85840-7

Beta-lactam resistance ESBL blaVEB gene [Presence] by Molecular method

Active

Term Description

This test reports the presence of the blaVEB extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Description

LP248286-9 Bacterial beta-lactam resistance ESBL blaVEB gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some gram negative bacilli that confer resistance to the majority of beta-lactam antibiotics, include the penicillins, cephalosporins and the monobactam aztreonam. ESBLs are most often plasmid-borne. Specific ESBLs include TEM, SHV, and the CTX-M groups, which are the most clinically prevalent, and VEB, PER, BEL, and GES, which are less common. PMID: 19246801 -TEM and SHV subtypes are derived from amino acid substitutions, resulting in enzymatic hydrolysis of many beta-lactam antibiotics. -CTX-M genes originate from Kluyvera species. They are separated based on their amino acid sequences into the following groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. -VEB, PER, BEL, and GES genes are less common. [Mayo Medical Laboratories] The nomenclature for ESBL genes includes the prefix "bla", which stands for "beta-lactam", followed by the enzyme (ie. blaTEM). Source: Regenstrief LOINC

Fully-Specified Name

Component: Bacterial beta-lactam resistance ESBL blaVEB gene
Property: PrThr
Time: Pt
System: Isolate/Specimen
Scale: Ord
Method: Molgen

Additional Names

Long Common Name: Beta-lactam resistance ESBL blaVEB gene [Presence] by Molecular method
Short Name: ESBL blaVEB gene Islt/Spm Ql
Display Name: Beta-lactam resistance ESBL blaVEB gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info: Beta-lactam Resistance ESBL blaVEB gene

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.67
Change Reason: Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
93698-9	Gram negative bacterial resistance panel by Molecular genetics method

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Bakterielle Beta-Lactam-Resistenz ESBL blaVEB-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch Synonyms: Extended Spectrum beta-lactamases
es-ES	Spanish (Spain)	gen bacteriano ESBL blaVEB resistente a beta-lactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX	Spanish (Mexico)	Resistencia bacteriana a betalactámicos BLEE gen blaVEB:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR	French (France)	Résistance bactérienne aux bêta lactamases ESBL blaVEB gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	Resistenza batterica beta-lactamica, gene ESBL blaVEB:PrThr:Pt:Isolato/Campione:Ord:Molgen Synonyms: Gene ESBL blaVEB di resistenza batterica beta-lact Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële bètalactamresistentie ESBL blaVEB-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek Synonyms: bacterieel beta-lactam resistentie ESBL blaVEB gen isolaat/specimen molgen
zh-CN	Chinese (China)	细菌 beta-内酰胺耐药 ESBL blaVEB 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法 Synonyms: B β 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间样品样本电阻细菌 beta-内酰胺（β-内酰胺）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） ESBL（超广谱β-内酰胺酶） blaVEB 基因细菌性细菌的耐性试样贝塔遗传基因;遗传因子;吉恩;生物基因阻力

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