79572-4
Folate and tryptophan and metabolites panel - Cerebral spinal fluid
Active
Term Description
Testing for folate and its metabolites as well as tryptophan and its metabolites in CSF can be useful in distinguishing among various central nervous system disorders associated with folate deficiency. Low folate levels are associated with inborn errors of metabolism, including cerebral folate deficiency (CFD), a neurological syndrome that occurs around 2-4 months of age and is primarily associated with associated with low levels of 5-methyltetrahydrofolate (5-MTHF) in the CSF with normal folate levels in the plasma and red blood cells.[PMID: 19260931] Low folate levels are also associated with depression and dementia in elderly patients.[PMID: 11183038] Serotonin, which is formed from tryptophan, may be the link between folate and depression or dementia. Many patients with neuropsychiatric disorders and folate deficiency have also been found to have low levels of 5-hydroxyindoleacetic acid (5-HIAA, a serotonin metabolite), and patients with 5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency also have decreased serotonin synthesis. [PMCID: 1810582]
Source: Regenstrief LOINC
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
---|---|---|---|---|
79572-4 | Folate and tryptophan and metabolites panel - Cerebral spinal fluid | |||
Indent47547-5 | 5-Methyltetrahydrofolate [Moles/volume] in Cerebral spinal fluid | nmol/L | ||
Indent75048-9 | Tetrahydrofolate [Moles/volume] in Cerebral spinal fluid | umol/L | ||
Indent26602-3 | Tryptophan [Moles/volume] in Cerebral spinal fluid | umol/L | ||
Indent47544-2 | 5-Hydroxyindoleacetate [Moles/volume] in Cerebral spinal fluid | nmol/L | ||
Indent47546-7 | 5-Hydroxytryptophan [Moles/volume] in Cerebral spinal fluid | nmol/L | ||
Indent79574-0 | Folate and tryptophan and metabolites pattern [Interpretation] in Cerebral spinal fluid Narrative |
Fully-Specified Name
- Component
- Folate & tryptophan & metabolites panel
- Property
- -
- Time
- Pt
- System
- CSF
- Scale
- -
- Method
Additional Names
- Short Name
- Folate + Tryp + Metabs Pnl CSF
- Display Name
- Folate and tryptophan and metabolites panel (CSF)
- Consumer Name Alpha
- Folate and Tryptophan and Metabolites panel, Spinal fluid
Basic Attributes
- Class
- PANEL.CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Order
- Panel Type
- Panel
Language Variants
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 叶酸与色氨酸与代谢产物组套: Synonyms: |
es-ES | Spanish (Spain) | Panel de folato y triptofano y metabolitos: |
it-IT | Italian (Italy) | Folato & Triptofano & Metaboliti, panel: Synonyms: |
fr-FR | French (France) | Folate et tryptophane et métabolites panel: |
nl-NL | Dutch (Netherlands) | folaat & tryptofaan & metabolieten panel: Synonyms: |
es-MX | Spanish (Mexico) | Panel de folato, triptófano y metabolitos: |
LOINC Terminology Service (API) using HL7® FHIR®
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=79572-4 - Questionnaire definition
- https:
//fhir.loinc.org/Questionnaire/?url=http: //loinc.org/q/79572-4
LOINC Copyright
Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright