Version 2.78

79413-1 Dothiepin+Nordothiepin [Mass/volume] in Serum or Plasma --trough

Term Description

Specimen is drawn at the expected trough (baseline) level of the parent drug (Dothiepin).
Source: Regenstrief LOINC

Part Descriptions

LP199563-0   Dothiepin+Nordothiepin
Dothiepin (or dosulepin) is a tricyclic antidepressant marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress. Dothiepin is used for the treatment of major depressive disorder and neuropathic pain. PMID: 2670509 Common side effects include dry mouth, drowsiness, tremor, hypotension, nausea and tachycardia. Dothiepin and its metabolites, such as nordothiepin and dothiepin sulfoxide (dothiepin S-oxide), are measured to evaluate drug toxicity. Source: Regenstrief LOINC

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
Dothiepin+Nordothiepin^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Dothiepin+Nordothiepin Trough SerPl-mCnc
Display Name
Dothiepin+Nordothiepin trough [Mass/Vol]
Consumer Name Alpha Get Info
Dothiepin+Nordothiepin trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79409-9 Dothiepin+nordothiepin trough and dothiepin sulfoxide panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Dothiepin + Nordothiepin ^ canal:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Dotiepina+Nordotiepina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Dosulépine+Nordothiépine taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Dotiepina+Nordotiepina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Dotiepina e Nordotiepina Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) dothiepine + nordothiepine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
tr-TR Turkish (Turkey) Dotiepin+Nordotiepin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 度硫平+去甲基度硫平^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 二苯噻庚英;度琉平 去甲度硫平;去甲基二苯噻庚英;去甲基度琉平;脱甲基度硫平 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 度硫平(二苯噻庚英、度琉平)+去甲基度硫平(去甲度硫平、去甲基二苯噻庚英、去甲基度琉平、脱甲基度硫平) 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ug/L Example UCUM Units

35120-5 Dothiepin sulfoxide [Mass/volume] in Serum or Plasma

Part Descriptions

LP33042-0   Dothiepin sulfoxide
Dothiepin (or dosulepin) is a tricyclic antidepressant marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress. Dothiepin is used for the treatment of major depressive disorder and neuropathic pain. PMID: 2670509 Common side effects include dry mouth, drowsiness, tremor, hypotension, nausea and tachycardia. Dothiepin and its metabolites, such as nordothiepin and dothiepin sulfoxide (dothiepin S-oxide), are measured to evaluate drug toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
Dothiepin sulfoxide
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Dothiepin sulfoxide SerPl-mCnc
Display Name
Dothiepin sulfoxide [Mass/Vol]
Consumer Name Alpha Get Info
Dothiepin sulfoxide, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.40
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
85089-1 Dothiepin and nordothiepin and dothiepin sulfoxide panel - Serum or Plasma
79409-9 Dothiepin+nordothiepin trough and dothiepin sulfoxide panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) sulfóxido de dotiepina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-MX Spanish (Mexico) Sulfóxido de dothiepin:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Sulfóxido de dotiepina:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Dotiepiinsulfoksiid:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Dosulépine sulfoxide:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Sulfoxyde de dosulépine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CA French (Canada) Sulfoxyde de dosulépine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Dotiepina solfossido:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 도티에핀 술폭시드:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) dothiepinesulfoxide:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Sulfóxido Dotiepina:MCnc:Pt:Sor/Plas:Qn:
Synonyms: Dothiepin metAcolite; Prothiaden; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Дотиепин сульфоксид:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Dotiepin sülfoksit:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 度硫平亚砜:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 二苯噻庚英;度琉平 二苯噻庚英亚砜;度琉平亚砜;度硫平代谢产物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ug/L Example UCUM Units