LOINC Panel Details 85905-8 Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

33725-3 Tumor site

Term Description

The site in the body where the tumor is located. For example, in colorectal cancers, the tumor sites include the cecum, ascending or descending colon, hepatic flexure, splenic flexure, or rectum.

Fully-Specified Name

Component: Tumor site
Property: Anat
Time: Pt
System: Specimen
Scale: Nom
Method

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.73 (MIN)
Change Reason: Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
Order vs. Observation: Observation
Common Test Rank Get Info: 10199

Example Answer List LL4310-0

Answer	Code	Score	Answer ID
Cecum			LA16833-8
Ascending colon			LA16834-6
Hepatic flexure			LA16835-3
Transverse colon			LA16836-1
Splenic flexure			LA16837-9
Descending colon			LA16838-7
Sigmoid colon			LA16839-5
Rectosigmoid junction			LA26985-4
Rectum			LA16840-3

Member of these Panels

LOINC	Long Common Name
85904-1	Cancer pathology panel - Breast cancer specimen by CAP cancer protocols
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
98249-6	Cancer pathology panel - Endometrial cancer specimen
81186-9	Gastric cancer pathology panel

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Θέση όγκου:Anat:Pt:Δείγμα:Nom: Synonyms: Anat Θέση όγκου
es-AR	Spanish (Argentina)	localización tumoral:anatomía:punto en el tiempo:espécimen:Nominal:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Localización del tumor:Anatatomia:Punto temporal:Especimen:Nom:
es-MX	Spanish (Mexico)	Sitio del tumor:Anatomía:Punto temporal:Muestra:Nominal:
it-IT	Italian (Italy)	Tumore, sito:Anat:Pt:Campione:Nom: Synonyms: Anatomia Patologia Posto;Luogo Protocolli patologia - generale Punto nel tempo (episodio) Sito di neoplasia
nl-NL	Dutch (Netherlands)	tumorafmeting:anatomie:moment:monster:nominaal:
pt-BR	Portuguese (Brazil)	Local do tumor:Anat:Pt:Amostra:Nom:Protocolos de cancer do CAP Synonyms: Anatomy; Point in time; Random; Spec; Nominal; CAP protocol; PATHOLOGY PROTOCOLS general
ru-RU	Russian (Russian Federation)	Опухоль локализация:Анат:ТчкВрм:Образец:Ном: Synonyms: Анатомия Номинальный;Именной порция;образец;материал для анализа Точка во времени;Момент
tr-TR	Turkish (Turkey)	Tümör bölgesi:Anat:Zmlı:Örnek:Snf: Synonyms: Spesmen
zh-CN	Chinese (China)	肿瘤部位:解剖学:时间点:标本:名义型: Synonyms: 一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通位点;位置供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物时刻;随机;随意;瞬间样品样本病理学.方案病理学原始记录病理学方案解剖;解剖结构试样

33756-8 Polyp size greatest dimension

Fully-Specified Name

Component: Polyp size greatest dimension
Property: Len
Time: Pt
System: Specimen
Scale: Qn
Method

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.70 (MIN)
Change Reason: Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μέγεθος πολύποδα μεγαλύτερη διάσταση:Len:Pt:Δείγμα:Qn: Synonyms: Len Διαστάσεις Μέγεθος Μέγεθος πολύποδα μεγαλύτερη διάσταση
es-AR	Spanish (Argentina)	mayor dimensión del tamaño del pólipo:longitud:punto en el tiempo:espécimen:cuantitativo:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Tamaño mayor de dimensión del pólipo:Longitud:Punto temporal:Especimen:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Tamaño del pólipo mayor dimensión:Largo:Punto temporal:Muestra:Cuantitativo:
it-IT	Italian (Italy)	Dimensione polipo, dimensione maggiore:Len:Pt:Campione:Qn: Synonyms: Dimensione maggiore di dimensione polipo Lunghezza Patologia Protocolli patologia - generale Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	poliepgrootte grootste afmeting:afmeting:moment:monster:kwantitatief: Synonyms: lengte
pt-BR	Portuguese (Brazil)	Pólipo.maior dimensão de tamanho:Comprimento:Pt:Amostra:Qn:Protocolos de cancer do CAP Synonyms: ; Polyp size greatest dim; Length; Point in time; Random; Spec; Quantitative; QNT; Quant; Quan; CAP protocol; PATHOLOGY PROTOCOLS general
ru-RU	Russian (Russian Federation)	Полип размер наибольшее измерение:Дл:ТчкВрм:Образец:Колич: Synonyms: Длина Количественный порция;образец;материал для анализа Точка во времени;Момент
tr-TR	Turkish (Turkey)	Polip büyüklüğü ne geniş boyut:Uzn:Zmlı:Örnek:Kant: Synonyms: Spesmen Süre
zh-CN	Chinese (China)	息肉大小最大尺寸:长度:时间点:标本:定量型: Synonyms: 一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通供检查用的材料;待检物;待试验物;样品;样本;试料;试样受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺外形尺寸;外型尺寸;维度;维;大小尺寸时刻;随机;随意;瞬间样品样本病理学.方案病理学原始记录病理学方案试样长;长短

Example Units

Unit	Source
cm	Example UCUM Units

33757-6 Polyp size additional dimensions

Fully-Specified Name

Component: Polyp size additional dimensions
Property: Len
Time: Pt
System: Specimen
Scale: Qn
Method

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.70 (MIN)
Change Reason: Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μέγεθος πολύποδα πρόσθετες διαστάσεις:Len:Pt:Δείγμα:Qn: Synonyms: Len Μέγεθος Μέγεθος πολύποδα πρόσθετες διαστάσεις
es-AR	Spanish (Argentina)	dimensiones adicionales al tamaño del pólipo:longitud:punto en el tiempo:espécimen:cuantitativo:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Tamaño del pólipo dimensiones adicionales:Longitud:Punto temporal:Especimen:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Dimensiones adicionales del tamaño del pólipo:Largo:Punto temporal:Muestra:Cuantitativo:
it-IT	Italian (Italy)	Dimensione polipo, dimensioni addizionali:Len:Pt:Campione:Qn: Synonyms: Dimensioni addizionali di dimensione polipo Lunghezza Patologia Protocolli patologia - generale Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	poliepgrootte aanvullende afmetingen:afmeting:moment:monster:kwantitatief: Synonyms: lengte
pt-BR	Portuguese (Brazil)	Pólipo.dimensão de tamanho adicional:Comprimento:Pt:Amostra:Qn:Protocolos de cancer do CAP Synonyms: ; Polyp size add'l dim; Length; Point in time; Random; Spec; Quantitative; QNT; Quant; Quan; CAP protocol; Add; PATHOLOGY PROTOCOLS general
ru-RU	Russian (Russian Federation)	Полип размер дополнительные измерения:Дл:ТчкВрм:Образец:Колич: Synonyms: Длина Количественный порция;образец;материал для анализа Точка во времени;Момент
tr-TR	Turkish (Turkey)	Polip büyüklüğü ek boyutları:Uzn:Zmlı:Örnek:Kant: Synonyms: Spesmen Süre
zh-CN	Chinese (China)	息肉大小附加维度:长度:时间点:标本:定量型: Synonyms: 一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通供检查用的材料;待检物;待试验物;样品;样本;试料;试样受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺尺寸息肉大小额外尺寸;息肉大小附加尺寸时刻;随机;随意;瞬间样品样本病理学.方案病理学原始记录病理学方案试样长;长短附加的额外额外的

Example Units

Unit	Source
cm	Example UCUM Units

33758-4 Polyp stalk length by CAP cancer protocols

Fully-Specified Name

Component: Polyp stalk length
Property: Prid
Time: Pt
System: Specimen
Scale: Nom
Method: CAP cancer protocols

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.61 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μήκος μίσχου πολύποδα:Prid:Pt:Δείγμα:Nom:Πρωτόκολλα CAP για τον καρκίνο Synonyms: Prid Μήκος Μήκος μίσχου πολύποδα
es-AR	Spanish (Argentina)	largo del tallo de pólipo:presencia o identidad:punto en el tiempo:espécimen:Nominal:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Longitud del tallo de los pólipos:Presencia o identidad:Punto temporal:Especimen:Nom:Protocolo CAP de cáncer
es-MX	Spanish (Mexico)	Longitud del tallo del pólipo:Presencia o identidad:Punto temporal:Muestra:Nominal:Protocolos de cáncer de CAP
it-IT	Italian (Italy)	Polipo, lunghezza gambo:Prid:Pt:Campione:Nom:Protocolli cancro CAP Synonyms: Lunghezza gambo di polipo Patologia Presenza o Identità Protocolli neoplasia maligna CAP Protocolli patologia - generale Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	poliep steellengte:identificator:moment:monster:nominaal:CAP-kankerprotocollen
pt-BR	Portuguese (Brazil)	Comprimento do pedúnculo do pólipo:Ident:Pt:Amostra:Nom:Protocolos de cancer do CAP Synonyms: Len; Identity or presence; Point in time; Random; Spec; Nominal; CAP protocol; PATHOLOGY PROTOCOLS general
tr-TR	Turkish (Turkey)	Polip gizli uzunluğu:MevcKimlik:Zmlı:Örnek:Snf:CAP kanser protokolleri Synonyms: Spesmen Süre
zh-CN	Chinese (China)	息肉茎长度:存在与否或特征标识:时间点:标本:名义型:美国病理学家协会癌症方案 Synonyms: CAP 癌症方案;美国病理协会癌症方案一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物存在;存在与否;特征标识;身份;身份标识息肉肉茎长度;息肉肉柄长度;息肉柄长度时刻;随机;随意;瞬间样品样本病理学.方案病理学原始记录病理学方案试样长;长短

85298-8 Body structure included in specimen [Anatomy] in Specimen

Fully-Specified Name

Component: Body structure included in specimen
Property: Anat
Time: Pt
System: Specimen
Scale: Nom
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4310-0

Answer	Code	Score	Answer ID
Cecum			LA16833-8
Ascending colon			LA16834-6
Hepatic flexure			LA16835-3
Transverse colon			LA16836-1
Splenic flexure			LA16837-9
Descending colon			LA16838-7
Sigmoid colon			LA16839-5
Rectosigmoid junction			LA26985-4
Rectum			LA16840-3

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Σωματική δομή περιλαμβάνεται στο δείγμα:Anat:Pt:Δείγμα:Nom: Synonyms: Anat Σωματική δομή περιλαμβάνεται στο δείγμα
es-ES	Spanish (Spain)	estructura del cuerpo incluida en la muestra:Anatatomia:Punto temporal:Especimen:Nom:
es-MX	Spanish (Mexico)	Estructura corporal incluida en la muestra.:Anatomía:Punto temporal:Muestra:Nominal:
it-IT	Italian (Italy)	Parte anatomica inclusa nel campione:Anat:Pt:Campione:Nom: Synonyms: Anatomia Campione Patologia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	lichaamsstructur geïncludeerd in monster:anatomie:moment:monster:nominaal:
zh-CN	Chinese (China)	包括在标本之中的身体结构:解剖学:时间点:标本:名义型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答包括在标本（样本、样品、试样）之中的身体结构受检物时刻;随机;随意;瞬间标本（样本、样品、试样）样品样本物体解剖;解剖结构试样

85348-1 Procedure used to obtain tumor specimen [Type] in Specimen

Fully-Specified Name

Component: Procedure used to obtain tumor specimen
Property: Type
Time: Pt
System: Specimen
Scale: Nom
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4376-1

Answer	Code	Score	Answer ID
Excision without image-guidance localization			LA27207-2
Excision with image-guidance localization			LA27208-0
Total mastectomy (including nipple and skin)			LA27209-8
Colectomy			LA26037-4
Hemicolectomy			LA15410-6
Polypectomy			LA17735-4
Other, Specify:			LA46-8
Not specified			LA27211-4

Member of these Panels

LOINC	Long Common Name
85904-1	Cancer pathology panel - Breast cancer specimen by CAP cancer protocols
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Διαδικασία που χρησιμοποιήθηκε για τη λήψη δείγματος όγκου:Type:Pt:Δείγμα:Nom: Synonyms: Type Διαδικασία Διαδικασία που χρησιμοποιήθηκε για τη λήψη δείγματος όγκου
es-ES	Spanish (Spain)	Procemiento utilizado paraobtener muestra tumoral:Tipo:Punto temporal:Especimen:Nom:
es-MX	Spanish (Mexico)	Procedimiento utilizado para obtener una muestra de tumor:Tipo:Punto temporal:Muestra:Nominal:
it-IT	Italian (Italy)	Procedura usata per ottenere il campione di tumore:Tipo:Pt:Campione:Nom: Synonyms: Campione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	用于获取肿瘤标本的操作项目:类型:时间点:标本:名义型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物型操作;程序;手续;步骤;规程;程序流程时刻;随机;随意;瞬间标本（样本、样品、试样）样品样本用于获取（获得、取得、采集）肿瘤标本（样本、样品、试样）的操作项目（操作）试样

84880-4 Position of rectal tumor in relation to anterior peritoneal reflection [Anatomy] in Tumor

Term Description

For rectal tumors, the relationship of the tumor in relation to the anterior peritoneal reflection may be classified as entirely above, astride (at), or entirely below the level of the anterior peritoneal reflection. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).

Fully-Specified Name

Component: Position of rectal tumor in relation to anterior peritoneal reflection
Property: Anat
Time: Pt
System: Tumor
Scale: Nom
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Order vs. Observation: Observation

Preferred Answer List LL4072-6

Answer	Code	Score	Answer ID
Entirely above			LA26481-4
Astride			LA26482-2
Entirely below			LA26483-0

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Θέση του όγκου του ορθού σε σχέση με την πρόσθια περιτοναϊκή ανάκλαση:Anat:Pt:Όγκος:Nom: Synonyms: Anat Θέση Θέση του όγκου του ορθού σε σχέση με την πρόσθια περιτοναϊκή ανάκλαση
es-ES	Spanish (Spain)	Posición del tumor rectal en relación con el reflejo peritoneal anterior.:Anatatomia:Punto temporal:Tumor:Nom:
es-MX	Spanish (Mexico)	Posición del tumor rectal en relación con el reflejo peritoneal anterior:Anatomía:Punto temporal:Tumor:Nominal:
it-IT	Italian (Italy)	Posizione del tumore rettale in relazione alla riflessione peritoneale anteriore:Anat:Pt:Tumore:Nom: Synonyms: Anatomia Neoplasia Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	直肠肿瘤相对于前腹膜反折的位置:解剖学:时间点:肿瘤:名义型: Synonyms: 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答姿势;体位;职位;职务;地位;身份时刻;随机;随意;瞬间瘤;肿块;赘生物直肠肿瘤相对于前（前部）腹膜反折（转折、折返）的位置解剖;解剖结构

33728-7 Size.maximum dimension in Tumor

Fully-Specified Name

Component: Size.max.dimension
Property: Len
Time: Pt
System: Tumor
Scale: Qn
Method

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.70 (MIN)
Change Reason: Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
98249-6	Cancer pathology panel - Endometrial cancer specimen
81186-9	Gastric cancer pathology panel

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μέγεθος.μέγιστη.διάσταση:Len:Pt:Όγκος:Qn: Synonyms: Len Διαστάσεις Μέγ Μέγεθος Μέγεθος.μέγιστη.διάσταση
es-AR	Spanish (Argentina)	tamaño.máximo.dimensión:longitud:punto en el tiempo:tumor:cuantitativo:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Tamaño.max.dimensión:Longitud:Punto temporal:Tumor:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Size.max.dimension:Largo:Punto temporal:Tumor:Cuantitativo:
it-IT	Italian (Italy)	Dimensione.massima.dimensione:Len:Pt:Tumore:Qn: Synonyms: Lunghezza Massimo Neoplasia Patologia Protocolli patologia - generale Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	afmeting.max.dimensie:afmeting:moment:tumor:kwantitatief: Synonyms: lengte
pt-BR	Portuguese (Brazil)	Tamanho.max.dimensão:Comprimento:Pt:Tumor:Qn:Protocolos de cancer do CAP Synonyms: ; Size.max.dim; Maximum; Maximal; Largest; Peak; Length; Point in time; Random; Quantitative; QNT; Quant; Quan; CAP protocol; PATHOLOGY PROTOCOLS general
ru-RU	Russian (Russian Federation)	Размер.max.измерение:Дл:ТчкВрм:Опухоль:Колич: Synonyms: Длина Количественный Максимум Точка во времени;Момент
tr-TR	Turkish (Turkey)	Büyüklük.maks.boyut:Uzn:Zmlı:Tümör:Kant: Synonyms: Süre
zh-CN	Chinese (China)	大小.最大值.维度:长度:时间点:肿瘤:定量型: Synonyms: 一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通可用数量表示的;定量性;数值型;数量型;连续数值型标尺外形尺寸;外型尺寸;维度;维;大小大小.最大.维度;大小.最大值.尺寸;大小.最大.尺寸尺寸时刻;随机;随意;瞬间最大;极大值病理学.方案病理学原始记录病理学方案瘤;肿块;赘生物长;长短

