Version 2.78

Part Description

LP200579-3   S-adenosylhomocysteine
S-Adenosylhomocysteine (SAH) is formed by the demethylation of S-adenosylmethionine (SAMe) and is rapidly metabolized to homocysteine. The reaction of SAH to homocysteine is catalyzed by S-adenosylhomocysteine hydrolase and is reversible with the equilibrium favoring formation of SAH. Therefore, increased levels of SAH may occur when the intracellular concentration of homocysteine increases. Since SAH is known to inhibit methylation dependent reactions, the ratio of SAMe to SAH is often used as an index of methylation status. Disturbances in the transmethylation pathway indicated by abnormal SAMe, SAH or their ratio have been reported in many neurodegenerative diseases, such as dementia, depression or Parkinson's disease. PMID: 17892439 Source: Regenstrief LOINC

Fully-Specified Name

Component
S-adenosylhomocysteine
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
SAH SerPl-sCnc
Display Name
S-adenosylhomocysteine [Moles/Vol]
Consumer Name Alpha Get Info
S-adenosylhomocysteine, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
80178-7 S-adenosylmethionine and S-adenosylhomocystine panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) S-adenosilhomocistina:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) S-adenosilhomocisteína:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) S-Adénosylhomocystéine:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) S-adenosilomocisteina:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) S-adenosylhomocysteïne:mol/volume:moment:serum of plasma:kwantitatief:
tr-TR Turkish (Turkey) S-adenozilhomosistein:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) S-腺苷同型半胱氨酸:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: S 型 S-腺苷基同型半胱氨酸;S-腺苷巯基丁氨酸;S-腺苷高半胱氨酸 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80175-3