Version 2.80

Term Description

This assay detects antibodies against Leishmania donovani IgM for L. infantum screening based on the known cross reactivity between L. donovani and L. infantum. If the Leishmania IIFT is positive, a monospecific test (example Westernblot) can be performed to differentiate the pathogenic agents and confirm the diagnosis. Immunoglobulin specific slides distinguish between IgG, IgM and IgA. No reaction at a 1:100 titer indicates no IgM class antibodies against Leishmania donovani are detected, but infection cannot be excluded. A reaction of a titer at 1:100 is positive indicating a former or acute infection. This term was created for, but not limited in use to, the submitter's Euroimmun Anti-Leishmania donovani indirect immunofluorescence test kit.

Part Description

LP201795-4   Leishmania infantum+donovani
Leishmaniasis is a vector-borne disease transmitted by sandflies and caused by intracellular protozoa of the genus Leishmania. Human infection is caused by about 21 of 30 species that infect mammals, including the L. donovani complex with 3 species (L. donovani, L. infantum, and L. chagasi); the L. mexicana complex with 3 main species (L. mexicana, L. amazonensis, and L. venezuelensis); L. tropica; L. major; L. aethiopica; and the subgenus Viannia with 4 main species (L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) panamensis, and L. (V.) peruviana). The different species are morphologically indistinguishable, but they can be distinguished by isoenzyme analysis, molecular methods, or monoclonal antibodies. Leishmaniasis is found in about 88 countries, most in the tropics and subtropics. More than 90 percent of the world's cases of visceral leishmaniasis are in India, Bangladesh, Nepal, Sudan, and Brazil. Leishmaniasis is also found in Mexico, Central America, and South America, from northern Argentina to Texas (not in Uruguay, Chile, or Canada), southern Europe, Asia (not Southeast Asia), the Middle East, and Africa. Human Leishmaniasis comprises multiple clinical syndromes; visceral, cutaneous, and mucosal forms. Infections can result in two main forms of disease, cutaneous leishmaniasis and visceral leishmaniasis (kala-azar). Different species can be associated with diverse clinical manifestations and sequelae. Species identification can facilitate clinical management. Cutaneous leishmaniasis is characterized by cutaneous lesions. Visceral leishmaniasis presents with fever, weight loss, and an enlarged spleen and liver. Visceral leishmaniasis is becoming an important opportunistic infection in regions where it coexists with HIV. Source: Centers for Disease Control and Prevention , CDC: Leishmaniasis

Fully-Specified Name

Component
Leishmania infantum+donovani Ab.IgM
Property
Titr
Time
Pt
System
Ser/Plas
Scale
SemiQn
Method
IF

Additional Names

Long Common Name
Leishmania infantum+donovani IgM Ab [Titer] in Serum or Plasma by Immunofluorescence
Short Name
L infantum+donovani IgM Titr SerPl IF
Display Name
L. infantum+donovani IgM IF [Titer]
Consumer Name Alpha Get Info
Leishmania infantum+donovani IgM antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Πρωτόζωο Leishmania infantum+donovani (Λεϊσμάνια) Αντισώματα IgM:Titr:Pt:Ορός/Πλάσμα:Ημιποσοτική:Ανοσοφθορισμός
Synonyms: Titr Ανοσοσφαιρίνη M Πρωτόζωο Leishmania infantum+donovani (Λεϊσμάνια)
es-ES Spanish (Spain) Leishmania infantum+donovani IgM:Titulo / Factor de dilución:Punto temporal:Suero o Plasma:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Leishmania infantum + donovani Ab.IgM:Título:Punto temporal:Suero o Plasma:Cuantitativo:Inmunofluorescencia (IF)
fr-FR French (France) Leishmania infantum+Leishmania donovani Ac IgM:Titre:Ponctuel:Sérum/Plasma:Semi-Quantitatif:Immunofluorescence
it-IT Italian (Italy) Leishmania infantum+donovani Ab.IgM:Titr:Pt:Siero/Plasma:SemiQn:IF
Synonyms: Anticorpi IgM anticorpo Immunofluorescenza (IF) Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Titolo
nl-NL Dutch (Netherlands) Leishmania infantum + donovani As.IgM:titer:moment:serum of plasma:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF
pl-PL Polish (Poland) Leishmania infantum+donovani Ab.IgM:miano:punkt w czasie:surowica lub osocze:półilościowy:immunofluorescencja
Synonyms: IgM Leishmania infantum Leishmania infantum+donovani Przeciwciała do Leishmania infantum i donovani Przeciwciała IgM do Leishmania infantum i donovani
zh-CN Chinese (China) 婴儿利什曼原虫+杜氏利什曼原虫 抗体.IgM:滴定度:时间点:血清/血浆:半定量型:免疫荧光法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 免疫球蛋白 M 内脏利什曼病 利什曼原虫属 利什曼原虫病 利什曼病 利什曼虫 利什曼虫属 利什曼虫病 婴儿利什曼原虫（婴儿莱什曼原虫、婴儿利什曼虫）+杜氏利什曼原虫（利杜体、杜氏利什曼原虫无鞭毛体、杜氏莱什曼原虫、杜氏莱什曼虫） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 血清或血浆 黑热病

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80207-4