Version 2.74

Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID: 101631718]
Source: Regenstrief LOINC

Part Description

LP15816-9   Pregnanetriol
A metabolite of 17-ALPHA-HYDROXYPROTESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-Alpha tetrahydrocortisol

Additional Names

Short Name
Pregntrl/THE+THF+5a-THF Ur-sRto
Display Name
Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol (U) [Molar ratio]
Consumer Name Alpha
Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha Tetrahydrocortisol, Urine

Basic Attributes

First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation

Member of these Panels

LOINC Long Common Name
73886-4 Steroid fractions panel - Urine

Member of these Groups Get Info

LOINC Group Group Name
LG37447-6 Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol|SRto|Urine

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 孕三醇/四氢可的松+四氢皮质醇+5-alpha 四氢皮质醇:物质的量比率:时间点:尿液:定量型:
Synonyms: 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha(α、A) 四氢皮质醇(THC、THF、四氢皮质甾醇、四氢皮醇) 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 THC;THF;四氢皮质甾醇;四氢皮醇 α 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 四氢可的松(四氢考的松)+四氢皮质醇(THC、THF、四氢皮质甾醇、四氢皮醇)+5-alpha(α、A) 四氢皮质醇(THC、THF、四氢皮质甾醇、四氢皮醇);四氢可的松+四氢皮质醇+5-α四氢皮质醇 四氢考的松 尿;小便;下泉 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 阿尔法
es-ES Spanish (Spain) Pregnantriol/Tetrahidrocortisona+tetrahidrocortisol+5-alfa-tetrahidrocortisol:Relacion de Sustancia:Punto temporal:Orina:Qn:
it-IT Italian (Italy) Pregnandiolo/Tetraidrocortisone+tetraidrocortisolo+5-alfa tetraidrocortisolo:Srto:Pt:Urine:Qn:
Synonyms: Chimica Pregnanediolo Punto nel tempo (episodio) Rapporto di sostanza
fr-FR French (France) Prégnanetriol/tétrahydrocortisone+tétrahydrocortisol+5-alpha-tétrahydrocortisol:Moles ratio:Ponctuel:Urine:Numérique:
nl-NL Dutch (Netherlands) pregnaantriol/tetrahydrocortison + tetrahydrocortisol + 5-alfa tetrahydrocortisol:molaire verhouding:moment:urine:kwantitatief:
es-MX Spanish (Mexico) Pregnanetriol / tetrahidrocortisona + tetrahidrocortisol + 5-alfa tetrahidrocortisol:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:

Example Units

Unit Source
{ratio} Example UCUM Units

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