Version 2.80

Part Descriptions

LP206570-6   Tobramycin.free
Tobramycin sulfate is an aminoglycoside antibiotic produced by Streptomyces tenebrarius used to treat various bacterial infections, particularly Gram-negative infections. It works by binding to a site on the bacterial ribosome, causing the genetic code to be misread. Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or intramuscularly. This formulation for injection is branded Nebcin®. Patients with cystic fibrosis will often take an inhalational form (Tobi®) for suppression of Pseudomonas aeruginosa infections. Tobramycin is also combined with dexamethasone as an ophthalmic solution (TobraDex®). Bausch Lomb Pharmaceuticals, Inc. makes a sterile Tobramycin Ophthalmic Solution (eye-drops) with a tobramycin concentration of 0.3%. In the USA it is available by prescription only. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Tobramycin (Wikipedia)

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
Tobramycin.free
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Tobramycin free [Mass/volume] in Serum or Plasma
Short Name
Tobramycin free SerPl-mCnc
Display Name
Tobramycin free [Mass/Vol]
Consumer Name Alpha Get Info
Free tobramycin, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.56 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Τομπραμυκίνη.ελεύθερη:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: MCnc Τομπραμυκίνη Τομπραμυκίνη.ελεύθερη
es-ES Spanish (Spain) Tobramicina libre:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Tobramicina libre:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) Tobramycine libre:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Tobramicina.libera:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Tobramicina libera
nl-NL Dutch (Netherlands) tobramycine.vrij:massa/volume:moment:serum of plasma:kwantitatief:
zh-CN Chinese (China) 妥布霉素.游离型:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 妥布拉霉素;托普霉素;托布拉霉素 妥布霉素（妥布拉霉素、托普霉素、托布拉霉素）.游离型;游离型（游离）妥布霉素（妥布拉霉素、托普霉素、托布拉霉素） 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 游离 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
mg/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80966-5