Version 2.78

Term Description

Human RNase P is used as an internal control with human clinical specimens to confirm that nucleic acid was adequately extracted from. Possible specimens include: upper respiratory tract clinical specimens (including nasopharyngeal swabs, nasal swabs, throat swabs, nasal aspirates, nasal washes, and dual nasopharyngeal/throat swabs), and lower respiratory tract specimens (including bronchoalveolar lavage, bronchial wash, tracheal aspirate, sputum, and lung tissue.
Source: Regenstrief LOINC

Part Description

LP135667-6   Human RNase P
Ribonuclease P (EC 3.1.26.5, RNase P) is a type of ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme - a ribonucleic acid that acts as a catalyst in the same way that a protein based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Further, RNase P is one of two known multiple turnover ribozymes in nature (the other being the ribosome), the discovery of which earned Sidney Altman and Thomas Cech the Nobel Prize in Chemistry in 1989: in the 1970s, Altman discovered the existence of precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA. Recent findings also reveal that RNase P has a new function. It has been shown that human nuclear RNase P is required for the normal and efficient transcription of various small noncoding RNAs, such as tRNA, 5S rRNA, SRP RNA and U6 snRNA genes., which are transcribed by RNA polymerase III, one of three major nuclear RNA polymerases in human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Human RNase P RNA
Property
ThreshNum
Time
Pt
System
Respiratory System Specimen
Scale
Qn
Method
Probe.amp.tar

Additional Names

Short Name
Human RNase P RNA Ct Resp Qn NAA+probe
Display Name
Human RNase P RNA NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info
Human RNase P, Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
81233-9 Influenza virus types A and B and subtypes RNA panel - Respiratory system specimen by NAA with probe detection

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Rnase P humana RNA:ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX Spanish (Mexico) ARN Rnasa P humana:ThreshNum:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Ribonucléase P ARN:Cycle seuil:Ponctuel:Échantillon du système respiratoire:Numérique:PCR amplification de cible
it-IT Italian (Italy) Rnasi P umana RNA:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Limite di soglia Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Humaan Rnase P RNA:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie
Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) 人核糖核酸酶 P RNA:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向
Synonyms: P 型 人核酶 P;人 RNA P 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 核糖核酸;Ribonucleic acid 界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值 经过扩增的 脱氧核糖核酸探针 试样

Example Units

Unit Source
{Ct_value} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81326-1