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Part Descriptions

LP200476-2   inv(2)(p21;p23)(EML4,ALK)
The inversion on chromosome 2 resulting in the fusion of genes EM4L [HGNC ID: 1316] and ALK [HGNC Gene ID: 427] is a chromosomal abnormality found in various histologic types of non-small-cell lung cancer (NSCLC). The fusion encodes for the EML4-ALK protein, which promotes and maintains cancer cell growth. The detection of EML4-ALK may be useful for predicting the potential response to ALK inhibitors as a therapeutic option for patients with lung cancer. PMID: 19170230 Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

LOINC Names Get Info

Fully-Specified Name
inv(2)(p21;p23)(EML4,ALK) fusion transcript:PrThr:Pt:Bld/Tiss:Ord:FISH
Long Common Name
inv(2)(p21;p23)(EML4,ALK) fusion transcript [Presence] in Blood or Tissue by FISH
Short Name
inv(2)(EML4,ALK) Bld/T Ql FISH
Display Name
inv(2)(p21;p23)(EML4,ALK) fusion transcript FISH Ql (Bld/Tiss)
Consumer Name Alpha Get Info
inv(2)(p21;p23)(EML4,ALK) fusion transcript analysis, Blood or tissue specimen

Part Model Get Info

  • Component
    inv(2)(p21;p23)(EML4,ALK) fusion transcript
    LP228722-7
    • Analyte
      inv(2)(p21;p23)(EML4,ALK) fusion transcript
      LP228722-7
      • Component Numerator
        inv(2)(p21;p23)(EML4,ALK) fusion transcript
        LP228722-7
        • Component Numerator Core
          inv(2)(p21;p23)(EML4,ALK)
          LP200476-2
        • Component Numerator Core Suffix
          fusion transcript
          LP150217-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    FISH
    LP62864-1

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MOLPATH.INV
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.61 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Fúzní transkript inv(2)(p21;p23)(EML4,ALK):Přítomnost nebo práh:Časový bod:Krev/tkáň:Ordinální:Fluorescenční in situ hybridizace (FISH)
el-GRGreek (Greece)inv(2)(p21;p23)(EML4,ALK) μεταγραφή συγχώνευσης:PrThr:Pt:Αίμα/Ιστός:Ord:Φθορίζουσα υβριδοποίηση in situ
Synonyms: inv(2)(p21;p23)(EML4,ALK) MOLPATH MOLPATH.INV Ord PrThr Pt Αίμα Αίμα/Ιστός Ιστός μεταγραφή συγχώνευσης Φθορίζουσα υβριδοποίηση in situ
es-ESSpanish (Spain)inv(2)(p21;p23)(EML4,ALK) Tránscritos de fusión:PrThr:Punto temporal:Sangre o tejido:Ord:Hibridación in situ fluoresente (FISH)
es-MXSpanish (Mexico)transcrito de fusión inv (2) (p21; p23) (EML4, ALK):Presencia o umbral:Punto temporal:Sangre o tejido:Ordinal:Hibridación fluorescente in situ (FISH)
fr-FRFrench (France)inv(2)(p21;p23)(EML4,ALK) transcript de fusion:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:FISH
fr-CAFrench (Canada)inv(2)(p21;p23)(EML4,ALK) transcrit de fusion:Présence-Seuil:Temps ponctuel:Sang/Tissu:Ordinal:Hybridation fluorescente in situ
it-ITItalian (Italy)p23)(EML4,ALK)","inv(2)(p21, trascritto di fusione:PrThr:Pt:Sangue/Tess:Ord:FISH
Synonyms: Ibridazione in situ fluorescente (FISH) Inversione genetica p23)(EML4,ALK)",,06/08/2026 23:57:37 Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NLDutch (Netherlands)inv(2)(p21;p23)(EML4,ALK) fusietranscript:aanwezigheid:moment:bloed of weefsel:ordinaal:FISH
pl-PLPolish (Poland)Inv(2)(p21;p23)(EML4,ALK) transkrypt fuzyjny:granica wykrywalności:punkt w czasie:krew lub tkanka:uporządkowany:FISH
Synonyms: fluorescencyjna hybrydyzacja in situ
tr-TRTurkish (Turkey)inv(2)(p21;p23)(EML4,ALK) füzyon transkript:MevcEşik:Zmlı:Kan/Dk:Srl:FISH
Synonyms: Mevcut
zh-CNChinese (China)inv(2)(p21;p23)(EML4,ALK) 融合转录物:存在情况或阈值:时间点:全血/组织:序数型:FISH
Synonyms: Ⅱ Fluorescent in situ hybridization;荧光原位杂交 II 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 倒位(2)(p21;p23)(EML4,ALK);基因倒位;基因倒置;倒位;倒置;gene inversion 全血或组织;血液/组织;血液或组织 分子病理学.基因倒位;分子病理学试验.基因倒位;分子病理学试验类.倒位 分子病理学;分子病理学试验 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 间变型淋巴瘤激酶 间变性淋巴瘤激酶（anaplastic lymphoma kinase，ALK）

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79206-9