscessus complex clarithromycin resistance erm(41) gene
The M. abscessus complex consists of three subspecies (M. abscessus subsp. Abscessus, M. abscessus subsp. Massiliense, M. abscessus subsp. Bolletii). PMID: 22403419 They are known to cause respiratory disease in cystic fibrosis and elderly patients as well as skin and soft tissue infections. PMID: 25106861 M. abscessus infections are often difficult to treat as many strains are resistant to most of the common antibiotics. Their resistance to clarithromycin can be determined based on expression of the inducible ribomethylase gene, erm(41). The presence of a full length functional erm(41)gene, which is specific for M. abscessus, confers inducible resistance to clarithromycin while the non-functional truncated erm(41) gene exhibits higher drug susceptibility. PMID: 22290346 Real-time PCR methods are performed to detect the presence of the full or truncated erm(41) gene and determine proper treatment for patients.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Mycobacterium abscessus complex clarithromycin resistance erm(41) gene
- Property
- Imp
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Nom
- Method
- Molgen
Additional Names
- Short Name
- M abscessus erm(41) Islt/Spm-Imp
- Display Name
- M. abscessus complex clarithromycin resistance erm(41) gene Molgen (Islt/Spec) [Interp]
- Consumer Name Alpha Get Info
- Mycobacterium abscessus complex clarithromycin resistance erm(41) gene
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.65
- Change Reason
- Removed parentheses around "erm(41)" in Component based on our current LOINC model.; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Both
Example Answer List LL3595-7
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Not detected | LA11883-8 | ||
| Full length erm(41) present, suggests inducible clarithromycin resistance. Culture is required to confirm these results. | LA23797-6 | ||
| Truncated erm(41) present, suggests clarthromycin susceptibility. Culture is required to confirm these results. | LA23798-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 77737-5 | Mycobacterium abscessus complex clarithromycin resistance erm(41) gene panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Mycobacterium-abscessus-Komplex Clarithromycin-Resistenz erm(41)-Gen: |
| es-MX | Spanish (Mexico) | Gen erm (41) de resistencia a claritromicina del complejo Mycobacterium abscessus: |
| es-ES | Spanish (Spain) | Mycobacterium abscessus complex resistente a claritromicina (erm(41)) gen: |
| fr-FR | French (France) | Mycobacterium complexe abscessus résistance à la clarithromycine erm(41) gène: |
| it-IT | Italian (Italy) | Complesso Mycobacterium abscessus claritromicina resistente, gene (erm(41)): Synonyms: Genetica molecolare Impressione/interpretazione di studio Isolato o Campione Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | Mycobacterium abscessus complex clarithromycine-resistent (erm(41)) gen: Synonyms: isolaat/specimen molgen |
| zh-CN | Chinese (China) | 脓肿分枝杆菌复合体克拉霉素耐药 erm(41) 基因: Synonyms: AFB 供检查用的材料; |