82474-8
Borrelia mayonii oppA1 gene [Presence] in Specimen by NAA with non-probe detection
Active
Term Description
The DNA amplification target is the 283-bp plasminogen-binding protein gene (oppA1), which is present at a frequency of one copy per organism in all four pathogenic species of the Borrelia burgdorferi sensu lato genogroup (Borrelia burgdorferi sensu stricto, Borrelia afzelii, Borrelia garinii, and Borrelia mayonii). Melting curve analysis is used to identify B. mayonii and differentiate it from the other three species. Potential specimens include CSF, tissue and synovial fluid.
Source: Regenstrief LOINC
Part Descriptions
LP220481-8 Borrelia mayonii oppA1 gene
Borrelia mayonii is the proposed name for a bacterial species found in 2013, causing Lyme disease in six people who live in the upper Midwestern United States. Worldwide, Lyme disease is caused by three main species of bacteria: Borrelia burgdorferi, B. afzelii, and B. garinii. Borrelia burgdorferi causes Lyme disease in the United States, while the other two species are the leading causes of Lyme disease in Europe and Asia. B. mayonii is a new species that is genetically distinct from these three species and is the only species besides B. burgdorferi shown to cause Lyme disease in North America. B. mayonii has been identified in blacklegged (or "deer") ticks collected in several counties in northwestern Wisconsin and Minnesota. It is highly likely, however, that infected ticks occur in other areas of both states. Limited information suggests that illness caused by B. mayonii is similar to that caused by B. burgdorferi, but with a few possible differences. Like B. burgdorferi, B. mayonii causes fever, headache, rash, and neck pain in the early stages of infection (days after exposure) and arthritis in later stages of infection (weeks after exposure). Unlike B. burgdorferi however, B. mayonii appears to be associated with nausea and vomiting, diffuse rashes, and a higher concentration of bacteria in the blood. Patients infected with B. mayonii have been successfully treated with a 2-4 week course of doxycycline. Amoxicillin, ceftriaxone, and cefuroxime have also been used.
Source: Centers for Disease Control and Prevention, CDC: Borrelia mayonii
LP220481-8 Borrelia mayonii oppA1 gene
The oppA1 gene is a member of a family of three genes; oppA-1, oppA-2, and oppA-3, that encode predicted peptide-binding proteins. Peptide-binding protein dependent transport systems are recognized to play important roles in microbial cell signaling and virulence. PMID: 9712756
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Borrelia mayonii oppA1 gene
- Property
- PrThr
- Time
- Pt
- System
- XXX
- Scale
- Ord
- Method
- Non-probe.amp.tar
Additional Names
- Short Name
- B mayonii oppA1 Spec Ql NAA+non-probe
- Display Name
- B. mayonii oppA1 gene NAA+non-probe Ql (Specimen)
- Consumer Name Alpha Get Info
- Borrelia mayonii oppA1 gene, Specimen
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.69
- Change Reason
- Release 2.68: COMPONENT: Removed parentheses from Component for consistency and accuracy.; Previous Releases:
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG41633-5 | Borrelia |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gen oppA1 de Borrelia mayonii: |
es-MX | Spanish (Mexico) | Gen oppA1 de Borrelia mayonii: |
fr-FR | French (France) | Borrelia mayonii oppA1 gène: |
it-IT | Italian (Italy) | Borrelia mayonii (oppA1), gene: Synonyms: Amplificazione target non basata su sonda Gene Borrelia mayonii (oppA1) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
zh-CN | Chinese (China) | 梅奥疏螺旋体 oppA1 基因: Synonyms: 不明的; |
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- CodeSystem lookup
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Third Party Copyright
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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright