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Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

Part Description

LP71299-9   Glial nuclear type 1
Anti-glial nuclear antibody type 1 (AGNA-1) targets the Sox1 nuclear antigen found in Bergmann cells, a specialized glial cell type found in the cerebellar cortex. AGNA-1 antibodies are associated with paraneoplastic Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic neuropathies associated with small cell lung cancer (SCLC). They have also been associated with non-paraneoplastic neuropathy, which may be an immune-mediated condition. PMID: 20701982 Source: Regenstrief LOINC, PMID: 20701982

LOINC Names Get Info

Fully-Specified Name
Glial nuclear type 1 Ab.IgG:PrThr:Pt:Ser/Plas:Ord:Line blot
Long Common Name
Glial nuclear type 1 IgG Ab [Presence] in Serum or Plasma by Line blot
Short Name
Glial nuc type 1 IgG SerPl Ql Line blot
Display Name
Glial nuclear type 1 IgG Line blot Ql
Consumer Name Alpha Get Info
Glial nuclear type 1 IgG antibody, Blood

Part Model Get Info

  • Component
    Glial nuclear type 1 Ab.IgG
    LP232459-0
    • Analyte
      Glial nuclear type 1 Ab.IgG
      LP232459-0
      • Component Numerator
        Glial nuclear type 1 Ab.IgG
        LP232459-0
        • Component Numerator Core
          Glial nuclear type 1
          LP71299-9
        • Component Numerator Core Suffix
          Ab.IgG
          LP32401-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Line blot
    LP266806-1

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.66 (MIN)
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG50967-5Glial nuclear type 1 Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Antinukleární protilátky IgG gliální typ 1:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Line blot
el-GRGreek (Greece)Γλοιακός πυρηνικός τύπος 1 Αντισώματα IgG:PrThr:Pt:Ορός/Πλάσμα:Ord:Γραμμή κηλίδωσης
Synonyms: Ord PrThr Pt SERO Type Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Γλοιακός πυρηνικός τύπος 1 Γραμμή κηλίδωσης Ορός Ορός/Πλάσμα Πλάσμα Πυρηνικό
es-ESSpanish (Spain)Gliales de tipo nuclear 1 IgG:PrThr:Punto temporal:Suero o Plasma:Ord:Line blot
es-MXSpanish (Mexico)Glial nuclear tipo 1 Ab.IgG:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Mancha de línea
fr-CAFrench (Canada)Gliale nucléaire de type 1, IgG:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)Noyau cellule gliale type 1 Ac IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Blot en ligne
it-ITItalian (Italy)Gliali di tipo nucleare 1 Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:Line blot
Synonyms: anticorpi IgG anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)gliaal nucleair type 1 As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:lijnblot
Synonyms: antistof; antilichaam soort
pl-PLPolish (Poland)Glejowy typ jądrowy 1 Ab.IgG:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:line blot
Synonyms: Anty-glejowe jądrowe typu 1 Ab IgG przeciwciała IgG Przeciwciała IgG jądrowe przeciwglejowe
zh-CNChinese (China)神经胶质细胞核 1 型 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:线点印迹法
Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 I 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 核;胞核 核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 神经胶质细胞核类型 1;神经胶质细胞核 I 型 线点杂交技术;线点杂交法;线条状印迹法 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=83001-8