Version 2.77

Term Description

This nephelometric assay provides a sensitive test for monitoring patients with monoclonal light chain diseases but no M-spike on protein electrophoresis, and may be more sensitive than immunofixation for detection of monoclonal free light chains. In some patients with non-secretory myeloma, systemic amyloidosis, or light chain deposition disease, the nephelometric free light chain assay provides a positive identification of a monoclonal serum light chain when the serum immunofixation is negative.
Source: Regenstrief LOINC

Part Description

LP29081-4   Immunoglobulin light chains.kappa.free
Healthy patients have the majority of light chains in serum bound to heavy chains. Low levels of free light chains (unbound) are normal due to the over-production and secretion of free light chains by plasma cells. In the kidneys, the free light chains are selectively reabsorbed by the tubular cells, so their presence in urine is likely due to secretion into the urinary tract. Elevation of monoclonal free light chains in serum or urine signal malignant plasma cell proliferation (multiple myeloma), primary amyloidosis, or light chain deposition disease. Elevation of polyclonal free light chains suggests autoimmune diseases such as systemic lupus erythematosus. (Information from Freelite Beckman Coulter IMMAGE II package insert, Version 23, Feb 2009) Source: Regenstrief Institute

Fully-Specified Name

Component
Immunoglobulin light chains.kappa.free
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method
Nephelometry

Additional Names

Short Name
Kappa LC Free Ser Neph-mCnc
Display Name
Immunoglobulin light chains.kappa.free Nephelometry (S) [Mass/Vol]
Consumer Name Alpha Get Info
Free kappa light chains, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.73
Change Reason
Changed the LCN from 'Immunoglobulin light chains.kappa.free' to ' Kappa light chains.free' for readability.
Order vs. Observation
Both
Common Test Rank Get Info
18398

Member of these Panels

LOINC Long Common Name
81632-2 Immunoglobulin light chains.free panel - Serum by Nephelometry

Member of these Groups Get Info

LOINC Group Group Name
LG14797-1 Immunoglobulin light chains.kappa.free|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Immunglobulin-Leichtketten.kappa.frei:Massenkonzentration:Zeitpunkt:Serum:Quantitativ:Nephelometrie
es-ES Spanish (Spain) Cadenas ligeras kappa libres:Concentración de masa:Punto temporal:Suero:Qn:Nefelometría
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cadenas ligeras de inmunoglobulina kappa.libre:Concentración de masa:Punto temporal:Suero:Cuantitativo:Nefelometría
et-EE Estonian (Estonia) Immuunglobuliinide kerged kapaahelad:MCnc:Pt:S:Qn:Nefelomeetria
Synonyms: Immuunglobuliinide kerged kapaahelad Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Chaîne légère des immunoglobulines.kappa.libre:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:Néphélométrie
fr-FR French (France) Immunoglobuline chaines légères libres kappa:Masse/Volume:Ponctuel:Sérum:Numérique:Néphélémétrie
fr-BE French (Belgium) Chaîne légère des immunoglobulines.kappa.libre:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:Néphélométrie
Synonyms: FLC.kappa.libre, FLC.kappa LC LC. Kappa
it-IT Italian (Italy) Immunoglobuline, catene leggere.kappa.libere:MCnc:Pt:Siero:Qn:Nefelometria
Synonyms: Catene leggere delle immunoglobuline Catene leggere kappa delle immunoglobuline Catene leggere kappa libere delle immunoglobuline Chimica Concentrazione di Massa Nefelometria Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) immunoglobuline lichte ketens.kappa.vrij:massa/volume:moment:serum:kwantitatief:nefelometrie
Synonyms: nefelometrische methode
pl-PL Polish (Poland) Łańcuchy lekkie immunoglobulin.kappa.wolne:stężenie masowe:punkt w czasie:surowica:ilościowy:nefelometria
Synonyms: Łańcuchy lekkie immunoglobulin Łańcuchy lekkie kappa immunoglobuliny Łańcuchy lekkie wolne kappa
ru-RU Russian (Russian Federation) Иммуноглобулин легкие цепи.каппа.свободные:МассКонц:ТчкВрм:Сыв:Колич:Нефелометрия
Synonyms: Количественный Массовая концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) İmmünglobulin hafif zincirler.kappa.serb:KütlKons:Zmlı:Ser:Kant:Nefelometri
zh-CN Chinese (China) 免疫球蛋白轻链.Kappa 型.游离型:质量浓度:时间点:血清:定量型:浊度分析法
Synonyms: Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白（Bence Jones protein，BJ Protein，BJP）;本周蛋白;本-周蛋白 Ig Kappa LC;Kappa 型免疫球蛋白轻链;Kappa 型轻链;Kappa 轻链;κ型免疫球蛋白轻链;κ型轻链;κ轻链;免疫球蛋白轻链.Kappa;免疫球蛋白轻链.κ型;轻链.Kappa;轻链.Kappa 型;轻链.κ;轻链.κ型 丙种球蛋白 依靠测定散射光的分析方法;光散射;比浊;比浊法;浊度分析;浊度测定;浊度测定法 免疫球蛋白（Immunoglobulin，Ig） 免疫球蛋白类 免疫球蛋白轻链.Kappa 型.游离;免疫球蛋白轻链.Kappa.游离;免疫球蛋白轻链.Kappa.游离型;免疫球蛋白轻链.κ型.游离;免疫球蛋白轻链.κ型.游离型;游离 Kappa LC;游离 Kappa 型免疫球蛋白轻链;游离 Kappa 型轻链;游离 Kappa 轻链;游离κ型免疫球蛋白轻链;游离κ型轻链;游离κ轻链;游离型 Kappa LC;游离型 Kappa 免疫球蛋白轻链;游离型 Kappa 型免疫球蛋白轻链;游离型 Kappa 型轻链;游离型 Kappa 轻链;游离型κ免疫球蛋白轻链;游离型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 游离 链 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
mg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80515-0