Version 2.78

Status Information

Status
DISCOURAGED
Comment
Recommend using the term with System Isolate/Specimen and Method Molgen that aligns with the new LOINC model for molecular resistance testing that was approved by Laboratory LOINC Committee in June 2018
Map-To Long Common Name Mapping Guidance
85498-4 Carbapenem resistance blaIMP gene [Presence] by Molecular method

Term Description

This test reports the presence of the IMP bacterial carbapenemase resistance type gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Descriptions

LP248294-3   Bacterial carbapenem resistance blaIMP gene
Plasmid-mediated IMP-type carbapenemases are currently known to have 17 varieties. Studies have revealed its establishment in Japan in the 1990s in enteric Gram-negative organisms, Pseudomonas species and Acinetobacter species. IMP genes usually co-exist with other resistance genes resulting in multi-drug resistance.
Studies have shown that a high percentage of patients with immunodeficiency and drug resistant nosocomial infections are infected with a VIM or IMP producing organism, particularly when the organism identified is pseudomonas aeruginosa. The two genes are often present together although they can also be present individually. Identifying the presence of these genes is important in monitoring drug resistance and determining the best antibiotic therapy methods.
PMID: 27563634 PMID: 28085553 Source: Regenstrief LOINC

LP265773-4   Bacterial ABXBACT probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaIMP gene
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
blaIMP Islt Ql NAA+probe
Display Name
Carbapenem resistance blaIMP gene NAA+probe Ql (Isol)
Consumer Name Alpha Get Info
Carbapenem resistance blaIMP gene

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.67
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Carbapenem Resistenz Gen (blaIMP) ql.
de-DE German (Germany) Bakterielle Carbapenem-Resistenz blaIMP-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) gen bacteriano blaIMP resistente a carbapenem:PrThr:Punto temporal:Aislado:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Gen blaIMP de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:Aislado:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Résistance bactérienne aux carbapénèmases blaIMP gène:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, gene blaIMP:PrThr:Pt:Isolato:Ord:Sonda.amp.tar
Synonyms: Gene blaIMP di resistenza batterica ai carbapenemici Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaIMP-gen:aanwezigheid:moment:isolaat:ordinaal:probe-detectie
Synonyms: bacterieel carbapenem resistentie blaIMP gen probe.amp.tar
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaIMP 基因:存在情况或阈值:时间点:分离株:序数型:探针法.基因扩增.靶向
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分离物;分离菌;分离菌株;隔离种群 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 扩增型 扩增性 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 电阻 碳青霉烯类;碳青霉烯类抗生素 细菌性 细菌的 细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaIMP 基因 经过扩增的 耐性 脱氧核糖核酸探针 遗传基因;遗传因子;吉恩;生物基因 阻力

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85824-1