85905-8
Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols
Active
33725-3 Tumor site
Term Description
The site in the body where the tumor is located. For example, in colorectal cancers, the tumor sites include the cecum, ascending or descending colon, hepatic flexure, splenic flexure, or rectum.
Fully-Specified Name
- Component
- Tumor site
- Property
- Anat
- Time
- Pt
- System
- Specimen
- Scale
- Nom
- Method
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 10199
Example Answer List LL4310-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Cecum | LA16833-8 | ||
| Ascending colon | LA16834-6 | ||
| Hepatic flexure | LA16835-3 | ||
| Transverse colon | LA16836-1 | ||
| Splenic flexure | LA16837-9 | ||
| Descending colon | LA16838-7 | ||
| Sigmoid colon | LA16839-5 | ||
| Rectosigmoid junction | LA26985-4 | ||
| Rectum | LA16840-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85904-1 | Cancer pathology panel - Breast cancer specimen by CAP cancer protocols |
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 98249-6 | Cancer pathology panel - Endometrial cancer specimen |
| 81186-9 | Gastric cancer pathology panel |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Nádor místo: |
| el-GR | Greek (Greece) | Θέση όγκου: Synonyms: Anat Nom PATH PATH.PROTOCOLS.GENER Pt Δείγμα Θέση όγκου |
| es-AR | Spanish (Argentina) | localización tumoral: |
| es-ES | Spanish (Spain) | Localización del tumor: |
| es-MX | Spanish (Mexico) | Sitio del tumor: |
| it-IT | Italian (Italy) | Tumore, sito: Synonyms: Anatomia Patologia Protocolli patologia - generale Punto nel tempo (episodio) Sito di neoplasia |
| nl-NL | Dutch (Netherlands) | tumorafmeting: |
| pt-BR | Portuguese (Brazil) | Local do tumor: Synonyms: Anatomy; |
| ru-RU | Russian (Russian Federation) | Опухоль локализация: Synonyms: Анатомия Номинальный; |
| tr-TR | Turkish (Turkey) | Tümör bölgesi: Synonyms: Spesmen |
| zh-CN | Chinese (China) | 肿瘤部位: Synonyms: 一般病理学原始记录; |
33756-8 Polyp size greatest dimension
Fully-Specified Name
- Component
- Polyp size greatest dimension
- Property
- Len
- Time
- Pt
- System
- Specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.70 (MIN)
- Change Reason
- Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Polyp velikost největší rozměr: |
| el-GR | Greek (Greece) | Μέγεθος πολύποδα μεγαλύτερη διάσταση: Synonyms: Len PATH PATH.PROTOCOLS.GENER Pt Qn Δείγμα Διαστάσεις Μέγεθος Μέγεθος πολύποδα μεγαλύτερη διάσταση |
| es-AR | Spanish (Argentina) | mayor dimensión del tamaño del pólipo: |
| es-ES | Spanish (Spain) | Tamaño mayor de dimensión del pólipo: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Tamaño del pólipo mayor dimensión: |
| it-IT | Italian (Italy) | Dimensione polipo, dimensione maggiore: Synonyms: Dimensione maggiore di dimensione polipo Lunghezza Patologia Protocolli patologia - generale Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | poliepgrootte grootste afmeting: Synonyms: lengte |
| pt-BR | Portuguese (Brazil) | Pólipo.maior dimensão de tamanho: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Полип размер наибольшее измерение: Synonyms: Длина Количественный порция; |
| tr-TR | Turkish (Turkey) | Polip büyüklüğü ne geniş boyut: Synonyms: Spesmen Süre |
| zh-CN | Chinese (China) | 息肉大小最大尺寸: Synonyms: 一般病理学原始记录; |
Example Units
| Unit | Source |
|---|---|
| cm | Example UCUM Units |
33757-6 Polyp size additional dimensions
Fully-Specified Name
- Component
- Polyp size additional dimensions
- Property
- Len
- Time
- Pt
- System
- Specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.70 (MIN)
- Change Reason
- Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Polyp velikost další rozměry: |
| el-GR | Greek (Greece) | Μέγεθος πολύποδα πρόσθετες διαστάσεις: Synonyms: Len PATH PATH.PROTOCOLS.GENER Pt Qn Δείγμα Μέγεθος Μέγεθος πολύποδα πρόσθετες διαστάσεις |
| es-AR | Spanish (Argentina) | dimensiones adicionales al tamaño del pólipo: |
| es-ES | Spanish (Spain) | Tamaño del pólipo dimensiones adicionales: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Dimensiones adicionales del tamaño del pólipo: |
| it-IT | Italian (Italy) | Dimensione polipo, dimensioni addizionali: Synonyms: Dimensioni addizionali di dimensione polipo Lunghezza Patologia Protocolli patologia - generale Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | poliepgrootte aanvullende afmetingen: Synonyms: lengte |
| pt-BR | Portuguese (Brazil) | Pólipo.dimensão de tamanho adicional: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Полип размер дополнительные измерения: Synonyms: Длина Количественный порция; |
| tr-TR | Turkish (Turkey) | Polip büyüklüğü ek boyutları: Synonyms: Spesmen Süre |
| zh-CN | Chinese (China) | 息肉大小附加维度: Synonyms: 一般病理学原始记录; |
Example Units
| Unit | Source |
|---|---|
| cm | Example UCUM Units |
33758-4 Polyp stalk length by CAP cancer protocols
Fully-Specified Name
- Component
- Polyp stalk length
- Property
- Prid
- Time
- Pt
- System
- Specimen
- Scale
- Nom
- Method
- CAP cancer protocols
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.61 (MIN)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Polyp stonek délka: |
| el-GR | Greek (Greece) | Μήκος μίσχου πολύποδα: Synonyms: Nom PATH PATH.PROTOCOLS.GENER Prid Pt Δείγμα Μήκος Μήκος μίσχου πολύποδα Πρωτόκολλα CAP για τον καρκίνο |
| es-AR | Spanish (Argentina) | largo del tallo de pólipo: |
| es-ES | Spanish (Spain) | Longitud del tallo de los pólipos: |
| es-MX | Spanish (Mexico) | Longitud del tallo del pólipo: |
| it-IT | Italian (Italy) | Polipo, lunghezza gambo: Synonyms: Lunghezza gambo di polipo Patologia Presenza o Identità Protocolli neoplasia maligna CAP Protocolli patologia - generale Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | poliep steellengte: |
| pt-BR | Portuguese (Brazil) | Comprimento do pedúnculo do pólipo: Synonyms: Len; |
| tr-TR | Turkish (Turkey) | Polip gizli uzunluğu: Synonyms: Spesmen Süre |
| zh-CN | Chinese (China) | 息肉茎长度: Synonyms: CAP 癌症方案; |
85298-8 Body structure included in specimen [Anatomy] in Specimen
Fully-Specified Name
- Component
- Body structure included in specimen
- Property
- Anat
- Time
- Pt
- System
- Specimen
- Scale
- Nom
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4310-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Cecum | LA16833-8 | ||
| Ascending colon | LA16834-6 | ||
| Hepatic flexure | LA16835-3 | ||
| Transverse colon | LA16836-1 | ||
| Splenic flexure | LA16837-9 | ||
| Descending colon | LA16838-7 | ||
| Sigmoid colon | LA16839-5 | ||
| Rectosigmoid junction | LA26985-4 | ||
| Rectum | LA16840-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Tělní struktura obsažená ve vzorku: |
| el-GR | Greek (Greece) | Σωματική δομή περιλαμβάνεται στο δείγμα: Synonyms: Anat Nom PATH Pt Δείγμα Σωματική δομή περιλαμβάνεται στο δείγμα |
| es-ES | Spanish (Spain) | estructura del cuerpo incluida en la muestra: |
| es-MX | Spanish (Mexico) | Estructura corporal incluida en la muestra.: |
| it-IT | Italian (Italy) | Parte anatomica inclusa nel campione: Synonyms: Anatomia Patologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | lichaamsstructur geïncludeerd in monster: |
| zh-CN | Chinese (China) | 包括在标本之中的身体结构: Synonyms: 供检查用的材料; |
85348-1 Procedure used to obtain tumor specimen [Type] in Specimen
Fully-Specified Name
- Component
- Procedure used to obtain tumor specimen
- Property
- Type
- Time
- Pt
- System
- Specimen
- Scale
- Nom
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4376-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Excision without image-guidance localization | LA27207-2 | ||
| Excision with image-guidance localization | LA27208-0 | ||
| Total mastectomy (including nipple and skin) | LA27209-8 | ||
| Colectomy | LA26037-4 | ||
| Hemicolectomy | LA15410-6 | ||
| Polypectomy | LA17735-4 | ||
| Other, Specify: | LA46-8 | ||
| Not specified | LA27211-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85904-1 | Cancer pathology panel - Breast cancer specimen by CAP cancer protocols |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Postup získání vzorku nádoru: |
| el-GR | Greek (Greece) | Διαδικασία που χρησιμοποιήθηκε για τη λήψη δείγματος όγκου: Synonyms: Nom PATH Pt Type Δείγμα Διαδικασία Διαδικασία που χρησιμοποιήθηκε για τη λήψη δείγματος όγκου |
| es-ES | Spanish (Spain) | Procemiento utilizado paraobtener muestra tumoral: |
| es-MX | Spanish (Mexico) | Procedimiento utilizado para obtener una muestra de tumor: |
| it-IT | Italian (Italy) | Procedura usata per ottenere il campione di tumore: Synonyms: Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 用于获取肿瘤标本的操作项目: Synonyms: 供检查用的材料; |
84880-4 Position of rectal tumor in relation to anterior peritoneal reflection [Anatomy] in Tumor
Term Description
For rectal tumors, the relationship of the tumor in relation to the anterior peritoneal reflection may be classified as entirely above, astride (at), or entirely below the level of the anterior peritoneal reflection. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Fully-Specified Name
- Component
- Position of rectal tumor in relation to anterior peritoneal reflection
- Property
- Anat
- Time
- Pt
- System
- Tumor
- Scale
- Nom
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Order vs. Observation
- Observation
Preferred Answer List LL4072-6
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Entirely above | LA26481-4 | ||
| Astride | LA26482-2 | ||
| Entirely below | LA26483-0 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Nádor rekta poloha vzhledem k přední reflexi peritonea: |
| el-GR | Greek (Greece) | Θέση του όγκου του ορθού σε σχέση με την πρόσθια περιτοναϊκή ανάκλαση: Synonyms: Anat Nom PATH Pt Θέση Θέση του όγκου του ορθού σε σχέση με την πρόσθια περιτοναϊκή ανάκλαση Όγκος |
| es-ES | Spanish (Spain) | Posición del tumor rectal en relación con el reflejo peritoneal anterior.: |
| es-MX | Spanish (Mexico) | Posición del tumor rectal en relación con el reflejo peritoneal anterior: |
| it-IT | Italian (Italy) | Posizione del tumore rettale in relazione alla riflessione peritoneale anteriore: Synonyms: Anatomia Neoplasia Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 直肠肿瘤相对于前腹膜反折的位置: Synonyms: 分类型应答; |
33728-7 Size.maximum dimension in Tumor
Fully-Specified Name
- Component
- Size.max.dimension
- Property
- Len
- Time
- Pt
- System
- Tumor
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.70 (MIN)
- Change Reason
- Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 98249-6 | Cancer pathology panel - Endometrial cancer specimen |
| 81186-9 | Gastric cancer pathology panel |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Velikost.max.rozměr: |
| el-GR | Greek (Greece) | Μέγεθος.μέγιστη.διάσταση: Synonyms: Len PATH PATH.PROTOCOLS.GENER Pt Qn Διαστάσεις Μέγ Μέγεθος Μέγεθος.μέγιστη.διάσταση Όγκος |
| es-AR | Spanish (Argentina) | tamaño.máximo.dimensión: |
| es-ES | Spanish (Spain) | Tamaño.max.dimensión: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Size.max.dimension: |
| it-IT | Italian (Italy) | Dimensione.massima.dimensione: Synonyms: Lunghezza Massimo Neoplasia Patologia Protocolli patologia - generale Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | afmeting.max.dimensie: Synonyms: lengte |
| pt-BR | Portuguese (Brazil) | Tamanho.max.dimensão: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Размер.max.измерение: Synonyms: Длина Количественный Максимум Точка во времени; |
| tr-TR | Turkish (Turkey) | Büyüklük.maks.boyut: Synonyms: Süre |
| zh-CN | Chinese (China) | 大小.最大值.维度: Synonyms: 一般病理学原始记录; |
Example Units
| Unit | Source |
|---|---|
| cm | Example UCUM Units |