Example Units

Unit	Source
cm	Example UCUM Units

33729-5 Size additional dimension in Tumor

Fully-Specified Name

Component: Size.additional dimension
Property: Len
Time: Pt
System: Tumor
Scale: Qn
Method

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.70 (MIN)
Change Reason: Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μέγεθος.επιπρόσθετη διάσταση:Len:Pt:Όγκος:Qn: Synonyms: Len Διαστάσεις Μέγεθος Μέγεθος.επιπρόσθετη διάσταση
es-AR	Spanish (Argentina)	tamaño.dimensión adicional:longitud:punto en el tiempo:tumor:cuantitativo:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Tamaño.dimensión adicional:Longitud:Punto temporal:Tumor:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Tamaño dimensión adicional:Largo:Punto temporal:Tumor:Cuantitativo:
it-IT	Italian (Italy)	Dimensione.dimensione addizionale:Len:Pt:Tumore:Qn: Synonyms: Dimensione addizionale di dimensione Lunghezza Neoplasia Patologia Protocolli patologia - generale Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	afmeting.aanvullende dimensie:afmeting:moment:tumor:kwantitatief: Synonyms: lengte
pt-BR	Portuguese (Brazil)	Tamanho.dimensão adicional:Comprimento:Pt:Tumor:Qn:Protocolos de cancer do CAP Synonyms: ; Size add'l dim; Length; Point in time; Random; Quantitative; QNT; Quant; Quan; CAP protocol; Add; PATHOLOGY PROTOCOLS general
ru-RU	Russian (Russian Federation)	Размер.дополнительное измерение:Дл:ТчкВрм:Опухоль:Колич: Synonyms: Длина Количественный Точка во времени;Момент
tr-TR	Turkish (Turkey)	Büyüklük.ek boyut:Uzn:Zmlı:Tümör:Kant: Synonyms: Süre
zh-CN	Chinese (China)	大小.附加维度:长度:时间点:肿瘤:定量型: Synonyms: 一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通可用数量表示的;定量性;数值型;数量型;连续数值型标尺外形尺寸;外型尺寸;维度;维;大小大小.额外尺寸;大小.附加尺寸尺寸时刻;随机;随意;瞬间病理学.方案病理学原始记录病理学方案瘤;肿块;赘生物长;长短附加的额外额外的

Example Units

Unit	Source
cm	Example UCUM Units

84879-6 Tumor perforation [Presence] by Macroscopy

Term Description

The macroscopic finding for the presence or absence of perforation through the tumor. Perforation through the tumor into the peritoneal cavity is a well established adverse prognostic factor in colonic and rectal cancer. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).

Fully-Specified Name

Component: Tumor perforation
Property: PrThr
Time: Pt
System: Tumor
Scale: Ord
Method: Macroscopy

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Order vs. Observation: Observation

Example Answer List LL3950-4

Answer	Code	Score	Answer ID
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value)			LA9633-4
Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value)			LA9634-2

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Διάτρηση όγκου:PrThr:Pt:Όγκος:Ord:Μακροσκοπική εξέταση Synonyms: PrThr Διάτρηση όγκου
es-ES	Spanish (Spain)	Perforación tumoral:PrThr:Punto temporal:Tumor:Ord:Macrosoópico
es-MX	Spanish (Mexico)	Perforación del tumor:Presencia o umbral:Punto temporal:Tumor:Ordinal:Macroscopia
it-IT	Italian (Italy)	Tumore, perforazione:PrThr:Pt:Tumore:Ord:Macroscopia Synonyms: Neoplasia Patologia Perforazione da parte del tumore Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	肿瘤穿孔:存在情况或阈值:时间点:肿瘤:序数型:大体检查 Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间瘤;肿块;赘生物肉眼检查;目视检查;粗视检查;巨观检查;宏观检查;粗略检查;宏观观察术肿瘤穿孔（破裂、洞穿、穿通）

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

33730-3 Resection completeness in Mesorectum Qualitative by Macroscopy

Term Description

This term represents the macroscopic completeness of the surgical mesorectum excision in patients undergoing surgery for rectal cancer. Complete excision, known as total mesorectal excision or TME, is associated with decreased risk of local recurrence and increased rate of 5-year survival. PMID: 27697315

Fully-Specified Name

Component: Resection completeness
Property: Find
Time: Pt
System: Mesorectum
Scale: Ord
Method: Macroscopy

Basic Attributes

Class: PATH.PROTOCOLS.GENER
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.61 (MAJ)
Change Reason: Removed Method of "CAP cancer protocol" and copyright because this is not a CAP-specific concept and added "Method" of macroscopy. Also added an answer list and term description.
Order vs. Observation: Observation

Example Answer List LL4568-3

Answer	Code	Score	Answer ID
Not applicable			LA4720-4
Complete			LA26032-5
Near complete			LA27882-2
Incomplete			LA7341-6
Cannot be determined			LA11899-4

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πληρότητα εκτομής:Εύρεση:Pt:Μεσοορθό:Ord:Μακροσκοπική εξέταση Synonyms: Εύρεση Πληρότητα εκτομής
es-AR	Spanish (Argentina)	integridad de resección:hallazgo:punto en el tiempo:mesorecto:ordinal:protocolos de oncología del CAP
es-ES	Spanish (Spain)	Resección completa:Hallazgo:Punto temporal:Mesorecto:Ord:Macrosoópico
es-MX	Spanish (Mexico)	Completitud de la resección:Hallazgo:Punto temporal:Mesorrecto:Ordinal:Macroscopia
it-IT	Italian (Italy)	Resezione, completezza:Osservazione:Pt:Mesoretto:Ord:Macroscopia Synonyms: Completezza di resezione Osservazione Patologia Protocolli patologia - generale Punto nel tempo (episodio)
pt-BR	Portuguese (Brazil)	Resecção perfeita:Achado:Pt:MesocReto:Ord:Protocolos de cancer do CAP Synonyms: Finding; Findings; Point in time; Random; Ql; Ordinal; QL; Qualitative; Qual; Screen; CAP protocol; PATHOLOGY PROTOCOLS general
zh-CN	Chinese (China)	切除术彻底性:发现:时间点:直肠系膜:序数型:大体检查 Synonyms: 一般病理学原始记录;普通病理学原始记录;病理学.原始记录.普通;病理学.方案.一般;病理学.方案.普通;病理学原始记录.一般;病理学原始记录.普通;病理学方案.一般;病理学方案.普通依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型切除术完整性;切除术完全度;切除术完全性发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论时刻;随机;随意;瞬间病理学.方案病理学原始记录病理学方案直肠上部和骶骨之间的腹膜襞肉眼检查;目视检查;粗视检查;巨观检查;宏观检查;粗略检查;宏观观察术

84882-0 Histologic type in Colorectal cancer specimen by WHO classification

Term Description

Colorectal cancer histologic type based on the current World Health Organization (WHO) classification. Colonrectal tumor types include adenocarcinoma, mucinous adenocarcinoma, signet-ring cell carcinoma, small cell carcinoma, squamous cell carcinoma, adenosquamous carcinoma, medullary carcinoma, and others. [https://publications.iarc.fr/Book-And-Report-Series/Iarc-Handbooks-Of-Cancer-Prevention/Colorectal-Cancer-Screening-2019]

Fully-Specified Name

Component: Histologic type
Property: Type
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: WHO classification

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.72 (MIN)
Change Reason: Release 2.72: DefinitionDescription: updated the url;
Order vs. Observation: Observation

Preferred Answer List LL4073-4

Answer	Code	Score	Answer ID
Adenoma, NOS			LA15390-0
Tubular adenoma, NOS			LA26485-5
Villous adenoma, NOS			LA26486-3
Tubulovillous adenoma, NOS			LA26487-1
Glandular intraepithelial neoplasia, low grade			LA26488-9
Glandular intraepithelial neoplasia, high grade			LA26489-7
Sessile serrated adenoma/polyp			LA26490-5
Serrated polyposis			LA26491-3
Traditional serrated adenoma			LA26492-1
Adenocarcinoma, NOS			LA26493-9
Cribriform comedo-type adenocarcinoma			LA26494-7
Medullary carcinoma, NOS			LA26495-4
Micropapillary carcinoma			LA26496-2
Colloid carcinoma			LA26497-0
Serrated adenocarcinoma			LA26498-8
Signet ring cell carcinoma			LA15444-5
Adenosquamous carcinoma			LA15446-0
Spindle cell carcinoma, NOS			LA26501-9
Undifferentiated carcinoma			LA15447-8
Neuroendocrine tumor G1 (NET G1)/Carcinoid			LA26504-3
Neuroendocrine tumor G2 (NET G2)			LA26505-0
Neuroendocrine carcinoma, NOS			LA26506-8
Large cell neuroendocrine carcinoma			LA26100-0
Small cell neuroendocrine carcinoma			LA26101-8
Mixed adenoneuroendocrine carcinoma			LA26102-6
Enterochromaffin cell (EC), serotonin-producing			LA26510-0
L cell, Glucagon-like peptide-producing and PP/PYY-producing NETs			LA26512-6
Leiomyoma, NOS			LA26513-4
Lipoma, NOS			LA26514-2
Angiosarcoma			LA26515-9
Gastrointestinal stromal tumor, malignant			LA26516-7
Kaposi sarcoma			LA26517-5
Leiomyosarcoma, NOS			LA26518-3
Schwannoma, NOS			LA26519-1
Perineurioma, NOS			LA26520-9
Ganglioneuroma			LA26521-7
Granular cell tumor, NOS			LA26522-5
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)			LA26523-3
Mantle cell lymphoma			LA26524-1
Diffuse large B-cell lymphoma (DLBCL), NOS			LA26525-8
Burkitt lymphoma, NOS			LA26526-6
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma			LA26527-4

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ιστολογικός τύπος:Type:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Ταξινόμηση WHO Synonyms: Type Ιστολογικός τύπος
es-ES	Spanish (Spain)	Tipo histológico:Tipo:Punto temporal:Cáncer colorectal:Nom:Clasificación de la OMS
es-MX	Spanish (Mexico)	Tipo histológico:Tipo:Punto temporal:Muestra de cáncer colorrectal:Nominal:Clasificación de la OMS
it-IT	Italian (Italy)	Tipo istologico:Tipo:Pt:Campione di carcinoma del colon-retto:Nom:OMS, classificazione Synonyms: Campione di tumore Classificazione OMS Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	组织学类型:类型:时间点:结直肠癌标本:名义型:WHO 分类 Synonyms: WHO 分类法;WHO 分类体系;WHO 分类系统;WHO 分型供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物型时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）组织类型;病理类型结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

85281-4 Intratumoral lymphocytic response in Cancer specimen Qualitative by Light microscopy

Fully-Specified Name

Component: Intratumoral lymphocytic response
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4371-2

Answer	Code	Score	Answer ID
None Copyright http://snomed.info/sct ID:260413007 None (qualifier value)			LA137-2
Mild to moderate			LA15008-8
Marked			LA17968-1

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ενδοογκική λεμφοκυτταρική απόκριση:Εύρεση:Pt:Δείγμα καρκίνου:Ord:Μικροσκόπηση.φωτός Synonyms: Ενδοογκική λεμφοκυτταρική απόκριση Εύρεση
es-ES	Spanish (Spain)	respuesta linfocitica intratumoral:Hallazgo:Punto temporal:Muestra de cancer:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Respuesta linfocítica intratumoral:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Risposta linfocitario intratumorale:Osservazione:Pt:Campione tumore:Ord:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
pl-PL	Polish (Poland)	Odpowiedź limfocytarna wewnątrz guza nowotworowego:wynik:punkt w czasie:próbka nowotworu:półilościowy:mikroskopia świetlna
zh-CN	Chinese (China)	肿瘤内部淋巴细胞反应:发现:时间点:癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）肿瘤内淋巴细胞反应;瘤内淋巴细胞反应;ILR 试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85284-8 Peritumoral lymphocytic response in Cancer specimen Qualitative by Light microscopy

Fully-Specified Name

Component: Peritumoral lymphocytic response
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4371-2

Answer	Code	Score	Answer ID
None Copyright http://snomed.info/sct ID:260413007 None (qualifier value)			LA137-2
Mild to moderate			LA15008-8
Marked			LA17968-1

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Περιογκική λεμφοκυτταρική απόκριση:Εύρεση:Pt:Δείγμα καρκίνου:Ord:Μικροσκόπηση.φωτός Synonyms: Εύρεση Περιογκική λεμφοκυτταρική απόκριση
es-ES	Spanish (Spain)	respuesta linfocitica peritumoral:Hallazgo:Punto temporal:Muestra de cancer:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Respuesta linfocítica peritumoral:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Reazione linfocitaria peritumorale:Osservazione:Pt:Campione tumore:Ord:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
pl-PL	Polish (Poland)	Odpowiedź limfocytarna wokół guza nowotworowego:wynik:punkt w czasie:próbka nowotworu:półilościowy:mikroskopia świetlna
zh-CN	Chinese (China)	肿瘤周围淋巴细胞反应:发现:时间点:癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本瘤周淋巴细胞反应;围肿瘤淋巴细胞反应;PLR 癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85282-2 Mucinous fraction [Area Fraction] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Mucinous fraction
Property: AreaFr
Time: Pt
System: Colorectal cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Βλεννώδες κλάσμα:AreaFr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Qn:Μικροσκόπηση.φωτός Synonyms: AreaFr Βλεννώδες κλάσμα
es-ES	Spanish (Spain)	fraccion mucinosa:AreaFr:Punto temporal:Cáncer colorectal:Qn:Microscopía de luz Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Fracción mucinosa:Fracción de área:Punto temporal:Muestra de cáncer colorrectal:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Frazione mucinosa:Frazione di Area:Pt:Campione di carcinoma del colon-retto:Qn:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	黏液性组分:面积分数:时间点:结直肠癌标本:定量型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学分数分数类分级分级分离分部分离分馏分馏（Fractionation）受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）精馏组份（Fraction）组份类组份类（Fractions）组分组分类结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样部分部分类面积小数;面积百分数;面积百分比馏分馏分类黏液性（黏液型、粘液性、粘液型、黏液样、粘液样）组分（部分、成分）

Example Units

Unit	Source
%	Example UCUM Units

84883-8 Deepest extent of tumor invasion [Type] in Colorectal cancer specimen

Term Description

The deepest extent or maximum degree of local tumor invasion into or through the bowel wall. Results are based on the T component of the TNM staging system, as outlined in the AJCC Cancer Staging Manual. PMID: 20180029 Invasion depths include submucosa (pT1), muscularis propria (pT2), through muscularis propria into pericolorectal tissues (pT3), penetrating the visceral peritoneum (pT4a), and directly invading or adherent to other organs or structures (pT4b). This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).

