85092-5
Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot
Active
72318-9 Centromere protein A IgG Ab [Presence] in Serum or Plasma by Immunoassay
Term Description
Centromere protein A (CENP-A) IgG class autoantibodies can be detected by enzyme immunoassays. Results may be interpreted by humans or automated methods and used for the diagnosis of system sclerosis (SSc, diffuse and limited forms) and overlapping syndromes. This code was created for, but not limited to, the detection of CENP-A autoantibodies in Euroimmun's Systemic Sclerosis (Nucleoli) Profile EUROLINE (IgG) test kit.
Source: Regenstrief LOINC
Part Descriptions
LP157222-3 Centromere protein A
Centromere protein A (CENP-A) is an essential centromere protein encoded by the CENPA gene. Overexpression of CENP-A causes chromosomal aberrations, and depletion of CENP-A promotes apoptosis and induces cell cycle arrest. Overexpression of CENP-A has been associated with high grade cancers and is a prognostic factor for patients with estrogen receptor (ER)-positive breast cancer. Antibodies to CENP-A are associated with scleroderma, systemic sclerosis, CREST syndrome, and other rheumatologic diseases.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Centromere protein A Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- CENP A IgG SerPl Ql IA
- Display Name
- Centromere protein A IgG IA Ql
- Consumer Name Alpha Get Info
- Centromere Protein A IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Example Answer List LL2206-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Borderline | LA4259-3 | ||
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Strong positive | LA18996-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CENP-A-IgG-AK ql. |
| es-ES | Spanish (Spain) | Proteína A del centrómero (CENP-A) IgG: |
| es-MX | Spanish (Mexico) | Centrómero de proteína A Ab.IgG: |
| fr-FR | French (France) | Centromère protéine A anticorps IgG: |
| it-IT | Italian (Italy) | Centromero, proteina A Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunoassay Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | centromeereiwit A As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Proteína A do Centrômero Ac.IgG: |
| ru-RU | Russian (Russian Federation) | Центромерный протеин A Ат.IgG: Synonyms: Антитело Белок Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Sentromer protein A Ab.IgG: Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 着丝粒蛋白 A 抗体.IgG: Synonyms: A IgG A 型 A 型抗体 Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
82913-5 Centromere protein B IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Centromere protein B Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- Centromere B IgG Ser Ql Line blot
- Display Name
- Centromere protein B IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Centromere Protein B IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CENP-B-IgG-AK ql. |
| es-ES | Spanish (Spain) | Proteína B del centrómero IgG: |
| es-MX | Spanish (Mexico) | Centrómero de proteína B Ab.IgG: |
| fr-CA | French (Canada) | Centromère protéine B, IgG: |
| fr-FR | French (France) | Centromère protéine B anticorps IgG: |
| it-IT | Italian (Italy) | Centromero, proteina B Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Proteina B del centromero Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | centromeereiwit B As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | 着丝点蛋白 B 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
85095-8 D-3-phosphoglycerate dehydrogenase IgG Ab [Presence] in Serum by Line blot
Term Description
The qualitative result for the detection of IgG antibodies to D-3-phosphoglycerate dehydrogenase (PGDH) antigens in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot).