33729-5 Size additional dimension in Tumor
Fully-Specified Name
- Component
- Size.additional dimension
- Property
- Len
- Time
- Pt
- System
- Tumor
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.70 (MIN)
- Change Reason
- Removed method of "CAP cancer protocols" because this term is not a CAP cancer protocol-specific concept and can be used across various cancer protocols.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Velikost další rozměr: |
| el-GR | Greek (Greece) | Μέγεθος.επιπρόσθετη διάσταση: Synonyms: Len PATH PATH.PROTOCOLS.GENER Pt Qn Διαστάσεις Μέγεθος Μέγεθος.επιπρόσθετη διάσταση Όγκος |
| es-AR | Spanish (Argentina) | tamaño.dimensión adicional: |
| es-ES | Spanish (Spain) | Tamaño.dimensión adicional: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Tamaño dimensión adicional: |
| it-IT | Italian (Italy) | Dimensione.dimensione addizionale: Synonyms: Dimensione addizionale di dimensione Lunghezza Neoplasia Patologia Protocolli patologia - generale Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | afmeting.aanvullende dimensie: Synonyms: lengte |
| pt-BR | Portuguese (Brazil) | Tamanho.dimensão adicional: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Размер.дополнительное измерение: Synonyms: Длина Количественный Точка во времени; |
| tr-TR | Turkish (Turkey) | Büyüklük.ek boyut: Synonyms: Süre |
| zh-CN | Chinese (China) | 大小.附加维度: Synonyms: 一般病理学原始记录; |
Example Units
| Unit | Source |
|---|---|
| cm | Example UCUM Units |
84879-6 Tumor perforation [Presence] by Macroscopy
Term Description
The macroscopic finding for the presence or absence of perforation through the tumor. Perforation through the tumor into the peritoneal cavity is a well established adverse prognostic factor in colonic and rectal cancer. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Fully-Specified Name
- Component
- Tumor perforation
- Property
- PrThr
- Time
- Pt
- System
- Tumor
- Scale
- Ord
- Method
- Macroscopy
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Order vs. Observation
- Observation
Example Answer List LL3950-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
| Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Nádor perforace: |
| el-GR | Greek (Greece) | Διάτρηση όγκου: Synonyms: Ord PATH PrThr Pt Διάτρηση όγκου Μακροσκοπική εξέταση Όγκος |
| es-ES | Spanish (Spain) | Perforación tumoral: |
| es-MX | Spanish (Mexico) | Perforación del tumor: |
| it-IT | Italian (Italy) | Tumore, perforazione: Synonyms: Neoplasia Patologia Perforazione da parte del tumore Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 肿瘤穿孔: Synonyms: 依次型; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
33730-3 Resection completeness in Mesorectum Qualitative by Macroscopy
Term Description
This term represents the macroscopic completeness of the surgical mesorectum excision in patients undergoing surgery for rectal cancer. Complete excision, known as total mesorectal excision or TME, is associated with decreased risk of local recurrence and increased rate of 5-year survival. PMID: 27697315
Fully-Specified Name
- Component
- Resection completeness
- Property
- Find
- Time
- Pt
- System
- Mesorectum
- Scale
- Ord
- Method
- Macroscopy
Basic Attributes
- Class
- PATH.PROTOCOLS.GENER
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Removed Method of "CAP cancer protocol" and copyright because this is not a CAP-specific concept and added "Method" of macroscopy. Also added an answer list and term description.
- Order vs. Observation
- Observation
Example Answer List LL4568-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Not applicable | LA4720-4 | ||
| Complete | LA26032-5 | ||
| Near complete | LA27882-2 | ||
| Incomplete | LA7341-6 | ||
| Cannot be determined | LA11899-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Resekce úplnost: |
| el-GR | Greek (Greece) | Πληρότητα εκτομής: Synonyms: Ord PATH PATH.PROTOCOLS.GENER Pt Εύρεση Μακροσκοπική εξέταση Μεσοορθό Πληρότητα εκτομής |
| es-AR | Spanish (Argentina) | integridad de resección: |
| es-ES | Spanish (Spain) | Resección completa: |
| es-MX | Spanish (Mexico) | Completitud de la resección: |
| it-IT | Italian (Italy) | Resezione, completezza: Synonyms: Completezza di resezione Osservazione Patologia Protocolli patologia - generale Punto nel tempo (episodio) |
| pt-BR | Portuguese (Brazil) | Resecção perfeita: Synonyms: Finding; |
| zh-CN | Chinese (China) | 切除术彻底性: Synonyms: 一般病理学原始记录; |
84882-0 Histologic type in Colorectal cancer specimen by WHO classification
Term Description
Colorectal cancer histologic type based on the current World Health Organization (WHO) classification. Colonrectal tumor types include adenocarcinoma, mucinous adenocarcinoma, signet-ring cell carcinoma, small cell carcinoma, squamous cell carcinoma, adenosquamous carcinoma, medullary carcinoma, and others. https://publications.iarc.fr/Book-And-Report-Series/Iarc-Handbooks-Of-Cancer-Prevention/Colorectal-Cancer-Screening-2019
Fully-Specified Name
- Component
- Histologic type
- Property
- Type
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- WHO classification
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.72 (MIN)
- Change Reason
- Release 2.72: DefinitionDescription: updated the url;
- Order vs. Observation
- Observation
Preferred Answer List LL4073-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Adenoma, NOS | LA15390-0 | ||
| Tubular adenoma, NOS | LA26485-5 | ||
| Villous adenoma, NOS | LA26486-3 | ||
| Tubulovillous adenoma, NOS | LA26487-1 | ||
| Glandular intraepithelial neoplasia, low grade | LA26488-9 | ||
| Glandular intraepithelial neoplasia, high grade | LA26489-7 | ||
| Sessile serrated adenoma/polyp | LA26490-5 | ||
| Serrated polyposis | LA26491-3 | ||
| Traditional serrated adenoma | LA26492-1 | ||
| Adenocarcinoma, NOS | LA26493-9 | ||
| Cribriform comedo-type adenocarcinoma | LA26494-7 | ||
| Medullary carcinoma, NOS | LA26495-4 | ||
| Micropapillary carcinoma | LA26496-2 | ||
| Colloid carcinoma | LA26497-0 | ||
| Serrated adenocarcinoma | LA26498-8 | ||
| Signet ring cell carcinoma | LA15444-5 | ||
| Adenosquamous carcinoma | LA15446-0 | ||
| Spindle cell carcinoma, NOS | LA26501-9 | ||
| Undifferentiated carcinoma | LA15447-8 | ||
| Neuroendocrine tumor G1 (NET G1)/Carcinoid | LA26504-3 | ||
| Neuroendocrine tumor G2 (NET G2) | LA26505-0 | ||
| Neuroendocrine carcinoma, NOS | LA26506-8 | ||
| Large cell neuroendocrine carcinoma | LA26100-0 | ||
| Small cell neuroendocrine carcinoma | LA26101-8 | ||
| Mixed adenoneuroendocrine carcinoma | LA26102-6 | ||
| Enterochromaffin cell (EC), serotonin-producing | LA26510-0 | ||
| L cell, Glucagon-like peptide-producing and PP/PYY-producing NETs | LA26512-6 | ||
| Leiomyoma, NOS | LA26513-4 | ||
| Lipoma, NOS | LA26514-2 | ||
| Angiosarcoma | LA26515-9 | ||
| Gastrointestinal stromal tumor, malignant | LA26516-7 | ||
| Kaposi sarcoma | LA26517-5 | ||
| Leiomyosarcoma, NOS | LA26518-3 | ||
| Schwannoma, NOS | LA26519-1 | ||
| Perineurioma, NOS | LA26520-9 | ||
| Ganglioneuroma | LA26521-7 | ||
| Granular cell tumor, NOS | LA26522-5 | ||
| Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) | LA26523-3 | ||
| Mantle cell lymphoma | LA26524-1 | ||
| Diffuse large B-cell lymphoma (DLBCL), NOS | LA26525-8 | ||
| Burkitt lymphoma, NOS | LA26526-6 | ||
| B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma | LA26527-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Histologický typ: |
| el-GR | Greek (Greece) | Ιστολογικός τύπος: Synonyms: Nom PATH Pt Type Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Ιστολογικός τύπος Καρκίνος Ταξινόμηση WHO |
| es-ES | Spanish (Spain) | Tipo histológico: |
| es-MX | Spanish (Mexico) | Tipo histológico: |
| it-IT | Italian (Italy) | Tipo istologico: Synonyms: Campione di tumore Classificazione OMS Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 组织学类型: Synonyms: WHO 分类法; |
85281-4 Intratumoral lymphocytic response in Cancer specimen Qualitative by Light microscopy
Fully-Specified Name
- Component
- Intratumoral lymphocytic response
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4371-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| None Copyright http://snomed.info/sct ID:260413007 None (qualifier value) | LA137-2 | ||
| Mild to moderate | LA15008-8 | ||
| Marked | LA17968-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Odpověď intratumorální lymfocytární: |
| el-GR | Greek (Greece) | Ενδοογκική λεμφοκυτταρική απόκριση: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Ενδοογκική λεμφοκυτταρική απόκριση Εύρεση Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | respuesta linfocitica intratumoral: |
| es-MX | Spanish (Mexico) | Respuesta linfocítica intratumoral: |
| it-IT | Italian (Italy) | Risposta linfocitario intratumorale: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Odpowiedź limfocytarna wewnątrz guza nowotworowego: Synonyms: nowotwór |
| zh-CN | Chinese (China) | 肿瘤内部淋巴细胞反应: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85284-8 Peritumoral lymphocytic response in Cancer specimen Qualitative by Light microscopy
Fully-Specified Name
- Component
- Peritumoral lymphocytic response
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4371-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| None Copyright http://snomed.info/sct ID:260413007 None (qualifier value) | LA137-2 | ||
| Mild to moderate | LA15008-8 | ||
| Marked | LA17968-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Odpověď peritumorální lymfocytární: |
| el-GR | Greek (Greece) | Περιογκική λεμφοκυτταρική απόκριση: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Εύρεση Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Περιογκική λεμφοκυτταρική απόκριση |
| es-ES | Spanish (Spain) | respuesta linfocitica peritumoral: |
| es-MX | Spanish (Mexico) | Respuesta linfocítica peritumoral: |
| it-IT | Italian (Italy) | Reazione linfocitaria peritumorale: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Odpowiedź limfocytarna wokół guza nowotworowego: Synonyms: nowotwór |
| zh-CN | Chinese (China) | 肿瘤周围淋巴细胞反应: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85282-2 Mucinous fraction [Area Fraction] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Mucinous fraction
- Property
- AreaFr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mucinózní frakce: |
| el-GR | Greek (Greece) | Βλεννώδες κλάσμα: Synonyms: AreaFr PATH Pt Qn Βλεννώδες κλάσμα Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | fraccion mucinosa: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Fracción mucinosa: |
| it-IT | Italian (Italy) | Frazione mucinosa: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 黏液性组分: Synonyms: 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
84883-8 Deepest extent of tumor invasion [Type] in Colorectal cancer specimen
Term Description
The deepest extent or maximum degree of local tumor invasion into or through the bowel wall. Results are based on the T component of the TNM staging system, as outlined in the AJCC Cancer Staging Manual. PMID: 20180029 Invasion depths include submucosa (pT1), muscularis propria (pT2), through muscularis propria into pericolorectal tissues (pT3), penetrating the visceral peritoneum (pT4a), and directly invading or adherent to other organs or structures (pT4b). This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Fully-Specified Name
- Component
- Deepest extent of tumor invasion
- Property
- Type
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Change Reason
- This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol. In addition, the Scale was corrected from Ord to Nom.
- Order vs. Observation
- Observation
Preferred Answer List LL4074-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Tumor invades submucosa | pT1 | LA26528-2 | |
| Tumor invades muscularis propria | pT2 | LA26529-0 | |
| Tumor invades through the muscularis propria into pericolorectal tissues | pT3 | LA26530-8 | |
| Tumor penetrates the visceral peritoneum | pT4a | LA26531-6 | |
| Tumor directly invades or is adherent to other organs or structures | pT4b | LA26532-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Nádor nejhlubší rozsah invaze: |
| el-GR | Greek (Greece) | Βαθύτερη έκταση διήθησης όγκου: Synonyms: Nom PATH Pt Type Βαθύτερη έκταση διήθησης όγκου Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος |
| es-ES | Spanish (Spain) | Extensión más profunda de la invasión tumoral: |
| es-MX | Spanish (Mexico) | Extensión más profunda de la invasión tumoral: |
| it-IT | Italian (Italy) | Estensione più profonda dell'invasione tumorale: Synonyms: Campione di tumore Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 肿瘤侵袭最深范围: Synonyms: 供检查用的材料; |
85283-0 Organ tumor is adherent to [Anatomy] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Organ tumor is adherent to
- Property
- Anat
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4370-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Coccyx | LA27201-5 | ||
| Duodenum | LA16846-0 | ||
| Pancreas | LA4654-5 | ||
| Stomach | LA4476-3 | ||
| Urinary bladder | LA9371-1 | ||
| Uterus | LA4447-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Orgánový nádor je adherentní k: |
| el-GR | Greek (Greece) | Όργανο στο οποίο είναι προσκολλημένος ο όγκος: Synonyms: Anat Nom PATH Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Όργανο στο οποίο είναι προσκολλημένος ο όγκος |
| es-ES | Spanish (Spain) | tumor adherente a organo: |
| es-MX | Spanish (Mexico) | El tumor de órgano se adhiere a: |
| it-IT | Italian (Italy) | Tumore d'organo aderente a: Synonyms: Anatomia Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 器官肿瘤粘附于: Synonyms: 供检查用的材料; |
85275-6 Adjacent structure invaded by tumor [Anatomy] in Colorectal cancer specimen by Light microscopy
Part Descriptions
LP247832-1 Adjacent structure invaded by tumor
The organ or other body structure invaded by a tumor. For example, breast tumors can invade the chest wall, skeletal muscle and skin, and colon cancer can invade many organs or structures, including the pancreas, urinary bladder, ovary, uterus, and coccyx.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Adjacent structure invaded by tumor
- Property
- Anat
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH.HISTO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4370-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Coccyx | LA27201-5 | ||
| Duodenum | LA16846-0 | ||
| Pancreas | LA4654-5 | ||
| Stomach | LA4476-3 | ||
| Urinary bladder | LA9371-1 | ||
| Uterus | LA4447-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Sousední struktura napadená nádorem: |
| el-GR | Greek (Greece) | Παρακείμενη δομή με εισβολή του όγκου: Synonyms: Anat Nom PATH PATH.HISTO Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Παρακείμενη δομή με εισβολή του όγκου |
| es-ES | Spanish (Spain) | Estructura adyacente invadida por el tumor: Synonyms: Histologia |
| es-MX | Spanish (Mexico) | Estructura adyacente invadida por tumor: |
| it-IT | Italian (Italy) | Struttura adiacente invasa dal tumore: Synonyms: Anatomia Campione di tumore Istologia Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 肿瘤所侵犯的邻近结构: Synonyms: 供检查用的材料; |
85290-5 Surgical margin tumor involvement [Presence] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Surgical margin tumor involvement
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4381-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding) | LA27250-2 | ||
| Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding) | LA27251-0 | ||
| Cannot be assessed | LA27144-7 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize okraj zasažení nádorem: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Συμμετοχή εγχειρητικού ορίου όγκου |
| es-ES | Spanish (Spain) | afetación tumoral del margen quirúrgico: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 手术边缘肿瘤累及: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85276-4 Closest surgical margin when all margins are uninvolved [Type] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Closest surgical margin when all margins are uninvolved
- Property
- Type
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4348-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Proximal margin | LA27145-4 | ||
| Distal margin | LA27149-6 | ||
| Deep margin | LA27146-2 | ||
| Circumferential margin | LA27147-0 | ||
| Mucosal margin | LA27150-4 | ||
| Mesenteric margin | LA27148-8 | ||
| Other, Specify: | LA46-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize nejbližší okraj když nejsou žádné okraje zasaženy: |
| el-GR | Greek (Greece) | Πλησιέστερο εγχειρητικό περιθώριο όταν δεν εμπλέκεται κανένα όριο: Synonyms: Nom PATH Pt Type Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Πλησιέστερο εγχειρητικό περιθώριο όταν δεν εμπλέκεται κανένα όριο |
| es-ES | Spanish (Spain) | Margen quirúrgico más cercano cuando todos los márgenes no están involucrados: |
| es-MX | Spanish (Mexico) | Margen quirúrgico más cercano cuando todos los márgenes no están afectados: |
| it-IT | Italian (Italy) | Margine di resezione chirurgica più vicino quando tutti i margini sono dissecati: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 并未累及所有边缘时的最近手术边缘: Synonyms: 供检查用的材料; |
85278-0 Distance of carcinoma from closest surgical margin when all margins are uninvolved [Length] in Cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Distance of carcinoma from closest surgical margin when all margins are uninvolved
- Property
- Len
- Time
- Pt
- System
- Cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Karcinom vzdálenost od nejbližšího okraje excize když nejsou žádné okraje zasaženy: |
| el-GR | Greek (Greece) | Απόσταση του καρκινώματος από το πλησιέστερο εγχειρητικό όριο όταν δεν εμπλέκεται κανένα όριο: Synonyms: Len PATH Pt Qn Απόσταση του καρκινώματος από το πλησιέστερο εγχειρητικό όριο όταν δεν εμπλέκεται κανένα όριο Δείγμα Δείγμα καρκίνου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Πλησιέστερο εγχειρητικό περιθώριο όταν δεν εμπλέκεται κανένα όριο |
| es-ES | Spanish (Spain) | Distancia del carcinoma al margen quirurgico mas próximo cuando todos los margenes no estan afectados: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Distancia del carcinoma desde el margen quirúrgico más cercano cuando todos los márgenes no están afectados: |
| it-IT | Italian (Italy) | Distanza del carcinoma dal margine chirurgico più vicino quando tutti i margini non sono coinvolti: Synonyms: Campione di tumore Lunghezza Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 当并未累及所有边缘时癌相距最近手术边缘的距离: Synonyms: 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| mm | Example UCUM Units |
85295-4 Surgical margin tumor involvement.proximal [Presence] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Surgical margin tumor involvement.proximal
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4381-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding) | LA27250-2 | ||
| Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding) | LA27251-0 | ||
| Cannot be assessed | LA27144-7 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize okraj zasažení nádorem.proximální: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου.εγγύς: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.εγγύς |
| es-ES | Spanish (Spain) | Margen quirúrgico afectado del tumor. Proximal: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico proximal: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore.prossimale: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.prossi Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 外科手术边界肿瘤累及.近端: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85292-1 Surgical margin tumor involvement.distant [Presence] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Surgical margin tumor involvement.distant
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4381-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding) | LA27250-2 | ||
| Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding) | LA27251-0 | ||
| Cannot be assessed | LA27144-7 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize okraj zasažení nádorem.vzdálené: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου.απομακρυσμένο: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.απομακρυσμένο |
| es-ES | Spanish (Spain) | Margen quirúrgico afectado del tumor.Distante: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico distante: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore.distante: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.distan Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 外科手术边界肿瘤累及.远处: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
84885-3 Surgical margin tumor involvement.circumferential [Presence] in Colorectal cancer specimen
Term Description
The result for whether or not the circumferential resection margin (CRM) on the non-peritonealized surface of the resected specimen is involved. CRM involvement (1mm or less distance between tumor and CRM) is an important predictor of local recurrence in rectal carcinoma. PMID: 16328130 This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Fully-Specified Name
- Component
- Surgical margin tumor involvement.circumferential
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Change Reason
- This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
- Order vs. Observation
- Observation
Example Answer List LL4076-7
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Involved | LA26536-5 | ||
| Not involved | LA26535-7 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize okraj zasažení nádorem.obvodové: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου.περιμετρικό: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.περιμετρικό |
| es-ES | Spanish (Spain) | Margen quirúrgico afectado del tumor.Circunferencial: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico circunferencial: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore.circonferenziale: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.circon Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 外科手术边界肿瘤累及.周围: Synonyms: 供检查用的材料; |
85293-9 Surgical margin tumor involvement.mesenteric [Presence] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Surgical margin tumor involvement.mesenteric
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4381-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding) | LA27250-2 | ||
| Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding) | LA27251-0 | ||
| Cannot be assessed | LA27144-7 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Chirurgický okraj nádoru zasažení.mezenterické: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου.μεσεντέριο: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.μεσεντέριο |
| es-ES | Spanish (Spain) | afectacion tumoral del margen quirúrgico mesenterico: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico mesentérico: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore.mesenterico: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.mesent Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 手术边缘肿瘤累及.肠系膜: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85291-3 Surgical margin tumor involvement.deep [Presence] in Colorectal cancer specimen by Light microscopy
Part Descriptions
LP73459-7 Surgical margin tumor involvement.deep
Biopsies of the skin are done in order to remove skin lesions and determine the specific diagnosis. Surgical margins are the boundaries of the excised specimen, and in the case of a skin biopsy, the deep margin is the one furthest away from the skin surface. A margin is considered 'positive' if it contains neoplastic cells and indicates that additional treatment may be needed besides the excision. Deeper excisions are more invasive but are associated with diminished chances for the tumor's reoccurrence. PMID: 25484385
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Surgical margin tumor involvement.deep
