78434-8
carBAMazepine free and total trough and 10,11-Epoxide panel - Serum or Plasma
Active
Term Description
Trough levels of carbamazepine free and total along with levels for 10,11-epoxide are measured for therapeutic anticonvulsant monitoring.
Part Description
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
| LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
|---|---|---|---|---|
| 78434-8 | carBAMazepine free and total trough and 10,11-Epoxide panel - Serum or Plasma | |||
| Indent74974-7 | carBAMazepine free [Mass/volume] in Serum or Plasma --trough | mg/L | ||
| Indent74973-9 | carBAMazepine [Mass/volume] in Serum or Plasma --trough | mg/L | ||
| Indent9415-1 | Carbamazepine 10,11-Epoxide [Mass/volume] in Serum or Plasma | ug/mL |
LOINC Names Get Info
- Fully-Specified Name
- carBAMazepine free & total trough & 10,11-Epoxide panel:
-: Pt: Ser/Plas: Qn: - Long Common Name
- carBAMazepine free and total trough and 10,11-Epoxide panel - Serum or Plasma
- Short Name
- Carbmzpn Trgh + Metab Pnl SerPl
- Display Name
- carBAMazepine free and total trough and 10,11-Epoxide panel
- Consumer Name Alpha Get Info
- Free and Total Trough and 10,11-Epoxide carBAMazepine panel, Blood
Part Model Get Info
- Component
- carBAMazepine free & total trough & 10,11-Epoxide panel
LP199557-2
- Analyte
- carBAMazepine free & total trough & 10,11-Epoxide panel
LP199557-2
- Component Numerator
- carBAMazepine free & total trough & 10,11-Epoxide panel
LP199557-2
- Component Numerator Core
- carBAMazepine free & total trough & 10,11-Epoxide panel
LP199557-2
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- -
LP6769-6
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser/Plas
LP7576-4
- System Core
- Ser/Plas
LP7576-4
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- PANEL.DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54 (MIN)
- Order vs. Observation
- Order
- Panel Type
- Panel
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Karbamazepin volný a karbamazepin údolní koncentrace a 10,11-epoxid panel: |
| el-GR | Greek (Greece) | Πίνακας ελεύθερης & ελαχίστων επιπέδων ολικής καρβαμαζεπίνης & 10,11-εποξειδίου: Synonyms: DRUG/TOX PANEL.DRUG/TOX Pt Qn Καρβαμαζεπίνη Καρβαμαζεπίνη.ελεύθερη Ορός Ορός/Πλάσμα Πίνακας ελεύθερης & |
| es-ES | Spanish (Spain) | Panel de carbamazepina libre y total valle y 10,11-Epoxido: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | libre de carBAMazepina y canal total y panel de 10,11-epóxido: |
| fr-FR | French (France) | Carbamazépine libre et totale taux résiduel et époxycarbamazépine panel: |
| it-IT | Italian (Italy) | Carbamazepina libera & valore minimo totale & 10,11-Epossido, panel: Synonyms: Carbamazepina libera Livelli farmacologici e tossicologia Panel Carbamazepina libera & |
| pl-PL | Polish (Poland) | Karbamazepina wolna & całkowita stężenie minimalne & 10,11-Epoksyd panel: Synonyms: Panel stężenie minimalne wolnej i całkowitej karbamazepiny i 10,11-Epoksydu Wolna Karbamazepina |
| tr-TR | Turkish (Turkey) | Karbamazepin serbest ve total en düşük ve 10,11-Epoksid panel: |
| zh-CN | Chinese (China) | 游离型与总卡马西平波谷与 10,11-环氧化物组套: Synonyms: C15H12N2O; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=78434-8 - Questionnaire definition
- https:
//fhir.loinc.org/Questionnaire/?url=http: //loinc.org/q/78434-8
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://