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Part Description

LP247956-8   Mitotic rate
The degree of mitotic activity in breast carcinoma is one component of the Nottingham histologic grade (NHG) LOINC 44648-4, which is a prognostic indicator for patients with breast carcinoma. The two other components of the NHG are tubule formation LOINC 85321-8 and nuclear pleomorphism LOINC 44645-0. Mitotic activity is assessed as the number of mitoses per 10 high power fields (HPF), with increasing mitotic activity being an indicator of more aggressive cancer. The specific scores assigned to the number of mitoses depends on the size of the HPF. For example, for a HPF size of 0.274 mm^2, less than 10 mitoses per 10 HPF gets a score of 1, 10-19 gets a score of 2, and greater than or equal to 20 gets a score of 3. When larger or smaller HPFs are used, the cutoffs for the number of mitoses corresponding to a specific score are adjusted according to published guidelines. PMID: 11865000 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Mitotic rate:Score:Pt:Breast cancer specimen:SemiQn:Nottingham
Long Common Name
Mitotic rate [Score] in Breast cancer specimen by Nottingham
Short Name
Mitotic rate Scre Br ca spec Nottingham
Display Name
Mitotic rate Nottingham (Breast cancer specimen) [Score]
Consumer Name Alpha Get Info
Mitotic rate, Breast cancer specimen

Part Model Get Info

  • Component
    Mitotic rate
    LP247956-8
    • Analyte
      Mitotic rate
      LP247956-8
      • Component Numerator
        Mitotic rate
        LP247956-8
        • Component Numerator Core
          Mitotic rate
          LP247956-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Score
    LP185820-0
  • Time
    Pt
    LP6960-1
  • System
    Breast cancer specimen
    LP247851-1
    • System Core
      Breast cancer specimen
      LP247851-1
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    Nottingham
    LP248063-2

Normative Answer List: LL4383-7

Source: College of American Pathologists
AnswerCodeScoreAnswer ID
Score 11LA27225-4
Score 22LA27226-2
Score 33LA27227-0
No residual invasive carcinoma after presurgical (neoadjuvant) therapy0LA27220-5
Score cannot be determined0LA27221-3

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.82 (MIN)
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
85904-1Cancer pathology panel - Breast cancer specimen by CAP cancer protocols

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Mitotická aktivita:Skóre:Časový bod:Vzorek karcinomu prsu:Semikvantitativní:Nottinghamská klasifikace
el-GRGreek (Greece)Μιτωτικός ρυθμός:Βαθμολογία:Pt:Δείγμα καρκίνου του μαστού:Ημιποσοτική:Nottingham
Synonyms: Nottingham PATH Pt Αξία Βαθμολογία Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του μαστού Ημιποσοτική Καρκίνος Μαστός Μιτωτικός ρυθμός
es-ESSpanish (Spain)indice mitotico:Puntuación:Punto temporal:Muestra de cancer de mama:Semicuantitativo:Nottingham
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Tasa mitótica:Puntaje:Punto temporal:Muestra de cáncer de mama:Ordinal:Nottingham
it-ITItalian (Italy)Tasso mitotico:Punteggio:Pt:Tumore della mammella, campione:SemiQn:Nottingham
Synonyms: Campione di tumore Campione di tumore della mammella Neoplasia maligna Patologia Petto Punto nel tempo (episodio)
zh-CNChinese (China)有丝分裂率:评分:时间点:乳腺癌标本:半定量型:诺丁汉法
Synonyms: Nottingham 法 乳房 乳腺癌（乳癌）标本（样本、样品、试样） 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 分值;得分;分数 受检物 时刻;随机;随意;瞬间 样品 样本 癌 癌（癌症、癌变）标本（样本、样品、试样） 试样 速度

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85300-2