85551-0
PRRSV European and North American strains neutralizing antibody panel - Serum by Neutralization test
Active
85548-6 PRRSV European strain neutralizing antibody [Titer] in Serum by Neutralization test
Term Description
Neutralization methods such as fluorescent focus neutralization (FFN) is used to confirm positive Porcine Reproductive and Respiratory Syndrome (PRRS) results found with screening methods such as ELISA. It uses sample and control serums that are diluted and incubated on the PRRSV infected cells followed by florescent microscopic examination for characteristic patterns of fluorescent staining. Confirmatory tests are pivotal to provide a definitive diagnosis because false positives or negatives result in significant economic loss to livestock producers.
Part Descriptions
LP174537-3 Porcine reproductive and respiratory syndrome virus European strain
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) causes an infection in pigs sometimes known as Blue-Ear Pig Disease. This economically important pandemic disease causes reproductive failure in breeding stock and respiratory tract illness and has shown differences in virulence, tissue trophism and replication capabilities among strains.
PRRSV has two genotypes - the North American strain (type 2 PRRSv, with the isolate prototype VR2332) and the European strain (type 1 PRRSv, with the isolate prototype "Lelystad"). Both types were discovered in their local regions around 1990 but they now share worldwide distributions. These two main genotypes differ genetically by approximately 40%. Within each genotype there is nucleotide divergence of up to 30% (Leung et al., 2010). The majority of the nucleotides that make up the two are the same but diversity within each genotype is high with a significant geographic pattern for the various types. The use of sequence information to compare PRRSV isolates is a valuable tool to monitor PRRSV strains both globally and within a farm over time. It can differentiate between resident and newly introduced viruses as well as between vaccine and field strains.
PMID: 12167339
[http://www.porcilis-prrs.com/prrs-infection.asp]
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Porcine reproductive and respiratory syndrome virus European strain Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- Neut
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.75 (MAJ)
- Change Reason
- Abbreviated "Porcine reproductive and respiratory syndrome virus" to "PRRSV" in the Long Common Name. PRRSV is shorter and more commonly used in test names.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85551-0 | PRRSV European and North American strains neutralizing antibody panel - Serum by Neutralization test |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Ευρωπαϊκό στέλεχος του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ab.Neut: Synonyms: Titr Ευρωπαϊκό στέλεχος του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ιός Ιός του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Των χοίρων |
| es-MX | Spanish (Mexico) | Virus del síndrome respiratorio y reproductivo porcino cepa europea Ab.Neut: |
| es-ES | Spanish (Spain) | Cepa europea del virus del síndrome reproductivo y respiratorio porcino Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
| it-IT | Italian (Italy) | Virus della sindrome riproduttiva e respiratoria del suino, variante Europea Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Variante Europea virus PRRS Virus PRRS |
| nl-NL | Dutch (Netherlands) | 'porcine' reproductief en respiratoir syndroomvirus Europese strain As.neutraliserend: Synonyms: antistof; |
| zh-CN | Chinese (China) | 猪生殖与呼吸综合征病毒欧洲株 抗体.中和: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
85549-4 PRRSV European strain neutralizing antibody [Presence] in Serum by Neutralization test
Term Description
Neutralization methods such as fluorescent focus neutralization (FFN) is used to confirm positive Porcine Reproductive and Respiratory Syndrome (PRRS) results found with screening methods such as ELISA. It uses sample and control serums that are diluted and incubated on the PRRSV infected cells followed by florescent microscopic examination for characteristic patterns of fluorescent staining. Antibody can be detected in experimenally infected pigs 7 to 10 days post inoculation. Serum samples are screened at a 1:20 dilution to determine the presence or absence of the organism. (USDA).
Part Descriptions
LP174537-3 Porcine reproductive and respiratory syndrome virus European strain
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) causes an infection in pigs sometimes known as Blue-Ear Pig Disease. This economically important pandemic disease causes reproductive failure in breeding stock and respiratory tract illness and has shown differences in virulence, tissue trophism and replication capabilities among strains.
