81308-9
Influenza virus A RNA [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection
Active
Part Description
LP14239-5 Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock)
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus A RNA
- Property
- ThreshNum
- Time
- Pt
- System
- Respiratory System Specimen
- Scale
- Qn
- Method
- Probe.amp.tar
Additional Names
- Short Name
- FLUAV RNA Ct Resp Qn NAA+probe
- Display Name
- FLUAV RNA NAA+probe (Respiratory system specimen) [ThreshNum]
- Consumer Name Alpha Get Info
- Influenza A (Flu A), Respiratory system specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.75
- Change Reason
- Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 81233-9 | Influenza virus types A and B and subtypes RNA panel - Respiratory system specimen by NAA with probe detection |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32757-3 | Influenza virus |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Influenza-Virus A RNA: |
| es-ES | Spanish (Spain) | Virus Influenza A RNA: Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio |
| es-MX | Spanish (Mexico) | ARN del virus de la influenza A: |
| fr-FR | French (France) | Influenza virus A ARN: |
| it-IT | Italian (Italy) | Influenza A, virus RNA: Synonyms: Campione da Apparato Respiratorio Limite di soglia Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A |
| nl-NL | Dutch (Netherlands) | Influenzavirus A RNA: Synonyms: probe.amp.tar systema respiratorium; |
| zh-CN | Chinese (China) | 流感病毒 A 型 RNA: Synonyms: A 型 A 型流感; |
Example Units
| Unit | Source |
|---|---|
| {Ct_value} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=81308-9
LOINC Copyright
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