Version 2.78

3693-9 Imipramine [Mass/volume] in Serum or Plasma --trough

Part Descriptions

LP16166-8   Imipramine
Imipramine (sold as Antideprin ®, Deprenil, Deprimin, Deprinol, Depsonil, Dynaprin, Eupramin, Imipramil, Irmin, Janimine ®, Melipramin, Surplix, Tofranil ®) is an antidepressant medication, a tricyclic antidepressant of the dibenzazepine group, mainly used in the treatment of clinical depression and enuresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Imipramine (Wikipedia)

LP16166-8   Imipramine
The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group. Source: National Library of Medicine, MeSH 2006

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
Imipramine^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Imipramine Trough SerPl-mCnc
Display Name
Imipramine trough [Mass/Vol]
Consumer Name Alpha Get Info
Imipramine trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
78365-4 Imipramine trough, Imipramine+desimipramine trough and Desipramine panell - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Imipramina ^ canal:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Imipramina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-AR Spanish (Argentina) imipramina^concentración mínima [valle]:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
et-EE Estonian (Estonia) Imipramiin^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-BE French (Belgium) Imipramine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
fr-FR French (France) Imipramine taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA French (Canada) Imipramine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Imipramina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
ko-KR Korean (Korea, Republic Of) 이미프라민^최저 약물사용 수준 시간:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) imipramine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Imipramina^basal:MCnc:Pt:Sor/Plas:Qn:
Synonyms: Imipra; Tofranil; Pre; Predose; Pre-dose; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Имипрамин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) İmipramin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 丙咪嗪^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: C19H24N2 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ng/mL Example UCUM Units

78362-1 Imipramine+Desipramine [Mass/volume] in Serum or Plasma --trough

Term Description

Sample is drawn at the expected trough (baseline) level of the parent drug (Imipramine).
Source: Regenstrief LOINC

Part Descriptions

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
Imipramine+Desipramine^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Imipramine+Desipr Trough SerPl-mCnc
Display Name
Imipramine+Desipramine trough [Mass/Vol]
Consumer Name Alpha Get Info
Imipramine+Desipramine trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
78365-4 Imipramine trough, Imipramine+desimipramine trough and Desipramine panell - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Imipramina + Desipramina ^ a través:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Imipramina+desipramina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Imipramiin + desipramiin^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Imipramine+désipramine cut off:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA French (Canada) Imipramine+Désipramine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BE French (Belgium) Imipramine+Désipramine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Imipramina+Desipramina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) imipramine + desipramine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
ru-RU Russian (Russian Federation) Имипрамин+Дезипрамин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) İmipramin+Desipramin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 丙咪嗪+去甲丙咪嗪^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: C18H22N2;丙咪嗪代谢产物;去甲基丙咪嗪;去郁敏;地昔帕明 C19H24N2 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 丙咪嗪+去甲丙咪嗪(地昔帕明、脱甲丙咪嗪、地西帕明) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ug/L Example UCUM Units

3531-1 Desipramine [Mass/volume] in Serum or Plasma

Part Descriptions

LP16103-1   Desipramine
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin ® and Pertofrane ®. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. Along with other tricyclics, desipramine has found use in treating neuropathic pain. The mechanism of action seems to involve the activation, through norepinephrine reuptake inhibition, of descending pathways in the spinal cord that block pain signals from ascending to the brain. Desipramine is one of the most potent and selective medications in this respect. Some evidence suggests that desipramine may help with ADD. See also:antidepressant tricyclic antidepressant External links:Desipramine - medicinenet.comDesipramine - medlineplus. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Desipramine (Wikipedia)

LP16103-1   Desipramine
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Desipramine
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Desipramine SerPl-mCnc
Display Name
Desipramine [Mass/Vol]
Consumer Name Alpha Get Info
Desipramine, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6545

Member of these Panels

LOINC Long Common Name
43123-9 Imipramine and Desipramine panel - Serum or Plasma
78365-4 Imipramine trough, Imipramine+desimipramine trough and Desipramine panell - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG44012-9 Desipramine|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Desimipramin
de-DE German (Germany) Desipramin:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
es-AR Spanish (Argentina) desipramina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-MX Spanish (Mexico) Desipramina:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Desipramina:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Desipramiin:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Désipramine:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA French (Canada) Désipramine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BE French (Belgium) Désipramine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Desipramina:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 데시프라민:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) desipramine:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Desipramina:MCnc:Pt:Sor/Plas:Qn:
Synonyms: Imipramine metAcolite; Desipra; Desi; Desip; Norpramin; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Дезипрамин:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Desipramin:KütlKons:Zmlı:Ser/Plaz:Kant:
uk-UA Ukrainian (Ukraine) Дезипрамін:Масова Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:
Synonyms: Desi; Desip; Desipra; Desmethylimipramine; DRUG/TOXICOLOGY; Drugs; Imipramine metabolite; Level; Mass concentration; Norpramin; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR
zh-CN Chinese (China) 去甲丙咪嗪:质量浓度:时间点:血清/血浆:定量型:
Synonyms: C18H22N2;丙咪嗪代谢产物;去甲基丙咪嗪;去郁敏;地昔帕明 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ng/mL Example UCUM Units
ng/mL REGENSTRIEF