Fully-Specified Name

Component: Deepest extent of tumor invasion
Property: Type
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Change Reason: This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol. In addition, the Scale was corrected from Ord to Nom.
Order vs. Observation: Observation

Preferred Answer List LL4074-2

Answer	Code	Answer ID
Tumor invades submucosa	pT1	LA26528-2
Tumor invades muscularis propria	pT2	LA26529-0
Tumor invades through the muscularis propria into pericolorectal tissues	pT3	LA26530-8
Tumor penetrates the visceral peritoneum	pT4a	LA26531-6
Tumor directly invades or is adherent to other organs or structures	pT4b	LA26532-4

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Βαθύτερη έκταση διήθησης όγκου:Type:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom: Synonyms: Type Βαθύτερη έκταση διήθησης όγκου
es-ES	Spanish (Spain)	Extensión más profunda de la invasión tumoral:Tipo:Punto temporal:Cáncer colorectal:Nom:
es-MX	Spanish (Mexico)	Extensión más profunda de la invasión tumoral:Tipo:Punto temporal:Muestra de cáncer colorrectal:Nominal:
it-IT	Italian (Italy)	Estensione più profonda dell'invasione tumorale:Tipo:Pt:Campione di carcinoma del colon-retto:Nom: Synonyms: Campione di tumore Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	肿瘤侵袭最深范围:类型:时间点:结直肠癌标本:名义型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物型时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本肿瘤侵袭（浸润、侵犯、入侵）最深范围（程度、面积）;肿瘤最深侵袭程度）;肿瘤最大浸润深度试样

85283-0 Organ tumor is adherent to [Anatomy] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Organ tumor is adherent to
Property: Anat
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4370-4

Answer	Code	Score	Answer ID
Coccyx			LA27201-5
Duodenum			LA16846-0
Pancreas			LA4654-5
Stomach			LA4476-3
Urinary bladder			LA9371-1
Uterus			LA4447-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Όργανο στο οποίο είναι προσκολλημένος ο όγκος:Anat:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μικροσκόπηση.φωτός Synonyms: Anat Όργανο στο οποίο είναι προσκολλημένος ο όγκος
es-ES	Spanish (Spain)	tumor adherente a organo:Anatatomia:Punto temporal:Cáncer colorectal:Nom:Microscopía de luz
es-MX	Spanish (Mexico)	El tumor de órgano se adhiere a:Anatomía:Punto temporal:Muestra de cáncer colorrectal:Nominal:Microscopía óptica
it-IT	Italian (Italy)	Tumore d'organo aderente a:Anat:Pt:Campione di carcinoma del colon-retto:Nom:Microscopia.ottica Synonyms: Anatomia Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	器官肿瘤粘附于:解剖学:时间点:结直肠癌标本:名义型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物器官肿瘤粘附（黏附、附着、粘连、黏着）于时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本解剖;解剖结构试样

85275-6 Adjacent structure invaded by tumor [Anatomy] in Colorectal cancer specimen by Light microscopy

Part Descriptions

LP247832-1 Adjacent structure invaded by tumor
The organ or other body structure invaded by a tumor. For example, breast tumors can invade the chest wall, skeletal muscle and skin, and colon cancer can invade many organs or structures, including the pancreas, urinary bladder, ovary, uterus, and coccyx. Source: Regenstrief LOINC

Fully-Specified Name

Component: Adjacent structure invaded by tumor
Property: Anat
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Microscopy.light

Basic Attributes

Class: PATH.HISTO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4370-4

Answer	Code	Score	Answer ID
Coccyx			LA27201-5
Duodenum			LA16846-0
Pancreas			LA4654-5
Stomach			LA4476-3
Urinary bladder			LA9371-1
Uterus			LA4447-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Παρακείμενη δομή με εισβολή του όγκου:Anat:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μικροσκόπηση.φωτός Synonyms: Anat Παρακείμενη δομή με εισβολή του όγκου
es-ES	Spanish (Spain)	Estructura adyacente invadida por el tumor:Anatatomia:Punto temporal:Cáncer colorectal:Nom:Microscopía de luz Synonyms: Histologia
es-MX	Spanish (Mexico)	Estructura adyacente invadida por tumor:Anatomía:Punto temporal:Muestra de cáncer colorrectal:Nominal:Microscopía óptica
it-IT	Italian (Italy)	Struttura adiacente invasa dal tumore:Anat:Pt:Campione di carcinoma del colon-retto:Nom:Microscopia.ottica Synonyms: Anatomia Campione di tumore Istologia Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	肿瘤所侵犯的邻近结构:解剖学:时间点:结直肠癌标本:名义型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）组织学结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本肿瘤所侵犯的邻近（相邻、近邻、紧邻）结构解剖;解剖结构试样

85290-5 Surgical margin tumor involvement [Presence] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Surgical margin tumor involvement
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4381-1

Answer	Code	Score	Answer ID
Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding)			LA27250-2
Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding)			LA27251-0
Cannot be assessed			LA27144-7

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Συμμετοχή εγχειρητικού ορίου όγκου
es-ES	Spanish (Spain)	afetación tumoral del margen quirúrgico:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	手术边缘肿瘤累及:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）手术边缘（手术切缘、切缘）肿瘤累及时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85276-4 Closest surgical margin when all margins are uninvolved [Type] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Closest surgical margin when all margins are uninvolved
Property: Type
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4348-0

Answer	Code	Score	Answer ID
Proximal margin			LA27145-4
Distal margin			LA27149-6
Deep margin			LA27146-2
Circumferential margin			LA27147-0
Mucosal margin			LA27150-4
Mesenteric margin			LA27148-8
Other, Specify:			LA46-8

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πλησιέστερο εγχειρητικό περιθώριο όταν δεν εμπλέκεται κανένα όριο:Type:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μικροσκόπηση.φωτός Synonyms: Type Πλησιέστερο εγχειρητικό περιθώριο όταν δεν εμπλέκεται κανένα όριο
es-ES	Spanish (Spain)	Margen quirúrgico más cercano cuando todos los márgenes no están involucrados:Tipo:Punto temporal:Cáncer colorectal:Nom:Microscopía de luz
es-MX	Spanish (Mexico)	Margen quirúrgico más cercano cuando todos los márgenes no están afectados:Tipo:Punto temporal:Muestra de cáncer colorrectal:Nominal:Microscopía óptica
it-IT	Italian (Italy)	Margine di resezione chirurgica più vicino quando tutti i margini sono dissecati:Tipo:Pt:Campione di carcinoma del colon-retto:Nom:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	并未累及所有边缘时的最近手术边缘:类型:时间点:结直肠癌标本:名义型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物型并未累及所有（全部）边缘时的最近手术边缘（手术切缘、切缘）时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

85278-0 Distance of carcinoma from closest surgical margin when all margins are uninvolved [Length] in Cancer specimen by Light microscopy

Fully-Specified Name

Component: Distance of carcinoma from closest surgical margin when all margins are uninvolved
Property: Len
Time: Pt
System: Cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Απόσταση του καρκινώματος από το πλησιέστερο εγχειρητικό όριο όταν δεν εμπλέκεται κανένα όριο:Len:Pt:Δείγμα καρκίνου:Qn:Μικροσκόπηση.φωτός Synonyms: Len Απόσταση του καρκινώματος από το πλησιέστερο εγχειρητικό όριο όταν δεν εμπλέκεται κανένα όριο Πλησιέστερο εγχειρητικό περιθώριο όταν δεν εμπλέκεται κανένα όριο
es-ES	Spanish (Spain)	Distancia del carcinoma al margen quirurgico mas próximo cuando todos los margenes no estan afectados:Longitud:Punto temporal:Muestra de cancer:Qn:Microscopía de luz Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Distancia del carcinoma desde el margen quirúrgico más cercano cuando todos los márgenes no están afectados:Largo:Punto temporal:Espécimen de cáncer:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Distanza del carcinoma dal margine chirurgico più vicino quando tutti i margini non sono coinvolti:Len:Pt:Campione tumore:Qn:Microscopia.ottica Synonyms: Campione di tumore Lunghezza Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	当并未累及所有边缘时癌相距最近手术边缘的距离:长度:时间点:癌标本:定量型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺并未累及所有（全部）边缘时的最近手术边缘（手术切缘、切缘）当并未累及所有（全部）边缘时癌相距（距离、至、到）最近手术边缘（手术切缘、切缘）的距离时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样长;长短

Example Units

Unit	Source
mm	Example UCUM Units

85295-4 Surgical margin tumor involvement.proximal [Presence] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Surgical margin tumor involvement.proximal
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4381-1

Answer	Code	Score	Answer ID
Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding)			LA27250-2
Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding)			LA27251-0
Cannot be assessed			LA27144-7

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου.εγγύς:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.εγγύς
es-ES	Spanish (Spain)	Margen quirúrgico afectado del tumor. Proximal:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico proximal:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore.prossimale:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.prossi Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	外科手术边界肿瘤累及.近端:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物外科手术边缘肿瘤累及.近端;手术边界肿瘤累及.近端;外科手术边界肿瘤累及.近侧;外科手术边界肿瘤累及.近身体中心;外科手术边界肿瘤累及.近邻存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）手术边缘（手术切缘、切缘）肿瘤累及时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85292-1 Surgical margin tumor involvement.distant [Presence] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Surgical margin tumor involvement.distant
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4381-1

Answer	Code	Score	Answer ID
Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding)			LA27250-2
Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding)			LA27251-0
Cannot be assessed			LA27144-7

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου.απομακρυσμένο:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.απομακρυσμένο
es-ES	Spanish (Spain)	Margen quirúrgico afectado del tumor.Distante:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico distante:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore.distante:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.distan Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	外科手术边界肿瘤累及.远处:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物外科手术边缘肿瘤累及.远处;手术边界肿瘤累及.远隔;外科手术边界肿瘤累及.远距存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）手术边缘（手术切缘、切缘）肿瘤累及时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

84885-3 Surgical margin tumor involvement.circumferential [Presence] in Colorectal cancer specimen

Term Description

The result for whether or not the circumferential resection margin (CRM) on the non-peritonealized surface of the resected specimen is involved. CRM involvement (1mm or less distance between tumor and CRM) is an important predictor of local recurrence in rectal carcinoma. PMID: 16328130 This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).

Fully-Specified Name

Component: Surgical margin tumor involvement.circumferential
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Change Reason: This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
Order vs. Observation: Observation

Example Answer List LL4076-7

Answer	Code	Score	Answer ID
Involved			LA26536-5
Not involved			LA26535-7

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου.περιμετρικό:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord: Synonyms: PrThr Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.περιμετρικό
es-ES	Spanish (Spain)	Margen quirúrgico afectado del tumor.Circunferencial:PrThr:Punto temporal:Cáncer colorectal:Ord:
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico circunferencial:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore.circonferenziale:PrThr:Pt:Campione di carcinoma del colon-retto:Ord: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.circon Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	外科手术边界肿瘤累及.周围:存在情况或阈值:时间点:结直肠癌标本:序数型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型受检物外科手术边缘肿瘤累及.周围;手术边界肿瘤累及.周缘;外科手术边界肿瘤累及.周界;外科手术边界肿瘤累及.四界存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）手术边缘（手术切缘、切缘）肿瘤累及时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

85293-9 Surgical margin tumor involvement.mesenteric [Presence] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Surgical margin tumor involvement.mesenteric
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4381-1

Answer	Code	Score	Answer ID
Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding)			LA27250-2
Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding)			LA27251-0
Cannot be assessed			LA27144-7

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου.μεσεντέριο:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.μεσεντέριο
es-ES	Spanish (Spain)	afectacion tumoral del margen quirúrgico mesenterico:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico mesentérico:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore.mesenterico:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.mesent Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	手术边缘肿瘤累及.肠系膜:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）手术边缘（手术切缘、切缘）肿瘤累及手术边缘（手术切缘、切缘）肿瘤累及.肠系膜时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85291-3 Surgical margin tumor involvement.deep [Presence] in Colorectal cancer specimen by Light microscopy

Part Descriptions

LP73459-7 Surgical margin tumor involvement.deep
Biopsies of the skin are done in order to remove skin lesions and determine the specific diagnosis. Surgical margins are the boundaries of the excised specimen, and in the case of a skin biopsy, the deep margin is the one furthest away from the skin surface. A margin is considered 'positive' if it contains neoplastic cells and indicates that additional treatment may be needed besides the excision. Deeper excisions are more invasive but are associated with diminished chances for the tumor's reoccurrence. PMID: 25484385 Source: Regenstrief LOINC

Fully-Specified Name

Component: Surgical margin tumor involvement.deep
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4381-1

Answer	Code	Score	Answer ID
Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding)			LA27250-2
Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding)			LA27251-0
Cannot be assessed			LA27144-7

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου.εν τω βάθει:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.εν τω βάθει
es-ES	Spanish (Spain)	Margen quirúrgico afectado del tumor.Profundidad:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico profundo:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore.profondo:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.profon Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	外科手术边界肿瘤累及.深部:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物外科手术边缘肿瘤累及.深部;手术边界肿瘤累及.深部存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）手术边缘（手术切缘、切缘）肿瘤累及时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85294-7 Surgical margin tumor involvement.mucosal [Identifier] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Surgical margin tumor involvement.mucosal
Property: Prid
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4350-6

Answer	Code	Score	Answer ID
Cannot be assessed			LA27144-7
Uninvolved by invasive carcinoma			LA27151-2
Involved by invasive carcinoma			LA27152-0
Uninvolved by adenoma			LA27153-8
Involved by adenoma			LA27154-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Συμμετοχή εγχειρητικού ορίου όγκου.βλεννογόνου:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μικροσκόπηση.φωτός Synonyms: Prid Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.βλεννογόνου
es-ES	Spanish (Spain)	Margen quirúrgico afectado del tumor. Mucosa:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Microscopía de luz
es-MX	Spanish (Mexico)	Afectación tumoral del margen quirúrgico mucosa:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Microscopía óptica
it-IT	Italian (Italy)	Coinvolgimento margine chirurgico tumore.mucosale:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Microscopia.ottica Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.mucosa Microscopia ottica Neoplasia maligna Patologia Presenza o Identità Punto nel tempo (episodio)
zh-CN	Chinese (China)	外科手术边界肿瘤累及.粘膜:存在与否或特征标识:时间点:结直肠癌标本:名义型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物外科手术边缘肿瘤累及.粘膜;手术边界肿瘤累及.粘膜;外科手术边界肿瘤累及.黏膜存在;存在与否;特征标识;身份;身份标识手术边缘（手术切缘、切缘）肿瘤累及时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

85277-2 Distance of carcinoma from closest mucosal margin when all mucosal margins are uninvolved [Length] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Distance of carcinoma from closest mucosal margin when all mucosal margins are uninvolved
Property: Len
Time: Pt
System: Colorectal cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Απόσταση του καρκινώματος από το πλησιέστερο όριο του βλεννογόνου όταν δεν εμπλέκεται κανένα όριο του βλεννογόνου:Len:Pt:Δείγμα καρκίνου του παχέος εντέρου:Qn:Μικροσκόπηση.φωτός Synonyms: Len Απόσταση του καρκινώματος από το πλησιέστερο όριο του βλεννογόνου όταν δεν εμπλέκεται κανένα όριο του βλεννογόνου
es-ES	Spanish (Spain)	Distancia del carcinoma al margen mucoso mas próximo cuando todos los margenes no estan afectados:Longitud:Punto temporal:Cáncer colorectal:Qn:Microscopía de luz Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Distancia del carcinoma al margen de la mucosa más cercano cuando todos los márgenes de la mucosa no están afectados:Largo:Punto temporal:Muestra de cáncer colorrectal:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Distanza di carcinoma dal margine più vicino della mucosa quando tutti margini della mucosa non sono coinvolti:Len:Pt:Campione di carcinoma del colon-retto:Qn:Microscopia.ottica Synonyms: Campione di tumore Lunghezza Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	当并未累及所有黏膜边缘时癌相距最近黏膜边缘的距离:长度:时间点:结直肠癌标本:定量型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺当并未累及所有（全部）黏膜（粘膜）边缘时癌相距（距离、至、到）最近黏膜（粘膜）边缘的距离时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样长;长短

