79583-1
R- and S-beta aminoisobutyrate and D- and L-serine panel - Serum or Plasma
Active
79615-1 R-beta aminoisobutyrate [Moles/volume] in Serum or Plasma
Part Descriptions
LP201654-3 R-beta aminoisobutyrate
Beta aminoisobutyric acid (BAIB) is a nonprotein amino acid that is an end product of pyrimidine metabolism. The R and S enantiomers (previously named D-(minus)-BAIB and L-plus-BAIB) are produced from thymine and L-valine, respectively. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with dihydropyrimidine dehydrogenase deficiency, thymine catabolism is decreased, which results in moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated despite decreased breakdown of thymine, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Deficiency of D-beta-aminoisobutyrate:pyruvate aminotransferase (EC 2.6.1.40) , an enzyme that is involved in the catabolism R-BAIB, also results in elevated urine BAIB and is associated with hyperuricemia. [OMIM: 210100]
Source: Regenstrief LOINC, PMID: 14705962
Fully-Specified Name
- Component
- R-beta aminoisobutyrate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- R-B-AIB SerPl-sCnc
- Display Name
- R-beta aminoisobutyrate [Moles/Vol]
- Consumer Name Alpha Get Info
- R-beta aminoisobutyrate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79583-1 | R- and S-beta aminoisobutyrate and D- and L-serine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | R-beta aminoisobutirato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | R-beta aminoisobutirato: |
| fr-FR | French (France) | R-bêta aminoisobutyrate: |
| it-IT | Italian (Italy) | R-Beta aminoisobutirrato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | R-bèta-aminoisobutyraat: |
| tr-TR | Turkish (Turkey) | R-beta aminoizobütirat: |
| zh-CN | Chinese (China) | R-beta 氨基异丁酸: Synonyms: 3-氨基异丁酸; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
79604-5 S-beta aminoisobutyrate [Moles/volume] in Serum or Plasma
Part Descriptions
LP201653-5 S-beta aminoisobutyrate
Beta aminoisobutyric acid (BAIB) is a nonprotein amino acid that is an end product of pyrimidine metabolism. The R and S enantiomers (previously named D-(minus)-BAIB and L-plus-BAIB) are produced from thymine and L-valine, respectively. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with dihydropyrimidine dehydrogenase deficiency, thymine catabolism is decreased, which results in moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated despite decreased breakdown of thymine, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Deficiency of D-beta-aminoisobutyrate:pyruvate aminotransferase (EC 2.6.1.40) , an enzyme that is involved in the catabolism R-BAIB, also results in elevated urine BAIB and is associated with hyperuricemia. [OMIM: 210100]
Source: Regenstrief LOINC, PMID: 14705962
Fully-Specified Name
- Component
- S-beta aminoisobutyrate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- S-B-AIB SerPl-sCnc
- Display Name
- S-beta aminoisobutyrate [Moles/Vol]
- Consumer Name Alpha Get Info
- S-beta aminoisobutyrate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79583-1 | R- and S-beta aminoisobutyrate and D- and L-serine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | S-beta aminoisobutirato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | S-beta aminoisobutirato: |
| fr-FR | French (France) | S-bêta aminoisobutyrate: |
| it-IT | Italian (Italy) | S-Beta aminoisobutirrato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | S-bèta-aminoisobutyraat: |
| tr-TR | Turkish (Turkey) | S-beta aminoizobütirat: |
| zh-CN | Chinese (China) | S-beta 氨基异丁酸: Synonyms: 3-氨基异丁酸; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
79610-2 D-serine [Moles/volume] in Serum or Plasma
Part Descriptions
LP201661-8 D-serine
D-serine (D-ser) is a major endogenous NMDA receptor co-agonist that specifically activates pre-synaptic NMDA receptors. D-ser is produced from L-serine by the enzyme serine racemase. Altered D-ser concentration may be associated with a number of central nervous disorders, including schizophrenia, aging, Alzheimer's disease, anxiety, cerebellar ataxia, Parkinson's disease, neuropathic pain and depression. Increasing the level of CNS D-ser by direct supplementation, or increasing production or decreasing breakdown of D-ser is being studied as a treatment option for conditions such as schizophrenia and Parkinson's disease.
