Version 2.78

Term Description

This term was created for, but is not limited in use to, the CEP 3 SpectrumOrange DNA Probe Kit, which detects sequences in the centromere region of chromosome 3 in order to identify chromosome 3 trisomy. This test is used as an adjunct to routine diagnostic cytogenetic testing involving chromosome 3.
Source: Regenstrief LOINC

Part Description

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
Chromosome 3 copy number/nucleus
Property
EntNum
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
Chr 3 copy num/nucleus EntNum Bld/T FISH
Display Name
Chr 3 copy number/nucleus FISH (Bld/Tiss) [Entitic number]
Consumer Name Alpha Get Info
Chromosome 3 copy number/nucleus, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRISOMY
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.66
Change Reason
Updated "signals" in Component to "copy number" to align with current nomenclature and similar terms
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) señales de marcaje cromosoma 3/núcleo:Número entítico:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Número de copias / núcleo del cromosoma 3:Número entitic:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) Chromosome 3 nombre de copie/noyaux:Nombre/entité:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT Italian (Italy) Cromosoma 3 segnali/nucleo:EntNum:Pt:Sangue/Tess:Qn:FISH
Synonyms: Ibridazione in situ fluorescente (FISH) Numero entitico Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Trisomia cromosoma genetica
nl-NL Dutch (Netherlands) aantal centromeren van chromosoom 3/kern:aantal/eenheid:moment:bloed of weefsel:kwantitatief:FISH
Synonyms: CEP3 nucleus
pl-PL Polish (Poland) Liczba kopii chromosomu 3/jądro:liczba zawarta w:punkt w czasie:krew lub tkanka:ilościowy:fluorescencyjna hybrydyzacja in situ (FISH)
tr-TR Turkish (Turkey) Kromozom 3 sinyalleri/çekirdek:EntSay:Zmlı:Kan/Dk:Kant:FISH
zh-CN Chinese (China) 染色体 3 拷贝数/核:实体数量:时间点:全血/组织:定量型:FISH
Synonyms: Ⅲ Fluorescent in situ hybridization;荧光原位杂交 III 三 三体型 三体细胞 三染色体性 三染色体细胞 个数;数目 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子病理学试验类.三体性（三体型） 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实体计数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体 3 （3号染色体）拷贝（副本）数（数量、计数）;3号染色体拷贝数;3 号染色体信号;染色体 3 信号 染色体二体型+染色体三体型 细胞核 血;血液

Example Units

Unit Source
{#} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78238-3