Example Units

Unit	Source
mm	Example UCUM Units

85288-9 Radial position of closest uninvolved mucosal margin [Angle] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Radial position of closest mucosal margin when mucosal margin uninvolved by invasive carcinoma
Property: Angle
Time: Pt
System: Colorectal cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH.HISTO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ακτινική θέση του πλησιέστερου ορίου του βλεννογόνου όταν το όριο του βλεννογόνου δε συμμετέχει στο διηθητικό καρκίνωμα:Γωνία:Pt:Δείγμα καρκίνου του παχέος εντέρου:Qn:Μικροσκόπηση.φωτός Synonyms: Ακτινική θέση του πλησιέστερου ορίου του βλεννογόνου όταν το όριο του βλεννογόνου δε συμμετέχει στο διηθητικό καρκίνωμα Γωνία Θέση
es-ES	Spanish (Spain)	Posición radial del margen mucoso más cercano cuando el margen mucoso no está afectado por carcinoma invasivo:Ángulo:Punto temporal:Cáncer colorectal:Qn:Microscopía de luz Synonyms: Cuantitativo Histologia
es-MX	Spanish (Mexico)	Posición radial del margen mucoso no afectado más cercano:Ángulo:Punto temporal:Muestra de cáncer colorrectal:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Posizione radiale del margine mucosale più vicino quando il margine mucosale non è interessato dal carcinoma invasivo:Angolo:Pt:Campione di carcinoma del colon-retto:Qn:Microscopia.ottica Synonyms: Campione di tumore Istologia Microscopia ottica Neoplasia maligna Patologia Posizione radiale del margine mucosale più vicino Punto nel tempo (episodio)
zh-CN	Chinese (China)	当浸润性癌并未累及黏膜边缘时最近黏膜边缘的径向位置:角度:时间点:结直肠癌标本:定量型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学几何学角度;几何角度受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺姿势;体位;职位;职务;地位;身份当浸润性癌（浸润性癌症、浸润癌、侵袭性癌、侵袭性癌症）并未累及黏膜（粘膜）边缘时最近黏膜（粘膜）边缘的径向位置时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）组织学结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Example Units

Unit	Source
deg	Example UCUM Units

85287-1 Radial position of closest mucosal margin involved by invasive carcinoma [Angle] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Radial position of closest mucosal margin involved by invasive carcinoma
Property: Angle
Time: Pt
System: Colorectal cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH.HISTO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ακτινική θέση του πλησιέστερου ορίου βλεννογόνου που συμμετέχει στο διηθητικό καρκίνωμα:Γωνία:Pt:Δείγμα καρκίνου του παχέος εντέρου:Qn:Μικροσκόπηση.φωτός Synonyms: Ακτινική θέση του πλησιέστερου ορίου βλεννογόνου που συμμετέχει στο διηθητικό καρκίνωμα Γωνία Θέση
es-ES	Spanish (Spain)	Posición radial del margen mucoso más cercano involucrado por carcinoma invasivo:Ángulo:Punto temporal:Cáncer colorectal:Qn:Microscopía de luz Synonyms: Cuantitativo Histologia
es-MX	Spanish (Mexico)	Posición radial del margen mucoso más cercano involucrado por carcinoma invasivo:Ángulo:Punto temporal:Muestra de cáncer colorrectal:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Posizione radiale del margine mucosale più vicino interessato dal carcinoma invasivo:Angolo:Pt:Campione di carcinoma del colon-retto:Qn:Microscopia.ottica Synonyms: Campione di tumore Istologia Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	当浸润性癌累及黏膜边缘时最近黏膜边缘的径向位置:角度:时间点:结直肠癌标本:定量型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学几何学角度;几何角度受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺姿势;体位;职位;职务;地位;身份当浸润性癌（浸润性癌症、浸润癌、侵袭性癌、侵袭性癌症）累及黏膜（粘膜）边缘时最近黏膜（粘膜）边缘的径向位置时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）组织学结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Example Units

Unit	Source
deg	Example UCUM Units

85289-7 Signet ring cells/cells in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Signet ring cells/Cells
Property: NFr
Time: Pt
System: Colorectal cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.79 (NAM)
Change Reason: Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Κύτταρα δίκην σφραγιστήρος δακτυλίου/κύτταρα:NFr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Qn:Μικροσκόπηση.φωτός Synonyms: NFr Κύτταρα Κύτταρα δίκην σφραγιστήρος δακτυλίου
es-ES	Spanish (Spain)	celulas en anillo de sello/células:Fracción numérica:Punto temporal:Cáncer colorectal:Qn:Microscopía de luz Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Células en anillo de sello / 100 células:Fracción numérica:Punto temporal:Muestra de cáncer colorrectal:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Cellule anello con sigillo/cellule:NFr:Pt:Campione di carcinoma del colon-retto:Qn:Microscopia.ottica Synonyms: Campione di tumore Frazione numerica Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	印戒细胞/细胞:计数型分数:时间点:结直肠癌标本:定量型:显微镜检查.光学 Synonyms: SRC;戒指状细胞;戒指样细胞;印指环状细胞;图章戒指状细胞供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）细胞含量;细胞性;细胞性质;细胞构成;细胞类结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Example Units

Unit	Source
%	Example UCUM Units

85296-2 Tumor budding [Presence] in Cancer specimen by Light microscopy

Part Descriptions

LP247844-6 Tumor budding
Tumor budding is the presence of single cells or clusters of less than five cells scattered in the stroma at the margin of an invasive tumor. Tumor budding may be a predictor of regional lymph node involvement and is associated with worse outcomes, including cancer recurrence, in patients with colorectal cancer. PMID: 22669453 Source: Regenstrief LOINC

Fully-Specified Name

Component: Tumor budding
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL744-4

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Εκβλάστηση όγκου:PrThr:Pt:Δείγμα καρκίνου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Εκβλάστηση όγκου
es-ES	Spanish (Spain)	"yemas " tumorales:PrThr:Punto temporal:Muestra de cancer:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Brote del tumor:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Tumor budding:PrThr:Pt:Campione tumore:Ord:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	肿瘤出芽:存在情况或阈值:时间点:癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）肿瘤芽殖;肿瘤出芽生长;瘤芽试样

85297-0 Tumor buds [#/area] in Cancer specimen by Light microscopy

Part Descriptions

LP247845-3 Tumor buds
Tumor budding is the presence of single cells or clusters of less than five cells scattered in the stroma at the margin of an invasive tumor. Tumor budding may be a predictor of regional lymph node involvement and is associated with worse outcomes, including cancer recurrence, in patients with colorectal cancer. PMID: 22669453 Source: Regenstrief LOINC

Fully-Specified Name

Component: Tumor buds
Property: Naric
Time: Pt
System: Cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Καρκινικές εκβλαστήσεις:Naric:Pt:Δείγμα καρκίνου:Qn:Μικροσκόπηση.φωτός Synonyms: Naric Καρκινικές εκβλαστήσεις
es-ES	Spanish (Spain)	"yemas" de tumor:Número aréico (por área):Punto temporal:Muestra de cancer:Qn:Microscopía de luz Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Brotes tumorales:Número -área:Punto temporal:Espécimen de cáncer:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Tumor buds:Naric:Pt:Campione tumore:Qn:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Numero Areico (per area) Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	肿瘤芽:单位面积数量或计数:时间点:癌标本:定量型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学单位面积的数量;单位面积的计数;计数/数量受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本瘤芽;肿瘤芽胞癌癌（癌症、癌变）标本（样本、样品、试样）试样

Example Units

Unit	Source
/[HPF]	Example UCUM Units

21894-1 Regional lymph nodes examined [#] Specimen

Term Description

Records the total number of regional lymph nodes that were removed and examined by the pathologist. Beginning with tumors diagnosed on or after January 1, 2004, this item is a component of the Collaborative Stage system. Tumors diagnosed from 1988 through 2003, this item is a part of the 10-digit EOD [779], detailed site-specific codes for anatomic EOD.

This data item serves as a quality measure of the pathologic and surgical evaluation and treatment of the patient... NAACCR Data Standards and Data Dictionary Version 11

Fully-Specified Name

Component: Regional lymph nodes examined
Property: Num
Time: Pt
System: Specimen
Scale: Qn
Method

Basic Attributes

Class: TUMRRGT
Type: Clinical
First Released: Version 1.0m
Last Updated: Version 2.56 (MAJ)
Change Reason: Changed the system from "Cancer.XXX" to "Specimen".

Member of these Panels

LOINC	Long Common Name
85904-1	Cancer pathology panel - Breast cancer specimen by CAP cancer protocols
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81186-9	Gastric cancer pathology panel
49083-9	North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 11 panel
59852-4	North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 12 panel
74293-2	Oncology plan of care and summary - recommended CDA set

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Εξετασθέντες περιφερικοί λεμφαδένες:Αρ.:Pt:Δείγμα:Qn: Synonyms: Αρ.
es-AR	Spanish (Argentina)	ganglios linfáticos regionales examinados:número:punto en el tiempo:cáncer.XXX:cuantitativo:
es-ES	Spanish (Spain)	Nodos linfáticos regionales examinados:Número (recuento):Punto temporal:Especimen:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Examen de los ganglios linfáticos regionales:Num:Punto temporal:Muestra:Cuantitativo:
it-IT	Italian (Italy)	Linfonodi regionali esaminati:Num:Pt:Campione:Qn: Synonyms: Numero (conta) Punto nel tempo (episodio) Registro tumori
ru-RU	Russian (Russian Federation)	Региональные лимфоузлы исследованы:Кол:ТчкВрм:Образец:Колич: Synonyms: Количественный Количество порция;образец;материал для анализа Точка во времени;Момент
tr-TR	Turkish (Turkey)	İncelenmiş bölgesel lenf nodları:Say:Zmlı:Örnek:Kant: Synonyms: Spesmen
zh-CN	Chinese (China)	已检查的局部淋巴结:数量(计数):时间点:标本:定量型: Synonyms: NAACCR 肿瘤登记;癌症登记中心北美协会肿瘤登记;肿瘤注册;肿瘤登记（NAACCR）;肿瘤登记（癌症登记中心北美协会）;癌症登记中心北美协会;North American Association of Central Cancer Registries;NAACCR 个数;数量;数量或计数（非负整数）;计数供检查用的材料;待检物;待试验物;样品;样本;试料;试样受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺已检查（已检查过、已查过、所检查、所检查过）的局部淋巴结;已检查的区域淋巴结已检查（已检查过、已查过、所检查、所检查过）的淋巴结;已检查淋巴结的数量时刻;随机;随意;瞬间样品样本试样

Example Units

Unit	Source
{#}	Example UCUM Units

Related Codes

Code System	Code	Code Text	Code Version
NAACCR_ID	830

21893-3 Regional lymph nodes positive [#] Specimen

Term Description

Records the exact number of regional nodes examined by the pathologist and found to contain metastases. Beginning with tumors diagnosed on or after January 1, 2004, this item is a component of the Collaborative Stage system. Tumors diagnosed from 1988 through 2003,this item is part of the 10-digit EOD [779], detailed site-specific codes for anatomic EOD.

This data item is necessary for pathologic staging, and it serves as a quality measure for pathology reports and the extent of the surgical evaluation and treatment of the patient. NAACCR Data Standards and Data Dictionary Version 11

Fully-Specified Name

Component: Regional lymph nodes positive
Property: Num
Time: Pt
System: Specimen
Scale: Qn
Method

Basic Attributes

Class: TUMRRGT
Type: Clinical
First Released: Version 1.0m
Last Updated: Version 2.61 (MIN)
Change Reason: Changed the system from "Cancer.XXX" to "Specimen".

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81186-9	Gastric cancer pathology panel
49083-9	North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 11 panel
59852-4	North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 12 panel

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Θετικοί περιφερικοί λεμφαδένες:Αρ.:Pt:Δείγμα:Qn: Synonyms: Αρ.
es-AR	Spanish (Argentina)	ganglios linfáticos regionales positivos:número:punto en el tiempo:cáncer.XXX:cuantitativo:
es-ES	Spanish (Spain)	Nodos linfáticos regionales positivos:Número (recuento):Punto temporal:Especimen:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Ganglios linfáticos regionales positivos:Num:Punto temporal:Muestra:Cuantitativo:
it-IT	Italian (Italy)	Linfonodi regionali positivi:Num:Pt:Campione:Qn: Synonyms: Numero (conta) Punto nel tempo (episodio) Registro tumori
ru-RU	Russian (Russian Federation)	Региональные лимфоузлы положительный:Кол:ТчкВрм:Образец:Колич: Synonyms: Количественный Количество порция;образец;материал для анализа Точка во времени;Момент
zh-CN	Chinese (China)	局部淋巴结阳性:数量(计数):时间点:标本:定量型: Synonyms: NAACCR 肿瘤登记;癌症登记中心北美协会肿瘤登记;肿瘤注册;肿瘤登记（NAACCR）;肿瘤登记（癌症登记中心北美协会）;癌症登记中心北美协会;North American Association of Central Cancer Registries;NAACCR 个数;数量;数量或计数（非负整数）;计数供检查用的材料;待检物;待试验物;样品;样本;试料;试样区域淋巴结阳性;阳性局部淋巴结受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间样品样本结果阳性试样试验阳性试验阳性的阳性结果

Example Units

Unit	Source
{#}	Example UCUM Units

Related Codes

Code System	Code	Code Text	Code Version
NAACCR_ID	820

84888-7 Intramural vein invasion [Presence] in Colorectal cancer specimen by Light microscopy

Part Descriptions

LP222091-3 Intramural vein invasion
Venous invasion (VI) is a well-established prognostic indicator in colorectal cancers and associated with an increase in risk of distant metastases. PMID: 26933769 VI can be classified as either intramural venous invasion (IMVI) or extramural venous invasion (EMVI). IMVI is when a tumor cells are confined to veins within the bowel wall. EMVI is when tumor cells are present in veins outside the bowel wall. Either one or both may be present. The presence of EMVI is a strong predictor of adverse outcome. PMCID: PMC4283716 Source: Regenstrief LOINC

Fully-Specified Name

Component: Intramural vein invasion
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Change Reason: This term is still in Trial status and upon further review, we added "Microscopy.light" as method to align with similar terms and since this cancer pathology observation is detected by light microscopy.
Order vs. Observation: Observation

Example Answer List LL748-5

Answer	Code	Score	Answer ID
Not identified			LA11902-6
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value)			LA9633-4

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ενδοτοιχωματική φλεβική διήθηση:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Ενδοτοιχωματική φλεβική διήθηση
es-ES	Spanish (Spain)	Invasión venosa intramural:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Invasión de venas intramurales:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Invasione vena intramurale:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	壁内静脉侵袭:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物壁内静脉侵袭（浸润、侵犯、入侵）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

84889-5 Extramural vein invasion [Presence] in Colorectal cancer specimen by Light microscopy

Part Descriptions

LP222092-1 Extramural vein invasion
Venous invasion (VI) is a well-established prognostic indicator in colorectal cancers and associated with an increase in risk of distant metastases. PMID: 26933769 VI can be classified as either intramural venous invasion (IMVI) or extramural venous invasion (EMVI). IMVI is when a tumor cells are confined to veins within the bowel wall. EMVI is when tumor cells are present in veins outside the bowel wall. Either one or both may be present. The presence of EMVI is a strong predictor of adverse outcome. PMCID: PMC4283716 Source: Regenstrief LOINC

Fully-Specified Name

Component: Extramural vein invasion
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Change Reason: This term is still in Trial status and upon further review, we added "Microscopy.light" as method to align with similar terms and since this cancer pathology observation is detected by light microscopy.
Order vs. Observation: Observation

Example Answer List LL748-5

Answer	Code	Score	Answer ID
Not identified			LA11902-6
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value)			LA9633-4

Member of these Panels

LOINC	Long Common Name
84907-5	Cancer pathology panel - Colorectal cancer specimen
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Εξωτοιχωματική φλεβική διήθηση:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord:Μικροσκόπηση.φωτός Synonyms: PrThr Εξωτοιχωματική φλεβική διήθηση
es-ES	Spanish (Spain)	Invasión venosa extramural:PrThr:Punto temporal:Cáncer colorectal:Ord:Microscopía de luz
es-MX	Spanish (Mexico)	Invasión de venas extramurales:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:Microscopía óptica
it-IT	Italian (Italy)	Invasione extramurale della vena:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	壁外静脉侵袭:存在情况或阈值:时间点:结直肠癌标本:序数型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学受检物壁外静脉侵袭（浸润、侵犯、入侵）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

92837-4 Perineural invasion [Presence] in Cancer specimen

Fully-Specified Name

Component: Perineural invasion
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.66
Last Updated: Version 2.66 (ADD)
Order vs. Observation: Observation

Example Answer List LL1937-3

Answer	Code	Score	Answer ID
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value)			LA9633-4
Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value)			LA9634-2

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81186-9	Gastric cancer pathology panel

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Περινευρική διήθηση:PrThr:Pt:Δείγμα καρκίνου:Ord: Synonyms: PrThr Περινευρική διήθηση
es-ES	Spanish (Spain)	Invasión perineural:PrThr:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Invasión perineural:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Invasione perineurale:PrThr:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	神经周围侵袭:存在情况或阈值:时间点:癌标本:序数型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）神经周围侵袭（浸润、侵犯、入侵）;神经周侵袭;围神经侵袭试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

84886-1 Satellite nodules [Presence] in Colorectal cancer specimen

Term Description

The presence or absence of isolated satellite nodules (extramural tumor deposits) within the mesocolic and mesorectal fat. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).

