Version 2.78

Term Description

The percent of cells containing chromosome 12 trisomy can be detected by FISH and used for the diagnosis of chronic lymphocytic leukemia (CLL), multiple myeloma, non-Hodgkin's lymphoma (NHL) as well as other forms of cancer. This term is used to report the number of cells that have the extra chromosome out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are also reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based on, but not limited in use to, the Vysis LSI CEP12 probe, which targets the D12Z3 alpha satellite region.
Source: Regenstrief LOINC

Part Description

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
Cells.chromosome 12 trisomy/Cells counted
Property
NFr
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
FISH

Additional Names

Long Common Name
Cells.chromosome 12 trisomy/Cells counted in Blood or Tissue by FISH
Short Name
Cells.Chr 12 Ts/Cells NFr Bld/T FISH
Display Name
Cells.chromosome 12 trisomy/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha Get Info
Cells.chromosome 12 trisomy/Cells Counted, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRISOMY
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.61
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Trisomía del cromosoma 12/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cells.cromosoma 12 trisomía / Células contadas:Fracción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) Chromosome 12 trisomie %:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT Italian (Italy) Cellule.trisomia cromosoma 12/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH
Synonyms: Frazione numerica Ibridazione in situ fluorescente (FISH) Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Trisomia cromosoma genetica Trisomia del cromosoma 12
nl-NL Dutch (Netherlands) cellen.chromosoom 12 trisomie/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH
pl-PL Polish (Poland) Komórki.Chromosom12 - trisomia/zliczone komórki:frakcja liczbowa:punkt w czasie:krew lub tkanka:ilościowy:fluorescencyjna hybrydyzacja in situ (FISH)
Synonyms: Komórki z monosomią chromosomu 12 Komórki z monosomią chromosomu 12 w stosunku do zliczonych komórek
zh-CN Chinese (China) 细胞.染色体 12 三体性/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH
Synonyms: 12号染色体三体型;12号染色体三体性;染色体 12 三体型 Fluorescent in situ hybridization;荧光原位杂交 三体型 三体细胞 三染色体性 三染色体细胞 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子病理学试验类.三体性（三体型） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 所计数的细胞;计数细胞;所计数细胞;已计数细胞 所计数细胞;已计数过细胞;已计数细胞;已计过数细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体二体型+染色体三体型 细胞.染色体 12 三体性（三体型） 细胞含量;细胞性;细胞性质;细胞构成;细胞类 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84913-3