Version 2.78

32286-7 Hepatitis C virus genotype [Identifier] in Serum or Plasma by NAA with probe detection

Part Descriptions

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Component
Hepatitis C virus genotype
Property
Prid
Time
Pt
System
Ser/Plas
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
HCV Gentyp SerPl NAA+probe
Display Name
HCV genotype NAA+probe
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) genotype, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.07
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
1655

Example Answer List LL2254-2

Answer Code Score Answer ID
1 LA6112-2
2 or more LA6113-0
3 LA6114-8
4 LA6115-5
5 LA10137-0
6 LA10138-8
Not detected LA11883-8

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: HCV Genotyp
de-DE German (Germany) Hepatitis-C-Virus Genotyp:Nachweis oder Identität:Zeitpunkt:Serum oder Plasma:Nominal:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepacivirus C; HCV
el-GR Greek (Greece) Ιός Ηπατίτιδας C γονότυπος:Παρουσία ή ταυτοποίηση:Χρονική στιγμή:Ορός/Πλάσμα:Ονομαστική:Ανιχνευτής με ενίσχυση στόχου
es-AR Spanish (Argentina) genotipo del virus de hepatitis C:tipo:punto en el tiempo:suero/plasma:Nominal:sonda.amplificación.blanco
es-ES Spanish (Spain) Virus Hepatitis C Genotipo:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Genotipo del virus de la hepatitis C:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Virus de l'hépatite C, Génotype:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Sonde avec amplification de la cible
fr-FR French (France) Hépatite C virus génotype:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:PCR amplification de cible
fr-BE French (Belgium) Virus de l'hépatite C Génotype:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Sonde avec amplification de la cible
Synonyms: Génotype HCV
it-IT Italian (Italy) Epatite C, virus, genotipo:Prid:Pt:Siero/Plasma:Nom:Sonda.amp.tar
Synonyms: Microbiologia Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite C
ko-KR Korean (Korea, Republic Of) C형 간염 바이러스 유전형:존재:검사시점:혈청/혈장:명칭결과:DNA 탐색자.증폭.표적
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype:identificator:moment:serum of plasma:nominaal:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Hepatite C vírus genotipagem:Ident:Pt:Sor/Plas:Nom:Sonda com limite de detecção da amplificação de alvo
Synonyms: ; HCV; Hep C; Identity or presence; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Nominal; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Gentyp; Amplified; Hepatit; Hepatis; Microbiology
ru-RU Russian (Russian Federation) Гепатита С вирус генотип:ПрИд:ТчкВрм:Сыв/Плаз:Ном:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Номинальный;Именной Плазма Присутствие или Идентификация Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit C virüsü genotip:MevcKimlik:Zmlı:Ser/Plaz:Snf:Prob.amf.hdf
uk-UA Ukrainian (Ukraine) Вірусу Гепатиту С генотип:Наявність або Ідентифікація:МоментЧасу:Сироватка/Плазма:Категорійно:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; DNA NUCLEIC ACID PROBE; DNA probe; Gentyp; HCV; Hep; Hep C; Hepatis; Hepatit; Hepatology; ID; Identity or presence; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Liver; Microbiology; NAA+probe; NAAT; NASBA; Nominal; Nucleic acid sequence based analysis; PCR; Pl; Plasma; Plsm; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; Random; SDA; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Strand Displacement Amplification; TMA; Transcription mediated amplification; UniversalLabOrders
zh-CN Chinese (China) 丙型肝炎病毒 基因型:存在与否或特征标识:时间点:血清/血浆:名义型:探针法.基因扩增.靶向
Synonyms: C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 属模标本;遗传型 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 肝 脱氧核糖核酸探针 血清或血浆

92731-9 Hepatitis C virus genotype in Serum or Plasma by Sequencing

Part Descriptions

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis C virus genotype
Property
Type
Time
Pt
System
Ser/Plas
Scale
Nom
Method
Sequencing

Additional Names

Short Name
HCV Gentyp SerPl Seq
Display Name
HCV genotype Sequencing
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) genotype, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.72
Order vs. Observation
Both

Preferred Answer List LL2254-2

Answer Code Score Answer ID
1 LA6112-2
2 or more LA6113-0
3 LA6114-8
4 LA6115-5
5 LA10137-0
6 LA10138-8
Not detected LA11883-8

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Genotyp:Typ:Zeitpunkt:Serum oder Plasma:Nominal:Sequenzierung
Synonyms: Hepacivirus C; HCV
es-ES Spanish (Spain) Virus Hepatitis C Genotipo:Tipo:Punto temporal:Suero o Plasma:Nom:Secuenciación
es-MX Spanish (Mexico) Genotipo del virus de la hepatitis C:Tipo:Punto temporal:Suero o Plasma:Nominal:Secuenciación
fr-BE French (Belgium) Virus de l'hépatite C Génotype:Type:Temps ponctuel:Sérum/Plasma:Nominal:Séquençage
Synonyms: Génotype HCV
fr-FR French (France) Hépatite C virus génotype:Type:Ponctuel:Sérum/Plasma:Résultat nominal:Séquençage
fr-CA French (Canada) Virus de l'hépatite C, Génotype:Type:Temps ponctuel:Sérum/Plasma:Nominal:Séquençage
it-IT Italian (Italy) Epatite C, virus, genotipo:Tipo:Pt:Siero/Plasma:Nom:Sequenziamento
Synonyms: Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype:type:moment:serum of plasma:nominaal:sequencing
pl-PL Polish (Poland) Wirus zapalenia wątroby typu C genotyp:typ:punkt w czasie:surowica lub osocze:cecha:sekwencjonowanie
Synonyms: Genotyp wirusa zapalenia wątroby typu C
tr-TR Turkish (Turkey) Hepatit C virüsü genotip:Tip:Zmlı:Ser/Plaz:Snf:Sekanslama
Synonyms: Dizi tayini Tür
zh-CN Chinese (China) 丙型肝炎病毒 基因型:类型:时间点:血清/血浆:名义型:序列测定
Synonyms: C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 型 属模标本;遗传型 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 肝 血清或血浆

82512-5 Hepatitis C virus genotype 1 [Type] in Serum or Plasma by NAA with probe detection

Term Description

This test is used to help optimize treatment selection for patients being considered for NS5A inhibitor therapy.
Source: Regenstrief LOINC

Part Descriptions

LP220402-4   Hepatitis C virus genotype 1
There are six major hepatitis C virus genotypes (1-6), each of which can be further subdivided into subtypes (for example, 1a, 1b, 2a). Genotypes 1, 2 and 3 are widely distributed in developed countries while other genotypes appear to be more geographically localized PMID: 10755999 Genotype 1 (including subtypes 1a and 1b) is the most prevalent by far in the United States. Genotype 3, constitutes 10% of HCV infections in the United States and Canada. Patients with this HCV genotype have a higher incidence of hepatocellular carcinoma, higher prevalence of steatosis and insulin resistance, and faster rates of fibrosis progression compared to patients with other HCV genotypes. Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis C virus genotype 1
Property
Type
Time
Pt
System
Ser/Plas
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
HCV Gentyp 1 SerPl NAA+probe
Display Name
HCV genotype 1 NAA+probe Nom
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) Genotype 1, Blood

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
19635

Example Answer List LL4038-7

Answer Code Score Answer ID
Not detected LA11883-8
1 LA6112-2
1A LA19241-1
1B LA19242-9

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Genotyp 1:Typ:Zeitpunkt:Serum oder Plasma:Nominal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Genotipo 1 del virus de la Hepatitis C:Tipo:Punto temporal:Suero o Plasma:Nom:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Genotipo 1 del virus de la hepatitis C:Tipo:Punto temporal:Suero o Plasma:Nominal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Hépatite C virus génotype 1:Type:Ponctuel:Sérum/Plasma:Résultat nominal:PCR amplification de cible
it-IT Italian (Italy) Epatite C virus, genotipo 1:Tipo:Pt:Siero/Plasma:Nom:Sonda.amp.tar
Synonyms: Genotipo 1 virus dell''epatite C Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype 1:type:moment:serum of plasma:nominaal:probe-detectie
Synonyms: probe.amp.tar
zh-CN Chinese (China) 丙型肝炎病毒基因型 1:类型:时间点:血清/血浆:名义型:探针法.基因扩增.靶向
Synonyms: Ⅰ C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 I 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 1 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 型 扩增型 扩增性 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 经过扩增的 肝 脱氧核糖核酸探针 血清或血浆

82380-7 Hepatitis C virus genotype 1 NS5a gene mutations detected [Identifier]

Term Description

The answer list contains two examples of NS5a gene identified mutations.
Source: Regenstrief LOINC

Part Descriptions

LP220245-7   Hepatitis C virus genotype 1 NS5a gene mutations detected
Hepatitis C virus nonstructural 5a (NS5a) is a phosphoprotein, involved both in viral replication and in many interactions with cellular signaling pathways, including the interferon anti-viral pathway. PMID: 26719254 The principal HCV NS5A mutations associated with resistance to the NS5A inhibitors include those identified at codons 28, 30, 31, 58, and 93. The identification of specific mutations or polymorphisms may be useful to optimize treatment selection. Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis C virus genotype 1 NS5a gene mutations detected
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method
Genotyping

