Version 2.80

Term Description

This term is used to report the interpretation of results from an HIV immunoassay testing algorithm that may be based on third, fourth, fifth and possibly other generations of HIV immunoassays. HIV testing has evolved significantly in the past 30 years. The first three generations of HIV immunoassays detected HIV antibodies (first IgG only, then IgG and IgM). The fourth-generation tests can detect, but not differentiate between, HIV-1 and HIV-2 antibodies as well as the HIV-1 p24 antigen. The inclusion of the p24 antigen allows for detection of HIV as early as two weeks after exposure and before seroconversion occurs (i.e. before antibodies are produced). In 2014, the U.S. Centers for Disease Control and Prevention published a recommended algorithm for HIV diagnostic testing based on fourth-generation HIV immunoassays [https://stacks.cdc.gov/view/cdc23447]. More recently, fifth-generation HIV immunoassays have been developed, which can detect and differentiate between HIV-1 and HIV-2 antibodies and the HIV-1 p24 antigen. The CDC is in the process of updating its testing algorithm and the latest information can be found at https://www.cdc.gov/hiv/testing/laboratorytests.html. Note that third generation assays are still available in the U.S. and earlier generations may also be available outside the U.S.

Fully-Specified Name

Component
HIV immunoassay testing algorithm interpretation
Property
Imp
Time
Pt
System
Ser/Plas/Bld
Scale
Nom
Method

Additional Names

Long Common Name
HIV immunoassay testing algorithm interpretation in Serum, Plasma or Blood
Short Name
HIV IA algorithm interp SerPlBld-Imp
Display Name
HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp]
Consumer Name Alpha Get Info
HIV immunoassay testing algorithm interpretation, Blood

Example Answer List: LL4332-4

Source: Association of Public Health Laboratories
Answer Code Score Answer ID
No serologic evidence of infection with HIV. Cannot exclude incubating or early HIV infection. Submit second sample in 3-4 weeks if clinically indicated. LA27091-0
Serologic evidence of HIV-1 infection is present. Refer to physician for care. LA27092-8
Positive for HIV antibodies but could not be differentiated as HIV-1 or HIV-2. Refer to physician for care. LA27115-7
Serologic evidence of HIV-2 infection is present. Refer to physician for care. LA27114-0
Serologic evidence of acute HIV infection is present. Refer to physician for care and follow-up NAT testing. If NAT is nonreactive or not tested, submit second sample in 3-4 weeks to rule out HIV infection. LA27116-5

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61 (ADD)
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ερμηνεία αλγορίθμου ανοσοδοκιμασίας του ιού της ανθρώπινης ανοσοανεπάρκειας:Imp:Pt:Ορός/Πλάσμα/Αίμα:Nom:
Synonyms: Imp Ερμηνεία Ερμηνεία αλγορίθμου ανοσοδοκιμασίας του ιού της ανθρώπινης ανοσοανεπάρκειας Ιός ανθρώπινης ανοσοανεπάρκειας
es-ES Spanish (Spain) Interpretación del algoritmo de la prueba de inmunoensayo del HIV:Impresión/interpretación del estudio:Punto temporal:Suero, Plasma o Sangre:Nom:
es-MX Spanish (Mexico) Interpretación del algoritmo de prueba de inmunoensayo del VIH:Impresión / interpretación del estudio:Punto temporal:Suero, plasma o sangre:Nominal:
fr-FR French (France) VIH interprétation test IA:Interprétation:Ponctuel:Sérum/Plasma/Sang:Résultat nominal:
it-IT Italian (Italy) HIV, interpretazione algoritmo test dosaggio immunologico:Imp:Pt:Siero/Plasma/Sangue:Nom:
Synonyms: Impressione/interpretazione di studio Interpretazione algoritmo test dosaggio immunologi Microbiologia Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma Siero,Plasma o Sangue
zh-CN Chinese (China) HIV 免疫测定法检测算法解释:印象:时间点:血清/血浆/全血:名义型:
Synonyms: AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV（艾滋病病毒、人类免疫缺陷病毒、艾滋病毒、human immunodeficiency virus） 免疫测定法（免疫测定、免疫检定法、免疫检定、免疫分析法、免疫分析）检测算法解释 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 判读;解释说明;说明;释义;阐明 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 血;血液 血浆或全血;血浆/血液;血浆或血液 血清、血浆或全血;血清、血浆或血液;血清/血浆/血液 血清或血浆

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