PRRSV has two genotypes - the North American strain (type 2 PRRSv, with the isolate prototype VR2332) and the European strain (type 1 PRRSv, with the isolate prototype "Lelystad"). Both types were discovered in their local regions around 1990 but they now share worldwide distributions. These two main genotypes differ genetically by approximately 40%. Within each genotype there is nucleotide divergence of up to 30% (Leung et al., 2010). The majority of the nucleotides that make up the two are the same but diversity within each genotype is high with a significant geographic pattern for the various types. The use of sequence information to compare PRRSV isolates is a valuable tool to monitor PRRSV strains both globally and within a farm over time. It can differentiate between resident and newly introduced viruses as well as between vaccine and field strains.
PMID: 12167339
[http://www.porcilis-prrs.com/prrs-infection.asp]
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Porcine reproductive and respiratory syndrome virus European strain Ab.Neut
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Neut
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.64 (MIN)
- Change Reason
- Abbreviated "Porcine reproductive and respiratory syndrome virus" to "PRRSV" in the Long Common Name. PRRSV is shorter and more commonly used in test names.
- Order vs. Observation
- Observation
Example Answer List LL3596-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 | ||
| Inconclusive Copyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85551-0 | PRRSV European and North American strains neutralizing antibody panel - Serum by Neutralization test |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Ευρωπαϊκό στέλεχος του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ab.Neut: Synonyms: PrThr Ευρωπαϊκό στέλεχος του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ιός Ιός του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Των χοίρων |
| es-MX | Spanish (Mexico) | Virus del síndrome respiratorio y reproductivo porcino cepa europea Ab.Neut: |
| es-ES | Spanish (Spain) | Cepa europea del virus del síndrome reproductivo y respiratorio porcino Anticuerpos antineutrófilos: |
| it-IT | Italian (Italy) | Virus della sindrome riproduttiva e respiratoria del suino, variante Europea Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Variante Europea virus PRRS Virus PRRS |
| nl-NL | Dutch (Netherlands) | 'porcine' reproductief en respiratoir syndroomvirus Europese strain As.neutraliserend: Synonyms: antistof; |
| zh-CN | Chinese (China) | 猪生殖与呼吸综合征病毒欧洲株 抗体.中和: Synonyms: Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
85550-2 PRRSV North American strain neutralizing antibody [Presence] in Serum by Neutralization test
Term Description
Neutralization methods such as fluorescent focus neutralization (FFN) is used to confirm positive Porcine Reproductive and Respiratory Syndrome (PRRS) results found with screening methods such as ELISA. It uses sample and control serums that are diluted and incubated on the PRRSV infected cells followed by florescent microscopic examination for characteristic patterns of fluorescent staining. Antibody can be detected in experimenally infected pigs 7 to 10 days post inoculation. Serum samples are screened at a 1:20 dilution to determine the presence or absence of the organism. (USDA).
Part Descriptions
LP174536-5 Porcine reproductive and respiratory syndrome virus North American strain
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) causes an infection in pigs sometimes known as Blue-Ear Pig Disease. This economically important pandemic disease causes reproductive failure in breeding stock and respiratory tract illness and has shown differences in virulence, tissue trophism and replication capabilities among strains.
PRRSV has two genotypes - the North American strain (type 2 PRRSv, with the isolate prototype VR2332) and the European strain (type 1 PRRSv, with the isolate prototype "Lelystad"). Both types were discovered in their local regions around 1990 but they now share worldwide distributions. These two main genotypes differ genetically by approximately 40%. Within each genotype there is nucleotide divergence of up to 30% (Leung et al., 2010). The majority of the nucleotides that make up the two are the same but diversity within each genotype is high with a significant geographic pattern for the various types. The use of sequence information to compare PRRSV isolates is a valuable tool to monitor PRRSV strains both globally and within a farm over time. It can differentiate between resident and newly introduced viruses as well as between vaccine and field strains.
PMID: 12167339
[http://www.porcilis-prrs.com/prrs-infection.asp]
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Porcine reproductive and respiratory syndrome virus North American strain Ab.Neut
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Neut
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.64 (MIN)
- Change Reason
- Abbreviated "Porcine reproductive and respiratory syndrome virus" to "PRRSV" in the Long Common Name. PRRSV is shorter and more commonly used in test names.