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4381-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Surgical margin not involved by tumor Copyright http://snomed.info/sct ID:55182004 Surgical margin uninvolved by tumor (finding) | LA27250-2 | ||
| Surgical margin involved by tumor Copyright http://snomed.info/sct ID:370109009 Surgical margin involved by tumor (finding) | LA27251-0 | ||
| Cannot be assessed | LA27144-7 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize okraj zasažení nádorem.hluboké: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου.εν τω βάθει: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.εν τω βάθει |
| es-ES | Spanish (Spain) | Margen quirúrgico afectado del tumor.Profundidad: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico profundo: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore.profondo: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.profon Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 外科手术边界肿瘤累及.深部: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85294-7 Surgical margin tumor involvement.mucosal [Identifier] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Surgical margin tumor involvement.mucosal
- Property
- Prid
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4350-6
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Cannot be assessed | LA27144-7 | ||
| Uninvolved by invasive carcinoma | LA27151-2 | ||
| Involved by invasive carcinoma | LA27152-0 | ||
| Uninvolved by adenoma | LA27153-8 | ||
| Involved by adenoma | LA27154-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Excize okraj zasažení nádorem.slizniční: |
| el-GR | Greek (Greece) | Συμμετοχή εγχειρητικού ορίου όγκου.βλεννογόνου: Synonyms: Nom PATH Prid Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Συμμετοχή εγχειρητικού ορίου όγκου Συμμετοχή εγχειρητικού ορίου όγκου.βλεννογόνου |
| es-ES | Spanish (Spain) | Margen quirúrgico afectado del tumor. Mucosa: |
| es-MX | Spanish (Mexico) | Afectación tumoral del margen quirúrgico mucosa: |
| it-IT | Italian (Italy) | Coinvolgimento margine chirurgico tumore.mucosale: Synonyms: Campione di tumore Coinvolgimento margine chirurgico neoplasia.mucosa Microscopia ottica Neoplasia maligna Patologia Presenza o Identità Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 外科手术边界肿瘤累及.粘膜: Synonyms: 供检查用的材料; |
85277-2 Distance of carcinoma from closest mucosal margin when all mucosal margins are uninvolved [Length] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Distance of carcinoma from closest mucosal margin when all mucosal margins are uninvolved
- Property
- Len
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Karcinom vzdálenost od nejbližšího slizničního okraje když nejsou žádné okraje sliznice zasaženy: |
| el-GR | Greek (Greece) | Απόσταση του καρκινώματος από το πλησιέστερο όριο του βλεννογόνου όταν δεν εμπλέκεται κανένα όριο του βλεννογόνου: Synonyms: Len PATH Pt Qn Απόσταση του καρκινώματος από το πλησιέστερο όριο του βλεννογόνου όταν δεν εμπλέκεται κανένα όριο του βλεννογόνου Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | Distancia del carcinoma al margen mucoso mas próximo cuando todos los margenes no estan afectados: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Distancia del carcinoma al margen de la mucosa más cercano cuando todos los márgenes de la mucosa no están afectados: |
| it-IT | Italian (Italy) | Distanza di carcinoma dal margine più vicino della mucosa quando tutti margini della mucosa non sono coinvolti: Synonyms: Campione di tumore Lunghezza Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 当并未累及所有黏膜边缘时癌相距最近黏膜边缘的距离: Synonyms: 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| mm | Example UCUM Units |
85288-9 Radial position of closest uninvolved mucosal margin [Angle] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Radial position of closest mucosal margin when mucosal margin uninvolved by invasive carcinoma
- Property
- Angle
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH.HISTO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Radiální poloha nejbližšího nezasaženého okraje sliznice: |
| el-GR | Greek (Greece) | Ακτινική θέση του πλησιέστερου ορίου του βλεννογόνου όταν το όριο του βλεννογόνου δε συμμετέχει στο διηθητικό καρκίνωμα: Synonyms: PATH PATH.HISTO Pt Qn Ακτινική θέση του πλησιέστερου ορίου του βλεννογόνου όταν το όριο του βλεννογόνου δε συμμετέχει στο διηθητικό καρκίνωμα Γωνία Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Θέση Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | Posición radial del margen mucoso más cercano cuando el margen mucoso no está afectado por carcinoma invasivo: Synonyms: Cuantitativo Histologia |
| es-MX | Spanish (Mexico) | Posición radial del margen mucoso no afectado más cercano: |
| it-IT | Italian (Italy) | Posizione radiale del margine mucosale più vicino quando il margine mucosale non è interessato dal carcinoma invasivo: Synonyms: Campione di tumore Istologia Microscopia ottica Neoplasia maligna Patologia Posizione radiale del margine mucosale più vicino Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 当浸润性癌并未累及黏膜边缘时最近黏膜边缘的径向位置: Synonyms: 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| deg | Example UCUM Units |
85287-1 Radial position of closest mucosal margin involved by invasive carcinoma [Angle] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Radial position of closest mucosal margin involved by invasive carcinoma
- Property
- Angle
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH.HISTO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Karcinom invazivní radiální poloha nejbližšího zasaženého okraje sliznice: |
| el-GR | Greek (Greece) | Ακτινική θέση του πλησιέστερου ορίου βλεννογόνου που συμμετέχει στο διηθητικό καρκίνωμα: Synonyms: PATH PATH.HISTO Pt Qn Ακτινική θέση του πλησιέστερου ορίου βλεννογόνου που συμμετέχει στο διηθητικό καρκίνωμα Γωνία Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Θέση Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | Posición radial del margen mucoso más cercano involucrado por carcinoma invasivo: Synonyms: Cuantitativo Histologia |
| es-MX | Spanish (Mexico) | Posición radial del margen mucoso más cercano involucrado por carcinoma invasivo: |
| it-IT | Italian (Italy) | Posizione radiale del margine mucosale più vicino interessato dal carcinoma invasivo: Synonyms: Campione di tumore Istologia Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 当浸润性癌累及黏膜边缘时最近黏膜边缘的径向位置: Synonyms: 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| deg | Example UCUM Units |
85289-7 Signet ring cells/cells in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Signet ring cells/Cells
- Property
- NFr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Buňky tvaru pečetního prstenu/100 buněk: |
| el-GR | Greek (Greece) | Κύτταρα δίκην σφραγιστήρος δακτυλίου/κύτταρα: Synonyms: NFr PATH Pt Qn Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Κύτταρα Κύτταρα δίκην σφραγιστήρος δακτυλίου Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | celulas en anillo de sello/células: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Células en anillo de sello / 100 células: |
| it-IT | Italian (Italy) | Cellule anello con sigillo/cellule: Synonyms: Campione di tumore Frazione numerica Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Komórki sygnetowate/komórki: Synonyms: nowotwór |
| zh-CN | Chinese (China) | 印戒细胞/细胞: Synonyms: SRC; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
85296-2 Tumor budding [Presence] in Cancer specimen by Light microscopy
Part Descriptions
LP247844-6 Tumor budding
Tumor budding is the presence of single cells or clusters of less than five cells scattered in the stroma at the margin of an invasive tumor. Tumor budding may be a predictor of regional lymph node involvement and is associated with worse outcomes, including cancer recurrence, in patients with colorectal cancer. PMID: 22669453
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Tumor budding
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL744-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Nádor pučení: |
| el-GR | Greek (Greece) | Εκβλάστηση όγκου: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Εκβλάστηση όγκου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | "yemas " tumorales: |
| es-MX | Spanish (Mexico) | Brote del tumor: |
| it-IT | Italian (Italy) | Tumor budding: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 肿瘤出芽: Synonyms: 供检查用的材料; |
85297-0 Tumor buds [#/area] in Cancer specimen by Light microscopy
Part Descriptions
LP247845-3 Tumor buds
Tumor budding is the presence of single cells or clusters of less than five cells scattered in the stroma at the margin of an invasive tumor. Tumor budding may be a predictor of regional lymph node involvement and is associated with worse outcomes, including cancer recurrence, in patients with colorectal cancer. PMID: 22669453
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Tumor buds
- Property
- Naric
- Time
- Pt
- System
- Cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (MIN)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Nádor pupeny: |
| el-GR | Greek (Greece) | Καρκινικές εκβλαστήσεις: Synonyms: Naric PATH Pt Qn Δείγμα Δείγμα καρκίνου Καρκινικές εκβλαστήσεις Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | "yemas" de tumor: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Brotes tumorales: |
| it-IT | Italian (Italy) | Tumor buds: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Numero Areico (per area) Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 肿瘤芽: Synonyms: 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| /[HPF] | Example UCUM Units |
21894-1 Regional lymph nodes examined [#] Specimen
Term Description
Records the total number of regional lymph nodes that were removed and examined by the pathologist. Beginning with tumors diagnosed on or after January 1, 2004, this item is a component of the Collaborative Stage system. Tumors diagnosed from 1988 through 2003, this item is a part of the 10-digit EOD [779], detailed site-specific codes for anatomic EOD.
This data item serves as a quality measure of the pathologic and surgical evaluation and treatment of the patient... NAACCR Data Standards and Data Dictionary Version 11
Fully-Specified Name
- Component
- Regional lymph nodes examined
- Property
- Num
- Time
- Pt
- System
- Specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- TUMRRGT
- Type
- Clinical
- First Released
- Version 1.0m
- Last Updated
- Version 2.56 (MAJ)
- Change Reason
- Changed the system from "Cancer.XXX" to "Specimen".
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85904-1 | Cancer pathology panel - Breast cancer specimen by CAP cancer protocols |
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81186-9 | Gastric cancer pathology panel |
| 49083-9 | North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 11 panel |
| 59852-4 | North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 12 panel |
| 74293-2 | Oncology plan of care and summary - recommended CDA set |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Εξετασθέντες περιφερικοί λεμφαδένες: Synonyms: Pt Qn TUMRRGT Αρ. Δείγμα Εξετασθέντες λεμφαδένες Εξετασθέντες περιφερικοί λεμφαδένες |
| es-AR | Spanish (Argentina) | ganglios linfáticos regionales examinados: |
| es-ES | Spanish (Spain) | Nodos linfáticos regionales examinados: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Examen de los ganglios linfáticos regionales: |
| it-IT | Italian (Italy) | Linfonodi regionali esaminati: Synonyms: Numero (conta) Punto nel tempo (episodio) Registro tumori |
| ru-RU | Russian (Russian Federation) | Региональные лимфоузлы исследованы: Synonyms: Количественный Количество порция; |
| tr-TR | Turkish (Turkey) | İncelenmiş bölgesel lenf nodları: Synonyms: Spesmen |
| zh-CN | Chinese (China) | 已检查的局部淋巴结: Synonyms: NAACCR 肿瘤登记; |
Example Units
| Unit | Source |
|---|---|
| {#} | Example UCUM Units |
21893-3 Regional lymph nodes positive [#] Specimen
Term Description
Records the exact number of regional nodes examined by the pathologist and found to contain metastases. Beginning with tumors diagnosed on or after January 1, 2004, this item is a component of the Collaborative Stage system. Tumors diagnosed from 1988 through 2003,this item is part of the 10-digit EOD [779], detailed site-specific codes for anatomic EOD.