Additional Names

Short Name
HCV Gentyp 1 NS5a Mut Det Islt
Display Name
HCV genotype 1 NS5a gene mutations detected Genotyping Nom (Isol)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) genotype 1 NS5a gene variant analysis

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
7184

Example Answer List LL4043-7

Answer Code Score Answer ID
None detected LA19544-8
Y93H LA26376-6
L31M LA26380-8

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Genotyp 1 NS5a-Gen Mutationen entdeckt:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:Genotypisierung
es-ES Spanish (Spain) Gen NS5a del genotipo 1 del virus de la Hepatitis C Detección de mutaciones:Presencia o identidad:Punto temporal:Aislado:Nom:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Se detectaron mutaciones en el gen NS5a del genotipo 1 del virus de la hepatitis C:Presencia o identidad:Punto temporal:Aislado:Nominal:Susceptibilidad del genotipo viral
fr-FR French (France) Hépatite C virus génotype 1 NS5a gène mutations détectées:Identification:Ponctuel:Isolat:Résultat nominal:Génotypage
it-IT Italian (Italy) Epatite C virus, genotipo 1 gene NS5a, mutazioni identificate:Prid:Pt:Isolato:Nom:Genotipizzazione
Synonyms: Gene NS5a genotipo 1 virus dell''epatite C Genotipo 1 virus dell''epatite C Presenza o Identità Punto nel tempo (episodio) Suscettibilità agli antibiotici Suscettibilità al genotipo virale Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype 1 NS5a gen gedetecteerde mutaties:identificator:moment:isolaat:nominaal:genotypering
pl-PL Polish (Poland) Gen NS5a HCV genotyp 1 wykryte mutacje:wykrycie lub identyfikacja:punkt w czasie:izolat:cecha:genotypowanie
Synonyms: Genotyp wirusa zapalenia wątroby typu C Wykryto mutacje genu NS5a wirusa zapalenia wątroby typu C genotypu 1
zh-CN Chinese (China) 丙型肝炎病毒基因型 1 NS5a 基因 已检出的突变:存在与否或特征标识:时间点:分离株:名义型:基因分型
Synonyms: Ⅰ C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 I 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 1 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 1 NS5a 基因 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 存在;存在与否;特征标识;身份;身份标识 已发现的突变 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 突变 突变类;基因突变 肝 遗传基因;遗传因子;吉恩;生物基因

82381-5 Hepatitis C virus genotype 1 NS5b gene mutations detected [Identifier]

Term Description

Detects mutations in the Hepatitis C genotype 1 BS5b gene that are associated with resistance to nucleotide analog NS5b polymerase inhibitors such as sofosbuvir. The answer list contains three examples of the NS5b gene mutations.
Source: Regenstrief LOINC

Part Descriptions

LP220303-4   Hepatitis C virus genotype 1 NS5b gene
Nonstructural protein 5B (NS5b) is a viral protein found in hepatitis C virus (HCV), and has the main function of replicating the HCV viral RNA by using the viral positive RNA strand as its template and catalyzing the polymerization of ribonucleoside triphosphates (rNTP). PMID: 22303022 The S282T mutation has been identified as the common variant that can confer resistance to sofosbuvir, however, this mutation is not generally present in untreated patients with HCV. PMID: 24883006 Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis C virus genotype 1 NS5b gene mutations detected
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method
Genotyping

Additional Names

Short Name
HCV Genotyp 1 NS5b Mut Det Islt
Display Name
HCV genotype 1 NS5b gene mutations detected Genotyping Nom (Isol)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) genotype 1 NS5b gene variant analysis

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
14758

Example Answer List LL4044-5

Answer Code Score Answer ID
S282T LA26381-6
L320F LA26389-9
C223H/Y LA26390-7
None Copyright http://snomed.info/sct ID:260413007 None (qualifier value) LA137-2

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Genotyp 1 NS5b-Gen Mutationen entdeckt:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:Genotypisierung
es-ES Spanish (Spain) Gen NS5b del genotipo 1 del virus de la Hepatitis C Detección de mutaciones:Presencia o identidad:Punto temporal:Aislado:Nom:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Se detectaron mutaciones en el gen NS5b del genotipo 1 del virus de la hepatitis C:Presencia o identidad:Punto temporal:Aislado:Nominal:Susceptibilidad del genotipo viral
fr-FR French (France) Hépatite C virus génotype 1 NS5b gène mutations détectées:Identification:Ponctuel:Isolat:Résultat nominal:Génotypage
it-IT Italian (Italy) Epatite C virus, genotipo 1 gene NS5b, mutazioni identificate:Prid:Pt:Isolato:Nom:Genotipizzazione
Synonyms: Gene NS5b genotipo 1 virus dell''epatite C Genotipo 1 virus dell''epatite C Presenza o Identità Punto nel tempo (episodio) Suscettibilità agli antibiotici Suscettibilità al genotipo virale Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype 1 NS5b gen gedetecteerde mutaties:identificator:moment:isolaat:nominaal:genotypering
pl-PL Polish (Poland) Gen NS5b HCV, genotyp 1 wykryte mutacje:wykrycie lub identyfikacja:punkt w czasie:izolat:cecha:genotypowanie
Synonyms: Genotyp wirusa zapalenia wątroby typu C Wykryto mutacje genu NS5b wirusa zapalenia wątroby typu C genotypu 1
zh-CN Chinese (China) 丙型肝炎病毒基因型 1 NS5b 基因 已检出的突变:存在与否或特征标识:时间点:分离株:名义型:基因分型
Synonyms: Ⅰ C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 I 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 1 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 1 NS5b 基因 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 存在;存在与否;特征标识;身份;身份标识 已发现的突变 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 突变 突变类;基因突变 肝 遗传基因;遗传因子;吉恩;生物基因

82513-3 Hepatitis C virus genotype 3 [Presence] in Serum or Plasma by NAA with probe detection

Term Description

This test determines whether the patient is hepatitis C virus genotype 3 and is used to help optimize treatment selection for patients being considered for anti viral therapy such as daclatasvir, an NS5A inhibitor drug.
Source: Regenstrief LOINC

Part Descriptions

LP220415-6   Hepatitis C virus genotype 3
There are six major hepatitis C virus genotypes (1-6), each of which can be further subdivided into subtypes (for example, 1a, 1b, 2a). Genotypes 1, 2 and 3 are widely distributed in developed countries while other genotypes appear to be more geographically localized PMID: 10755999 Genotype 1 (including subtypes 1a and 1b) is the most prevalent by far in the United States. Genotype 3, constitutes 10% of HCV infections in the United States and Canada. Patients with this HCV genotype have a higher incidence of hepatocellular carcinoma, higher prevalence of steatosis and insulin resistance, and faster rates of fibrosis progression compared to patients with other HCV genotypes. Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis C virus genotype 3
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
HCV Gentyp 3 SerPl Ql NAA+probe
Display Name
HCV genotype 3 NAA+probe Ql
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) Genotype 3, Blood

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.63
Order vs. Observation
Both

Example Answer List LL744-4

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Genotyp 3:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Genotipo 3 del virus de la Hepatitis C:PrThr:Punto temporal:Suero o Plasma:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Genotipo 3 del virus de la hepatitis C:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Hépatite C virus génotype 3:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Epatite C virus, genotipo 3:PrThr:Pt:Siero/Plasma:Ord:Sonda.amp.tar
Synonyms: Genotipo 3 virus dell''epatite C Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype 3:aanwezigheid:moment:serum of plasma:ordinaal:probe-detectie
Synonyms: probe.amp.tar
zh-CN Chinese (China) 丙型肝炎病毒基因型 3:存在情况或阈值:时间点:血清/血浆:序数型:探针法.基因扩增.靶向
Synonyms: Ⅲ C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 III 三 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 3 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 扩增型 扩增性 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 经过扩增的 肝 脱氧核糖核酸探针 血清或血浆

82514-1 Hepatitis C virus genotype 3 NS5a gene mutations detected [Identifier]

Part Descriptions

LP220242-4   Hepatitis C virus genotype 3 NS5a gene mutations detected
Hepatitis C virus nonstructural 5a (NS5a) is a phosphoprotein, involved both in viral replication and in many interactions with cellular signaling pathways, including the interferon anti-viral pathway. PMID: 26719254 Mutations, include the Y93H polymorphism, associated with resistance to NS5A inhibitors. Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis C virus genotype 3 NS5a gene mutations detected
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method
Genotyping

Additional Names

Short Name
HCV Gentyp 3 NS5a Mut Det Islt
Display Name
HCV genotype 3 NS5a gene mutations detected Genotyping Nom (Isol)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) genotype 3 NS5a gene variant analysis

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
15176

Example Answer List LL4042-9

Answer Code Score Answer ID
None detected LA19544-8
Y93H LA26376-6
P58R/S LA26379-0
A30K/S/T/V LA26378-2

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Genotyp 3 NS5a-Gen Mutationen entdeckt:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:Genotypisierung
es-ES Spanish (Spain) Gen NS5a del genotipo 3 del virus de la Hepatitis C Detección de mutaciones:Presencia o identidad:Punto temporal:Aislado:Nom:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Se detectaron mutaciones en el gen NS5a del genotipo 3 del virus de la hepatitis C:Presencia o identidad:Punto temporal:Aislado:Nominal:Susceptibilidad del genotipo viral
fr-FR French (France) Hépatite C virus génotype 3 NS5a gène mutations détectées:Identification:Ponctuel:Isolat:Résultat nominal:Génotypage
it-IT Italian (Italy) Epatite C virus, genotipo 3 gene NS5a, mutazioni identificate:Prid:Pt:Isolato:Nom:Genotipizzazione
Synonyms: Gene NS5a genotipo 3 virus dell''epatite C Genotipo 3 virus dell''epatite C Presenza o Identità Punto nel tempo (episodio) Suscettibilità agli antibiotici Suscettibilità al genotipo virale Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus genotype 3 NS5a gen gedetecteerde mutaties:identificator:moment:isolaat:nominaal:genotypering
pl-PL Polish (Poland) Gen NS5a HCV, genotyp 3 wykryte mutacje:wykrycie lub identyfikacja:punkt w czasie:izolat:cecha:genotypowanie
Synonyms: Genotyp wirusa zapalenia wątroby typu C Wykryto mutacje genu NS5a wirusa zapalenia wątroby typu C genotypu 3
zh-CN Chinese (China) 丙型肝炎病毒基因型 3 NS5a 基因 已检出的突变:存在与否或特征标识:时间点:分离株:名义型:基因分型
Synonyms: Ⅲ C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 III 三 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 3 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）基因型 3 NS5a 基因 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 叁 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 存在;存在与否;特征标识;身份;身份标识 已发现的突变 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 突变 突变类;基因突变 肝 遗传基因;遗传因子;吉恩;生物基因

72859-2 Boceprevir [Susceptibility] by Genotype method

Part Descriptions

LP157328-8   Boceprevir
Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Boceprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Boceprevir Islt Genotyp
Display Name
Boceprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Boceprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.73
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Both
Common Test Rank Get Info
12974

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel
72862-6 Hepatitis C virus resistance panel by Genotype method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Boceprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Boceprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Bocéprévir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Boceprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) boceprevir:gevoeligheid:moment:isolaat:ordinaal:genotypering
pt-BR Portuguese (Brazil) Boceprevir::Pt:Isolado:OrdQn:Genotipagem
ru-RU Russian (Russian Federation) Боцепревир:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Boceprevir:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 波普瑞韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 博普瑞韦;博赛泼维;波西普韦;Victrelis;NS3/4A蛋白酶抑制剂;HCV蛋白酶抑制剂;慢性丙型肝炎治疗药物;CAS 394730-60-0;(1R,2S,5S)-N-(4-氨基-1-环丁基-3,4-二氧代丁烷-2-基)-3-[(2S)-2-(叔丁基氨基甲酰氨基)-3,3-二甲基丁酰基]-6,6-二甲基-3-氮杂双环[3.1.0]己烷-2-甲酰胺 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82379-9 Daclatasvir [Susceptibility] by Genotype method

Part Descriptions

LP220247-3   Daclatasvir
Daclatasvir (also called DCV, formerly called BMS-790052, tradename Daklinza) is a first-generation, direct-acting antiviral (DAA) is a zinc-binding and proline-rich hydrophilic phosphoprotein that plays a key role in hepatitis C virus RNA replication. Daclatasvir is used along with other medications, such as sofosbuvir (tradename Solvadi), to treat certain types of chronic hepatitis C. Treatment stops the virus from multiplying and in turn prevents secondary diseases of hepatitis C, including cirrhosis and liver cancer. Patients who have no detectable virus in the blood for a longer a period following treatment may be at lower risk of such secondary diseases. Six different forms of hepatitis C viruses are now known, referred to as genotypes 1 to 6. In clinical studies, the baseline NS5A polymorphism Y93H resulted in reduced rates of sustained virologic response in patients with HCV genotype 3 who were treated for 12 weeks with daclatasvir (plus sofosbuvir), especially in those patients with cirrhosis. In addition, the high mutation rate of the HCV genome, combined with selective pressure from ongoing therapy, can lead to selection of additional HCV variants that are resistant to NS5A inhibitors. PMID: 24659881 Source: Regenstrief LOINC

Fully-Specified Name

Component
Daclatasvir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Daclatasvir Islt Genotyp
Display Name
Daclatasvir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Daclatasvir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
8433

