80516-8

Lambda light chains.free [Mass/volume] in Serum by Nephelometry

Active

Term Description

This nephelometric assay provides a sensitive test for monitoring patients with monoclonal light chain diseases but no M-spike on protein electrophoresis, and may be more sensitive than immunofixation for detection of monoclonal free light chains. In some patients with non-secretory myeloma, systemic amyloidosis, or light chain deposition disease, the nephelometric free light chain assay provides a positive identification of a monoclonal serum light chain when the serum immunofixation is negative.

Part Description

LP29082-2 Immunoglobulin light chains.lambda.free
Healthy patients have the majority of light chains in serum bound to heavy chains. Low levels of free light chains (unbound) are normal due to the over-production and secretion of free light chains by plasma cells. In the kidneys, the free light chains are selectively reabsorbed by the tubular cells, so their presence in urine is likely due to secretion into the urinary tract. Elevation of monoclonal free light chains in serum or urine signal malignant plasma cell proliferation (multiple myeloma), primary amyloidosis, or light chain deposition disease. Elevation of polyclonal free light chains suggests autoimmune diseases such as systemic lupus erythematosus. (Information from Freelite Beckman Coulter IMMAGE II package insert, Version 23, Feb 2009) Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name: Immunoglobulin light chains.lambda.free:MCnc:Pt:Ser:Qn:Nephelometry
Long Common Name: Lambda light chains.free [Mass/volume] in Serum by Nephelometry
Short Name: Lambda LC Free Ser Neph-mCnc
Display Name: Immunoglobulin light chains.lambda.free Nephelometry (S) [Mass/Vol]
Consumer Name Alpha Get Info: Free lambda light chains, Blood

Part Model Get Info

Component
Immunoglobulin light chains.lambda.free
LP29082-2
- Analyte
  Immunoglobulin light chains.lambda.free
  LP29082-2
  - Component Numerator
    Immunoglobulin light chains.lambda.free
    LP29082-2
    - Component Numerator Core
      Immunoglobulin light chains.lambda.free
      LP29082-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Nephelometry
LP6415-6

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.73 (MIN)
Change Reason: Changed the LCN from 'Immunoglobulin light chains.lambda.free' to ' Lambda light chains.free' for readability
Order vs. Observation: Both
Common Test Rank Get Info: 19254

Member of these Panels

LOINC	Long Common Name
81632-2	Immunoglobulin light chains.free panel - Serum by Nephelometry

Member of these Groups Get Info

LOINC Group	Group Name
LG14589-2	Immunoglobulin light chains.lambda.free\|MCnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Ig lehké řetězce lambda.volné:Hmotnostní koncentrace:Časový bod:Sérum:Kvantitativní:Nefelometrie
el-GR	Greek (Greece)	Ελαφρές αλυσίδες ανοσοσφαιρίνης.λάμδα.ελεύθερες:MCnc:Pt:Ορός:Qn:Νεφελομετρία Synonyms: CHEM MCnc Pt Qn Ελαφρές αλυσίδες ανοσοσφαιρίνης Ελαφρές αλυσίδες ανοσοσφαιρίνης.λάμδα.ελεύθερες Ελαφριές αλυσίδες ανοσοσφαιρίνης.λάμδα Νεφελομετρία Ορός
es-ES	Spanish (Spain)	Cadenas ligeras lambda libres:Concentración de masa:Punto temporal:Suero:Qn:Nefelometría Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cadenas ligeras de inmunoglobulina lambda.libre:Concentración de masa:Punto temporal:Suero:Cuantitativo:Nefelometría
et-EE	Estonian (Estonia)	Immuunglobuliinide kerged lambdaahelad:MCnc:Pt:S:Qn:Nefelomeetria Synonyms: Immuunglobuliinide kerged lambdaahelad Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Chaînes légères des immunoglobulines.lambda.libre:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:Néphélométrie
fr-FR	French (France)	Immunoglobuline chaines légères libres lambda:Masse/Volume:Ponctuel:Sérum:Numérique:Néphélémétrie
fr-BE	French (Belgium)	Chaînes légères des immunoglobulines.lambda.libre:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:Néphélométrie Synonyms: FLC.lambda.libre, FLC.lambda LC LC. Lambda
it-IT	Italian (Italy)	Immunoglobuline, catene leggere.lambda.libere:MCnc:Pt:Siero:Qn:Nefelometria Synonyms: Catene leggere delle immunoglobuline Catene leggere lambda delle immunoglobuline Catene leggere lambda libere delle immunoglobuline Chimica Concentrazione di Massa Nefelometria Punto nel tempo (episodio) Siero
nl-NL	Dutch (Netherlands)	immunoglobuline lichte ketens.lambda.vrij:massa/volume:moment:serum:kwantitatief:nefelometrie Synonyms: nefelometrische methode
pl-PL	Polish (Poland)	Łańcuchy lekkie immunoglobulin.lambda.wolne:stężenie masowe:punkt w czasie:surowica:ilościowy:nefelometria Synonyms: Łańcuchy lekkie immunoglobulin Łańcuchy lekkie lambda immunoglobuliny Łańcuchy lekkie wolne lambda
ru-RU	Russian (Russian Federation)	Иммуноглобулин легкие цепи.лямбда.свободная:МассКонц:ТчкВрм:Сыв:Колич:Нефелометрия Synonyms: Количественный Массовая концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	İmmünglobulin hafif zincirler.lambda.serb:KütlKons:Zmlı:Ser:Kant:Nefelometri
zh-CN	Chinese (China)	免疫球蛋白轻链.Lambda 型.游离型:质量浓度:时间点:血清:定量型:浊度分析法 Synonyms: Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白（Bence Jones protein，BJ Protein，BJP）;本周蛋白;本-周蛋白 Ig Lambda LC;Lambda 型免疫球蛋白轻链;Lambda 型轻链;Lambda 轻链;λ型免疫球蛋白轻链;λ型轻链;λ轻链;免疫球蛋白轻链.Lambda;免疫球蛋白轻链.λ型;轻链.Lambda;轻链.Lambda 型;轻链.λ;轻链.λ型丙种球蛋白依靠测定散射光的分析方法;光散射;比浊;比浊法;浊度分析;浊度测定;浊度测定法免疫球蛋白（Immunoglobulin，Ig）免疫球蛋白类免疫球蛋白轻链.Lambda 型.游离;免疫球蛋白轻链.Lambda.游离;免疫球蛋白轻链.Lambda.游离型;免疫球蛋白轻链.λ型.游离;免疫球蛋白轻链.λ型.游离型;游离 Lambda LC;游离 Lambda 型免疫球蛋白轻链;游离 Lambda 型轻链;游离 Lambda 轻链;游离λ型免疫球蛋白轻链;游离λ型轻链;游离λ轻链;游离型 Lambda LC;游离型 Lambda 免疫球蛋白轻链;游离型 Lambda 型免疫球蛋白轻链;游离型 Lambda 型轻链;游离型 Lambda 轻链;游离型化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 游离链非蛋白结合型非蛋白质结合型

Example Units

Unit	Source
mg/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.