77770-6
HYDROmorphone cutoff [Mass/volume] in Saliva (oral fluid) for Confirmatory method
Active
Part Descriptions
LP16162-7 HYDROmorphone
Hydromorphone is a drug used to relieve moderate to severe pain. It is known by the trade name Dilaudid®. An extended-release version called Palladone® SR was available for a short time in the United States before being voluntarily withdrawn from the market after an FDA advisory released in July 2005. Hydromorphone belongs to a category of drugs known as opioid agonists. It is commonly given to patients who have recently undergone surgery or who have suffered serious injury. Hydromorphone is often sought after by opiate drug abusers as it is one of the most potent of all prescription narcotics, when taken parenterally.
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Source: Wikipedia, Hydromorphone (Wikipedia)
LP16162-7 HYDROmorphone
Hydromorphone is an opioid and part of a large class of medications used to treat acute and chronic pain and manage opioid abuse and dependence. It is metabolized in the liver to hydromorphone-3-glucuronide (H3G, ~40%), dihydroisomorphine (~ 1%), dihydromorphine (~.1%) as well as trace amounts of hydromorphone-3-sulfate, norhydromorphone, and nordihydroisomorphone. PMID: 15504625 Hydromorphone and its metabolites are excreted from the kidney and can be detected in urine to monitor compliance or identify illicit opioid drug use.
Source: Regenstrief LOINC
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HYDROmorphone cutoff
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- HYDROmorphone CtO Sal Cfm-mCnc
- Display Name
- HYDROmorphone cutoff Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- HYDROmorphone cutoff, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.52
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Hidromorfona Punto de corte: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Corte de HIDROmorfona: |
et-EE | Estonian (Estonia) | Hüdromorfoon otsustuspiir: Synonyms: Juhuslik Kvantitatiivne Sülg |
fr-CA | French (Canada) | Hydromorphone Seuil décisionnel: Synonyms: #REF! |
fr-FR | French (France) | Hydromorphone cut off: |
fr-BE | French (Belgium) | Hydromorphone Seuil décisionnel: Synonyms: Seuil décisionnel |
it-IT | Italian (Italy) | Idromorfone, cutoff: Synonyms: Concentrazione di Massa Cut-off Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | hydromorfon afkapwaarde: |
pl-PL | Polish (Poland) | HYDROmorfon wartość odcięcia: |
ru-RU | Russian (Russian Federation) | Гидроморфон порог: Synonyms: Количественный Массовая концентрация Точка во времени; |
tr-TR | Turkish (Turkey) | Hidromorfon kestirim: Synonyms: Teyid |
zh-CN | Chinese (China) | 二氢吗啡酮 截止点: Synonyms: 可用数量表示的; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
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