79398-4
Prolactin isoforms pattern [Interpretation] in Serum or Plasma Narrative
Active
Part Description
LP200143-8 Prolactin isoforms pattern
Monomeric prolactin is the most common form of circulating prolactin. Prolactin also has several isoforms, including the dimeric form ("big-prolactin") that has a molecular weight of ~50 kD and polymeric form ("big-big prolactin") that has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302
Source: Regenstrief LOINC,
Fully-Specified Name
- Component
- Prolactin isoforms pattern
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Additional Names
- Long Common Name
- Prolactin isoforms pattern [Interpretation] in Serum or Plasma Narrative
- Short Name
- Prolactin isoforms pattern SerPl-Imp
- Display Name
- Prolactin isoforms pattern Nar [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Prolactin isoforms pattern test result, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
78993-3 | Prolactin isoforms panel - Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Patrón isoformas de prolactina: |
es-MX | Spanish (Mexico) | Patrón de isoformas de prolactina: |
fr-FR | French (France) | Prolactine isoformes profil: |
it-IT | Italian (Italy) | Profilo di isoforme della prolattina: Synonyms: Chimica Impressione/interpretazione di studio Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | prolactine isovormen patroon: |
tr-TR | Turkish (Turkey) | Prolaktin izoformları örüntüsü: Synonyms: Prolaktin izoformları patterni |
zh-CN | Chinese (China) | 催乳素同工型模式: Synonyms: PRL; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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