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Dataclasvir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Daclatasvir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Daclatasvir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Daclatasvir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) daclatasvir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 达卡他韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: N,N''-[[1,1''-联苯]-4,4''-二基双[1H-咪唑-5,2-二基-(2S)-2,1-吡咯烷二基 [(1S)-1-(1-甲基乙基)-2-氧代-2,1-乙烷二基]]]双氨基甲酸 C,C''-二甲酯;CAS 1009119-64-5 (1214735-16-6);BMS 790052;EBP 883;Daklinza;N,N''-[[1,1''-Biphenyl]-4,4''-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)- 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82376-5 Elbasvir [Susceptibility] by Genotype method

Term Description

This assay amplifies hepatitis C virus genotypes 1a and 1b to detect the presence of treatment-emergent HCV NS5a variants associated with NS5a inhibitor antiviral therapy.
Source: Regenstrief LOINC

Part Descriptions

LP220248-1   Elbasvir
Elbasvir (formerly MK-8742) is a hepatitis C virus (HCV) NS5A inhibiting antiviral drug for the treatment of HCV infection. It is used for patients with HCV genotype 1 infection, in a combination product with other complementary hepatitis C antiviral drugs such as grazoprevir and MK-3682. PMID: 25467591 Source: Regenstrief LOINC

Fully-Specified Name

Component
Elbasvir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Elbasvir Islt Genotyp
Display Name
Elbasvir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Elbasvir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
8217

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Elbasvir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Elbasvir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Elbasvir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Elbasvir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) Elbasvir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 奥拉帕维:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: MK 8742;CAS 1370468-36-2 (1444832-51-2);ZEPATIER (elbasvir/grazoprevir 复方制剂) 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

92733-5 Glecaprevir [Susceptibility] by Genotype method

Part Descriptions

LP343292-1   Glecaprevir
Glecaprevir is a hepatitis C virus (HCV) NS3/NS4A protease inhibitor. As of 2019, it is available in the U.S. in combination with pibrentasvir, an HCV NS5A inhibitor. The combination drug has high efficacy in treating patients with chronic HCV infection for HCV genotypes 1-6 ("pangenotypic"). PMID: 30977945 Source: Regenstrief LOINC

Fully-Specified Name

Component
Glecaprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Glecaprevir Islt Genotyp
Display Name
Glecaprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Glecaprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Both

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Glecaprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Glecaprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Glécaprévir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Glecaprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
zh-CN Chinese (China) 格卡瑞韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: CAS 1365970-03-1;新型的 HCV NS3/4A 蛋白酶 (HCV NS3/4A protease) 抑制剂 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82523-2 Grazoprevir [Susceptibility] by Genotype method

Part Descriptions

LP220642-5   Grazoprevir
Grazoprevir (previously MK-5172) is a second generation hepatitis C virus (HCV) NS3/4A protease inhibitor, used in combination with the NS5A replication complex inhibitor elbasvir, either with or without ribavirin, for patients with HCV genotype 1 infection with baseline characteristics of poor response. PMID: 25467591 Source: Regenstrief LOINC

Fully-Specified Name

Component
Grazoprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Grazoprevir Islt Genotyp
Display Name
Grazoprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Grazoprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
15014

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Grazoprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Grazoprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Grazoprevir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Grazoprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) Grazoprevir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 格佐普韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: Grazoprevir 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82377-3 Ledipasvir [Susceptibility] by Genotype method

Term Description

This assay amplifies hepatitis C virus genotypes 1a and 1b to detect the presence of treatment-emergent HCV NS5a variants associated with NS5a inhibitor antiviral therapy.
Source: Regenstrief LOINC

Part Descriptions

LP220249-9   Ledipasvir
Ledipasvir is a hepatitis C virus (HCV) NS5A inhibiting antiviral drug for the treatment of HCV. It is used in combination with sofosbuvir, and approved by the FDA for the treatment of chronic hepatitis C genotype 1 infection in adults. PMID: 26788571 Source: Regenstrief LOINC

Fully-Specified Name

Component
Ledipasvir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Ledipasvir Islt Genotyp
Display Name
Ledipasvir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Ledipasvir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
8243

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Ledipasvir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Ledipasvir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Ledipasvir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Ledipasvir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) ledipasvir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 雷迪帕韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: GS 588;CAS 1256388-51-8;Methyl [(2S)-1-[(6S)-6-[4-(9,9-difluoro-7-[2-[(1S,3S,4R)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl]-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]-3-meth 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

30289-3 Nevirapine [Susceptibility] by Genotype method

Part Descriptions

LP21317-0   Nevirapine
Nevirapine is a Nonnucleoside Reverse Transcriptase Inhibitor (Non-NRTI) antiretroviral drug used in the treatment of HIV. Drug resistance reports assist with treatment decisions. Source: Regenstrief Institute

LP21317-0   Nevirapine
Nevirapine, also marketed under the trade name Viramune (Boehringer Ingelheim), is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.

