79409-9
Dothiepin+nordothiepin trough and dothiepin sulfoxide panel - Serum or Plasma
Active
79413-1 Dothiepin+Nordothiepin [Mass/volume] in Serum or Plasma --trough
Term Description
Specimen is drawn at the expected trough (baseline) level of the parent drug (Dothiepin).
Part Descriptions
LP199563-0 Dothiepin+Nordothiepin
Dothiepin (or dosulepin) is a tricyclic antidepressant marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress. Dothiepin is used for the treatment of major depressive disorder and neuropathic pain. PMID: 2670509 Common side effects include dry mouth, drowsiness, tremor, hypotension, nausea and tachycardia. Dothiepin and its metabolites, such as nordothiepin and dothiepin sulfoxide (dothiepin S-oxide), are measured to evaluate drug toxicity.
Source: Regenstrief LOINC
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
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Source: Wikipedia, Trough levels for therapeutic drug monitoring
Fully-Specified Name
- Component
- Dothiepin+Nordothiepin^trough
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54 (MIN)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79409-9 | Dothiepin+nordothiepin trough and dothiepin sulfoxide panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Dothiepin+nordothiepin^Údolní koncentrace: |
| el-GR | Greek (Greece) | Δοθιεπίνη+Νορδοθιεπίνη^ελάχιστα επίπεδα: Synonyms: DRUG/TOX MCnc Pt Qn Δοθιεπίνη Δοθιεπίνη+Νορδοθιεπίνη ελάχιστα επίπεδα Νορδοθιεπίνη Ορός Ορός/Πλάσμα Πλάσμα |
| es-ES | Spanish (Spain) | Dotiepina+Nordotiepina^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Dothiepin + Nordothiepin ^ canal: |
| fr-FR | French (France) | Dothiépine+nordothiépine^taux résiduel: |
| it-IT | Italian (Italy) | Dotiepina+Nordotiepina^valore minimo: Synonyms: Concentrazione di Massa Dotiepina e Nordotiepina Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
| nl-NL | Dutch (Netherlands) | dothiepine + nordothiepine^dalspiegel: |
| tr-TR | Turkish (Turkey) | Dotiepin+Nordotiepin^en düşük: Synonyms: çukur düzey |
| zh-CN | Chinese (China) | 度硫平+去甲基度硫平^波谷: Synonyms: 一剂药物的初始剂量; |
Example Units
| Unit | Source |
|---|---|
| ug/L | Example UCUM Units |
35120-5 Dothiepin sulfoxide [Mass/volume] in Serum or Plasma
Part Descriptions
LP33042-0 Dothiepin sulfoxide
Dothiepin (or dosulepin) is a tricyclic antidepressant marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress. Dothiepin is used for the treatment of major depressive disorder and neuropathic pain. PMID: 2670509 Common side effects include dry mouth, drowsiness, tremor, hypotension, nausea and tachycardia. Dothiepin and its metabolites, such as nordothiepin and dothiepin sulfoxide (dothiepin S-oxide), are measured to evaluate drug toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Dothiepin sulfoxide
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.11
- Last Updated
- Version 2.40 (MIN)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85089-1 | Dothiepin and nordothiepin and dothiepin sulfoxide panel - Serum or Plasma |
| 79409-9 | Dothiepin+nordothiepin trough and dothiepin sulfoxide panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Dothiepin sulfoxid: |
| el-GR | Greek (Greece) | Σουλφοξείδιο δοθιεπίνης: Synonyms: DRUG/TOX MCnc Pt Qn Δοθιεπίνη Ορός Ορός/Πλάσμα Πλάσμα Σουλφοξείδιο δοθιεπίνης |
| es-AR | Spanish (Argentina) | sulfóxido de dotiepina: |
| es-ES | Spanish (Spain) | Sulfóxido de dotiepina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Sulfóxido de dothiepin: |
| et-EE | Estonian (Estonia) | Dotiepiinsulfoksiid: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Sulfoxyde de dosulépine: |
| fr-FR | French (France) | Dosulépine sulfoxide: |
| fr-BE | French (Belgium) | Sulfoxyde de dosulépine: |
| it-IT | Italian (Italy) | Dotiepina solfossido: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 도티에핀 술폭시드: |
| nl-NL | Dutch (Netherlands) | dothiepinesulfoxide: |
| pl-PL | Polish (Poland) | Sulfotlenek dotiepiny: Synonyms: Dosulepina Sulfotlenek dosulepiny |
| pt-BR | Portuguese (Brazil) | Sulfóxido Dotiepina: Synonyms: Dothiepin metAcolite; |
| ru-RU | Russian (Russian Federation) | Дотиепин сульфоксид: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Dotiepin sülfoksit: |
| zh-CN | Chinese (China) | 度硫平亚砜: Synonyms: 二苯噻庚英; |
Example Units
| Unit | Source |
|---|---|
| ug/L | Example UCUM Units |