79323-2
7-Isobiopterin/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP200448-1 7-Isobiopterin
7-Isobiopterin (also known as 7-biopterin or primapterin) [PubChem: 5488923], is a pterin derivative of 4a-hydroxy-BH4. In healthy patients, tetrahydrobiopterin (BH4) is converted to 4a-hydroxy-BH4 with a concomitant conversion of phenylalanine to tyrosine, and BH4 is subsequently regenerated via a pathway that includes pterin-4a-carbinolamine dehydratase (PCD), which is encoded by the PCBD gene. Mutations in the PCBD gene are associated with decreased PCD activity, which results in decreased BH4 salvage, increase in phenylalanine due to inhibition of the BH4 to 4a-hydroxy-BH4 reaction, and concomitant increase in 7-biopterin in urine due to alternate metabolism of 4a-hydroxy-BH4. PMCID: PMC1377166 [UniProt: P61457]
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- 7-Isobiopterin/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 7-Isobiopterin/Creatinine [Molar ratio] in Urine
- Short Name
- 7-Isobiopterin/Creat Ur-sRto
- Display Name
- 7-Isobiopterin/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- 7-Isobiopterin/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80170-4 | Pterins panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | 7-isobiopterina/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 7-isobiopterina / creatinina: |
| fr-FR | French (France) | 7-Isobioptérine/créatinine: |
| it-IT | Italian (Italy) | 7-Isobiopterin/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
| nl-NL | Dutch (Netherlands) | 7-isobiopterine/creatinine: Synonyms: kreatinine |
| tr-TR | Turkish (Turkey) | 7-Izobiopterin/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 7-异生物蝶呤/肌酐: Synonyms: 7-异生物喋呤 CR; |
Example Units
| Unit | Source |
|---|---|
| nmol/mmol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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