Source: Regenstrief LOINC
Part Descriptions
LP200136-2 D-3-phosphoglycerate dehydrogenase
D-3-phosphoglycerate dehydrogenase (3-PGDH) is encoded by the PHGDH gene, located on chromosome 1p12, and functions as part of the L-serine biosynthesis pathway to catalyze the conversion of 3-phospho-D-glycerate to 3-phosphohydroxypyruvate. Defects in the PHGDH gene are associated with two disorders: phosphoglycerate dehydrogenase(PGDH) deficiency and Neu-Laxova syndrome 1 (NLS1). PGDH deficiency is associated with congenital microcephaly, psychomotor retardation, and seizures. NLS1 is a lethal, autosomal recessive syndrome associated with ichthyosis, marked intrauterine growth restriction, microcephaly, hypoplastic lungs and central nervous system anomalies. [UniProt: O43175] Antibodies to 3-PGDH are detected in patients with chronic liver diseases, primiarily autoimmune hepatitis (AIH). PMID: 21707887
Source: Regenstrief LOINC, UniProt: O43175
Fully-Specified Name
- Component
- D-3-phosphoglycerate dehydrogenase Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- 3-PGDH IgG Ser Ql Line blot
- Display Name
- D-3-phosphoglycerate dehydrogenase IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- D-3-phosphoglycerate dehydrogenase IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.67
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Preferred Answer List LL2206-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Borderline | LA4259-3 | ||
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Strong positive | LA18996-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | D-3-fosfoglicerato deshidrogenasa IgG: |
| es-MX | Spanish (Mexico) | D-3-fosfoglicerato deshidrogenasa IgG: |
| fr-FR | French (France) | 3-PGDH anticorps IgG: |
| it-IT | Italian (Italy) | D-3-deidrogenasi fosfoglicerato Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | D-3-fosfoglyceraat-dehydrogenase As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | D-3-磷酸甘油酸脱氢酶 抗体.IgG: Synonyms: Ⅲ Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
82921-8 Liver cytosol IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP18289-6 Liver cytosol
Liver cytosol (LC-1) autoantibodies can be detected in patients with autoimmune hepatitis type 2. LC-1 are usually not associated with autoimmune hepatitis type 1, drug-induced hepatitis, or primary biliary cirrhosis.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Liver cytosol Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- Liver Cytosol IgG Ser Ql Line blot
- Display Name
- Liver cytosol IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Liver cytosol IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Citosol hepático IgG: |
| es-MX | Spanish (Mexico) | Citosol hepático Ab.IgG: |
| fr-CA | French (Canada) | Cytosol hépatique, IgG: |
| fr-FR | French (France) | Cytosol hépatique anticorps IgG: |
| it-IT | Italian (Italy) | Citosol epatico Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | levercytosol As.IgG: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Cytozol hepatocytów Ab.IgG: Synonyms: Cytozol komórek wątroby IgG Przeciwciała do cytoplazmy komórek wątroby Przeciwciała IgG do cytozolu komórek wątroby |
| zh-CN | Chinese (China) | 肝脏细胞溶质 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
69952-0 Liver kidney microsomal 1 IgG Ab [Presence] in Serum by Immunoassay
Part Descriptions
LP38960-8 Liver kidney microsomal 1 Ab.IgG
Liver kidney microsome 1 Ab: A positive result indicates the presence of IgG antibodies to recombinant human P450 2D6 and suggests the possibility of autoimmune hepatitis, type 2. A negative LKM-1 does not rule out the presence of autoimmune hepatitis, type 2.
Source: ARUP Laboratories, LKM-1
Fully-Specified Name
- Component
- Liver kidney microsomal 1 Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- LKM-1 IgG Ser Ql IA
- Display Name
- Liver kidney microsomal 1 IgG IA Ql (S)
- Consumer Name Alpha Get Info
- Liver kidney microsomal 1 IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.68
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG17140-1 | Liver kidney microsomal 1 Ab.IgG| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Anticuerpos anti microsomal hepático 1 IgG: |
| es-MX | Spanish (Mexico) | Hígado riñón microsomal 1 Ab.IgG: |
| et-EE | Estonian (Estonia) | Maksa-neeru mikrosomaalne 1 antikehad.IgG: Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Microsome hépatique et rénal 1, IgG: |
| fr-FR | French (France) | LKM 1 microsomes foie rein anticorps IgG: |
| fr-BE | French (Belgium) | Microsome hépatique et rénal 1 Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Fegato rene, microsomiali 1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunoassay Microsomi epatici Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | lever-nier-microsomaal 1 As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Microssomal de Fígado e Rim 1 Ac.IgG: |
| ru-RU | Russian (Russian Federation) | Печеночно-почечные микросомы 1 Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Karaciğer böbrek mikrozomal 1 Ab.IgG: Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 肝肾微粒体 1 抗体.IgG: Synonyms: Ⅰ Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
82928-3 Mitochondria M2 IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP29153-1 Mitochondria M2
Mitochondrial Antibody is present in approximately 95% of patients with primary biliary cirrhosis (PBC). Mitochondrial M2 Antibody has an even higher specificity for PBC.