- Order vs. Observation
- Observation
Example Answer List LL3596-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 | ||
| Inconclusive Copyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85551-0 | PRRSV European and North American strains neutralizing antibody panel - Serum by Neutralization test |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Στέλεχος Βόρειας Αμερικής του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ab.Neut: Synonyms: PrThr Ιός Ιός του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Στέλεχος Βόρειας Αμερικής του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Των χοίρων |
| es-MX | Spanish (Mexico) | Virus del síndrome respiratorio y reproductivo porcino cepa norteamericana Ab.Neut: |
| es-ES | Spanish (Spain) | Cepa norteamericana del virus del síndrome reproductivo y respiratorio porcino Anticuerpos antineutrófilos: |
| it-IT | Italian (Italy) | Virus della sindrome riproduttiva e respiratoria del suino, variante Nord Americana Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Variante Nord Americana virus PRRS Virus PRRS |
| nl-NL | Dutch (Netherlands) | 'porcine' reproductief en respiratoir syndroomvirus Noord-Amerikaanse strain As.neutraliserend: Synonyms: antistof; |
| zh-CN | Chinese (China) | 猪生殖与呼吸综合征病毒北美株 抗体.中和: Synonyms: Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
85547-8 PRRSV North American strain neutralizing antibody [Titer] in Serum by Neutralization test
Term Description
Neutralization methods such as fluorescent focus neutralization (FFN) is used to confirm positive Porcine Reproductive and Respiratory Syndrome (PRRS) results found with screening methods such as ELISA. It uses sample and control serums that are diluted and incubated on the PRRSV infected cells followed by florescent microscopic examination for characteristic patterns of fluorescent staining. Confirmatory tests are pivotal to provide a definitive diagnosis because false positives or negatives result in significant economic loss to livestock producers.
Part Descriptions
LP174536-5 Porcine reproductive and respiratory syndrome virus North American strain
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) causes an infection in pigs sometimes known as Blue-Ear Pig Disease. This economically important pandemic disease causes reproductive failure in breeding stock and respiratory tract illness and has shown differences in virulence, tissue trophism and replication capabilities among strains.
PRRSV has two genotypes - the North American strain (type 2 PRRSv, with the isolate prototype VR2332) and the European strain (type 1 PRRSv, with the isolate prototype "Lelystad"). Both types were discovered in their local regions around 1990 but they now share worldwide distributions. These two main genotypes differ genetically by approximately 40%. Within each genotype there is nucleotide divergence of up to 30% (Leung et al., 2010). The majority of the nucleotides that make up the two are the same but diversity within each genotype is high with a significant geographic pattern for the various types. The use of sequence information to compare PRRSV isolates is a valuable tool to monitor PRRSV strains both globally and within a farm over time. It can differentiate between resident and newly introduced viruses as well as between vaccine and field strains.
PMID: 12167339
[http://www.porcilis-prrs.com/prrs-infection.asp]
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Porcine reproductive and respiratory syndrome virus North American strain Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- Neut
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.75 (MAJ)
- Change Reason
- Abbreviated "Porcine reproductive and respiratory syndrome virus" to "PRRSV" in the Long Common Name. PRRSV is shorter and more commonly used in test names.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85551-0 | PRRSV European and North American strains neutralizing antibody panel - Serum by Neutralization test |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Στέλεχος Βόρειας Αμερικής του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ab.Neut: Synonyms: Titr Ιός Ιός του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Στέλεχος Βόρειας Αμερικής του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Των χοίρων |
| es-ES | Spanish (Spain) | Cepa norteamericana del virus del síndrome reproductivo y respiratorio porcino Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Virus del síndrome respiratorio y reproductivo porcino cepa norteamericana Ab.Neut: |
| it-IT | Italian (Italy) | Virus della sindrome riproduttiva e respiratoria del suino, variante Nord Americana Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Variante Nord Americana virus PRRS Virus PRRS |
| nl-NL | Dutch (Netherlands) | 'porcine' reproductief en respiratoir syndroomvirus Noord-Amerikaanse strain As.neutraliserend: Synonyms: antistof; |
| zh-CN | Chinese (China) | 猪生殖与呼吸综合征病毒北美株 抗体.中和: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |