Version 2.78

Term Description

Deletions at 13q14 involving the RB1 gene can be detected by FISH and used for the diagnosis of chronic lymphocytic leukemia (CLL), multiple myeloma, non-Hodgkin's lymphoma (NHL) as well as other forms of cancer. Labs will report the number of cells that have the deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are also reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI 13 (13q14) probe, which targets the RB1 gene and flanking regions.
Source: Regenstrief LOINC

Part Description

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
Cells.chromosome region 13q14 deletion/Cells counted
Property
NFr
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
FISH

Additional Names

Long Common Name
Cells.chromosome region 13q14 deletion/Cells counted in Blood or Tissue by FISH
Short Name
Cells.13q14 Del/Cells NFr Bld/T FISH
Display Name
Cells.chromosome region 13q14 del/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha Get Info
Cells.chromosome region 13q14/Cells Counted, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.DELDUP
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.61
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Región cromosómica 13q14 Deleción/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Deleción de la región del cromosoma 13q14 / Células contadas:Fracción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) Chromosome région 13q14 % délétion:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT Italian (Italy) Cellule.cromosoma regione 13q14 Delezione/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH
Synonyms: Delezione o duplicazione genica Frazione numerica Ibridazione in situ fluorescente (FISH) Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) cellen.chromosoomgebied 13q14 deletie/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH
pl-PL Polish (Poland) Komórki. region chromosomowy 13q14 delecja/zliczone komórki:frakcja liczbowa:punkt w czasie:krew lub tkanka:ilościowy:fluorescencyjna hybrydyzacja in situ (FISH)
Synonyms: Komórki z delecją regionu 14 na długim ramieniu chromosomu 13 w stosunku do zliczonych komórek Komórki z obecnym regionem 14 na długim ramieniu chromosomu 13
zh-CN Chinese (China) 细胞.染色体区域 13q14 缺失/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH
Synonyms: Fluorescent in situ hybridization;荧光原位杂交 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 区;地区;局部 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 所计数的细胞;计数细胞;所计数细胞;已计数细胞 所计数细胞;已计数过细胞;已计数细胞;已计过数细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体二体型+染色体三体型 染色体区域（染色体部位、染色体区、染色体区带、染色体部） 13q14 染色体缺失;染色体区带缺失;基因缺失;缺损;基因缺损;基因删除;删除;基因丢失 染色体部位;染色体区;染色体区带;染色体部;染色体区域（染色体部位、染色体区、染色体区带、染色体部） 细胞.染色体区域（染色体部位、染色体区、染色体区带、染色体部） 13q14 细胞含量;细胞性;细胞性质;细胞构成;细胞类 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84914-1