80381-7
Influenza virus A and B Ag panel - Upper respiratory specimen by Rapid immunoassay
Active
80382-5 Influenza virus A Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
Term Description
This term was created for, but is not limited in use to, the Influenza A part of the bioMerieux bioNexia Influenza A+B test, which is intended for the qualitative detection and differentiation of Influenza type A and type B antigens in human nasopharyngeal samples. The results of the bioNexia assay should be read ten minutes after the sample is applied to the sample well.
Source: Regenstrief LOINC
Part Descriptions
LP14239-5 Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock)
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus A Ag
- Property
- PrThr
- Time
- Pt
- System
- Respiratory system specimen.upper
- Scale
- Ord
- Method
- IA.rapid
Additional Names
- Short Name
- FLUAV Ag Upper resp Ql IA.rapid
- Display Name
- FLUAV Ag IA.rapid Ql (Upper resp)
- Consumer Name Alpha Get Info
- Influenza A (Flu A) antigen, Upper respiratory
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.77
- Change Reason
- Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC; Release 2.70: SYSTEM: Updated from "Nph" to make the LOINC term consistent with the original intent to represent a manufacturer's test covering NPH washes and nose swabs, as well as to make it consistent across panel usage.; Previous Releases: Corrected System from "Nasopharynx", which is used for LOINC clinical terms, to "Nph", which is the form used for LOINC lab terms.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1303
Example Answer List LL744-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80381-7 | Influenza virus A and B Ag panel - Upper respiratory specimen by Rapid immunoassay |
| 97099-6 | Influenza virus A and B and SARS-CoV-2 (COVID-19) Ag panel - Upper respiratory specimen by Rapid immunoassay |
| 95942-9 | Influenza virus A and B and SARS-CoV+SARS-CoV-2 (COVID-19) Ag panel - Upper respiratory specimen by Rapid immunoassay |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32757-3 | Influenza virus |
| LG34020-4 | Influenza virus A Ag| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Influenza-Virus A Ag: |
| es-MX | Spanish (Mexico) | Virus de la influenza A Ag: |
| es-ES | Spanish (Spain) | Virus Influenza A Antígeno: Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio |
| fr-FR | French (France) | Influenza virus A Ag: |
| it-IT | Italian (Italy) | Influenza A, virus, Ag: Synonyms: Campione da Apparato Respiratorio Campione da apparato respiratorio superiore Immunoassay Immunoassay rapido Microbiologia Presenza o Soglia Punto nel tempo (episodio) Virus dell''influenza Virus dell''influenza A |
| nl-NL | Dutch (Netherlands) | Influenzavirus A Ag: Synonyms: antigeen bovenste ademhalingsstelsel; |
80383-3 Influenza virus B Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
Term Description
This term was created for, but is not limited in use to, the Influenza B part of the bioMerieux bioNexia Influenza A+B test, which is intended for the qualitative detection and differentiation of Influenza type A and type B antigens in human nasopharyngeal samples. The results of the bioNexia assay should be read ten minutes after the sample is applied to the sample well.
Source: Regenstrief LOINC
Part Descriptions
LP14240-3 Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus B Ag
- Property
- PrThr
- Time
- Pt
- System
- Respiratory system specimen.upper
- Scale
- Ord
- Method
- IA.rapid
Additional Names
- Short Name
- FLUBV Ag Upper resp Ql IA.rapid
- Display Name
- FLUBV Ag IA.rapid Ql (Upper resp)
- Consumer Name Alpha Get Info
- Influenza B (Flu B) antigen, Upper respiratory
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.77
- Change Reason
- Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC; Release 2.70: SYSTEM: Updated from "Nph" to make the LOINC term consistent with the original intent to represent a manufacturer's test covering NPH washes and nose swabs, as well as to make it consistent across panel usage.; Previous Releases: Corrected System from "Nasopharynx", which is used for LOINC clinical terms, to "Nph", which is the form used for LOINC lab terms.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1305
Example Answer List LL744-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80381-7 | Influenza virus A and B Ag panel - Upper respiratory specimen by Rapid immunoassay |
| 97099-6 | Influenza virus A and B and SARS-CoV-2 (COVID-19) Ag panel - Upper respiratory specimen by Rapid immunoassay |
| 95942-9 | Influenza virus A and B and SARS-CoV+SARS-CoV-2 (COVID-19) Ag panel - Upper respiratory specimen by Rapid immunoassay |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32757-3 | Influenza virus |
| LG34023-8 | Influenza virus B Ag| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Influenza-Virus B Ag: |
| es-MX | Spanish (Mexico) | Virus de la influenza B Ag: |
| es-ES | Spanish (Spain) | Virus Influenza B Antígeno: Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio |
| fr-FR | French (France) | Influenza virus B Ag: |
| it-IT | Italian (Italy) | Influenza B, virus, Ag: Synonyms: Campione da Apparato Respiratorio Campione da apparato respiratorio superiore Immunoassay Immunoassay rapido Microbiologia Presenza o Soglia Punto nel tempo (episodio) Virus dell''influenza Virus dell''influenza B |
| nl-NL | Dutch (Netherlands) | Influenzavirus B Ag: Synonyms: antigeen bovenste ademhalingsstelsel; |