Part Descriptions

LP222090-5 Satellite nodules
A satellite nodule is a cluster of neoplastic cells that are less than 2cm from the primary tumor. [NCBI Books: NBK65951] Source: Regenstrief LOINC

Fully-Specified Name

Component: Satellite nodules
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.69 (MIN)
Change Reason: This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
Order vs. Observation: Observation

Example Answer List LL3950-4

Answer	Code	Score	Answer ID
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value)			LA9633-4
Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value)			LA9634-2

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δορυφορικά οζίδια:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord: Synonyms: PrThr Δορυφορικά οζίδια
es-ES	Spanish (Spain)	Nódulos satélites:PrThr:Punto temporal:Cáncer colorectal:Ord:
es-MX	Spanish (Mexico)	Nódulos satélite:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:
it-IT	Italian (Italy)	Noduli satelliti:PrThr:Pt:Campione di carcinoma del colon-retto:Ord: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	卫星结节:存在情况或阈值:时间点:结直肠癌标本:序数型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型卫星病灶;微小病灶;孤立结节;孤立卫星结节;isolated satellite nodules (extramural tumor deposits);孤立卫星结节（壁外肿瘤种植）受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85508-0 Satellite nodules [#] in Colorectal cancer specimen by Light microscopy

Part Descriptions

LP222090-5 Satellite nodules
A satellite nodule is a cluster of neoplastic cells that are less than 2cm from the primary tumor. [NCBI Books: NBK65951] Source: Regenstrief LOINC

Fully-Specified Name

Component: Satellite nodules
Property: Num
Time: Pt
System: Colorectal cancer specimen
Scale: Qn
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δορυφορικά οζίδια:Αρ.:Pt:Δείγμα καρκίνου του παχέος εντέρου:Qn:Μικροσκόπηση.φωτός Synonyms: Αρ. Δορυφορικά οζίδια
es-ES	Spanish (Spain)	Nódulos satélites:Número (recuento):Punto temporal:Cáncer colorectal:Qn:Microscopía de luz Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Nódulos satélite:Número (recuento):Punto temporal:Muestra de cáncer colorrectal:Cuantitativo:Microscopía óptica
it-IT	Italian (Italy)	Noduli satelliti:Num:Pt:Campione di carcinoma del colon-retto:Qn:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	卫星结节:数量(计数):时间点:结直肠癌标本:定量型:显微镜检查.光学 Synonyms: 个数;数量;数量或计数（非负整数）;计数供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学卫星病灶;微小病灶;孤立结节;孤立卫星结节;isolated satellite nodules (extramural tumor deposits);孤立卫星结节（壁外肿瘤种植）受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Example Units

Unit	Source
{#}	Example UCUM Units

84891-1 Tumor response to neoadjuvant therapy

Term Description

The response of the tumor to neoadjuvant treatment, such as chemotherapy and radiotherapy. Chemotherapy and/or radiotherapy before resection is associated with significant downstaging and improved prognosis. These specimens require close gross examination and additional blocking to demonstrate tumor. The degree of tumor regression has been shown to correlate with prognosis. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).

Fully-Specified Name

Component: Response to neoadjuvant therapy
Property: PrThr
Time: Pt
System: Colorectal cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.71 (MIN)
Change Reason: This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
Order vs. Observation: Observation

Example Answer List LL4077-5

Answer	Code	Score	Answer ID
No prior treatment			LA26537-3
Complete response (Grade 0 - No viable cancer cells)			LA26538-1
Moderate response (Grade 1 - Single cells or small groups of cancer cells)			LA26539-9
Mminimal response (Grade 2 - Residual cancer outgrown by fibrosis)			LA26540-7
Poor response (Grade 3 - Minimal or no tumor kill; extensive)			LA26541-5

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ανταπόκριση στη νεοεπικουρική θεραπεία:PrThr:Pt:Δείγμα καρκίνου του παχέος εντέρου:Ord: Synonyms: PrThr Ανταπόκριση στη νεοεπικουρική θεραπεία
es-ES	Spanish (Spain)	Respuesta a la terapia neoadyuvante:PrThr:Punto temporal:Cáncer colorectal:Ord:
es-MX	Spanish (Mexico)	Respuesta a la terapia neoadyuvante:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:
it-IT	Italian (Italy)	Risposta a terapia neoadiuvante:PrThr:Pt:Campione di carcinoma del colon-retto:Ord: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	对新辅助疗法的反应:存在情况或阈值:时间点:结直肠癌标本:序数型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）对新辅助疗法（新辅助治疗）的反应（响应、应答）;新辅助疗法（新辅助治疗）的效果时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

85285-5 Polyp in which invasive carcinoma arose [Type] in Colorectal cancer specimen by Light microscopy

Fully-Specified Name

Component: Polyp in which invasive carcinoma arose
Property: Type
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Microscopy.light

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Preferred Answer List LL4351-4

Answer	Code	Score	Answer ID
None identified			LA11904-2
Tubular adenoma			LA15387-6
Villous adenoma			LA15389-2
Tubular villous adenoma			LA15388-4
Traditional serrated adenoma			LA26492-1
Sessile serrated adenoma			LA27155-3
Hamartomatous polyp			LA27156-1
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πολύποδας στον οποίο εμφανίστηκε το διηθητικό καρκίνωμα:Type:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μικροσκόπηση.φωτός Synonyms: Type Πολύποδας στον οποίο εμφανίστηκε το διηθητικό καρκίνωμα
es-ES	Spanish (Spain)	Polipo en el que se origina el carcinoma:Tipo:Punto temporal:Cáncer colorectal:Nom:Microscopía de luz
es-MX	Spanish (Mexico)	Pólipo en el que surgió el carcinoma invasivo:Tipo:Punto temporal:Muestra de cáncer colorrectal:Nominal:Microscopía óptica
it-IT	Italian (Italy)	Polipo in cui è cresciuto il carcinoma invasivo:Tipo:Pt:Campione di carcinoma del colon-retto:Nom:Microscopia.ottica Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	其中发生浸润性癌的息肉:类型:时间点:结直肠癌标本:名义型:显微镜检查.光学 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样光学显微镜方法;光学显微镜方法.光学;光学显微镜检;光学显微镜检.光学;光学显微镜检查;光镜检查;光镜检查.光学;光镜法;显微镜检查.普通光学;普通光学显微镜检查;镜检;镜检.光学其中发生（出现、形成、形成）浸润性癌（浸润性癌症、浸润癌、侵袭性癌、侵袭性癌症）的息肉分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物型时刻;随机;随意;瞬间显微学;显微术;显微镜学;显微镜检术;显微镜检查;显微镜检查方法;显微镜检查法;显微镜检查类方法;显微镜检查类检验方法;显微镜法;镜检;镜检术;镜检法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81317-0 Additional pathological findings [Identifier] in Specimen

Term Description

Additional pathological findings identified in the specimen. For example, in gastric cancers, additional finding may include non-neoplastic pathologies such as gastritis, helicobacter infection, intestinal metaplasia, dysplasia, gastric polyps, Barrett's mucosa (for those specimens with esophagus) and others.

Fully-Specified Name

Component: Additional pathological findings
Property: Prid
Time: Pt
System: Specimen
Scale: Nom
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Observation

Example Answer List LL4009-8

Answer	Code	Score	Answer ID
Gastritis			LA26033-3
Helicobacter infection			LA26256-0
Intestinal metaplasia			LA26257-8
Gastric polyps			LA26258-6
Barrett's mucosa			LA26259-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πρόσθετα παθολογικά ευρήματα:Prid:Pt:Δείγμα:Nom: Synonyms: Prid Πρόσθετα παθολογικά ευρήματα
es-ES	Spanish (Spain)	Hallazgos patológicos adicionales:Presencia o identidad:Punto temporal:Especimen:Nom:
es-MX	Spanish (Mexico)	Hallazgos patológicos adicionales:Presencia o identidad:Punto temporal:Muestra:Nominal:
it-IT	Italian (Italy)	Ulteriori osservazioni patologiche:Prid:Pt:Campione:Nom: Synonyms: Patologia Presenza o Identità Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	additionele pathologische bevinding:identificator:moment:monster:nominaal:
ru-RU	Russian (Russian Federation)	Дополнительные патологические находки:ПрИд:ТчкВрм:Образец:Ном: Synonyms: Дополнительные патологоанатомические находки Номинальный;Именной порция;образец;материал для анализа Присутствие или Идентификация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Ek patolojik bolgular:MevcKimlik:Zmlı:Örnek:Snf: Synonyms: Spesmen
zh-CN	Chinese (China)	额外的病理学发现:存在与否或特征标识:时间点:标本:名义型: Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间样品样本试样附加的附加的病理学发现;额外的病理学所见;附加的病理学所见额外额外的

81691-8 DNA mismatch repair protein Mlh1 [Presence] in Cancer specimen by Immune stain

Part Descriptions

LP212189-7 DNA mismatch repair protein Mlh1
DNA mismatch repair proteins Mlh1, Msh2 and Msh6, and PMS2, an endonuclease, are all part of the post-replicative DNA mismatch repair system (MMR). Mutations in the MMR are associated with various hereditary cancer syndromes, including hereditary non-polyposis colorectal cancer (HNPCC) and mismatch repair cancer syndrome (MMRCS). HNPCC, also known as Lynch syndrome, is an autosomal dominant disease associated with familial predisposition to early-onset colorectal cancer (CRC) as well as cancer of other parts of the gastrointestinal tract, urological, and female reproductive tract. MMRCS is a rare autosomal recessive syndrome associated with various types of childhood cancer, including hematological malignancies, central nervous system tumors, CRC, intestinal polyps, embryonic tumors and rhabdomyosarcoma. [Uniprot: P40692] The pattern of immune staining for the different MMR proteins in biopsy or resection samples from colonic and other tumors associated with the above syndromes can provide information about the risk of Lynch syndrome and can help direct further genetic testing. PMID: 21297438 Source: Regenstrief LOINC , Uniprot: P40692

Fully-Specified Name

Component: DNA mismatch repair protein Mlh1
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Example Answer List LL3993-4

Answer	Code	Score	Answer ID
Intact nuclear expression			LA26197-6
Loss of nuclear expression			LA26198-4
Undetermined			LA14100-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πρωτεΐνη επιδιόρθωσης ασυμφωνίας DNA Mlh1:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: DNA PrThr Επιδιόρθωση ασυμφωνίας DNA Πρωτεΐνη Πρωτεΐνη επιδιόρθωσης ασυμφωνίας DNA Mlh1
es-ES	Spanish (Spain)	Proteína Mlh1 de repación de errores del ADN:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Proteína de reparación de desajustes de ADN Mlh1:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Mancata corrispondenza della riparazione del DNA proteina Mlh1:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	DNA 错配修复蛋白 Mlh1:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: DNA 错配修复（MMR）蛋白 Mlh1 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样

81692-6 DNA mismatch repair protein Msh2 [Presence] in Cancer specimen by Immune stain

Part Descriptions

LP212190-5 DNA mismatch repair protein Msh2
DNA mismatch repair proteins Mlh1, Msh2 and Msh6, and PMS2, an endonuclease, are all part of the post-replicative DNA mismatch repair system (MMR). Mutations in the MMR are associated with various hereditary cancer syndromes, including hereditary non-polyposis colorectal cancer (HNPCC) and mismatch repair cancer syndrome (MMRCS). HNPCC, also known as Lynch syndrome, is an autosomal dominant disease associated with familial predisposition to early-onset colorectal cancer (CRC) as well as cancer of other parts of the gastrointestinal tract, urological, and female reproductive tract. MMRCS is a rare autosomal recessive syndrome associated with various types of childhood cancer, including hematological malignancies, central nervous system tumors, CRC, intestinal polyps, embryonic tumors and rhabdomyosarcoma. [Uniprot: P40692] The pattern of immune staining for the different MMR proteins in biopsy or resection samples from colonic and other tumors associated with the above syndromes can provide information about the risk of Lynch syndrome and can help direct further genetic testing. PMID: 21297438 Source: Regenstrief LOINC , Uniprot: P40692

Fully-Specified Name

Component: DNA mismatch repair protein Msh2
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Example Answer List LL3993-4

Answer	Code	Score	Answer ID
Intact nuclear expression			LA26197-6
Loss of nuclear expression			LA26198-4
Undetermined			LA14100-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πρωτεΐνη επιδιόρθωσης ασυμφωνίας DNA Msh2:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: DNA PrThr Επιδιόρθωση ασυμφωνίας DNA Πρωτεΐνη Πρωτεΐνη επιδιόρθωσης ασυμφωνίας DNA Msh2
es-ES	Spanish (Spain)	Proteína Msh2 de repación de errores del ADN:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Proteína de reparación de desajustes de ADN Msh2:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Mancata corrispondenza della riparazione del DNA proteina Msh2:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	DNA 错配修复蛋白 Msh2:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: DNA 错配修复（MMR）蛋白 Msh2 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样

81693-4 DNA mismatch repair protein Msh6 [Presence] in Cancer specimen by Immune stain

Part Descriptions

LP212191-3 DNA mismatch repair protein Msh6
DNA mismatch repair proteins Mlh1, Msh2 and Msh6, and PMS2, an endonuclease, are all part of the post-replicative DNA mismatch repair system (MMR). Mutations in the MMR are associated with various hereditary cancer syndromes, including hereditary non-polyposis colorectal cancer (HNPCC) and mismatch repair cancer syndrome (MMRCS). HNPCC, also known as Lynch syndrome, is an autosomal dominant disease associated with familial predisposition to early-onset colorectal cancer (CRC) as well as cancer of other parts of the gastrointestinal tract, urological, and female reproductive tract. MMRCS is a rare autosomal recessive syndrome associated with various types of childhood cancer, including hematological malignancies, central nervous system tumors, CRC, intestinal polyps, embryonic tumors and rhabdomyosarcoma. [Uniprot: P40692] The pattern of immune staining for the different MMR proteins in biopsy or resection samples from colonic and other tumors associated with the above syndromes can provide information about the risk of Lynch syndrome and can help direct further genetic testing. PMID: 21297438 Source: Regenstrief LOINC , Uniprot: P40692

Fully-Specified Name

Component: DNA mismatch repair protein Msh6
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Example Answer List LL3993-4

Answer	Code	Score	Answer ID
Intact nuclear expression			LA26197-6
Loss of nuclear expression			LA26198-4
Undetermined			LA14100-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πρωτεΐνη επιδιόρθωσης ασυμφωνίας DNA Msh6:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: DNA PrThr Επιδιόρθωση ασυμφωνίας DNA Πρωτεΐνη Πρωτεΐνη επιδιόρθωσης ασυμφωνίας DNA Msh6
es-ES	Spanish (Spain)	Proteína Msh6 de repación de errores del ADN:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Proteína de reparación de desajustes de ADN Msh6:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Mancata corrispondenza della riparazione del DNA proteina Msh6:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	DNA 错配修复蛋白 Msh6:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: DNA 错配修复（MMR）蛋白 Msh6 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样