PMID: 22987851
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- D-serine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- D-serine SerPl-sCnc
- Display Name
- D-serine [Moles/Vol]
- Consumer Name Alpha Get Info
- D-serine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79583-1 | R- and S-beta aminoisobutyrate and D- and L-serine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | D-serina: |
| es-ES | Spanish (Spain) | D-serina: Synonyms: Cuantitativo |
| fr-FR | French (France) | D-sérine: |
| it-IT | Italian (Italy) | D-serina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | D-serine: |
| tr-TR | Turkish (Turkey) | D-serin: |
| zh-CN | Chinese (China) | D-丝氨酸: Synonyms: Rh; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
79618-5 L-serine [Moles/volume] in Serum or Plasma
Part Descriptions
LP201662-6 L-serine
L-serine (L-ser) is an amino acid that plays a central role in cellular proliferation and is the major source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. L-ser is converted to D-ser by serine racemase. Altered CNS D-ser levels have been associated with a variety of neurologic conditions, including schizophrenia and Parkinson's disease. L-ser also plays a specific role in the CNS, and patients with defects of L-ser synthesis have significant neurological impairment. Two enzyme defects linked to L-ser synthesis have been discovered: 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency and phosphoserine phosphatase (PSP) deficiency. Patients with 3-PGDH deficiency can have significant neurologic impairment, including congenital microcephaly and seizures associated with decreased white matter volume and myelination, and L-ser supplementation has been used to treat the seizures in this patient population. PSP deficiency has only been identified in one patient, whose symptoms also improved with L-ser treatment. PMID: 12534373
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- L-serine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- L-serine SerPl-sCnc
- Display Name
- L-serine [Moles/Vol]
- Consumer Name Alpha Get Info
- L-serine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79583-1 | R- and S-beta aminoisobutyrate and D- and L-serine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | L-serina: |
| es-ES | Spanish (Spain) | L-serina: Synonyms: Cuantitativo |
| fr-FR | French (France) | L-sérine: |
| it-IT | Italian (Italy) | L-serina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | L-serine: |
| tr-TR | Turkish (Turkey) | L-serin: |
| zh-CN | Chinese (China) | L-丝氨酸: Synonyms: Ser 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
79630-0 R- and S-beta aminoisobutyrate and D- and L-serine pattern [Interpretation] in Serum or Plasma Narrative
Fully-Specified Name
- Component
- R- & S-beta aminoisobutyrate & D- & L-serine pattern
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Additional Names
- Short Name
- R- + S-BAIB + D- + L-ser patt SerPl-Imp
- Display Name
- R- and S-beta aminoisobutyrate and D- and L-serine pattern Nar [Interp]
- Consumer Name Alpha Get Info
- Interpretation of R- and S-beta aminoisobutyrate and D- and L-serine pattern test result, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79583-1 | R- and S-beta aminoisobutyrate and D- and L-serine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | R- & S-beta aminoisobutirato y patrón D- & L-serina: |
| es-ES | Spanish (Spain) | Patrón R-y S-betaaminoisobutirato y D- y L- serina: |
| fr-FR | French (France) | R-bêta aminoisobutyrate et S-bêta aminoisobutyrate et D-sérine et L-sérine Profil: |
| it-IT | Italian (Italy) | R- & S-Beta aminoisobutirrato D- & L-serina,profilo: Synonyms: Chimica Impressione/interpretazione di studio Plasma Profilo di R- e S-Beta aminoisobutirrato D- e L-s Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | R- & S-bèta aminoisobutyraat & D- & L-serine patroon: |
| tr-TR | Turkish (Turkey) | R- ve S-beta aminoizobütirat ve D- ve L-serin örüntüsü: Synonyms: R- ve S-beta aminoizobütirat ve D- ve L-serin paterni |
| zh-CN | Chinese (China) | R- 与 S-beta 氨基异丁酸与 D- 与 L-丝氨酸模式: Synonyms: 3-氨基异丁酸; |