Version 2.74

Term Description

Testing for folate and its metabolites as well as tryptophan and its metabolites in CSF can be useful in distinguishing among various central nervous system disorders associated with folate deficiency. Low folate levels are associated with inborn errors of metabolism, including cerebral folate deficiency (CFD), a neurological syndrome that occurs around 2-4 months of age and is primarily associated with associated with low levels of 5-methyltetrahydrofolate (5-MTHF) in the CSF with normal folate levels in the plasma and red blood cells.[PMID: 19260931] Low folate levels are also associated with depression and dementia in elderly patients.[PMID: 11183038] Serotonin, which is formed from tryptophan, may be the link between folate and depression or dementia. Many patients with neuropsychiatric disorders and folate deficiency have also been found to have low levels of 5-hydroxyindoleacetic acid (5-HIAA, a serotonin metabolite), and patients with 5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency also have decreased serotonin synthesis. [PMCID: 1810582]
Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
79572-4 Folate and tryptophan and metabolites panel - Cerebral spinal fluid
Indent47547-5 5-Methyltetrahydrofolate [Moles/volume] in Cerebral spinal fluid nmol/L
Indent75048-9 Tetrahydrofolate [Moles/volume] in Cerebral spinal fluid umol/L
Indent26602-3 Tryptophan [Moles/volume] in Cerebral spinal fluid umol/L
Indent47544-2 5-Hydroxyindoleacetate [Moles/volume] in Cerebral spinal fluid nmol/L
Indent47546-7 5-Hydroxytryptophan [Moles/volume] in Cerebral spinal fluid nmol/L
Indent79574-0 Folate and tryptophan and metabolites pattern [Interpretation] in Cerebral spinal fluid Narrative

Fully-Specified Name

Component
Folate & tryptophan & metabolites panel
Property
-
Time
Pt
System
CSF
Scale
-
Method

Additional Names

Short Name
Folate + Tryp + Metabs Pnl CSF
Display Name
Folate and tryptophan and metabolites panel (CSF)
Consumer Name Alpha
Folate and Tryptophan and Metabolites panel, Spinal fluid

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation
Order
Panel Type
Panel

Language Variants

Tag Language Translation
zh-CN Chinese (China) 叶酸与色氨酸与代谢产物组套:-:时间点:脑脊液:-:
Synonyms: B 吲哚基丙氨酸;Beta 吲哚基丙氨酸;L-色氨酸;Trp;β吲哚基丙氨酸 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Vit M;维生素 Bc;维生素 M;蝶酰谷氨酸 代谢产物 代谢废物 代谢废物类 代谢物 代谢物类 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.化学试验;化学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;化学医嘱组类;医嘱组.化学;医嘱组.化学检验项目;医嘱组类.化学;医嘱组类.化学检验项目;医嘱组类.化学试验;实验室医嘱组类.化学;实验室医嘱组类.化学检验项目;实验室医嘱组类.化学试验 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 叶酸（Folic acid、Folate、维生素B9、维生素Bc、Vit M、维生素 M、蝶酰谷氨酸）与色氨酸（B 吲哚基丙氨酸、Beta 吲哚基丙氨酸、L-色氨酸、Trp、β吲哚基丙氨酸）相关吲哚（靛基质）与（及）代谢产物（代谢物、新陈代谢产物）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液
es-ES Spanish (Spain) Panel de folato y triptofano y metabolitos:Propiedades mixtas (sólo paneles):Punto temporal:Líquido Cefalorraquideo:-:
it-IT Italian (Italy) Folato & Triptofano & Metaboliti, panel:-:Pt:LCS:-:
Synonyms: Chimica Liquido cerebrospinale Panel Folato e Triptofano e Metaboliti Punto nel tempo (episodio) Set di prescrizione chimica
fr-FR French (France) Folate et tryptophane et métabolites panel:-:Ponctuel:Liquide céphalorachidien:-:
nl-NL Dutch (Netherlands) folaat & tryptofaan & metabolieten panel:-:moment:liquor cerebrospinalis:-:
Synonyms: foliumzuur; vitamine B11
es-MX Spanish (Mexico) Panel de folato, triptófano y metabolitos:-:Punto temporal:Fluído espinal cerebral:-:

LOINC Terminology Service (API) using HL7® FHIR®

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79572-4
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/79572-4