85824-1

Carbapenem resistance blaIMP gene [Presence] by NAA with probe detection

Discouraged

Status Information

Status: DISCOURAGED
Comment: Recommend using the term with System Isolate/Specimen and Method Molgen that aligns with the new LOINC model for molecular resistance testing that was approved by Laboratory LOINC Committee in June 2018

Map-To	Long Common Name	Mapping Guidance
85498-4	Carbapenem resistance blaIMP gene [Presence] by Molecular method

Term Description

This test reports the presence of the IMP bacterial carbapenemase resistance type gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.

Part Descriptions

LP248294-3 Bacterial carbapenem resistance blaIMP gene
Plasmid-mediated IMP-type carbapenemases are currently known to have 17 varieties. Studies have revealed its establishment in Japan in the 1990s in enteric Gram-negative organisms, Pseudomonas species and Acinetobacter species. IMP genes usually co-exist with other resistance genes resulting in multi-drug resistance.
Studies have shown that a high percentage of patients with immunodeficiency and drug resistant nosocomial infections are infected with a VIM or IMP producing organism, particularly when the organism identified is pseudomonas aeruginosa. The two genes are often present together although they can also be present individually. Identifying the presence of these genes is important in monitoring drug resistance and determining the best antibiotic therapy methods.
PMID: 27563634 PMID: 28085553 Source: Regenstrief LOINC

LP265773-4 Bacterial ABXBACT probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial carbapenem resistance blaIMP gene:PrThr:Pt:Isolate:Ord:Probe.amp.tar
Long Common Name: Carbapenem resistance blaIMP gene [Presence] by NAA with probe detection
Short Name: blaIMP Islt Ql NAA+probe
Display Name: Carbapenem resistance blaIMP gene NAA+probe Ql (Isol)
Consumer Name Alpha Get Info: Carbapenem resistance blaIMP gene

Part Model Get Info

Component
Bacterial carbapenem resistance blaIMP gene
LP248294-3
- Analyte
  Bacterial carbapenem resistance blaIMP gene
  LP248294-3
  - Component Numerator
    Bacterial carbapenem resistance blaIMP gene
    LP248294-3
    - Component Numerator Core
      Bacterial carbapenem resistance blaIMP gene
      LP248294-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.67 (MIN)
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen blaIMP bakteriální rezistence na karbapenemy:Přítomnost nebo práh:Časový bod:Izolát:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-AT	German (Austria)	Synonyms: Carbapenem Resistenz Gen (blaIMP) ql.
de-DE	German (Germany)	Bakterielle Carbapenem-Resistenz blaIMP-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Γονίδιο blaIMP βακτηριακής ανθεκτικότητας στις καρβαπενέμες:PrThr:Pt:Απομονωμένο στέλεχος:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: ABXBACT Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Απομονωμένο στέλεχος Γονίδιο Γονίδιο blaIMP βακτηριακής ανθεκτικότητας στις καρβαπενέμες Καρβαπενέμη
es-ES	Spanish (Spain)	gen bacteriano blaIMP resistente a carbapenem:PrThr:Punto temporal:Aislado:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	Gen blaIMP de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:Aislado:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Résistance bactérienne aux carbapénèmases gène blaIMP:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Resistenza batterica ai carbapenemici, gene blaIMP:PrThr:Pt:Isolato:Ord:Sonda.amp.tar Synonyms: Gene blaIMP di resistenza batterica ai carbapenemici Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële carbapenemresistentie blaIMP-gen:aanwezigheid:moment:isolaat:ordinaal:probe-detectie Synonyms: bacterieel carbapenem resistentie blaIMP gen probe.amp.tar
pl-PL	Polish (Poland)	Gen blaIMP oporności bakteryjnej na karbapenemy:granica wykrywalności:punkt w czasie:izolat:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Antybiotyk karbapenemowy
zh-CN	Chinese (China)	细菌碳青霉烯类耐药 blaIMP 基因:存在情况或阈值:时间点:分离株:序数型:探针法.基因扩增.靶向 Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向分离物;分离菌;分离菌株;隔离种群存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）扩增型扩增性抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间电阻碳青霉烯类;碳青霉烯类抗生素细菌性细菌的细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaIMP 基因经过扩增的耐性脱氧核糖核酸探针遗传基因;遗传因子;吉恩;生物基因阻力

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.