80178-7
S-adenosylmethionine and S-adenosylhomocystine panel - Serum or Plasma
Active
80175-3 S-adenosylhomocysteine [Moles/volume] in Serum or Plasma
Part Descriptions
LP200579-3 S-adenosylhomocysteine
S-Adenosylhomocysteine (SAH) is formed by the demethylation of S-adenosylmethionine (SAMe) and is rapidly metabolized to homocysteine. The reaction of SAH to homocysteine is catalyzed by S-adenosylhomocysteine hydrolase and is reversible with the equilibrium favoring formation of SAH. Therefore, increased levels of SAH may occur when the intracellular concentration of homocysteine increases. Since SAH is known to inhibit methylation dependent reactions, the ratio of SAMe to SAH is often used as an index of methylation status. Disturbances in the transmethylation pathway indicated by abnormal SAMe, SAH or their ratio have been reported in many neurodegenerative diseases, such as dementia, depression or Parkinson's disease. PMID: 17892439
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- S-adenosylhomocysteine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- SAH SerPl-sCnc
- Display Name
- S-adenosylhomocysteine [Moles/Vol]
- Consumer Name Alpha Get Info
- S-adenosylhomocysteine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80178-7 | S-adenosylmethionine and S-adenosylhomocystine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | S-adenosilhomocisteína: |
| es-ES | Spanish (Spain) | S-adenosilhomocistina: Synonyms: Cuantitativo |
| fr-FR | French (France) | S-Adénosylhomocystéine: |
| it-IT | Italian (Italy) | S-adenosilomocisteina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | S-adenosylhomocysteïne: |
| tr-TR | Turkish (Turkey) | S-adenozilhomosistein: |
| zh-CN | Chinese (China) | S-腺苷同型半胱氨酸: Synonyms: S 型 S-腺苷基同型半胱氨酸; |
Example Units
| Unit | Source |
|---|---|
| nmol/L | Example UCUM Units |
78966-9 S-adenosylmethionine [Moles/volume] in Serum or Plasma
Part Descriptions
LP199517-6 S-adenosylmethionine
S-adenosylmethionine (SAMe) is the major methyl donor involved in enzymatic transmethylation reactions in proteins, DNA, phospholipids and neurotransmitters. It plays a key role in the maintenance of human health and in the prevention of disease. PMID: 9300919 Decreased SAMe levels often occur in the presence of folate and cobalamin (vitamin B12) deficiency. PMID: 23538072 Low SAMe levels have been associated with depression, dementia, and liver disease.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- S-adenosylmethionine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- SAMe SerPl-sCnc
- Display Name
- S-adenosylmethionine [Moles/Vol]
- Consumer Name Alpha Get Info
- S-adenosylmethionine, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80178-7 | S-adenosylmethionine and S-adenosylhomocystine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | S-adenosilmetionina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | S-adenosilmetionina: |
| fr-FR | French (France) | S-Adénosylméthionine: |
| it-IT | Italian (Italy) | Adenosilmetionina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | S-adenosylmethionine: |
| tr-TR | Turkish (Turkey) | S-adenozilmetiyonin: |
| zh-CN | Chinese (China) | S-腺苷蛋氨酸: Synonyms: S 型 S-腺苷甲硫氨酸 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| nmol/L | Example UCUM Units |
80181-1 S-adenosylmethionine and S-adenosylhomocystine pattern [Interpretation] in Serum or Plasma Narrative
Term Description
S-adenosylhomocysteine (SAH) and S-adenosylmethionine (SAM) levels are measured when investigating folate and vitamin B12 deficiency, and the ratio of SAH to SAM is also used as a measure of methylation status. Low levels of SAM have also been associated with depression, dementia, vacuolar myelopathy and liver disease.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- S-adenosylmethionine & S-adenosylhomocystine pattern
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Additional Names
- Panel Name
- Short Name
- SAMe and SAH pattern SerPl-Imp
- Display Name
- S-adenosylmethionine and S-adenosylhomocystine pattern Nar [Interp]
- Consumer Name Alpha Get Info
- Interpretation of S-adenosylmethionine and S-adenosylhomocystine pattern test result, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80178-7 | S-adenosylmethionine and S-adenosylhomocystine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Patrón de S-adenosilmetionina y S-adenosilhomocistina: |
| es-ES | Spanish (Spain) | Patrón de S-adenosilmetionina y S-adenosilhomocistina: |
| fr-FR | French (France) | S-Adénosylméthionine et S-Adénosylhomocystéine Profil: |
| it-IT | Italian (Italy) | S-adenosilmetionina&S-adenosilomocisteina, profilo: Synonyms: Chimica Impressione/interpretazione di studio Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | S-adenosylmethionine & S-adenosylhomocystine patroon: |
| tr-TR | Turkish (Turkey) | S-adenozilmetiyonin ve S-adenozilhomosistin örüntüsü: Synonyms: S-adenozilmetiyonin ve S-adenozilhomosistin paterni |
| zh-CN | Chinese (China) | S-腺苷蛋氨酸与 S-腺苷同型胱氨酸模式: Synonyms: S 型 S-腺苷甲硫氨酸 S-腺苷蛋氨酸（S-腺苷甲硫氨酸）与 S-腺苷同型胱氨酸（S-高胱氨酸）模式（模式特征、 |