Version 2.78

72659-6 OXcarbazepine [Mass/volume] in Serum or Plasma --trough

Part Descriptions

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LP20805-5   OXcarbazepine
Oxcarbazepine is an anticonvulsant used to treat epilepsy and sometimes bipolar disorder. The metabolite of oxcarbazepine, 10-Hydroxycarbazepine, inhibits the repetitive neuronal firing and propagation of synaptic impulses associated with seizures by blocking voltage-gated sodium channels in the brain. [PubChem:34312] Source: Regenstrief LOINC

Fully-Specified Name

Component
OXcarbazepine^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
OXcarbazepine Trough SerPl-mCnc
Display Name
OXcarbazepine trough [Mass/Vol]
Consumer Name Alpha Get Info
OXcarbazepine trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79165-7 OXcarbazepine trough and 10-hydroxycarbazepine panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG50291-0 Oxcarbazepine^trough|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) OXcarbazepina ^ a través:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Oxcarbazepina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Okskarbatsepiin^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-BE French (Belgium) Oxcarbazépine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
fr-FR French (France) Oxcarbazépine taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA French (Canada) Oxcarbazépine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: #REF!
it-IT Italian (Italy) Oxcarbazepina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) oxcarbazepine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Oxcarbazepina^basal::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Окскарбазепин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Okzarbazepin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 奥卡西平^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 卡巴西亚肟 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
mg/L Example UCUM Units

31019-3 10-Hydroxycarbazepine [Mass/volume] in Serum or Plasma

Part Descriptions

LP28716-6   10-Hydroxycarbazepine
Oxcarbazepine is used as an adjunctive therapy for treatment of partial seizures in patients with epilepsy. It works by lowering the level of abnormal electrical activity in the brain. Oxcarbazepine is also used to treat bipolar disorders. 10-monohydroxy derivative (MHD) is the primary active metabolite of oxcarbazepine. MHD is used to monitor oxcarbazepine therapy because it reaches peak plasma concentration in 4-6 hours and does not undergo significant metabolism, compared to oxcarbazepine, which has a half-life of 1-2 hours. PMID: 16599412. Source: Regenstrief LOINC

Fully-Specified Name

Component
10-Hydroxycarbazepine
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
10OH-Carbazepine SerPl-mCnc
Display Name
10-Hydroxycarbazepine [Mass/Vol]
Consumer Name Alpha Get Info
10-Hydroxycarbazepine, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.04
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
2425

Member of these Panels

LOINC Long Common Name
79165-7 OXcarbazepine trough and 10-hydroxycarbazepine panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG12240-4 10-Hydroxycarbazepine|MCnc|Pt|ANYBldSerPl
LG41870-3 10-Hydroxycarbazepine|Pt|Ser/Plas|254.28 g/mole

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: 10-OH-Carbazepin
es-AR Spanish (Argentina) 10-hidroxicarbazepina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-MX Spanish (Mexico) 10-hidroxicarbazepina:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) 10-hidroxicarbazepina:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) 10-hüdroksükarbasepiin:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) 10-hydroxycarbamazépine:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA French (Canada) 10-hydroxycarbazépine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BE French (Belgium) 10-hydroxycarbazépine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) 10-idrossi carbazepina:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 10-하이드로옥스카바제핀:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) 10-hydroxycarbazepine:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) 10-Hidroxicarbazepina:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; 10OH-Carbazepine; Oxcarbazepine metAcolite; 10-OH-carbazepine; 10,11-dihydro-10-hydroxycarbamazepine; 10-hydroxycarbamazepine; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) 10-гидроксикарбазепин:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) 10-Hidroksikarbazepin:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 10-羟基卡马西平:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 10,11-二羟基-10-羟基卡马西平;10-OH-卡马西平;奥卡西平代谢产物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ug/mL Example UCUM Units
mcg/mL REGENSTRIEF