Version 2.78

Term Description

The DNA amplification target is a gene encoding glycerophosphodiester phosphodiesterase (GlpQ), which is specific to the Borrelia species in the relapsing fever group. This gene is not found in the Borrelia species that cause Lyme disease. Melting curve analysis is then used to identify the B. miyamotoi organism. A positive result is consistent with active or recent infection. B. miyamotoi infections of the central nervous system are associated with the symptoms and signs of meningoencephalitis.
Source: Regenstrief LOINC

Part Description

LP221168-0   Borrelia miyamotoi glpQ gene
Borrelia miyamotoi is a spirochetal bacterium that is closely related to the Borrelia species that causes tick-borne relapsing fever (TBRF), and it is more distantly related to the Borrelia species that cause Lyme disease. First identified in 1995 in ticks from Japan, B. miyamotoi has since been detected in two species of North American ticks, the black-legged or "deer" tick (Ixodes scapularis) and the western black-legged tick (Ixodes pacificus). These ticks are already known to transmit several diseases, including Lyme disease, anaplasmosis, and babesiosis. Patients with B. miyamotoi infection are most likely to have fever, chills, and headache. Other common symptoms included body and joint pain and fatigue. Unlike Lyme disease, rash is uncommon, presenting in only 4 out of 51 patients. Patients infected with B. miyamotoi have been treated with a 2-4 week course of doxycycline, amoxicillin, or ceftriaxone. Fewer than 60 well-documented cases of human infection have been reported in the United States as of July 2015. The route of transmission of B. miyamotoi to humans has not been firmly established, but likely involves the bite of infected black-legged ticks. The glpQ gene encodes a periplasmic enzyme, glycerophosphodiester phosphodiesterase of 333 amino acids produced initially with a 25 residue long signal sequence. GlpQ is not found in Borrelia species that cause Lyme disease. Source: Regenstrief LOINC, CDC: B. miyamotoi

Fully-Specified Name

Component
Borrelia miyamotoi glpQ gene
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
Non-probe.amp.tar

Additional Names

Long Common Name
Borrelia miyamotoi glpQ gene [Presence] in Cerebral spinal fluid by NAA with non-probe detection
Short Name
B miyamotoi glpQ CSF Ql NAA+non-probe
Display Name
B. miyamotoi glpQ gene NAA+non-probe Ql (CSF)
Consumer Name Alpha Get Info
Borrelia miyamotoi glpQ gene, Spinal fluid

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.68
Change Reason
Release 2.68: COMPONENT: Removed parentheses around the bacterial gene name based on current LONC naming model.; Previous Releases:
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG41633-5 Borrelia

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen glpQ de Borrelia miyatomoi:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda
es-MX Spanish (Mexico) Gen glpQ de Borrelia miyamotoi:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-FR French (France) Borrelia miyamotoi glpQ gène:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Non-PCR amplification de cible
it-IT Italian (Italy) Borrelia miyamotoi (glpQ), gene:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Gene Borrelia miyamotoi (glpQ) Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
zh-CN Chinese (China) 宫本疏螺旋体 glpQ 基因:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 米亚莫托疏螺旋体 glpQ 基因;宫本伯氏包柔螺旋体 glpQ 基因 米亚莫托疏螺旋体;宫本伯氏包柔螺旋体 经过扩增的 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 脱氧核糖核酸探针 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82476-3