Source: Quest Diagnostics Inc., Mitochondrial antibody
Fully-Specified Name
- Component
- Mitochondria M2 Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- Mitochondria M2 IgG Ser Ql Line blot
- Display Name
- Mitochondria M2 IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Mitochondria M2 IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Mitocondrial (M2) IgG: |
| es-MX | Spanish (Mexico) | Mitocondrias M2 Ab.IgG: |
| fr-CA | French (Canada) | Mitochondrie M2, IgG: |
| fr-FR | French (France) | Mitochondries M2 anticorps IgG: |
| it-IT | Italian (Italy) | Mitocondri M2 Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | mitochondriaal M2 As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | 线粒体 M2 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
72320-5 Mitochondria M2-3E IgG Ab [Presence] in Serum by Immunoassay
Term Description
Autoantibodies directed against a recombinant mitochondrial fusion protein, M2-3E (BPO), can be detected by enzyme immunoassays. Results may be interpreted by humans or automated methods and used for the diagnosis of primary biliary cirrhosis. This code was created for, but not limited to, the detection of M2-3E autoantibodies by Euroimmun's EUROLINE Profile Autoimmune Liver Diseases (IgG) test kit.
Source: Regenstrief LOINC
Part Descriptions
LP157237-1 Mitochondria M2-3E
M2-3E (BPO) antigen is a recombinant fusion protein that is made up of the E2 subunits of the branched-chain 2-oxoacid dehydrogenase (BCOADH), pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (OGDH). The presence of anti-mitochondrial antibodies (AMA) against M2-3E antigens is used for the diagnosis of primary biliary liver cirrhosis (PBC), an immune-mediated chronic inflammatory liver disease of unknown cause. Approximately 86% of patients with PBC have M2-3E autoantibodies.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Mitochondria M2-3E Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- M2-3E IgG Ser Ql IA
- Display Name
- Mitochondria M2-3E IgG IA Ql (S)
- Consumer Name Alpha Get Info
- Mitochondria M2-3E IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Mitocondria M2-3E IgG: |
| es-MX | Spanish (Mexico) | Mitocondrias M2-3E Ab.IgG: |
| fr-FR | French (France) | Mitochondries M2-3E anticorps IgG: |
| it-IT | Italian (Italy) | Mitocondri M2-3E Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | mitochondriaal M2-3E As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Mitocondria M2-3E Ac.IgG: |
| ru-RU | Russian (Russian Federation) | Митохондрия M2-3E Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Mitokondri M2-3E Ab.IgG: Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 线粒体 M2-3E 抗体.IgG: Synonyms: Ab.IgG; |
82931-7 Nuclear pore protein gp210 IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP71756-8 Nuclear pore protein gp210
Nuclear pore glycoprotein-210 (gp210) is an essential trafficking regulator in the eukaryotic nuclear pore complex. Gp-210 anchors the pore complex to the nuclear membrane and protein tagging reveals its primarily located on the luminal side of double layer membrane at the pore. A single polypeptide motif of gp210 is responsible for sorting to nuclear membrane,and indicate the carboxyl tail of the protein is oriented toward the cytoplasmic side of the membrane.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Nuclear pore protein gp210 Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- Nucl pore prot gp210 IgG Ser Ql Ln blot
- Display Name
- Nuclear pore protein gp210 IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Nuclear pore protein gp210 IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Proteína gp20 de los poros nucleares IgG: |
| es-MX | Spanish (Mexico) | Proteína de poro nuclear gp210 Ab.IgG: |
| fr-FR | French (France) | Pore nucléaire proteine gp210 anticorps IgG: |
| it-IT | Italian (Italy) | Pori nucleari, proteina gp210 Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Proteina gp210 dei pori nucleari Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | nucleair porieproteïne gp210 As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | 核孔蛋白 gp210 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
