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Term Description

Specimen is drawn at the expected trough (baseline) level of the parent drug (Dothiepin).

Part Descriptions

LP199563-0   Dothiepin+Nordothiepin
Dothiepin (or dosulepin) is a tricyclic antidepressant marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress. Dothiepin is used for the treatment of major depressive disorder and neuropathic pain. PMID: 2670509 Common side effects include dry mouth, drowsiness, tremor, hypotension, nausea and tachycardia. Dothiepin and its metabolites, such as nordothiepin and dothiepin sulfoxide (dothiepin S-oxide), are measured to evaluate drug toxicity. Source: Regenstrief LOINC

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LOINC Names Get Info

Fully-Specified Name
Dothiepin+Nordothiepin^trough:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Dothiepin+Nordothiepin [Mass/volume] in Serum or Plasma --trough
Short Name
Dothiepin+Nordothiepin Trough SerPl-mCnc
Display Name
Dothiepin+Nordothiepin trough [Mass/Vol]
Consumer Name Alpha Get Info
Dothiepin+Nordothiepin trough, Blood

Part Model Get Info

  • Component
    Dothiepin+Nordothiepin^trough
    LP307893-0
    • Analyte
      Dothiepin+Nordothiepin
      LP199563-0
      • Component Numerator
        Dothiepin+Nordothiepin
        LP199563-0
        • Component Numerator Core
          Dothiepin+Nordothiepin
          LP199563-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      trough
      LP20176-1
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
79409-9Dothiepin+nordothiepin trough and dothiepin sulfoxide panel - Serum or Plasma

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Dothiepin+nordothiepin^Údolní koncentrace:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Δοθιεπίνη+Νορδοθιεπίνη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Δοθιεπίνη Δοθιεπίνη+Νορδοθιεπίνη ελάχιστα επίπεδα Νορδοθιεπίνη Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)Dotiepina+Nordotiepina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Dothiepin + Nordothiepin ^ canal:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)Dothiépine+nordothiépine^taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Dotiepina+Nordotiepina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Dotiepina e Nordotiepina Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NLDutch (Netherlands)dothiepine + nordothiepine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
tr-TRTurkish (Turkey)Dotiepin+Nordotiepin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CNChinese (China)度硫平+去甲基度硫平^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 二苯噻庚英;度琉平 去甲度硫平;去甲基二苯噻庚英;去甲基度琉平;脱甲基度硫平 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 度硫平（二苯噻庚英、度琉平）+去甲基度硫平（去甲度硫平、去甲基二苯噻庚英、去甲基度琉平、脱甲基度硫平） 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

UnitSource
ug/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79413-1