Version 2.77

Term Description

The presence of gastric pepsin A in a patient's airway is a marker for aspiration and assists in the diagnosis of gastroesophageal reflux. Chronic aspiration of gastric contents may worsen lung disease in premature infants, or other mechanically ventilated patients. PMID: 16954956 This assay detects both pepsin A and pepsinogen A and does not differentiate between the two. A level of less than 3 is considered in range. (One unit of pepsin A=0.1ng/ml pepsin A is a measure of concentration (ng/ml) expressed in an arbitrarily defined unit.)
Source: Regenstrief LOINC

Part Description

LP206550-8   Pepsin A+Pepsinogen A
Pepsin is the principal proteolytic enzyme of vertebrate gastric juice. Pepsin's inactive precursor form, pepsinogen, is produced in stomach mucosa. The minor pepsins are designated "B", "C", and "D". "A" is the major component. Source: Regenstrief LOINC, Pepsin

Fully-Specified Name

Component
Pepsin A+Pepsinogen A
Property
MCnc
Time
Pt
System
Respiratory system specimen.lower
Scale
Qn
Method
IA

Additional Names

Short Name
PepsinA+PepsinogenA Lower resp IA-mCnc
Display Name
Pepsin A+Pepsinogen A IA (Lower resp) [Mass/Vol]
Consumer Name Alpha Get Info
Pepsin A+Pepsinogen A, Lower respiratory

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.77
Change Reason
Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
80831-1 Pepsin A Panel - Lower respiratory specimen

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Pepsin /SM
es-MX Spanish (Mexico) Pepsina A + Pepsinógeno A:Concentración de masa:Punto temporal:Muestra de vías respiratorias inferiores:Cuantitativo:Inmunoensayo
fr-FR French (France) Pepsine A+pepsinogène A:Masse/Volume:Ponctuel:Voies respiratoires inférieures:Numérique:Immunoanalyse
nl-NL Dutch (Netherlands) pepsine A + pepsinogeen A:massa/volume:moment:onderste luchtwegen:kwantitatief:immunoassay
Synonyms: IA onderste ademhalingsstelsel; systema respiratorium inferior systema respiratorium; ademhalingsstelsel

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80828-7