As with other antiretroviral drugs, HIV rapidly develops resistance if nevirapine is used alone, so recommended therapy consists of combinations of three or more antiretrovirals. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Nevirapine
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Nevirapine Islt Genotyp
Display Name
Nevirapine Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Nevirapine

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.04
Last Updated
Version 2.73
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Observation
Common Test Rank Get Info
6961

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel
49660-4 HIV susceptibility panel by Genotype method

Member of these Groups Get Info

LOINC Group Group Name
LG41245-8 NevirapineSusc|Isolate

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) nevirapina:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:genotipificación
es-ES Spanish (Spain) Nevirapina:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Nevirapina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
et-EE Estonian (Estonia) Nevirapiin:Susc:Pt:Is:Ord:Genotüpiseerimine
Synonyms: Isolaat Järgarvuline Juhuslik Tundlikkus
fr-CA French (Canada) Névirapine:Susceptibilité:Temps ponctuel:Isolat:Ordinal:Génotypage
fr-FR French (France) Névirapine:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
fr-BE French (Belgium) Névirapine:Susceptibilité:Temps ponctuel:Isolat:Ordinal:Génotypage
it-IT Italian (Italy) Nevirapina:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
ko-KR Korean (Korea, Republic Of) 네비라핀:감수성:검사시점:분리주:정량 or 순위척도:유전형
nl-NL Dutch (Netherlands) nevirapine:gevoeligheid:moment:isolaat:ordinaal:genotypering
pt-BR Portuguese (Brazil) Nevirapina:Susc:Pt:Isolado:OrdQn:Genotipagem
Synonyms: Viramune; NVP; Nevirapin; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; Genotyp; Genotype; Genotypic; ANTIBIOTIC SUSCEPTIBILITIES
ru-RU Russian (Russian Federation) Невирапин:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Nevirapin:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 奈韦拉平:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: NVP 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82378-1 Ombitasvir [Susceptibility] by Genotype method

Part Descriptions

LP220250-7   Ombitasvir
Ombitasvir (ABT-267) is a hepatitis C virus (HCV) NS5A inhibiting antiviral drug for the treatment of HCV infection. PMID: 25451055. United States FDA approved ombitasvir-paritaprevir-ritonavir and dasabuvir for the treatment of genotype 1 chronic hepatitis C infection in adults, including patients with compensated cirrhosis. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ombitasvir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Ombitasvir Islt Genotyp
Display Name
Ombitasvir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Ombitasvir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
8210

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Ombitasvir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Ombitasvir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Ombitasvir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Ombitasvir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
zh-CN Chinese (China) 翁比他韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: CAS 1258226-87-7;C50H67N7O8;2,2''-[[(2S,5S)-1-[4-(1,1-Dimethylethyl)phenyl]-2,5-pyrrolidinediyl]di-4,1-phenylene]bis[N-(methoxycarbonyl)-L-valyl-L-prolinamide;ABT 267 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82521-6 Paritaprevir [Susceptibility] by Genotype method

Part Descriptions

LP220646-6   Paritaprevir
Paritaprevir (previously known as ABT-450) is an inhibitor of the NS3-4A serine protease, and has demonstrated in vitro antiviral activity against several hepatitis C virus (HCV) genotypes, including 1a, 1b, 2a, 3a, 4a, and 6a. Co-administation with ritonavir, ombitasvir and dasabuvir, referred to as the 3D regimen, has proven effective for the treatment of HCV genotype 1 infection. PMID: 26710243 Source: Regenstrief LOINC

Fully-Specified Name

Component
Paritaprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Paritaprevir Islt Genotyp
Display Name
Paritaprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Paritaprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
14525

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Paritaprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Paritaprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Paritaprevir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Paritaprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) paritaprevir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 帕利瑞韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: Paritaprevir;CAS 1216941-48-8 (1221573-85-8) 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

92735-0 Pibrentasvir [Susceptibility] by Genotype method

Part Descriptions

LP343295-4   Pibrentasvir
Pibrentasvir is a hepatitis C virus (HCV) NS5A protein inhibitor. As of 2019, it is available in the U.S. in combination with glecaprevir, an HCV NS3/NS4A protease inhibitor. The combination drug has high efficacy in treating patients with chronic HCV infection for HCV genotypes 1-6 ("pangenotypic"). PMID: 30977945 Source: Regenstrief LOINC

Fully-Specified Name

Component
Pibrentasvir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Pibrentasvir Islt Genotyp
Display Name
Pibrentasvir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Pibrentasvir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Both

