79165-7
OXcarbazepine trough and 10-hydroxycarbazepine panel - Serum or Plasma
Active
72659-6 OXcarbazepine [Mass/volume] in Serum or Plasma --trough
Part Descriptions
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
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Source: Wikipedia, Trough levels for therapeutic drug monitoring
LP20805-5 OXcarbazepine
Oxcarbazepine is an anticonvulsant used to treat epilepsy and sometimes bipolar disorder. The metabolite of oxcarbazepine, 10-Hydroxycarbazepine, inhibits the repetitive neuronal firing and propagation of synaptic impulses associated with seizures by blocking voltage-gated sodium channels in the brain. [PubChem:34312]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- OXcarbazepine^trough
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- OXcarbazepine Trough SerPl-mCnc
- Display Name
- OXcarbazepine trough [Mass/Vol]
- Consumer Name Alpha Get Info
- OXcarbazepine trough, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.42
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
79165-7 | OXcarbazepine trough and 10-hydroxycarbazepine panel - Serum or Plasma |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50291-0 | Oxcarbazepine^trough| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-MX | Spanish (Mexico) | OXcarbazepina ^ a través: |
es-ES | Spanish (Spain) | Oxcarbazepina^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Okskarbatsepiin^baas: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-BE | French (Belgium) | Oxcarbazépine^Creux: Synonyms: Minimum, nadir |
fr-FR | French (France) | Oxcarbazépine taux résiduel: |
fr-CA | French (Canada) | Oxcarbazépine^Creux: Synonyms: #REF! |
it-IT | Italian (Italy) | Oxcarbazepina^valore minimo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
nl-NL | Dutch (Netherlands) | oxcarbazepine^dalspiegel: |
pt-BR | Portuguese (Brazil) | Oxcarbazepina^basal: |
ru-RU | Russian (Russian Federation) | Окскарбазепин^остаточная концентрация: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Okzarbazepin^en düşük: Synonyms: çukur düzey |
zh-CN | Chinese (China) | 奥卡西平^波谷: Synonyms: 一剂药物的初始剂量; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
31019-3 10-Hydroxycarbazepine [Mass/volume] in Serum or Plasma
Part Descriptions
LP28716-6 10-Hydroxycarbazepine
Oxcarbazepine is used as an adjunctive therapy for treatment of partial seizures in patients with epilepsy. It works by lowering the level of abnormal electrical activity in the brain. Oxcarbazepine is also used to treat bipolar disorders. 10-monohydroxy derivative (MHD) is the primary active metabolite of oxcarbazepine. MHD is used to monitor oxcarbazepine therapy because it reaches peak plasma concentration in 4-6 hours and does not undergo significant metabolism, compared to oxcarbazepine, which has a half-life of 1-2 hours. PMID: 16599412.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 10-Hydroxycarbazepine
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 10OH-Carbazepine SerPl-mCnc
- Display Name
- 10-Hydroxycarbazepine [Mass/Vol]
- Consumer Name Alpha Get Info
- 10-Hydroxycarbazepine, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.04
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2425
Member of these Panels
LOINC | Long Common Name |
---|---|
79165-7 | OXcarbazepine trough and 10-hydroxycarbazepine panel - Serum or Plasma |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG12240-4 | 10-Hydroxycarbazepine| |
LG41870-3 | 10-Hydroxycarbazepine| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: 10-OH-Carbazepin |
es-AR | Spanish (Argentina) | 10-hidroxicarbazepina: |
es-MX | Spanish (Mexico) | 10-hidroxicarbazepina: |
es-ES | Spanish (Spain) | 10-hidroxicarbazepina: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | 10-hüdroksükarbasepiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-FR | French (France) | 10-hydroxycarbamazépine: |
fr-CA | French (Canada) | 10-hydroxycarbazépine: |
fr-BE | French (Belgium) | 10-hydroxycarbazépine: |
it-IT | Italian (Italy) | 10-idrossi carbazepina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 10-하이드로옥스카바제핀: |
nl-NL | Dutch (Netherlands) | 10-hydroxycarbazepine: |
pt-BR | Portuguese (Brazil) | 10-Hidroxicarbazepina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | 10-гидроксикарбазепин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | 10-Hidroksikarbazepin: |
zh-CN | Chinese (China) | 10-羟基卡马西平: Synonyms: 10,11-二羟基-10-羟基卡马西平; |
Example Units
Unit | Source |
---|---|
ug/mL | Example UCUM Units |
mcg/mL | REGENSTRIEF |