81694-2 Mismatch repair endonuclease PMS2 [Presence] in Cancer specimen by Immune stain

Part Descriptions

LP212192-1 Mismatch repair endonuclease PMS2
DNA mismatch repair proteins Mlh1, Msh2 and Msh6, and PMS2, an endonuclease, are all part of the post-replicative DNA mismatch repair system (MMR). Mutations in the MMR are associated with various hereditary cancer syndromes, including hereditary non-polyposis colorectal cancer (HNPCC) and mismatch repair cancer syndrome (MMRCS). HNPCC, also known as Lynch syndrome, is an autosomal dominant disease associated with familial predisposition to early-onset colorectal cancer (CRC) as well as cancer of other parts of the gastrointestinal tract, urological, and female reproductive tract. MMRCS is a rare autosomal recessive syndrome associated with various types of childhood cancer, including hematological malignancies, central nervous system tumors, CRC, intestinal polyps, embryonic tumors and rhabdomyosarcoma. [Uniprot: P40692] The pattern of immune staining for the different MMR proteins in biopsy or resection samples from colonic and other tumors associated with the above syndromes can provide information about the risk of Lynch syndrome and can help direct further genetic testing. PMID: 21297438 Source: Regenstrief LOINC , Uniprot: P40692

Fully-Specified Name

Component: Mismatch repair endonuclease PMS2
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Example Answer List LL3993-4

Answer	Code	Score	Answer ID
Intact nuclear expression			LA26197-6
Loss of nuclear expression			LA26198-4
Undetermined			LA14100-4

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ενδονουκλεάση επιδιόρθωσης ασυμφωνίας PMS2:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: PrThr Ενδονουκλεάση επιδιόρθωσης ασυμφωνίας PMS2
es-ES	Spanish (Spain)	Endonucleasa PMS2 de reparación de errores:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Reparación de desajustes endonucleasa PMS2:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Riparazione della mancata corrispondenza endonucleasi PMS2:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	错配修复内切核酸酶 PMS2:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样错配修复（MMR）内切核酸酶 PMS2

81711-4 Microsatellite instability marker panel - Cancer specimen

Part Descriptions

LP212222-6 Microsatellite instability marker panel
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker panel
Property: -
Time: Pt
System: Cancer specimen
Scale: -
Method

Basic Attributes

Class: PANEL.PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Order
Panel Type: Panel

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πίνακας δεικτών μικροδορυφορικής αστάθειας:-:Pt:Δείγμα καρκίνου:-: Synonyms: Μικροδορυφορική αστάθεια Πίνακας δεικτών μικροδορυφορικής αστάθειας
es-ES	Spanish (Spain)	Panel de marcadores de inestabilidad de microsatélites:Propiedades mixtas (sólo paneles):Punto temporal:Muestra de cancer:-:
es-MX	Spanish (Mexico)	Panel marcador de inestabilidad de microsatélites:-:Punto temporal:Espécimen de cáncer:-:
it-IT	Italian (Italy)	Marcatore di instabilità dei microsatelliti, panel:-:Pt:Campione tumore:-: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Panel Marcatore di instabilità dei microsatelliti Patologia Punto nel tempo (episodio) Set di prescrizione per patologia
zh-CN	Chinese (China)	微卫星不稳定性标记组套:-:时间点:癌标本:-: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样医嘱套餐医嘱套餐类医嘱套餐组医嘱组医嘱组.病理学;病理学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）医嘱组合医嘱组合类医嘱组套医嘱组套类医嘱组类受检物多重;多重型;多重标尺类型;多重精度类型套餐套餐医嘱套餐医嘱组套餐医嘱组类实验室医嘱套餐实验室医嘱套餐类实验室医嘱组实验室医嘱组合类实验室医嘱组套实验室医嘱组套类实验室套餐医嘱组实验室套餐医嘱组类实验室检验项目医嘱组合类实验室检验项目组合类微卫星不稳定性（MSI）标记（标记物、标志、标志物）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）时刻;随机;随意;瞬间样品样本检验医嘱组合类检验项目医嘱组合类检验项目组合类癌癌（癌症、癌变）标本（样本、样品、试样）组组合组合医嘱组合类组套试样

81696-7 Microsatellite instability markers assessed [#] in Cancer specimen

Fully-Specified Name

Component: Microsatellite instability markers assessed
Property: Num
Time: Pt
System: Cancer specimen
Scale: Qn
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας:Αρ.:Pt:Δείγμα καρκίνου:Qn: Synonyms: Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας Αρ. Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcadores evaluados de inestabilidad de microsatélites:Número (recuento):Punto temporal:Muestra de cancer:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Marcadores de inestabilidad de microsatélites evaluados:Número (recuento):Punto temporal:Espécimen de cáncer:Cuantitativo:
it-IT	Italian (Italy)	Marcatori di instabilità dei microsatelliti valutati:Num:Pt:Campione tumore:Qn: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	所评估的微卫星不稳定性标记:数量(计数):时间点:癌标本:定量型: Synonyms: MSI 个数;数量;数量或计数（非负整数）;计数供检查用的材料;待检物;待试验物;样品;样本;试料;试样受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺所评估的（已评估的、所评价的、已评价的）微卫星不稳定性（MSI）标记（标记物、标志、标志物）时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Example Units

Unit	Source
{#}	Example UCUM Units

81697-5 Microsatellite instability marker BAT25 in Cancer specimen Qualitative

Part Descriptions

LP212210-1 Microsatellite instability marker BAT25
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker BAT25
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας BAT25:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας BAT25 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador BAT25 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites BAT25:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore BAT25 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 BAT25:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） BAT25 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81698-3 Microsatellite instability marker BAT26 in Cancer specimen Qualitative

Part Descriptions

LP212211-9 Microsatellite instability marker BAT26
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker BAT26
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας BAT26:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας BAT26 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador BAT26 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites BAT26:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore BAT26 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 BAT26:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） BAT26 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81699-1 Microsatellite instability marker NR21 in Cancer specimen Qualitative

Part Descriptions

LP212212-7 Microsatellite instability marker NR21
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker NR21
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας NR21:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας NR21 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador NR21 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites NR21:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore NR21 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 NR21:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） NR21 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81700-7 Microsatellite instability marker NR24 in Cancer specimen Qualitative

Part Descriptions

LP212213-5 Microsatellite instability marker NR24
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker NR24
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας NR24:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας NR24 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador NR24 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites NR24:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore NR24 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 NR24:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） NR24 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81701-5 Microsatellite instability marker MONO27 in Cancer specimen Qualitative

Part Descriptions

LP212214-3 Microsatellite instability marker MONO27
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker MONO27
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας MONO27:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας MONO27 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	MarcadorMONO27 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites MONO27:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	MarcatoreMONO27 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 MONO27:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） MONO27 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81702-3 Microsatellite instability marker D2S123 in Cancer specimen Qualitative

Part Descriptions

LP212215-0 Microsatellite instability marker D2S123
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker D2S123
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας D2S123:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας D2S123 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador D2S123 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites D2S123:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore D2S123 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 D2S123:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） D2S123 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81703-1 Microsatellite instability marker D5S346 in Cancer specimen Qualitative

Part Descriptions

LP212216-8 Microsatellite instability marker D5S346
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker D5S346
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας D5S346:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας D5S346 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador D5S346 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites D5S346:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore D5S346 di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 D5S346:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） D5S346 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81704-9 Microsatellite instability marker D17S250 in Cancer specimen Qualitative

Part Descriptions

LP212217-6 Microsatellite instability marker D17S250
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability marker D17S250
Property: Find
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL1057-0

Answer	Code	Score	Answer ID
Stable			LA14122-8
Unstable			LA14123-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Δείκτης μικροδορυφορικής αστάθειας D17S250:Εύρεση:Pt:Δείγμα καρκίνου:Ord: Synonyms: Δείκτης μικροδορυφορικής αστάθειας D17S250 Εύρεση Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Marcador 17S250 de inestabilidad de microsatélites:Hallazgo:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Marcador de inestabilidad de microsatélites D17S250:Hallazgo:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Marcatore D17S250di instabilità dei microsatelliti:Osservazione:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性标记 D17S250:发现:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论受检物微卫星不稳定性（MSI）标记（标记物、标志、标志物） D17S250 时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81709-8 Microsatellite markers exhibiting instability [#] in Cancer specimen

Part Descriptions

LP212220-0 Microsatellite markers exhibiting instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite markers exhibiting instability
Property: Num
Time: Pt
System: Cancer specimen
Scale: Qn
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια:Αρ.:Pt:Δείγμα καρκίνου:Qn: Synonyms: Αρ. Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια
es-ES	Spanish (Spain)	Marcadores de inestabilidad de microsatelites:Número (recuento):Punto temporal:Muestra de cancer:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Marcadores de microsatélites que presentan inestabilidad:Número (recuento):Punto temporal:Espécimen de cáncer:Cuantitativo:
it-IT	Italian (Italy)	Marcatori di microsatelliti che dimostrano instabilità:Num:Pt:Campione tumore:Qn: Synonyms: Campione di tumore Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	表现不稳定性的微卫星标记:数量(计数):时间点:癌标本:定量型: Synonyms: 个数;数量;数量或计数（非负整数）;计数供检查用的材料;待检物;待试验物;样品;样本;试料;试样受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）表现（展现、体现、显现、显示、存在）不稳定性的微卫星标记试样

Example Units

Unit	Source
{#}	Example UCUM Units

81708-0 Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen

Part Descriptions

LP212220-0 Microsatellite markers exhibiting instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

LP212221-8 Microsatellite instability markers assessed
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite markers exhibiting instability/Microsatellite instability markers assessed
Property: NFr
Time: Pt
System: Cancer specimen
Scale: Qn
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια/Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας:NFr:Pt:Δείγμα καρκίνου:Qn: Synonyms: NFr Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας Μικροδορυφορική αστάθεια Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια
es-ES	Spanish (Spain)	Marcadores de inestabilidad de microsatelites/Marcadores de inestabilidad de microsatélites evaluados:Fracción numérica:Punto temporal:Muestra de cancer:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Marcadores de microsatélites que presentan inestabilidad / Marcadores de inestabilidad de microsatélites evaluados:Fracción numérica:Punto temporal:Espécimen de cáncer:Cuantitativo:
it-IT	Italian (Italy)	Marcatori di microsatelliti che dimostrano instabilità/Marcatori di instabilità dei microsatelliti valutati:NFr:Pt:Campione tumore:Qn: Synonyms: Campione di tumore Frazione numerica Instabilità dei microsatelliti Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	表现不稳定性的微卫星标记/所评估的微卫星不稳定性标记:计数型分数:时间点:癌标本:定量型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺所评估的（已评估的、所评价的、已评价的）微卫星不稳定性（MSI）标记（标记物、标志、标志物）数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）表现（展现、体现、显现、显示、存在）不稳定性的微卫星标记试样

Example Units

Unit	Source
%	Example UCUM Units

81695-9 Microsatellite instability [Interpretation] in Cancer specimen Qualitative

Part Descriptions

LP36464-3 Microsatellite instability
The appearance of abnormally long or short microsatellites in an individual's DNA is referred to as microsatellite instability. Microsatellite instability (MSI) is a condition manifested by damaged DNA due to defects in the normal DNA repair process. Sections of DNA called microsatellites, which consist of a sequence of repeating units of 1-6 base pairs in length, become unstable and can shorten or lengthen. Microsatellites are also known as simple sequence repeats (SSRs). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

LP36464-3 Microsatellite instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component: Microsatellite instability
Property: Imp
Time: Pt
System: Cancer specimen
Scale: Ord
Method

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL3994-2

Answer	Code	Score	Answer ID
Stable			LA14122-8
MSI-L			LA26202-4
MSI-H			LA26203-2
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
81711-4	Microsatellite instability marker panel - Cancer specimen

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μικροδορυφορική αστάθεια:Imp:Pt:Δείγμα καρκίνου:Ord: Synonyms: Imp Μικροδορυφορική αστάθεια
es-ES	Spanish (Spain)	Inestabilidad microsatelite:Impresión/interpretación del estudio:Punto temporal:Muestra de cancer:Ord:
es-MX	Spanish (Mexico)	Inestabilidad de microsatélites:Impresión / interpretación del estudio:Punto temporal:Espécimen de cáncer:Ordinal:
it-IT	Italian (Italy)	Microsatelliti, instabilità:Imp:Pt:Campione tumore:Ord: Synonyms: Campione di tumore Impressione/interpretazione di studio Instabilità dei microsatelliti Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	微卫星不稳定性:印象:时间点:癌标本:序数型: Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释受检物时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

58416-9 MLH1 gene methylation [Presence] in Blood or Tissue by Molecular genetics method

Part Descriptions

LP99240-1 MLH1 gene methylation
MLH1 gene methylation has been associated with many kinds of cancers with microsatellite instability Source: Regenstrief LOINC

LP124510-1 gene methylation
DNA methylation is essential during embryonic development, and patterns of DNA methylation are generally transmitted to daughter cells with a high fidelity. In cancer, aberrant DNA methylation patterns are found in two distinct forms: hypermethylation and hypomethylation. Hypermethylation is one of the major epigenetic modifications that repress transcription via the promoter region of tumor suppressor genes. Hypermethylation typically occurs at CpG islands in the promoter region and is associated with gene inactivation. Hypomethylation, linked to chromosomal instability and loss of imprinting, arises earlier and occurs throughout the progression of cancer.

More specifically, methylated DNA can bind to methyl-CpG-binding domain proteins (MBDs), which recruit additional proteins such as histone deacetylases and other chromatin remodeling proteins that modify histones to form compact, inactive chromatin, termed silent chromatin. Loss of methyl-CpG-binding protein 2 (MeCP2) has been implicated in Rett syndrome; and methyl-CpG-binding domain protein 2 (MBD2) mediates the transcriptional silencing of hypermethylated genes in cancer. Research has suggested that long-term memory storage in humans may be regulated by DNA methylation. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

Fully-Specified Name

Component: MLH1 gene methylation
Property: PrThr
Time: Pt
System: Bld/Tiss
Scale: Ord
Method: Molgen

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.30
Last Updated: Version 2.73 (MIN)
Change Reason: Release 2.72: PROPERTY: Updated Property from Arb to align with similar terms; SYSTEM: Updated System from Tiss as this test can be done using blood or tissue specimens;
Order vs. Observation: Both
Common Test Rank Get Info: 15582

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μεθυλίωση γονιδίου MLH1:PrThr:Pt:Αίμα/Ιστός:Ord:Μοριακή γενετική Synonyms: PrThr Γονίδιο Γονίδιο MLH1 Μεθυλίωση γονιδίου MLH1
es-ES	Spanish (Spain)	Metilación del gen MLH1:PrThr:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX	Spanish (Mexico)	Metilación del gen MLH1:Arbitrario:Punto temporal:Tejido y frotis:Ordinal:Genética molecular
fr-FR	French (France)	MLH1 gène méthylation:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	MLH1, metilazione gene:PrThr:Pt:Sangue/Tess:Ord:Molgen Synonyms: Gene MLH1 Genetica molecolare Metilazione del gene MLH1 Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL	Dutch (Netherlands)	MLH1 genmethylatie:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek Synonyms: MLH1 gen molgen
pt-BR	Portuguese (Brazil)	MLH1 gene metilação:#N/A:Pt:Tecido:Ord:Genética molecular Synonyms: MutL homolog 1, colon cancer, nonpolyposis type 2; COCA2; FCC2; HNPCC; HNPCC2; MGC5172; hMLH1; Arbitrary; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Molecular pathology
ru-RU	Russian (Russian Federation)	MLH1 ген метилирование:PrThr:ТчкВрм:Кр/Тк:Пор:МолГен Synonyms: Кровь Кровь или Ткань Порядковый Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	MLH1 geni metilation:MevcEşik:Zmlı:Kan/Dk:Srl:Molgen Synonyms: Mevcut
zh-CN	Chinese (China)	MLH1 基因甲基化:存在情况或阈值:时间点:全血/组织:序数型:分子遗传学类实验室方法 Synonyms: COCA2;FCC2;hMLH1;HNPCC;HNPCC2;MGC5172;MutL 同源基因 1, 结肠癌, 非多发性息肉 2 型;MutL 同源基因 1, 结肠癌, 非息肉病 2 型依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型全血或组织;血液/组织;血液或组织分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片血;血液遗传基因;遗传因子;吉恩;生物基因

83059-6 KRAS gene [VCF] in Cancer specimen by Sequencing

Term Description

This term is used to report the variant call file (VCF) associated with the KRAS gene sequence in a cancer specimen.