82923-4 PML IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- PML Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- PML IgG Ser Ql Line blot
- Display Name
- PML IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- PML IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | PML IgG: |
| es-MX | Spanish (Mexico) | PML Ab.IgG: |
| fr-CA | French (Canada) | PML, IgG: |
| fr-FR | French (France) | PML anticorps IgG: |
| it-IT | Italian (Italy) | PML Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | PML As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | PML 抗体.IgG: Synonyms: Ab.IgG; |
17570-3 SCL-70 extractable nuclear IgG Ab [Presence] in Serum by Immunoassay
Part Descriptions
LP16758-2 SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469
Source: Regenstrief LOINC, PMID: 11229469
Fully-Specified Name
- Component
- SCL-70 extractable nuclear Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- ENA Scl70 IgG Ser Ql IA
- Display Name
- SCL-70 extractable nuclear IgG IA Ql (S)
- Consumer Name Alpha Get Info
- SCL-70 extractable nuclear IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0l
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 13114
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG5142-7 | SCL-70 extractable nuclear Ab.IgG| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Scl-70 IgG-AK ql. |
| es-AR | Spanish (Argentina) | SCL-70 nuclear extraíble: |
| es-ES | Spanish (Spain) | Antígeno nuclear extraíble SCL-70 IgG: |
| es-MX | Spanish (Mexico) | Ab.IgG nuclear extraíble SCL-70: |
| fr-CA | French (Canada) | SCL-70 nucléaire soluble, IgG: |
| fr-FR | French (France) | SCL-70 anticorps IgG: |
| fr-BE | French (Belgium) | SCL-70 nucléaire soluble Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Nucleare estraibile SCL-70 Ab.IgG: Synonyms: anticorpi IgG anticorpo ENA Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| ko-KR | Korean (Korea, Republic Of) | SCL-70 추출성 핵 항체.면역글로불린 G: |
| nl-NL | Dutch (Netherlands) | SCL-70 extraheerbare nucleaire As.IgG: Synonyms: antistof; |
| pl-PL | Polish (Poland) | SCL-70 rozpuszczalny jądrowy Ab.IgG: Synonyms: IgG Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała IgG do jądra komórkowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy |
| pt-BR | Portuguese (Brazil) | SCL-70 Ac.IgG: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | SCL-70 экстрагируемый ядерный Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | SCL-70 özütlenebilir nükleer Ab.IgG: Synonyms: Ak Ak.IgG Çekirdek İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | SCL-70 可提取性核 抗体.IgG: Synonyms: Ab.IgG; |
82933-3 Sjogrens syndrome-A extractable nuclear 52kD IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP69895-8 Sjogrens syndrome-A extractable nuclear 52kD
Antibodies against the 52-kd Ro(SS-A) protein are significantly associated with the primary Sjogren's syndrome (pSS).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Sjogrens syndrome-A extractable nuclear 52kD Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- ENA SS-A 52kD IgG Ser Ql Line blot
- Display Name
- Sjogrens syndrome-A extractable nuclear 52kD IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Sjogrens syndrome-A extractable nuclear 52kD IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL2010-8
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Borderline | LA4259-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Ag extraible nuclear de 52 kD del Síndrome de Sjogrens IgG: |
| es-MX | Spanish (Mexico) | Síndrome de Sjogrens-A nuclear extraíble 52kD Ab.IgG: |
| fr-CA | French (Canada) | Syndrome de Sjögren-a nucléaire soluble 52kD, IgG: |
| fr-FR | French (France) | SSA/Ro52 kD anticorps IgG: |
| it-IT | Italian (Italy) | Sjogren, sindrome -nucleare estraibile A 52kD Ab.IgG: Synonyms: anticorpi IgG anticorpo ENA Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Sindrome di Sjorgen - nucleare estraibile A Sindrome di Sjorgen - nucleare estraibile A 52kD |
| nl-NL | Dutch (Netherlands) | syndroom van Sjögren-A extraheerbare nucleaire 52kD As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | Sjogrens 综合征-a 可提取性核 52kD 抗体.IgG: Synonyms: A 型 Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
17585-1 Sjogrens syndrome-A extractable nuclear IgG Ab [Presence] in Serum by Immunoassay