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Pibrentasvir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Pibrentasvir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Pibrentasvir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Pibrentasvir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
zh-CN Chinese (China) 哌仑他韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: CAS 1353900-92-1;ABT-530 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82522-4 Simeprevir [Susceptibility] by Genotype method

Part Descriptions

LP220644-1   Simeprevir
Simeprevir (formerly TMC435, tradenames Olysio and Sovriad) is a second generation, highly specific and potent direct antiviral agent (DAA) inhibitor of HCV NS3/4A protease, for the treatment of hepatitis C virus (HCV) infection. Simeprevir is indicated for treating chronic HCV infection as a part of a triple antiviral treatment regimen along with two other drugs, PEG-IFN and RBV. It is primary efficacious in treating HCV genotype 1 infected patients with compensated liver disease including cirrhosis. PMID: 26904396 Source: Regenstrief LOINC

Fully-Specified Name

Component
Simeprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Simeprevir Islt Genotyp
Display Name
Simeprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Simeprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
15684

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Simeprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Simeprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Simeprevir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Simeprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) simeprevir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 司美匹韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: Simeprevir;CAS 923604-59-5 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

72860-0 Telaprevir [Susceptibility] by Genotype method

Part Descriptions

LP157329-6   Telaprevir
Telaprevir (VX-950), marketed under the brand names Incivek and Incivo, is a pharmaceutical drug for the treatment of hepatitis C. It is a member of a class of antiviral drugs known as protease inhibitors. Telaprevir is only indicated for use against hepatitis c genotype 1 viral infections and hasn't been proven to have an effect on or being safe when used for other genotypes of the virus. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Telaprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Telaprevir Islt Genotyp
Display Name
Telaprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Telaprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.73
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Both
Common Test Rank Get Info
13322

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel
72862-6 Hepatitis C virus resistance panel by Genotype method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Telaprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Telaprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Télaprévir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Telaprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) telaprevir:gevoeligheid:moment:isolaat:ordinaal:genotypering
pt-BR Portuguese (Brazil) Telaprevir::Pt:Isolado:OrdQn:Genotipagem
ru-RU Russian (Russian Federation) Телапревир:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Telaprevir:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 特拉匹韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: VX-950;特拉普韦;特拉匹伟;替拉瑞韦;特拉泼维;泰拉匹韦;CAS 402957-28-2;C36H53N7O6;Cyclopenta©pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydro-, (1S,3aR,6aS)- 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

82520-8 Velpatasvir [Susceptibility] by Genotype method

Part Descriptions

LP220649-0   Velpatasvir
Velpatasvir (previously known as GS-5816) is an inhibitor of the hepatitis C virus (HCV) NS5A protein with antiviral activity across all HCV genotypes (1-6). The combination of velpatasvir and sofosbuvir with or without ribavirin provides high rates of sustained virologic response for patients with chronic HCV. PMID: 26569658 Source: Regenstrief LOINC

Fully-Specified Name

Component
Velpatasvir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Velpatasvir Islt Genotyp
Display Name
Velpatasvir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Velpatasvir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
8273

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Velpatasvir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Velpatasvir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Velpatasvir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Velpatasvir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) velpatasvir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 维帕他韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: Velpatasvir;CAS 1377049-84-7 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

92734-3 Voxilaprevir [Susceptibility] by Genotype method

Part Descriptions

LP343299-6   Voxilaprevir
Voxilaprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor that is active against HCV genotypes 1-6 ("pangenotypic"). In addition, the common resistance-conferring mutations of HCV genotype 1 NS3 have been shown to confer less resistance to voxilprevir than to other protease inhibitors. Voxilaprevir is used in combination with sofosbuvir, an NS5B nucleotide inhibitor, and velpatasvir, an NS5A inhibitor, to treat chronic HCV infection. PMID: 30574189 Source: Regenstrief LOINC

Fully-Specified Name

Component
Voxilaprevir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Voxilaprevir Islt Genotyp
Display Name
Voxilaprevir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Voxilaprevir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Both

Example Answer List LL4039-5

Answer Code Score Answer ID
Resistance predicted LA26373-3
Resistance not predicted LA26374-1

Member of these Panels

LOINC Long Common Name
82525-7 Hepatitis C virus genotype and drug resistance panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Voxilaprevir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Voxilaprevir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Voxilaprévir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Voxilaprevir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
zh-CN Chinese (China) 伏西瑞韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: CAS 1535212-07-7;GS-9857;Voxilaprevir (GS-9857);含氟大环丙型肝炎病毒 (HCV) 非结构蛋白 (NS) 3/4A 蛋白酶抑制剂 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间