Part Descriptions

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP19732-4 KRAS gene
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: KRAS gene
Property: VCF
Time: Pt
System: Cancer specimen
Scale: Doc
Method: Sequencing

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.65 (MIN)
Change Reason: Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο KRAS:VCF:Pt:Δείγμα καρκίνου:Doc:Αλληλούχιση Synonyms: VCF Γονίδιο Γονίδιο KRAS
es-ES	Spanish (Spain)	Gen KRAS:VCF:Punto temporal:Muestra de cancer:Doc:Secuenciación
es-MX	Spanish (Mexico)	Gen KRAS:Archivo de llamada variante:Punto temporal:Espécimen de cáncer:Documento:Secuenciación
fr-FR	French (France)	KRAS gène:Liste de variant:Ponctuel:Tissu cancereux:Document:Séquençage
it-IT	Italian (Italy)	KRAS, gene:VCF:Pt:Campione tumore:Doc:Sequenziamento Synonyms: Campione di tumore Gene KRAS Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file
zh-CN	Chinese (China)	KRAS2 基因:VCF:时间点:癌标本:文档型:序列测定 Synonyms: Kirsten 大鼠肉瘤病毒 2;RASK1;RASK2;V-KI-RAS1 假基因;V-KI-RAS1 拟基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性致癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒癌基因同源基因;癌基因 KRAS1;癌基因 KRAS2;致癌基因 KRAS1;致癌基因 KRAS2 Variant call file;变异（遗传性变异、基因变异、遗传变异）检出（call，识别，调用）文件;VCF文件临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学;分子病理学试验受检物序列分析;测序时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样遗传基因;遗传因子;吉恩;生物基因

85509-8 KRAS gene mutations found [Identifier] in Colorectal cancer specimen by Molecular genetics method Nominal

Part Descriptions

LP19732-4 KRAS gene
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: KRAS gene targeted mutation analysis
Property: Prid
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Molgen

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο KRAS στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μοριακή γενετική Synonyms: Prid Γονίδιο Γονίδιο KRAS
es-ES	Spanish (Spain)	Gen KRAS Analisis de mutaciones:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen KRAS:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Genética molecular
fr-FR	French (France)	KRAS gène mutation cible trouvée:Identification:Ponctuel:Tissu cancer colorectal:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	KRAS, gene analisi di mutazione mirata:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Molgen Synonyms: Campione di tumore Gene KRAS Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio)
zh-CN	Chinese (China)	KRAS2 基因突变分析:存在与否或特征标识:时间点:结直肠癌标本:名义型:分子遗传学类实验室方法 Synonyms: Kirsten 大鼠肉瘤病毒 2;RASK1;RASK2;V-KI-RAS1 假基因;V-KI-RAS1 拟基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性致癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒癌基因同源基因;癌基因 KRAS1;癌基因 KRAS2;致癌基因 KRAS1;致癌基因 KRAS2 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样遗传基因;遗传因子;吉恩;生物基因

83060-4 NRAS gene [VCF] in Cancer specimen by Sequencing

Term Description

This term is used to report the variant call file (VCF) associated with the NRAS gene sequence in a cancer specimen.

Part Descriptions

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP19749-8 NRAS gene
The NRAS gene (neuroblastoma RAS viral (v-ras) oncogene homolog) [HGNC Gene ID:7989] is located on chromosome 1p13.2. This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] [NCBI Gene ID:4893] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: NRAS gene
Property: VCF
Time: Pt
System: Cancer specimen
Scale: Doc
Method: Sequencing

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.65 (MIN)
Change Reason: Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο NRAS:VCF:Pt:Δείγμα καρκίνου:Doc:Αλληλούχιση Synonyms: VCF Γονίδιο Γονίδιο NRAS
es-ES	Spanish (Spain)	Gen NRAS:VCF:Punto temporal:Muestra de cancer:Doc:Secuenciación
es-MX	Spanish (Mexico)	Gen NRAS:Archivo de llamada variante:Punto temporal:Espécimen de cáncer:Documento:Secuenciación
fr-FR	French (France)	NRAS gène:Liste de variant:Ponctuel:Tissu cancereux:Document:Séquençage
it-IT	Italian (Italy)	NRAS, gene:VCF:Pt:Campione tumore:Doc:Sequenziamento Synonyms: Campione di tumore Gene NRAS Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file
zh-CN	Chinese (China)	NRAS 基因:VCF:时间点:癌标本:文档型:序列测定 Synonyms: Variant call file;变异（遗传性变异、基因变异、遗传变异）检出（call，识别，调用）文件;VCF文件 v-ras 成神经细胞瘤 RAS 病毒癌基因同源基因;v-ras 神经母细胞瘤 RAS 病毒癌基因同源基因;癌基因 NRAS;致癌基因 NRAS 临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学;分子病理学试验受检物序列分析;测序时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样遗传基因;遗传因子;吉恩;生物基因

85510-6 NRAS gene mutations found [Identifier] in Colorectal cancer specimen by Molecular genetics method Nominal

Part Descriptions

LP19749-8 NRAS gene
The NRAS gene (neuroblastoma RAS viral (v-ras) oncogene homolog) [HGNC Gene ID:7989] is located on chromosome 1p13.2. This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] [NCBI Gene ID:4893] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: NRAS gene targeted mutation analysis
Property: Prid
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Molgen

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο NRAS στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μοριακή γενετική Synonyms: Prid Γονίδιο Γονίδιο NRAS
es-ES	Spanish (Spain)	Gen NRAS Analisis de mutaciones:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen NRAS:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Genética molecular
fr-FR	French (France)	NRAS gène mutation cible trouvée:Identification:Ponctuel:Tissu cancer colorectal:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	NRAS, gene analisi di mutazione mirata:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Molgen Synonyms: Campione di tumore Gene NRAS Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio)
zh-CN	Chinese (China)	NRAS 基因突变分析:存在与否或特征标识:时间点:结直肠癌标本:名义型:分子遗传学类实验室方法 Synonyms: v-ras 成神经细胞瘤 RAS 病毒癌基因同源基因;v-ras 神经母细胞瘤 RAS 病毒癌基因同源基因;癌基因 NRAS;致癌基因 NRAS 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样遗传基因;遗传因子;吉恩;生物基因

81705-6 BRAF protein [Presence] in Cancer specimen by Immune stain

Part Descriptions

LP212224-2 Serine-threonine protein kinase B-raf
The BRAF gene (B-Raf proto-oncogene, serine/threonine kinase) [HGNC Gene ID:1097] is located on chromosome 7q34. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:673] Loss of the BRAF gene can be determined by various techniques, and loss of the protein, which is an indicator of gene mutation or deletion, can be detected by immunohistochemistry techniques. Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: Serine-threonine protein kinase B-raf
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because BRAF protein immune staining is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL2038-9

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: B PrThr Θρεονίνη Πρωτεΐνη Πρωτεϊνική κινάση Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf Σερίνη
es-ES	Spanish (Spain)	B-raf serina-treonina protein quinasa:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Serina-treonina proteína quinasa B-raf:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Serina-treonina proteina chinasi B-raf:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia PKA Presenza o Soglia Proteina BRAF Punto nel tempo (episodio)
zh-CN	Chinese (China)	丝氨酸-苏氨酸蛋白激酶 B-raf:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: B 型 Beta-羟丁氨酸;Thr;β-羟丁氨酸;羟基丁氨酸 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 Ser STK B-raf 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

85299-6 BRAF V600E mutant protein [Presence] in Cancer specimen by Immune stain

Fully-Specified Name

Component: Serine-threonine protein kinase B-raf V600E
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL744-4

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf V600E:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: B PrThr Θρεονίνη Πρωτεΐνη Πρωτεϊνική κινάση Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf V600E Σερίνη
es-ES	Spanish (Spain)	proteína serina/treonina quinasa B-Raf mutación V600E:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Serina-treonina proteína quinasa B-raf V600E:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Serina-treonina proteina chinasi B-raf V600E:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia PKA Presenza o Soglia Proteina BRAF Proteina mutante BRAF V600E Punto nel tempo (episodio)
zh-CN	Chinese (China)	丝氨酸-苏氨酸蛋白激酶 B-raf V600E:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: B 型 Beta-羟丁氨酸;Thr;β-羟丁氨酸;羟基丁氨酸 BRAF V600E;STK B-raf V600E PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 Ser STK B-raf 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样

83061-2 BRAF gene [VCF] in Cancer specimen by Sequencing

Term Description

This term is used to report the variant call file (VCF) associated with the BRAF gene sequence in a cancer specimen.

Part Descriptions

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP71409-4 BRAF gene
The BRAF gene (B-Raf proto-oncogene, serine/threonine kinase) [HGNC Gene ID:1097] is located on chromosome 7q34. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:673] Loss of the BRAF gene can be determined by various techniques, and loss of the protein, which is an indicator of gene mutation or deletion, can be detected by immunohistochemistry techniques. Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: BRAF gene
Property: VCF
Time: Pt
System: Cancer specimen
Scale: Doc
Method: Sequencing

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.65 (MIN)
Change Reason: Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο BRAF:VCF:Pt:Δείγμα καρκίνου:Doc:Αλληλούχιση Synonyms: VCF Γονίδιο Γονίδιο BRAF
es-ES	Spanish (Spain)	Gen BRAF:VCF:Punto temporal:Muestra de cancer:Doc:Secuenciación
es-MX	Spanish (Mexico)	Gen BRAF:Archivo de llamada variante:Punto temporal:Espécimen de cáncer:Documento:Secuenciación
fr-FR	French (France)	BRAF gène:Liste de variant:Ponctuel:Tissu cancereux:Document:Séquençage
it-IT	Italian (Italy)	BRAF, gene:VCF:Pt:Campione tumore:Doc:Sequenziamento Synonyms: Campione di tumore Gene BRAF Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file
zh-CN	Chinese (China)	BRAF 基因:VCF:时间点:癌标本:文档型:序列测定 Synonyms: B-Raf;原癌基因 B-Raf;proto-oncogene B-Raf;v-Raf murine sarcoma viral oncogene homolog B1;v-Raf 鼠科肉瘤病毒癌基因同源物 B1;v-Raf 小鼠肉瘤病毒癌基因同源物 B1;serine/threonine-protein kinase B-Raf;丝氨酸/苏氨酸蛋白激酶 B-Raf;丝氨酸-苏氨酸蛋白激酶 B-Raf;甲状腺癌;消化道肿瘤;皮肤黑色素瘤 Variant call file;变异（遗传性变异、基因变异、遗传变异）检出（call，识别，调用）文件;VCF文件临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学;分子病理学试验受检物序列分析;测序时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样遗传基因;遗传因子;吉恩;生物基因

85511-4 BRAF gene mutations found [Identifier] in Colorectal cancer specimen by Molecular genetics method Nominal

Part Descriptions

LP71409-4 BRAF gene
The BRAF gene (B-Raf proto-oncogene, serine/threonine kinase) [HGNC Gene ID:1097] is located on chromosome 7q34. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:673] Loss of the BRAF gene can be determined by various techniques, and loss of the protein, which is an indicator of gene mutation or deletion, can be detected by immunohistochemistry techniques. Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: BRAF gene targeted mutation analysis
Property: Prid
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Molgen

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο BRAF στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μοριακή γενετική Synonyms: Prid Γονίδιο Γονίδιο BRAF
es-ES	Spanish (Spain)	Gen BRAF Analisis de mutaciones:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen BRAF:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Genética molecular
fr-FR	French (France)	BRAF gène mutation cible trouvée:Identification:Ponctuel:Tissu cancer colorectal:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	BRAF, gene analisi di mutazione mirata:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Molgen Synonyms: Campione di tumore Gene BRAF Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio)
zh-CN	Chinese (China)	BRAF 基因突变分析:存在与否或特征标识:时间点:结直肠癌标本:名义型:分子遗传学类实验室方法 Synonyms: B-Raf;原癌基因 B-Raf;proto-oncogene B-Raf;v-Raf murine sarcoma viral oncogene homolog B1;v-Raf 鼠科肉瘤病毒癌基因同源物 B1;v-Raf 小鼠肉瘤病毒癌基因同源物 B1;serine/threonine-protein kinase B-Raf;丝氨酸/苏氨酸蛋白激酶 B-Raf;丝氨酸-苏氨酸蛋白激酶 B-Raf;甲状腺癌;消化道肿瘤;皮肤黑色素瘤供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样遗传基因;遗传因子;吉恩;生物基因

83062-0 PIK3CA gene [VCF] in Cancer specimen by Sequencing

Term Description

This term is used to report the variant call file (VCF) associated with the PIK3CA gene sequence in a cancer specimen.

Part Descriptions

LP101031-5 PIK3CA gene
The PIK3CA gene (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) [HGNC Gene ID:8975] is located on chromosome 3q26.3. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] [NCBI Gene ID:5290] Source: National Center for Biotechnology Information (NCBI) Gene

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component: PIK3CA gene
Property: VCF
Time: Pt
System: Cancer specimen
Scale: Doc
Method: Sequencing

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.65 (MIN)
Change Reason: Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο PIK3CA:VCF:Pt:Δείγμα καρκίνου:Doc:Αλληλούχιση Synonyms: VCF Γονίδιο Γονίδιο PIK3CA
es-ES	Spanish (Spain)	Gen PIK3CA:VCF:Punto temporal:Muestra de cancer:Doc:Secuenciación
es-MX	Spanish (Mexico)	Gen PIK3CA:Archivo de llamada variante:Punto temporal:Espécimen de cáncer:Documento:Secuenciación
fr-FR	French (France)	PIK3CA gène:Liste de variant:Ponctuel:Tissu cancereux:Document:Séquençage
it-IT	Italian (Italy)	PIK3CA, gene:VCF:Pt:Campione tumore:Doc:Sequenziamento Synonyms: Campione di tumore Gene PIK3CA Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file
zh-CN	Chinese (China)	PIK3CA 基因:VCF:时间点:癌标本:文档型:序列测定 Synonyms: MGC142161;MGC142163;p110-alpha;p110-α;PI3K Variant call file;变异（遗传性变异、基因变异、遗传变异）检出（call，识别，调用）文件;VCF文件临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学;分子病理学试验受检物序列分析;测序时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样遗传基因;遗传因子;吉恩;生物基因

85507-2 PIK3CA gene mutations found [Identifier] in Colorectal cancer specimen by Molecular genetics method Nominal

Part Descriptions

LP101031-5 PIK3CA gene
The PIK3CA gene (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) [HGNC Gene ID:8975] is located on chromosome 3q26.3. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] [NCBI Gene ID:5290] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: PIK3CA gene targeted mutation analysis
Property: Prid
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Molgen

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο PIK3CA στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μοριακή γενετική Synonyms: Prid Γονίδιο Γονίδιο PIK3CA
es-ES	Spanish (Spain)	Gen PIK3CA Analisis de mutaciones:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen PIK3CA:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Genética molecular
fr-FR	French (France)	PIK3CA gène mutation cible trouvée:Identification:Ponctuel:Tissu cancer colorectal:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	PIK3CA, gene analisi di mutazione mirata:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Molgen Synonyms: Campione di tumore Gene PIK3CA Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio)
zh-CN	Chinese (China)	PIK3CA 基因突变分析:存在与否或特征标识:时间点:结直肠癌标本:名义型:分子遗传学类实验室方法 Synonyms: MGC142161;MGC142163;p110-alpha;p110-α;PI3K 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样遗传基因;遗传因子;吉恩;生物基因