Part Descriptions
LP16760-8 Sjogrens syndrome-A extractable nuclear
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. PMID: 27184054
Source: Regenstrief LOINC, PMID: 27184054
Fully-Specified Name
- Component
- Sjogrens syndrome-A extractable nuclear Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- ENA SS-A IgG Ser Ql IA
- Display Name
- Sjogrens syndrome-A extractable nuclear IgG IA Ql (S)
- Consumer Name Alpha Get Info
- Sjogrens syndrome-A extractable nuclear IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0l
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6712
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG5159-1 | Sjogrens syndrome-A extractable nuclear Ab.IgG| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Αντι-Ro (SSA) IgG ανοσοσφαιρίνη: Synonyms: Ab IgG |
| es-AR | Spanish (Argentina) | síndrome de Sjögren-A nuclear extraíble: |
| es-ES | Spanish (Spain) | Antígeno nuclear extraíble Síndrome de Sjogren-A (SS-A) IgG: |
| es-MX | Spanish (Mexico) | Síndrome de Sjogrens-A nuclear extraíble Ab.IgG: |
| fr-CA | French (Canada) | Syndrome de Sjögren-a nucléaire soluble, IgG: |
| fr-FR | French (France) | SSA/Ro anticorps IgG: |
| fr-BE | French (Belgium) | Syndrome de Sjögren-a nucléaire soluble Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Sjogren, sindrome-nucleare estraibile A Ab.IgG: Synonyms: anticorpi IgG anticorpo ENA Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Sindrome di Sjorgen - nucleare estraibile A |
| ko-KR | Korean (Korea, Republic Of) | 쇼그렌 증후군-A 추출성 핵 항체.면역글로불린 G: |
| nl-NL | Dutch (Netherlands) | SS-A extraheerbare nucleaire As.IgG: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Zespół Sjogrena-A rozpuszczalny jądrowy Ab.IgG: Synonyms: IgG Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała IgG do jądra komórkowego Przeciwciała przeciwjądrowe |
| pt-BR | Portuguese (Brazil) | SS-A Ac.IgG: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Шегрена синдром-A экстрагируемый ядерный Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Sjögrens sendromu-A özütlenebilir nükleer Ab.IgG: Synonyms: Ak Ak.IgG Çekirdek İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | Sjogrens 综合征-a 可提取性核 抗体.IgG: Synonyms: A 型 Ab.IgG; |
78433-0 Soluble liver IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP71714-7 Soluble liver
The presence of SLA antibodies has almost 100% specificity for autoimmune hepatitis, although only 12-30% have these antibodies. Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.
Source: ARUP Laboratories, SLA
Fully-Specified Name
- Component
- Soluble liver Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- Soluble liver IgG Ser Ql Line blot
- Display Name
- Soluble liver IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Soluble liver IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.64
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Hígado soluble IgG: |
| es-MX | Spanish (Mexico) | Ab.IgG soluble en hígado: |
| fr-CA | French (Canada) | Foie soluble, IgG: |
| fr-FR | French (France) | Antigène hépatique soluble anticorps IgG: |
| it-IT | Italian (Italy) | Fegato solubile Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | soluble liver antigen As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | 可溶性肝 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
82932-5 sp100 IgG Ab [Presence] in Serum by Line blot
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- sp100 Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- sp100 IgG Ser Ql Line blot
- Display Name
- sp100 IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- sp100 IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Example Answer List LL2010-8
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Borderline | LA4259-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85092-5 | Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | sp100 IgG: |
| es-MX | Spanish (Mexico) | sp100 Ab.IgG: |
| fr-CA | French (Canada) | sp100, IgG: |
| fr-FR | French (France) | Protéine Sp-100 anticorps IgG: |
| it-IT | Italian (Italy) | sp100 Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | sp100 As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | sp100 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.