Version 2.78

Term Description

This test reports the presence of the GES carbapenemase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Description

LP248287-7   Bacterial carbapenem resistance blaGES gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some gram negative bacilli that confer resistance to the majority of beta-lactam antibiotics, include the penicillins, cephalosporins and the monobactam aztreonam. ESBLs are most often plasmid-borne. Specific ESBLs include TEM, SHV, and the CTX-M groups, which are the most clinically prevalent, and VEB, PER, BEL, and GES, which are less common. PMID: 19246801 -TEM and SHV subtypes are derived from amino acid substitutions, resulting in enzymatic hydrolysis of many beta-lactam antibiotics. -CTX-M genes originate from Kluyvera species. They are separated based on their amino acid sequences into the following groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. -VEB, PER, BEL, and GES genes are less common. [Mayo Medical Laboratories] The nomenclature for ESBL genes includes the prefix "bla", which stands for "beta-lactam", followed by the enzyme (ie. blaTEM). Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaGES gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
blaGES Islt/Spm Ql
Display Name
Carbapenem resistance blaGES gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info
Carbapenem resistance blaGES gene

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.67
Change Reason
Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
104991-5 Bacterial resistance panel
97324-8 Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
85502-3 Carbapenemase resistance genes panel by Molecular genetics method
93698-9 Gram negative bacterial resistance panel by Molecular genetics method

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bakterielle Carbapenem-Resistenz blaGES-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
es-ES Spanish (Spain) gen bacteriano blaGES resistente a carbapenem:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX Spanish (Mexico) Gen blaGES de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR French (France) Résistance bactérienne aux carbapénèmases blaGES gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, gene blaGES:PrThr:Pt:Isolato/Campione:Ord:Molgen
Synonyms: Gene blaGES di resistenza batterica ai carbapenemici Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaGES-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
Synonyms: bacterieel carbapenem resistentie blaGES gen isolaat/specimen molgen
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaGES 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内,用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分离株/标本(样本、样品、试样) 分离物;分离菌;分离菌株;隔离种群 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 样品 样本 电阻 碳青霉烯类;碳青霉烯类抗生素 细菌性 细菌的 细菌细菌碳青霉烯类(碳青霉烯类抗生素、碳青霉烯)耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) blaGES 基因 耐性 试样 遗传基因;遗传因子;吉恩;生物基因 阻力

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85823-3