81706-4 Phosphatase and tensin homolog (PTEN) protein [Presence] in Cancer specimen by Immune stain

Part Descriptions

LP212218-4 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques. Source: Regenstrief LOINC , UniProt: P60484

Fully-Specified Name

Component: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: Immune stain

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because PTEN protein immune staining is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL2038-9

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	3-φωσφατάση της 3,4,5,-τριφωσφορικής φωσφατιδυλινοσιτόλης και διπλής ειδικότητας πρωτεϊνική φωσφατάση PTEN:PrThr:Pt:Δείγμα καρκίνου:Ord:Ανοσολογική χρώση Synonyms: 3-φωσφατάση της 3,4,5,-τριφωσφορικής φωσφατιδυλινοσιτόλης και διπλής ειδικότητας πρωτεϊνική φωσφατάση PTEN PrThr Πρωτεΐνη Φωσφατιδυλινοσιτόλη
es-ES	Spanish (Spain)	Fosfatidilinositol 3,4,5-trifosfato 3-fosfatasa y especificidad dual de proteinfosfatasa PTEN:PrThr:Punto temporal:Muestra de cancer:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Fosfatidilinositol 3,4,5-trifosfato 3-fosfatasa y proteína fosfatasa de especificidad dual PTEN:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Mancha inmune
it-IT	Italian (Italy)	Fosfatidilinositolo 3,4,5- trifosfato 3-fosfato e proteina PTEN fosfatasi a doppia specificità:PrThr:Pt:Campione tumore:Ord:Colorazione immunologica Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	磷脂酰肌醇 3,4,5-三磷酸 3-磷酸酯酶与双特异性蛋白磷酸酯酶 PTEN:存在情况或阈值:时间点:癌标本:序数型:免疫染色法 Synonyms: Ⅲ III PI;磷脂酰环己六醇;磷脂酰肌;磷脂酰肌醇（Phosphatidylinositol，PI） PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质三供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法叁受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法磷脂酰肌醇（PI、磷脂酰环己六醇、磷脂酰肌、磷脂酰肌醇） 3,4,5-三磷酸 3-磷酸酯酶（磷酸酶）与双特异性（双重特异性）蛋白磷酸酯酶（磷酸酶） PTEN 磷酸单酯酶磷酸酶试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

81710-6 PTEN gene [Presence] in Cancer specimen by FISH

Part Descriptions

LP61787-5 PTEN gene
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques. Source: Regenstrief LOINC , UniProt: P60484

LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , FISH

Fully-Specified Name

Component: PTEN gene
Property: PrThr
Time: Pt
System: Cancer specimen
Scale: Ord
Method: FISH

Basic Attributes

Class: MOLPATH.MISC
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MAJ)
Change Reason: Updated System from "Tiss" to "Cancer.XXX" because PTEN gene testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Observation

Example Answer List LL2038-9

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο PTEN:PrThr:Pt:Δείγμα καρκίνου:Ord:Φθορίζουσα υβριδοποίηση in situ Synonyms: PrThr Γονίδιο Γονίδιο PTEN
es-ES	Spanish (Spain)	Gen PTEN:PrThr:Punto temporal:Muestra de cancer:Ord:Hibridación in situ fluoresente (FISH)
es-MX	Spanish (Mexico)	Gen PTEN:Presencia o umbral:Punto temporal:Espécimen de cáncer:Ordinal:Hibridación fluorescente in situ (FISH)
fr-FR	French (France)	PTEN gène:Présence/Seuil:Ponctuel:Tissu cancereux:Qualitatif:FISH
it-IT	Italian (Italy)	PTEN, gene:PrThr:Pt:Campione tumore:Ord:FISH Synonyms: Campione di tumore Gene PTEN Ibridazione in situ fluorescente (FISH) Miscellanea Miscellanea geni Neoplasia maligna Patologia molecolare Presenza o Soglia Punto nel tempo (episodio)
zh-CN	Chinese (China)	PTEN 基因:存在情况或阈值:时间点:癌标本:序数型:FISH Synonyms: Bannayan-Zonana 综合征（Bannayan-Zonana syndrome，BZS）;BZS;Human mutated in multiple advanced cancers protein (MMAC1) mRNA, complete cds;MGC11227;MHAM;MMAC1;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;PTEN1;TEP1;人类突变于多种进行性癌蛋白 (MMAC1) Fluorescent in situ hybridization;荧光原位杂交供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子病理学.杂项;分子病理学试验.杂项;分子病理学试验类.其他分子病理学;分子病理学试验受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间杂项;杂项类;杂项试验样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样遗传基因;遗传因子;吉恩;生物基因

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

83063-8 PTEN gene [VCF] in Cancer specimen by Sequencing

Term Description

This term is used to report the variant call file (VCF) associated with the PTEN gene sequence in a cancer specimen.

Part Descriptions

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP61787-5 PTEN gene
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques. Source: Regenstrief LOINC , UniProt: P60484

Fully-Specified Name

Component: PTEN gene
Property: VCF
Time: Pt
System: Cancer specimen
Scale: Doc
Method: Sequencing

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.65 (MIN)
Change Reason: Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο PTEN:VCF:Pt:Δείγμα καρκίνου:Doc:Αλληλούχιση Synonyms: VCF Γονίδιο Γονίδιο PTEN
es-ES	Spanish (Spain)	Gen PTEN:VCF:Punto temporal:Muestra de cancer:Doc:Secuenciación
es-MX	Spanish (Mexico)	Gen PTEN:Archivo de llamada variante:Punto temporal:Espécimen de cáncer:Documento:Secuenciación
fr-FR	French (France)	PTEN gène:Liste de variant:Ponctuel:Tissu cancereux:Document:Séquençage
it-IT	Italian (Italy)	PTEN, gene:VCF:Pt:Campione tumore:Doc:Sequenziamento Synonyms: Campione di tumore Gene PTEN Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file
zh-CN	Chinese (China)	PTEN 基因:VCF:时间点:癌标本:文档型:序列测定 Synonyms: Bannayan-Zonana 综合征（Bannayan-Zonana syndrome，BZS）;BZS;Human mutated in multiple advanced cancers protein (MMAC1) mRNA, complete cds;MGC11227;MHAM;MMAC1;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;PTEN1;TEP1;人类突变于多种进行性癌蛋白 (MMAC1) Variant call file;变异（遗传性变异、基因变异、遗传变异）检出（call，识别，调用）文件;VCF文件临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学;分子病理学试验受检物序列分析;测序时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样遗传基因;遗传因子;吉恩;生物基因

85506-4 PTEN gene mutations found [Identifier] in Colorectal cancer specimen by Molecular genetics method Nominal

Part Descriptions

LP61787-5 PTEN gene
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques. Source: Regenstrief LOINC , UniProt: P60484

Fully-Specified Name

Component: PTEN gene targeted mutation analysis
Property: Prid
Time: Pt
System: Colorectal cancer specimen
Scale: Nom
Method: Molgen

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο PTEN στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Δείγμα καρκίνου του παχέος εντέρου:Nom:Μοριακή γενετική Synonyms: Prid Γονίδιο Γονίδιο PTEN
es-ES	Spanish (Spain)	Gen PTEN Analisis de mutaciones:Presencia o identidad:Punto temporal:Cáncer colorectal:Nom:Genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen PTEN:Presencia o identidad:Punto temporal:Muestra de cáncer colorrectal:Nominal:Genética molecular
fr-FR	French (France)	PTEN gène mutation cible trouvée:Identification:Ponctuel:Tissu cancer colorectal:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	PTEN, gene analisi di mutazione mirata:Prid:Pt:Campione di carcinoma del colon-retto:Nom:Molgen Synonyms: Campione di tumore Gene PTEN Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio)
zh-CN	Chinese (China)	PTEN 基因突变分析:存在与否或特征标识:时间点:结直肠癌标本:名义型:分子遗传学类实验室方法 Synonyms: Bannayan-Zonana 综合征（Bannayan-Zonana syndrome，BZS）;BZS;Human mutated in multiple advanced cancers protein (MMAC1) mRNA, complete cds;MGC11227;MHAM;MMAC1;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;PTEN1;TEP1;人类突变于多种进行性癌蛋白 (MMAC1) 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本试样遗传基因;遗传因子;吉恩;生物基因

81707-2 Dissection technique [Type] in Tissue

Part Descriptions

LP212219-2 Dissection technique
Various dissection methods for use with frozen or paraffin-embedded tissue sections exist that allow investigators to select the cells or areas of interest for further examination and to separate them cleanly from the background tissue. These methods include laser capture, microdissection under microscopy, manual dissection, and coring from block. Source: Regenstrief LOINC

Fully-Specified Name

Component: Dissection technique
Property: Type
Time: Pt
System: Tiss
Scale: Nom
Method: *

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.56 (MIN)
Order vs. Observation: Observation

Example Answer List LL3995-9

Answer	Code	Score	Answer ID
Laser capture			LA26208-1
Microdissection			LA26209-9
Microdissection under microscopy			LA26210-7
Manual dissection			LA26221-4
Cored from block			LA26222-2
Whole tissue section employed			LA26223-0

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Τεχνική ανατομής:Type:Pt:Ιστός:Nom:* Synonyms: Type Τεχνική ανατομής
es-ES	Spanish (Spain)	Técnica de disección:Tipo:Punto temporal:Tejido:Nom:*
es-MX	Spanish (Mexico)	Técnica de disección:Tipo:Punto temporal:Tejido y frotis:Nominal:*
it-IT	Italian (Italy)	Tecnica di dissezione:Tipo:Pt:Tessuto:Nom:* Synonyms: Patologia Punto nel tempo (episodio) Tessuto & Strisci
zh-CN	Chinese (China)	切割方法:类型:时间点:组织与涂片:名义型:* Synonyms: 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答切割（解剖、剥离、剖分、切开、分解）方法（技术方法、技术、法）型时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片

85286-3 Promoter methylation testing method [Type] in Cancer specimen

Fully-Specified Name

Component: Promoter methylation testing method
Property: Type
Time: Pt
System: Cancer specimen
Scale: Nom
Method: *

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Example Answer List LL4352-2

Answer	Code	Score	Answer ID
Methylation-specific real-time polymerase chain reaction (MSP)			LA27157-9
Methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA)			LA27159-5
Pyrosequencing (PSQ)			LA27158-7
Other, Specify:			LA46-8

Member of these Panels

LOINC	Long Common Name
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μέθοδος δοκιμής μεθυλίωσης υποκινητή:Type:Pt:Δείγμα καρκίνου:Nom:* Synonyms: Type Μέθοδος Μέθοδος δοκιμής μεθυλίωσης υποκινητή
es-ES	Spanish (Spain)	Método para tesatr promotores de metilación:Tipo:Punto temporal:Muestra de cancer:Nom:*
es-MX	Spanish (Mexico)	Método de prueba de metilación del promotor:Tipo:Punto temporal:Espécimen de cáncer:Nominal:*
it-IT	Italian (Italy)	Metodo di test di metilazione di promoter:Tipo:Pt:Campione tumore:Nom:* Synonyms: Campione di tumore Neoplasia maligna Patologia Punto nel tempo (episodio)
zh-CN	Chinese (China)	启动子甲基化检测方法:类型:时间点:癌标本:名义型:* Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物启动子（启动子区）甲基化检测（检验、测定、测试）方法型方;法;办法;方式时刻;随机;随意;瞬间样品样本癌癌（癌症、癌变）标本（样本、样品、试样）试样

85069-3 Lab test method [Type]

Term Description

The lab test method code is used to report the specific test method used in the laboratory.

Fully-Specified Name

Component: Lab test method
Property: Type
Time: Pt
System: Specimen
Scale: Nom
Method: *

Basic Attributes

Class: MISC
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.58 (ADD)
Order vs. Observation: Observation

HL7^® Attributes

HL7^® Field ID: OBX-17

Member of these Panels

LOINC	Long Common Name
95405-7	Assay related variables panel [PhenX]
85905-8	Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
85735-9	Congenital rubella case report panel
102116-1	ESR1 gene mutation panel - Tissue by Molecular genetics method
102117-9	Gastrointestinal stromal tumor multigene mutation panel - Tissue by Molecular genetics method
96629-1	HLA-A and B and C (class I) typing panel - Blood or Tissue by Low resolution
96628-3	HLA-A and B and C (class I) typing panel - Blood or Tissue from Donor by Low resolution
92254-2	Microorganism identification and resistance pattern determination panel by Molecular genetics method
102118-7	Rhabdomyolysis and Metabolic myopathy multigene panel - Blood or Tissue by Molecular genetics method
102119-5	Skeletal muscle channelopathy multigene panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μέθοδος εξέτασης εργαστηρίου:Type:Pt:Δείγμα:Nom:* Synonyms: Type Μέθοδος Μέθοδος δοκιμής Μέθοδος εξέτασης εργαστηρίου
es-ES	Spanish (Spain)	Metodología de la prueba de laboratorio:Tipo:Punto temporal:Especimen:Nom:*
es-MX	Spanish (Mexico)	Método de prueba de laboratorio:Tipo:Punto temporal:Muestra:Nominal:*
fr-FR	French (France)	Méthode du laboratoire:Type:Ponctuel:Prélèvement:Résultat nominal:
it-IT	Italian (Italy)	Metodo test laboratorio:Tipo:Pt:Campione:Nom:* Synonyms: Metodo di test di laboratorio Miscellanea Punto nel tempo (episodio)
pl-PL	Polish (Poland)	Metoda badania laboratoryjnego:typ:punkt w czasie:próbka:cecha:*
zh-CN	Chinese (China)	实验室检验方法:类型:时间点:标本:名义型:* Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答受检物型实验室检验（实验室检验项目、实验室检测、实验室、检验项目、检验、化验、检测）方法方;法;办法;方式时刻;随机;随意;瞬间杂项;杂项类;杂项试验样品样本测试方法;检测方法;检验方法;化验方法;测定方法;分析方法;测量方法;检查方法试样

Related Codes

Code System	Code	Code Text	Code Version
https://www.phenxtoolkit.org	PX230201060000	PX230201_Adipocytokines_Assay_Type

85905-8

Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Active

33725-3 Tumor site

Term Description

Fully-Specified Name

Basic Attributes

Example Answer List LL4310-0

Member of these Panels

Language Variants Get Info

Related Names

33756-8 Polyp size greatest dimension

Fully-Specified Name

Basic Attributes

Member of these Panels

Language Variants Get Info

Related Names

Example Units

33757-6 Polyp size additional dimensions

Fully-Specified Name

Basic Attributes

Member of these Panels

Language Variants Get Info

Related Names

Example Units

33758-4 Polyp stalk length by CAP cancer protocols

Fully-Specified Name

Basic Attributes

Member of these Panels

Language Variants Get Info

Related Names

85298-8 Body structure included in specimen [Anatomy] in Specimen

Fully-Specified Name

Basic Attributes

Example Answer List LL4310-0

Member of these Panels

Language Variants Get Info

Related Names

85348-1 Procedure used to obtain tumor specimen [Type] in Specimen

Fully-Specified Name

Basic Attributes

Example Answer List LL4376-1

Member of these Panels

Language Variants Get Info

Related Names

84880-4 Position of rectal tumor in relation to anterior peritoneal reflection [Anatomy] in Tumor

Term Description

Fully-Specified Name

Basic Attributes

Preferred Answer List LL4072-6

Member of these Panels

Language Variants Get Info

Related Names

33728-7 Size.maximum dimension in Tumor

Fully-Specified Name

Basic Attributes

Member of these Panels

Language Variants Get Info

Related Names

Example Units

33729-5 Size additional dimension in Tumor

Fully-Specified Name

Basic Attributes

Member of these Panels

Language Variants Get Info

Related Names

Example Units

84879-6 Tumor perforation [Presence] by Macroscopy

Term Description

Fully-Specified Name

Basic Attributes

Example Answer List LL3950-4

Member of these Panels

Language Variants Get Info

Related Names

Third Party Copyright

33730-3 Resection completeness in Mesorectum Qualitative by Macroscopy

Term Description

Fully-Specified Name

Basic Attributes