85624-5 Kidney failure 2-year risk [Likelihood] by KFRE

Term Description

The two-year "treated kidney failure" risk as calculated by the Kidney Failure Risk Equation (KFRE), for patients with chronic kidney disease stages 3 to 5. "Treated kidney failure" is defined as kidney failure that is treated with either dialysis or kidney transplant. The KFRE includes the following variables: patient age, sex, estimated glomerular filtration rate (eGFR), and urinary albumin-creatinine ratio (ACR). In this model, all variables are time-independent, in that the baseline measurement is used for all calculations. PMID: 26757465

Fully-Specified Name

Component

Kidney failure 2Y risk

Property

Likelihood

Time

Pt

System

^Patient

Scale

Qn

Method

KFRE

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.61

Last Updated

Version 2.64 (MIN)

Change Reason

Corrected log to natural log (ln) in the formula

Order vs. Observation

Both

Formula (Readable)

1 - 0.9750 ^ exp (-0.2201 × (age/10 - 7.036) + 0.2467 × (male - 0.5642) - 0.5567 × (eGFR/5 - 7.222) + 0.4510 × (lnACR - 5.137)); male is valued as 1 if patient is male, and 0 if patient is female

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• Kidney fail 2Y risk
• Kidney Failure Risk Equation - dynamic
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Risk

Example Units

Copyright

Organization

Dr. Navdeep Tangri

Copyright

Copyright © Dr. Navdeep Tangri

Terms of Use

Used with permission

URL

http://kidneyfailurerisk.com/

85625-2 Kidney failure 5-year risk [Likelihood] by KFRE

Term Description

The five-year "treated kidney failure" risk as calculated by the Kidney Failure Risk Equation (KFRE), for patients with chronic kidney disease stages 3 to 5. "Treated kidney failure" is defined as kidney failure that is treated with either dialysis or kidney transplant. The KFRE includes the following variables: patient age, sex, estimated glomerular filtration rate (eGFR), and urinary albumin-creatinine ratio (ACR). In this model, all variables are time-independent, in that the baseline measurement is used for all calculations. PMID: 26757465

Fully-Specified Name

Component

Kidney failure 5Y risk

Property

Likelihood

Time

Pt

System

^Patient

Scale

Qn

Method

KFRE

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.61

Last Updated

Version 2.64 (MIN)

Change Reason

Corrected log to natural log (ln) in the formula

Order vs. Observation

Both

Formula (Readable)

1 - 0.9240 ^ exp (-0.2201 × (age/10 - 7.036) + 0.2467 × (male - 0.5642) - 0.5567 × (eGFR/5 - 7.222) + 0.4510 × (lnACR - 5.137)); ; male is valued as 1 if patient is male, and 0 if patient is female

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• Kidney fail 5Y risk
• Kidney Failure Risk Equation - dynamic
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Risk

Example Units

Copyright

Organization

Dr. Navdeep Tangri

Copyright

Copyright © Dr. Navdeep Tangri

Terms of Use

Used with permission

URL

http://kidneyfailurerisk.com/

29553-5 Age calculated

Fully-Specified Name

Component

Age

Property

Time

Time

Pt

System

^Patient

Scale

Qn

Method

Calculated

Basic Attributes

Class

MISC

Type

Laboratory

First Released

Version 2.03

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Observation

Common Test Rank Get Info

10563

Member of these Panels

Language Variants Get Info

Related Names

• Calc
• Calculation
• MISC
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random

Example Units

46098-0 Sex

Part Descriptions

LP101395-4   Sex
In LOINC, sex refers to the biological sex of an organism, which is most commonly determined based on anatomy and physiology or genetic (chromosome) analysis. Our definition is based on the World Health Organization's definition of sex and gender: sex (male, female) refers to biological and physiological characteristics, and gender (masculine, feminine) refers to socially constructed roles, behaviors, activities, and attributes. (http://www.who.int/gender/whatisgender/en) Source: Regenstrief LOINC, WHO: gender

Fully-Specified Name

Component

Sex

Property

Type

Time

Pt

System

^Patient

Scale

Nom

Method

Basic Attributes

Class

ADMIN.PATIENT.DEMOG

Type

Clinical

First Released

Version 2.17

Last Updated

Version 2.73 (MIN)

Change Reason

Changed Component from 'Gender' to 'Sex' to align with the World Health Organization (WHO) definition of this concept.

Order vs. Observation

Both

Common Test Rank Get Info

2086

HL7^® Attributes

HL7^® Field ID

PID-8

Example Answer List LL1-9

Member of these Panels

Language Variants Get Info

Related Names

• ADMIN
• ADMIN.PATIENT
• ADMIN.PT.DEMOG
• AOEObservation
• Gender
• Nominal
• Point in time
• Random
• Typ

Related Codes

32294-1 Albumin/Creatinine [Ratio] in Urine

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP6118-6   Albumin
A non-glycosylated protein that is synthesized in the liver parenchymal cells, regulated by colloid osmotic pressure from interstitial fluid surrounding hepatocytes, and catabolized in nearly all organs. Albumin comprises >50% of plasma proteins in plasma, CSF and urine, and therefore is a key contributor to intravascular oncotic pressure and regulating fluid concentration in tissues. Albumin also binds and transports a variety of endogenous substances and medications. Serum albumin measurement is a reflection of hydration and nutritional status, blood oncotic pressure, liver and kidney function, and other chronic diseases, and the ratio of albumin in the CSF and serum can be used to evaluate blood brain barrier disorders. [Tietz] Urine albumin of less than 30 mg/day is considered normal. Microalbuminuria is defined as urine albumin of 30-300 mg/day and is an early sign of kidney damage from disorders such as diabetes or hypertension. Albuminuria is urine albumin >300 mg/day and is associated with overt kidney disease. PMID: 25512779 Source: Regenstrief LOINC

Reference Information

Fully-Specified Name

Component

Albumin/Creatinine

Property

Ratio

Time

Pt

System

Urine

Scale

Qn

Method

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.07

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Both

Common Test Rank Get Info

3620

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Alb
• Chemistry
• CR
• Crea
• Creat
• Kidney
• Nephrology
• Point in time
• Protein.albumin
• QNT
• Quan
• Quant
• Quantitative
• Random
• Ratios
• Renal
• Rto
• UA
• UCr
• UR
• Urn

Example Units

69405-9 Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by based on 1.73 sq M

Fully-Specified Name

Component

Glomerular filtration rate

Property

ArVRat

Time

Pt

System

Ser/Plas/Bld

Scale

Qn

Method

based on 1.73 sq M

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.38

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: eGFR measurement representation in LOINC had changed in LOINC: Component: Glomerular filtration rate, and Method: .../1.73 sq.M among non-black population or …/1.73 sq.M among black population, and others….; Previous Releases: System changed from "Ser/Plas" to "Ser/Plas/Bld". According to the National Kidney Disease Education Program (NKDEP) Lab Working Group, estimated GFR may be calculated based on blood, serum, or plasma creatinine levels. Whole blood methods are calibrated to be the same as serum/plasma methods, and the isotope dilution mass spectrometry (IDMS) reference measurement procedure is the same for whole blood, serum, and plasma.

Order vs. Observation

Both

Common Test Rank Get Info

381

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Blood
• Chemistry
• GFR
• Glom
• Kidney
• Nephrology
• Pl
• PlasBld
• Plasma
• Plsm
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Renal
• SerP
• SerPl
• SerPlas
• SerPlBld
• Serum
• Serum or plasma
• Serum, plasma or whole blood
• Square Meter
• SR
• Volume rate/area
• Volume Rate/Ratio
• WB
• Whole blood

Example Units