This data item is necessary for pathologic staging, and it serves as a quality measure for pathology reports and the extent of the surgical evaluation and treatment of the patient. NAACCR Data Standards and Data Dictionary Version 11
Fully-Specified Name
- Component
- Regional lymph nodes positive
- Property
- Num
- Time
- Pt
- System
- Specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- TUMRRGT
- Type
- Clinical
- First Released
- Version 1.0m
- Last Updated
- Version 2.61 (MIN)
- Change Reason
- Changed the system from "Cancer.XXX" to "Specimen".
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81186-9 | Gastric cancer pathology panel |
| 49083-9 | North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 11 panel |
| 59852-4 | North American Association of Central Cancer Registries, Inc (NAACCR, Inc) version 12 panel |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Θετικοί περιφερικοί λεμφαδένες: Synonyms: Pt Qn TUMRRGT Αρ. Δείγμα Θετικοί περιφερικοί λεμφαδένες |
| es-AR | Spanish (Argentina) | ganglios linfáticos regionales positivos: |
| es-ES | Spanish (Spain) | Nodos linfáticos regionales positivos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Ganglios linfáticos regionales positivos: |
| it-IT | Italian (Italy) | Linfonodi regionali positivi: Synonyms: Numero (conta) Punto nel tempo (episodio) Registro tumori |
| ru-RU | Russian (Russian Federation) | Региональные лимфоузлы положительный: Synonyms: Количественный Количество порция; |
| zh-CN | Chinese (China) | 局部淋巴结阳性: Synonyms: NAACCR 肿瘤登记; |
Example Units
| Unit | Source |
|---|---|
| {#} | Example UCUM Units |
84888-7 Intramural vein invasion [Presence] in Colorectal cancer specimen by Light microscopy
Part Descriptions
LP222091-3 Intramural vein invasion
Venous invasion (VI) is a well-established prognostic indicator in colorectal cancers and associated with an increase in risk of distant metastases. PMID: 26933769 VI can be classified as either intramural venous invasion (IMVI) or extramural venous invasion (EMVI). IMVI is when a tumor cells are confined to veins within the bowel wall. EMVI is when tumor cells are present in veins outside the bowel wall. Either one or both may be present. The presence of EMVI is a strong predictor of adverse outcome. PMCID: PMC4283716
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Intramural vein invasion
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Change Reason
- This term is still in Trial status and upon further review, we added "Microscopy.light" as method to align with similar terms and since this cancer pathology observation is detected by light microscopy.
- Order vs. Observation
- Observation
Example Answer List LL748-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Not identified | LA11902-6 | ||
| Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Žíla intramurální invaze: |
| el-GR | Greek (Greece) | Ενδοτοιχωματική φλεβική διήθηση: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Ενδοτοιχωματική φλεβική διήθηση Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | Invasión venosa intramural: |
| es-MX | Spanish (Mexico) | Invasión de venas intramurales: |
| it-IT | Italian (Italy) | Invasione vena intramurale: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 壁内静脉侵袭: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
84889-5 Extramural vein invasion [Presence] in Colorectal cancer specimen by Light microscopy
Part Descriptions
LP222092-1 Extramural vein invasion
Venous invasion (VI) is a well-established prognostic indicator in colorectal cancers and associated with an increase in risk of distant metastases. PMID: 26933769 VI can be classified as either intramural venous invasion (IMVI) or extramural venous invasion (EMVI). IMVI is when a tumor cells are confined to veins within the bowel wall. EMVI is when tumor cells are present in veins outside the bowel wall. Either one or both may be present. The presence of EMVI is a strong predictor of adverse outcome. PMCID: PMC4283716
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Extramural vein invasion
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Change Reason
- This term is still in Trial status and upon further review, we added "Microscopy.light" as method to align with similar terms and since this cancer pathology observation is detected by light microscopy.
- Order vs. Observation
- Observation
Example Answer List LL748-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Not identified | LA11902-6 | ||
| Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 84907-5 | Cancer pathology panel - Colorectal cancer specimen |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Žíla extramurální invaze: |
| el-GR | Greek (Greece) | Εξωτοιχωματική φλεβική διήθηση: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Εξωτοιχωματική φλεβική διήθηση Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | Invasión venosa extramural: |
| es-MX | Spanish (Mexico) | Invasión de venas extramurales: |
| it-IT | Italian (Italy) | Invasione extramurale della vena: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 壁外静脉侵袭: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
92837-4 Perineural invasion [Presence] in Cancer specimen
Fully-Specified Name
- Component
- Perineural invasion
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL1937-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
| Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81186-9 | Gastric cancer pathology panel |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Perineurální invaze: |
| el-GR | Greek (Greece) | Περινευρική διήθηση: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Καρκίνος Περινευρική διήθηση |
| es-ES | Spanish (Spain) | Invasión perineural: |
| es-MX | Spanish (Mexico) | Invasión perineural: |
| it-IT | Italian (Italy) | Invasione perineurale: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 神经周围侵袭: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
84886-1 Satellite nodules [Presence] in Colorectal cancer specimen
Term Description
The presence or absence of isolated satellite nodules (extramural tumor deposits) within the mesocolic and mesorectal fat. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Part Descriptions
LP222090-5 Satellite nodules
A satellite nodule is a cluster of neoplastic cells that are less than 2cm from the primary tumor. [NCBI Books: NBK65951]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Satellite nodules
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.69 (MIN)
- Change Reason
- This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
- Order vs. Observation
- Observation
Example Answer List LL3950-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
| Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Uzliny satelitní: |
| el-GR | Greek (Greece) | Δορυφορικά οζίδια: Synonyms: Ord PATH PrThr Pt Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Δορυφορικά οζίδια Καρκίνος |
| es-ES | Spanish (Spain) | Nódulos satélites: |
| es-MX | Spanish (Mexico) | Nódulos satélite: |
| it-IT | Italian (Italy) | Noduli satelliti: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 卫星结节: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85508-0 Satellite nodules [#] in Colorectal cancer specimen by Light microscopy
Part Descriptions
LP222090-5 Satellite nodules
A satellite nodule is a cluster of neoplastic cells that are less than 2cm from the primary tumor. [NCBI Books: NBK65951]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Satellite nodules
- Property
- Num
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Qn
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Uzliny satelitní: |
| el-GR | Greek (Greece) | Δορυφορικά οζίδια: Synonyms: PATH Pt Qn Αρ. Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Δορυφορικά οζίδια Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός |
| es-ES | Spanish (Spain) | Nódulos satélites: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Nódulos satélite: |
| it-IT | Italian (Italy) | Noduli satelliti: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 卫星结节: Synonyms: 个数; |
Example Units
| Unit | Source |
|---|---|
| {#} | Example UCUM Units |
84891-1 Tumor response to neoadjuvant therapy
Term Description
The response of the tumor to neoadjuvant treatment, such as chemotherapy and radiotherapy. Chemotherapy and/or radiotherapy before resection is associated with significant downstaging and improved prognosis. These specimens require close gross examination and additional blocking to demonstrate tumor. The degree of tumor regression has been shown to correlate with prognosis. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Fully-Specified Name
- Component
- Response to neoadjuvant therapy
- Property
- PrThr
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.71 (MIN)
- Change Reason
- This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
- Order vs. Observation
- Observation
Example Answer List LL4077-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| No prior treatment | LA26537-3 | ||
| Complete response (Grade 0 - No viable cancer cells) | LA26538-1 | ||
| Moderate response (Grade 1 - Single cells or small groups of cancer cells) | LA26539-9 | ||
| Mminimal response (Grade 2 - Residual cancer outgrown by fibrosis) | LA26540-7 | ||
| Poor response (Grade 3 - Minimal or no tumor kill; extensive) | LA26541-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Neoadjuvantní terapie odpověď: |
| el-GR | Greek (Greece) | Ανταπόκριση στη νεοεπικουρική θεραπεία: Synonyms: Ord PATH PrThr Pt Ανταπόκριση στη νεοεπικουρική θεραπεία Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος |
| es-ES | Spanish (Spain) | Respuesta a la terapia neoadyuvante: |
| es-MX | Spanish (Mexico) | Respuesta a la terapia neoadyuvante: |
| it-IT | Italian (Italy) | Risposta a terapia neoadiuvante: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 对新辅助疗法的反应: Synonyms: 供检查用的材料; |
85285-5 Polyp in which invasive carcinoma arose [Type] in Colorectal cancer specimen by Light microscopy
Fully-Specified Name
- Component
- Polyp in which invasive carcinoma arose
- Property
- Type
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Microscopy.light
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Preferred Answer List LL4351-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| None identified | LA11904-2 | ||
| Tubular adenoma | LA15387-6 | ||
| Villous adenoma | LA15389-2 | ||
| Tubular villous adenoma | LA15388-4 | ||
| Traditional serrated adenoma | LA26492-1 | ||
| Sessile serrated adenoma | LA27155-3 | ||
| Hamartomatous polyp | LA27156-1 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Polyp kde vznikl invazivní karcinom: |
| el-GR | Greek (Greece) | Πολύποδας στον οποίο εμφανίστηκε το διηθητικό καρκίνωμα: Synonyms: Nom PATH Pt Type Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μικρoσκόπιση Μικροσκόπηση.φωτός Πολύποδας στον οποίο εμφανίστηκε το διηθητικό καρκίνωμα |
| es-ES | Spanish (Spain) | Polipo en el que se origina el carcinoma: |
| es-MX | Spanish (Mexico) | Pólipo en el que surgió el carcinoma invasivo: |
| it-IT | Italian (Italy) | Polipo in cui è cresciuto il carcinoma invasivo: Synonyms: Campione di tumore Microscopia ottica Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 其中发生浸润性癌的息肉: Synonyms: 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81317-0 Additional pathological findings [Identifier] in Specimen
Term Description
Additional pathological findings identified in the specimen. For example, in gastric cancers, additional finding may include non-neoplastic pathologies such as gastritis, helicobacter infection, intestinal metaplasia, dysplasia, gastric polyps, Barrett's mucosa (for those specimens with esophagus) and others.
Fully-Specified Name
- Component
- Additional pathological findings
- Property
- Prid
- Time
- Pt
- System
- Specimen
- Scale
- Nom
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.63 (MIN)
- Order vs. Observation
- Observation
Example Answer List LL4009-8
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Gastritis | LA26033-3 | ||
| Helicobacter infection | LA26256-0 | ||
| Intestinal metaplasia | LA26257-8 | ||
| Gastric polyps | LA26258-6 | ||
| Barrett's mucosa | LA26259-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Další patologické nálezy: |
| el-GR | Greek (Greece) | Πρόσθετα παθολογικά ευρήματα: Synonyms: Nom PATH Prid Pt Δείγμα Πρόσθετα παθολογικά ευρήματα |
| es-ES | Spanish (Spain) | Hallazgos patológicos adicionales: |
| es-MX | Spanish (Mexico) | Hallazgos patológicos adicionales: |
| it-IT | Italian (Italy) | Ulteriori osservazioni patologiche: Synonyms: Patologia Presenza o Identità Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | additionele pathologische bevinding: |
| ru-RU | Russian (Russian Federation) | Дополнительные патологические находки: Synonyms: Дополнительные патологоанатомические находки Номинальный; |
| tr-TR | Turkish (Turkey) | Ek patolojik bolgular: Synonyms: Spesmen |
| zh-CN | Chinese (China) | 额外的病理学发现: Synonyms: 供检查用的材料; |
81691-8 MLH-1 Ag [Presence] in Cancer specimen by Immune stain
Part Descriptions
LP68388-5 MLH-1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), also known as MLH1, is a human gene located on Chromosome 3. It is a gene commonly associated with hereditary nonpolyposis colorectal cancer.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- MLH-1 Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.82 (NAM)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Example Answer List LL3993-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Intact nuclear expression | LA26197-6 | ||
| Loss of nuclear expression | LA26198-4 | ||
| Undetermined | LA14100-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | DNA mismatch repair protein Mlh1: |
| el-GR | Greek (Greece) | MLH-1 Αντιγόνο: Synonyms: MLH-1 Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | MLH-1 Antígeno: |
| es-MX | Spanish (Mexico) | Proteína de reparación de desajustes de ADN Mlh1: |
| fr-FR | French (France) | MLH-1 Ag: |
| it-IT | Italian (Italy) | MLH-1, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Naprawa niesparowanych zasad w DNA białko Mlh1: Synonyms: Białko Mlh1 związane z naprawą błędnie sparowanych zasad azotowych w DNA Kwas deoksyrybonukleinowy nowotwór System naprawy błędnie sparowanych zasad azotowych w DNA; |
| zh-CN | Chinese (China) | MLH-1 抗原: Synonyms: Ⅰ Ag I MLH-1 Ag MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); |
81692-6 MSH-2 Ag [Presence] in Cancer specimen by Immune stain
Fully-Specified Name
- Component
- MSH-2 Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.82 (NAM)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Example Answer List LL3993-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Intact nuclear expression | LA26197-6 | ||
| Loss of nuclear expression | LA26198-4 | ||
| Undetermined | LA14100-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | DNA mismatch repair protein Msh2: |
| el-GR | Greek (Greece) | MSH-2 Αντιγόνο: Synonyms: MSH-2 Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | MSH-2 Antígeno: |
| es-MX | Spanish (Mexico) | Proteína de reparación de desajustes de ADN Msh2: |
| fr-FR | French (France) | MSH-2 Ag: |
| it-IT | Italian (Italy) | MSH-2, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | MSH-2 Ag: Synonyms: Antygen MSH-2 nowotwór |
| zh-CN | Chinese (China) | MSH-2 抗原: Synonyms: Ⅱ Ag II MSH-2 Ag 供检查用的材料; |
81693-4 MSH-6 Ag [Presence] in Cancer specimen by Immune stain
Fully-Specified Name
- Component
- MSH-6 Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.82 (NAM)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Example Answer List LL3993-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Intact nuclear expression | LA26197-6 | ||
| Loss of nuclear expression | LA26198-4 | ||
| Undetermined | LA14100-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | DNA mismatch repair protein Msh6: |
| el-GR | Greek (Greece) | MSH-6 Αντιγόνο: Synonyms: MSH-6 Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | MSH-6 Antígeno: |
| es-MX | Spanish (Mexico) | Proteína de reparación de desajustes de ADN Msh6: |
| fr-FR | French (France) | MSH-6 Ag: |
| it-IT | Italian (Italy) | MSH-6, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | MSH-6 Ag: Synonyms: Antygen MSH-6 nowotwór |
| zh-CN | Chinese (China) | MSH-6 抗原: Synonyms: Ag MSH-6 Ag 供检查用的材料; |
81694-2 PMS2 Ag [Presence] in Cancer specimen by Immune stain
Fully-Specified Name
- Component
- PMS2 Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.82 (NAM)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because DNA mismatch repair testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Example Answer List LL3993-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Intact nuclear expression | LA26197-6 | ||
| Loss of nuclear expression | LA26198-4 | ||
| Undetermined | LA14100-4 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Endonukleáza PMS2 opravující chybné párování: |
| el-GR | Greek (Greece) | Ενδονουκλεάση επιδιόρθωσης ασυμφωνίας PMS2: Synonyms: Ord PATH PrThr Pt Ανοσολογική χρώση Δείγμα Δείγμα καρκίνου Ενδονουκλεάση επιδιόρθωσης ασυμφωνίας PMS2 Καρκίνος |
| es-ES | Spanish (Spain) | Endonucleasa PMS2 de reparación de errores: |
| es-MX | Spanish (Mexico) | Reparación de desajustes endonucleasa PMS2: |
| it-IT | Italian (Italy) | PMS2, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 错配修复内切核酸酶 PMS2: Synonyms: 供检查用的材料; |
81711-4 Microsatellite instability marker panel - Cancer specimen
Part Descriptions
LP212222-6 Microsatellite instability marker panel
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker panel
- Property
- -
- Time
- Pt
- System
- Cancer specimen
- Scale
- -
- Method
Basic Attributes
- Class
- PANEL.PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Order
- Panel Type
- Panel
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity markery nestability panel: |
| el-GR | Greek (Greece) | Πίνακας δεικτών μικροδορυφορικής αστάθειας: Synonyms: - PANEL.PATH PATH Pt Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορική αστάθεια Πίνακας δεικτών μικροδορυφορικής αστάθειας |
| es-ES | Spanish (Spain) | Panel de marcadores de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Panel marcador de inestabilidad de microsatélites: |
| it-IT | Italian (Italy) | Marcatore di instabilità dei microsatelliti, panel: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Panel Marcatore di instabilità dei microsatelliti Patologia Punto nel tempo (episodio) Set di prescrizione per patologia |
| zh-CN | Chinese (China) | 微卫星不稳定性标记组套: Synonyms: MSI 供检查用的材料; |
81696-7 Microsatellite instability markers assessed [#] in Cancer specimen
Fully-Specified Name
- Component
- Microsatellite instability markers assessed
- Property
- Num
- Time
- Pt
- System
- Cancer specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability posouzené: |
| el-GR | Greek (Greece) | Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας: Synonyms: PATH Pt Qn Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας Αρ. Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcadores evaluados de inestabilidad de microsatélites: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Marcadores de inestabilidad de microsatélites evaluados: |
| it-IT | Italian (Italy) | Marcatori di instabilità dei microsatelliti valutati: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 所评估的微卫星不稳定性标记: Synonyms: MSI 个数; |
Example Units
| Unit | Source |
|---|---|
| {#} | Example UCUM Units |
81697-5 Microsatellite instability marker BAT25 in Cancer specimen Qualitative
Part Descriptions
LP212210-1 Microsatellite instability marker BAT25
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker BAT25
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability BAT25: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας BAT25: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας BAT25 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador BAT25 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites BAT25: |
| it-IT | Italian (Italy) | Marcatore BAT25 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 BAT25: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81698-3 Microsatellite instability marker BAT26 in Cancer specimen Qualitative
Part Descriptions
LP212211-9 Microsatellite instability marker BAT26
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker BAT26
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability BAT26: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας BAT26: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας BAT26 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador BAT26 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites BAT26: |
| it-IT | Italian (Italy) | Marcatore BAT26 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 BAT26: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81699-1 Microsatellite instability marker NR21 in Cancer specimen Qualitative
Part Descriptions
LP212212-7 Microsatellite instability marker NR21
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker NR21
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability NR21: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας NR21: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας NR21 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador NR21 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites NR21: |
| it-IT | Italian (Italy) | Marcatore NR21 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 NR21: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81700-7 Microsatellite instability marker NR24 in Cancer specimen Qualitative
Part Descriptions
LP212213-5 Microsatellite instability marker NR24
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker NR24
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability NR24: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας NR24: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας NR24 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador NR24 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites NR24: |
| it-IT | Italian (Italy) | Marcatore NR24 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 NR24: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81701-5 Microsatellite instability marker MONO27 in Cancer specimen Qualitative
Part Descriptions
LP212214-3 Microsatellite instability marker MONO27
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker MONO27
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability MONO27: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας MONO27: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας MONO27 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | MarcadorMONO27 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites MONO27: |
| it-IT | Italian (Italy) | MarcatoreMONO27 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 MONO27: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81702-3 Microsatellite instability marker D2S123 in Cancer specimen Qualitative
Part Descriptions
LP212215-0 Microsatellite instability marker D2S123
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker D2S123
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability D2S123: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας D2S123: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας D2S123 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador D2S123 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites D2S123: |
| it-IT | Italian (Italy) | Marcatore D2S123 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 D2S123: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81703-1 Microsatellite instability marker D5S346 in Cancer specimen Qualitative
Part Descriptions
LP212216-8 Microsatellite instability marker D5S346
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker D5S346
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability D5S346: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας D5S346: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας D5S346 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador D5S346 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites D5S346: |
| it-IT | Italian (Italy) | Marcatore D5S346 di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 D5S346: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81704-9 Microsatellite instability marker D17S250 in Cancer specimen Qualitative
Part Descriptions
LP212217-6 Microsatellite instability marker D17S250
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability marker D17S250
- Property
- Find
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL1057-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| Unstable | LA14123-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelity marker nestability D17S250: |
| el-GR | Greek (Greece) | Δείκτης μικροδορυφορικής αστάθειας D17S250: Synonyms: Ord PATH Pt Δείγμα Δείγμα καρκίνου Δείκτης μικροδορυφορικής αστάθειας D17S250 Εύρεση Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Marcador 17S250 de inestabilidad de microsatélites: |
| es-MX | Spanish (Mexico) | Marcador de inestabilidad de microsatélites D17S250: |
| it-IT | Italian (Italy) | Marcatore D17S250di instabilità dei microsatelliti: Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Osservazione Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 微卫星不稳定性标记 D17S250: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81709-8 Microsatellite markers exhibiting instability [#] in Cancer specimen
Part Descriptions
LP212220-0 Microsatellite markers exhibiting instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite markers exhibiting instability
- Property
- Num
- Time
- Pt
- System
- Cancer specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Markery mikrosatelitů signalizující nestabilitu: |
| el-GR | Greek (Greece) | Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια: Synonyms: PATH Pt Qn Αρ. Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια |
| es-ES | Spanish (Spain) | Marcadores de inestabilidad de microsatelites: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Marcadores de microsatélites que presentan inestabilidad: |
| it-IT | Italian (Italy) | Marcatori di microsatelliti che dimostrano instabilità: Synonyms: Campione di tumore Neoplasia maligna Numero (conta) Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 表现不稳定性的微卫星标记: Synonyms: 个数; |
Example Units
| Unit | Source |
|---|---|
| {#} | Example UCUM Units |
81708-0 Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen
Part Descriptions
LP212220-0 Microsatellite markers exhibiting instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
LP212221-8 Microsatellite instability markers assessed
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite markers exhibiting instability/Microsatellite instability markers assessed
- Property
- NFr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Qn
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Markery mikrosatelitů signalizující nestabilitu/hodnocené markery nestability mikrosatelitů: |
| el-GR | Greek (Greece) | Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια/Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας: Synonyms: NFr PATH Pt Qn Αξιολογηθέντες δείκτες μικροδορυφορικής αστάθειας Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορική αστάθεια Μικροδορυφορικοί δείκτες που εμφανίζουν αστάθεια |
| es-ES | Spanish (Spain) | Marcadores de inestabilidad de microsatelites/Marcadores de inestabilidad de microsatélites evaluados: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Marcadores de microsatélites que presentan inestabilidad / Marcadores de inestabilidad de microsatélites evaluados: |
| it-IT | Italian (Italy) | Marcatori di microsatelliti che dimostrano instabilità/Marcatori di instabilità dei microsatelliti valutati: Synonyms: Campione di tumore Frazione numerica Instabilità dei microsatelliti Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 表现不稳定性的微卫星标记/所评估的微卫星不稳定性标记: Synonyms: MSI 供检查用的材料; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
81695-9 Microsatellite instability [Interpretation] in Cancer specimen Qualitative
Part Descriptions
LP36464-3 Microsatellite instability
The appearance of abnormally long or short microsatellites in an individual's DNA is referred to as microsatellite instability. Microsatellite instability (MSI) is a condition manifested by damaged DNA due to defects in the normal DNA repair process. Sections of DNA called microsatellites, which consist of a sequence of repeating units of 1-6 base pairs in length, become unstable and can shorten or lengthen. Microsatellites are also known as simple sequence repeats (SSRs).
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
LP36464-3 Microsatellite instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Microsatellite instability
- Property
- Imp
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL3994-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Stable | LA14122-8 | ||
| MSI-L Microsatellite instability - low | LA26202-4 | ||
| MSI-H Microsatellite instability - high | LA26203-2 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 81711-4 | Microsatellite instability marker panel - Cancer specimen |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Mikrosatelitová nestabilita: |
| el-GR | Greek (Greece) | Μικροδορυφορική αστάθεια: Synonyms: Imp Ord PATH Pt Δείγμα Δείγμα καρκίνου Καρκίνος Μικροδορυφορική αστάθεια |
| es-ES | Spanish (Spain) | Inestabilidad microsatelite: |
| es-MX | Spanish (Mexico) | Inestabilidad de microsatélites: |
| fr-FR | French (France) | Microsatellite instabilité: |
| it-IT | Italian (Italy) | Microsatelliti, instabilità: Synonyms: Campione di tumore Impressione/interpretazione di studio Instabilità dei microsatelliti Neoplasia maligna Patologia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Niestabilność mikrosatelitarna: Synonyms: MSI nowotwór |
| zh-CN | Chinese (China) | 微卫星不稳定性: Synonyms: MSI 供检查用的材料; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
58416-9 MLH1 gene methylation [Presence] in Blood or Tissue by Molecular genetics method
Part Descriptions
LP99240-1 MLH1 gene methylation
MLH1 gene methylation has been associated with many kinds of cancers with microsatellite instability
Source: Regenstrief LOINC
LP124510-1 gene methylation
DNA methylation is essential during embryonic development, and patterns of DNA methylation are generally transmitted to daughter cells with a high fidelity. In cancer, aberrant DNA methylation patterns are found in two distinct forms: hypermethylation and hypomethylation. Hypermethylation is one of the major epigenetic modifications that repress transcription via the promoter region of tumor suppressor genes. Hypermethylation typically occurs at CpG islands in the promoter region and is associated with gene inactivation. Hypomethylation, linked to chromosomal instability and loss of imprinting, arises earlier and occurs throughout the progression of cancer.
More specifically, methylated DNA can bind to methyl-CpG-binding domain proteins (MBDs), which recruit additional proteins such as histone deacetylases and other chromatin remodeling proteins that modify histones to form compact, inactive chromatin, termed silent chromatin. Loss of methyl-CpG-binding protein 2 (MeCP2) has been implicated in Rett syndrome; and methyl-CpG-binding domain protein 2 (MBD2) mediates the transcriptional silencing of hypermethylated genes in cancer. Research has suggested that long-term memory storage in humans may be regulated by DNA methylation.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- MLH1 gene methylation
- Property
- PrThr
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Ord
- Method
- Molgen
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.30
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- Release 2.72: PROPERTY: Updated Property from Arb to align with similar terms; SYSTEM: Updated System from Tiss as this test can be done using blood or tissue specimens;
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 15582
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen MLH1 methylace: |
| el-GR | Greek (Greece) | Μεθυλίωση γονιδίου MLH1: Synonyms: MOLPATH Ord PrThr Pt Αίμα Αίμα/Ιστός Γονίδιο Γονίδιο MLH1 Ιστός Μεθυλίωση γονιδίου MLH1 Μοριακή γενετική |
| es-ES | Spanish (Spain) | Metilación del gen MLH1: |
| es-MX | Spanish (Mexico) | Metilación del gen MLH1: |
| fr-FR | French (France) | MLH1 gène méthylation: |
| it-IT | Italian (Italy) | MLH1, metilazione gene: Synonyms: Gene MLH1 Genetica molecolare Metilazione del gene MLH1 Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
| nl-NL | Dutch (Netherlands) | MLH1 genmethylatie: Synonyms: MLH1 gen molgen |
| pl-PL | Polish (Poland) | MLH1 metylacja genu: Synonyms: diagnostyka molekularna Gen MLH1 Metylacja genu MLH1 |
| pt-BR | Portuguese (Brazil) | MLH1 gene metilação: Synonyms: MutL homolog 1, colon cancer, nonpolyposis type 2; |
| ru-RU | Russian (Russian Federation) | MLH1 ген метилирование: Synonyms: Кровь Кровь или Ткань Порядковый Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | MLH1 geni metilation: Synonyms: Mevcut |
| zh-CN | Chinese (China) | MLH1 基因甲基化: Synonyms: COCA2; |
83059-6 KRAS gene [VCF] in Cancer specimen by Sequencing
Term Description
This term is used to report the variant call file (VCF) associated with the KRAS gene sequence in a cancer specimen.
Part Descriptions
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
LP19732-4 KRAS gene
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- KRAS gene
- Property
- VCF
- Time
- Pt
- System
- Cancer specimen
- Scale
- Doc
- Method
- Sequencing
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.65 (MIN)
- Change Reason
- Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen KRAS: |
| el-GR | Greek (Greece) | Γονίδιο KRAS: Synonyms: Doc MOLPATH Pt VCF Αλληλούχιση Γονίδιο Γονίδιο KRAS Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | Gen KRAS: |
| es-MX | Spanish (Mexico) | Gen KRAS: |
| fr-FR | French (France) | KRAS gène: |
| it-IT | Italian (Italy) | KRAS, gene: Synonyms: Campione di tumore Gene KRAS Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file |
| pl-PL | Polish (Poland) | KRAS gen: Synonyms: Gen KRAS nowotwór |
| zh-CN | Chinese (China) | KRAS2 基因: Synonyms: Kirsten 大鼠肉瘤病毒 2; |
85509-8 KRAS gene mutations found [Identifier] in Colorectal cancer specimen by Targeted gene mutation analysis Nominal
Part Descriptions
LP19732-4 KRAS gene
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- KRAS gene mutations
- Property
- Prid
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Targeted gene mutation analysis
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.83 (NAM)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen KRAS cílená mutační analýza: |
| el-GR | Greek (Greece) | Γονίδιο KRAS στοχευμένη ανάλυση μεταλλάξεων: Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Γονίδιο Γονίδιο KRAS Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων |
| es-MX | Spanish (Mexico) | Análisis de mutaciones dirigidas al gen KRAS: |
| es-ES | Spanish (Spain) | Gen KRAS Analisis de mutaciones: |
| fr-FR | French (France) | KRAS gène mutation cible trouvée: |
| it-IT | Italian (Italy) | KRAS, gene analisi di mutazione mirata: Synonyms: Campione di tumore Gene KRAS Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | KRAS gen ukierunkowana analiza mutacji: Synonyms: Analiza mutacji genu KRAS diagnostyka molekularna Gen KRAS nowotwór wynik kategorialny |
| zh-CN | Chinese (China) | KRAS2 基因 突变分析: Synonyms: Kirsten 大鼠肉瘤病毒 2; |
83060-4 NRAS gene [VCF] in Cancer specimen by Sequencing
Term Description
This term is used to report the variant call file (VCF) associated with the NRAS gene sequence in a cancer specimen.
Part Descriptions
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
LP19749-8 NRAS gene
The NRAS gene (neuroblastoma RAS viral (v-ras) oncogene homolog) [HGNC Gene ID:7989] is located on chromosome 1p13.2. This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] [NCBI Gene ID:4893]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- NRAS gene
- Property
- VCF
- Time
- Pt
- System
- Cancer specimen
- Scale
- Doc
- Method
- Sequencing
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.65 (MIN)
- Change Reason
- Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen NRAS: |
| el-GR | Greek (Greece) | Γονίδιο NRAS: Synonyms: Doc MOLPATH Pt VCF Αλληλούχιση Γονίδιο Γονίδιο NRAS Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | Gen NRAS: |
| es-MX | Spanish (Mexico) | Gen NRAS: |
| fr-FR | French (France) | NRAS gène: |
| it-IT | Italian (Italy) | NRAS, gene: Synonyms: Campione di tumore Gene NRAS Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file |
| pl-PL | Polish (Poland) | NRAS gen: Synonyms: Gen NRAS nowotwór |
| zh-CN | Chinese (China) | NRAS 基因: Synonyms: Variant call file; |
85510-6 NRAS gene mutations found [Identifier] in Colorectal cancer specimen by Targeted gene mutation analysis Nominal
Part Descriptions
LP19749-8 NRAS gene
The NRAS gene (neuroblastoma RAS viral (v-ras) oncogene homolog) [HGNC Gene ID:7989] is located on chromosome 1p13.2. This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] [NCBI Gene ID:4893]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- NRAS gene mutations
- Property
- Prid
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Targeted gene mutation analysis
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.83 (NAM)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen NRAS cílená mutační analýza: |
| el-GR | Greek (Greece) | Γονίδιο NRAS στοχευμένη ανάλυση μεταλλάξεων: Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Γονίδιο Γονίδιο NRAS Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων |
| es-MX | Spanish (Mexico) | Análisis de mutaciones dirigidas al gen NRAS: |
| es-ES | Spanish (Spain) | Gen NRAS Analisis de mutaciones: |
| fr-FR | French (France) | NRAS gène mutation cible trouvée: |
| it-IT | Italian (Italy) | NRAS, gene analisi di mutazione mirata: Synonyms: Campione di tumore Gene NRAS Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | NRAS gen ukierunkowana analiza mutacji: Synonyms: Analiza mutacji genu NRAS diagnostyka molekularna Gen NRAS nowotwór wynik kategorialny |
| zh-CN | Chinese (China) | NRAS 基因 突变分析: Synonyms: v-ras 成神经细胞瘤 RAS 病毒癌基因同源基因; |
81705-6 BRAF protein Ag [Presence] in Cancer specimen by Immune stain
Part Descriptions
LP212224-2 Serine-threonine protein kinase B-raf
The BRAF gene (B-Raf proto-oncogene, serine/threonine kinase) [HGNC Gene ID:1097] is located on chromosome 7q34. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:673] Loss of the BRAF gene can be determined by various techniques, and loss of the protein, which is an indicator of gene mutation or deletion, can be detected by immunohistochemistry techniques.
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- Serine-threonine protein kinase B-raf Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.82 (NAM)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because BRAF protein immune staining is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL2038-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | BRAF protein: |
| el-GR | Greek (Greece) | Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf Αντιγόνο: Synonyms: B Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Θρεονίνη Καρκίνος Πρωτεΐνη Πρωτεϊνική κινάση Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf Σερίνη |
| es-ES | Spanish (Spain) | B-raf serina-treonina protein quinasa Antígeno: |
| es-MX | Spanish (Mexico) | Serina-treonina proteína quinasa B-raf: |
| it-IT | Italian (Italy) | Serina-treonina proteina chinasi B-raf, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia PKA Presenza o Soglia Proteina BRAF Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Kinaza białkowa serynowo-treoninowa B-raf Ag: Synonyms: nowotwór |
| zh-CN | Chinese (China) | 丝氨酸-苏氨酸蛋白激酶 B-raf 抗原: Synonyms: Ag B 型 Beta-羟丁氨酸; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
85299-6 BRAF V600E mutant protein Ag [Presence] in Cancer specimen by Immune stain
Fully-Specified Name
- Component
- Serine-threonine protein kinase B-raf V600E Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.82 (NAM)
- Order vs. Observation
- Observation
Example Answer List LL744-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | BRAF V600E mutovaný protein: |
| el-GR | Greek (Greece) | Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf V600E Αντιγόνο: Synonyms: B Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Θρεονίνη Καρκίνος Πρωτεΐνη Πρωτεϊνική κινάση Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf Πρωτεϊνική κινάση σερίνης-θρεονίνης B-raf V600E Σερίνη |
| es-ES | Spanish (Spain) | proteína serina/treonina quinasa B-Raf mutación V600E Antígeno: |
| es-MX | Spanish (Mexico) | Serina-treonina proteína quinasa B-raf V600E: |
| it-IT | Italian (Italy) | Serina-treonina proteina chinasi B-raf V600E, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia PKA Presenza o Soglia Proteina BRAF Proteina mutante BRAF V600E Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Serynowo-treoninowa kinaza białkowa B-raf V600E Ag: Synonyms: nowotwór |
| zh-CN | Chinese (China) | 丝氨酸-苏氨酸蛋白激酶 B-raf V600E 抗原: Synonyms: Ag B 型 Beta-羟丁氨酸; |
83061-2 BRAF gene [VCF] in Cancer specimen by Sequencing
Term Description
This term is used to report the variant call file (VCF) associated with the BRAF gene sequence in a cancer specimen.
Part Descriptions
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
LP71409-4 BRAF gene
The BRAF gene (B-Raf proto-oncogene, serine/threonine kinase) [HGNC Gene ID:1097] is located on chromosome 7q34. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:673] Loss of the BRAF gene can be determined by various techniques, and loss of the protein, which is an indicator of gene mutation or deletion, can be detected by immunohistochemistry techniques.
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- BRAF gene
- Property
- VCF
- Time
- Pt
- System
- Cancer specimen
- Scale
- Doc
- Method
- Sequencing
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.65 (MIN)
- Change Reason
- Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen BRAF: |
| el-GR | Greek (Greece) | Γονίδιο BRAF: Synonyms: Doc MOLPATH Pt VCF Αλληλούχιση Γονίδιο Γονίδιο BRAF Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | Gen BRAF: |
| es-MX | Spanish (Mexico) | Gen BRAF: |
| fr-FR | French (France) | BRAF gène: |
| it-IT | Italian (Italy) | BRAF, gene: Synonyms: Campione di tumore Gene BRAF Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file |
| pl-PL | Polish (Poland) | BRAF gen: Synonyms: Gen BRAF nowotwór |
| zh-CN | Chinese (China) | BRAF 基因: Synonyms: B-Raf; |
85511-4 BRAF gene mutations found [Identifier] in Colorectal cancer specimen by Targeted gene mutation analysis Nominal
Part Descriptions
LP71409-4 BRAF gene
The BRAF gene (B-Raf proto-oncogene, serine/threonine kinase) [HGNC Gene ID:1097] is located on chromosome 7q34. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:673] Loss of the BRAF gene can be determined by various techniques, and loss of the protein, which is an indicator of gene mutation or deletion, can be detected by immunohistochemistry techniques.
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- BRAF gene mutations
- Property
- Prid
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Targeted gene mutation analysis
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.83 (NAM)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen BRAF cílená mutační analýza: |
| el-GR | Greek (Greece) | Γονίδιο BRAF στοχευμένη ανάλυση μεταλλάξεων: Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Γονίδιο Γονίδιο BRAF Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων |
| es-MX | Spanish (Mexico) | Análisis de mutaciones dirigidas al gen BRAF: |
| es-ES | Spanish (Spain) | Gen BRAF Analisis de mutaciones: |
| fr-FR | French (France) | BRAF gène mutation cible trouvée: |
| it-IT | Italian (Italy) | BRAF, gene analisi di mutazione mirata: Synonyms: Campione di tumore Gene BRAF Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | BRAF gen ukierunkowana analiza mutacji: Synonyms: Analiza mutacji genu BRAF diagnostyka molekularna Gen BRAF nowotwór wynik kategorialny |
| zh-CN | Chinese (China) | BRAF 基因 突变分析: Synonyms: B-Raf; |
83062-0 PIK3CA gene [VCF] in Cancer specimen by Sequencing
Term Description
This term is used to report the variant call file (VCF) associated with the PIK3CA gene sequence in a cancer specimen.
Part Descriptions
LP101031-5 PIK3CA gene
The PIK3CA gene (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) [HGNC Gene ID:8975] is located on chromosome 3q26.3. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] [NCBI Gene ID:5290]
Source: National Center for Biotechnology Information (NCBI) Gene
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- PIK3CA gene
- Property
- VCF
- Time
- Pt
- System
- Cancer specimen
- Scale
- Doc
- Method
- Sequencing
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.65 (MIN)
- Change Reason
- Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen PIK3CA: |
| el-GR | Greek (Greece) | Γονίδιο PIK3CA: Synonyms: Doc MOLPATH Pt VCF Αλληλούχιση Γονίδιο Γονίδιο PIK3CA Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | Gen PIK3CA: |
| es-MX | Spanish (Mexico) | Gen PIK3CA: |
| fr-FR | French (France) | PIK3CA gène: |
| it-IT | Italian (Italy) | PIK3CA, gene: Synonyms: Campione di tumore Gene PIK3CA Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file |
| pl-PL | Polish (Poland) | PIK3CA gen: Synonyms: Gen PIK3CA nowotwór |
| zh-CN | Chinese (China) | PIK3CA 基因: Synonyms: MGC142161; |
85507-2 PIK3CA gene mutations found [Identifier] in Colorectal cancer specimen by Targeted gene mutation analysis Nominal
Part Descriptions
LP101031-5 PIK3CA gene
The PIK3CA gene (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) [HGNC Gene ID:8975] is located on chromosome 3q26.3. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] [NCBI Gene ID:5290]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- PIK3CA gene mutations
- Property
- Prid
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Targeted gene mutation analysis
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.83 (NAM)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen PIK3CA cílená mutační analýza: |
| el-GR | Greek (Greece) | Γονίδιο PIK3CA στοχευμένη ανάλυση μεταλλάξεων: Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Γονίδιο Γονίδιο PIK3CA Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων |
| es-MX | Spanish (Mexico) | Análisis de mutaciones dirigidas al gen PIK3CA: |
| es-ES | Spanish (Spain) | Gen PIK3CA Analisis de mutaciones: |
| fr-FR | French (France) | PIK3CA gène mutation cible trouvée: |
| it-IT | Italian (Italy) | PIK3CA, gene analisi di mutazione mirata: Synonyms: Campione di tumore Gene PIK3CA Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | PIK3CA gen ukierunkowana analiza mutacji: Synonyms: Analiza mutacji genu PIK3CA diagnostyka molekularna Gen PIK3CA nowotwór wynik kategorialny |
| zh-CN | Chinese (China) | PIK3CA 基因 突变分析: Synonyms: MGC142161; |
81706-4 Phosphatase and tensin homolog (PTEN) protein Ag [Presence] in Cancer specimen by Immune stain
Part Descriptions
LP212218-4 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques.
Source: Regenstrief LOINC, UniProt: P60484
Fully-Specified Name
- Component
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Ag
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- Immune stain
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.82 (NAM)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because PTEN protein immune staining is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL2038-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Protein Homolog fosfatázy a tensinu (PTEN): |
| el-GR | Greek (Greece) | 3-φωσφατάση της 3,4,5,-τριφωσφορικής φωσφατιδυλινοσιτόλης και διπλής ειδικότητας πρωτεϊνική φωσφατάση PTEN Αντιγόνο: Synonyms: 3-φωσφατάση της 3,4,5,-τριφωσφορικής φωσφατιδυλινοσιτόλης και διπλής ειδικότητας πρωτεϊνική φωσφατάση PTEN Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Καρκίνος Πρωτεΐνη Φωσφατιδυλινοσιτόλη |
| es-ES | Spanish (Spain) | Fosfatidilinositol 3,4,5-trifosfato 3-fosfatasa y especificidad dual de proteinfosfatasa PTEN Antígeno: |
| es-MX | Spanish (Mexico) | Fosfatidilinositol 3,4,5-trifosfato 3-fosfatasa y proteína fosfatasa de especificidad dual PTEN: |
| it-IT | Italian (Italy) | Fosfatidilinositolo 3,4,5- trifosfato 3-fosfato e proteina PTEN fosfatasi a doppia specificità, Ag: Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Fosfatydyloinozytol 3,4,5-trisfosforan 3-fosfataza i białkowa fosfataza o podwójnej specyficzności PTEN Ag: Synonyms: nowotwór |
| zh-CN | Chinese (China) | 磷脂酰肌醇 3,4,5-三磷酸 3-磷酸酯酶与双特异性蛋白磷酸酯酶 PTEN 抗原: Synonyms: Ⅲ Ag III PI; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
81710-6 PTEN gene [Presence] in Cancer specimen by FISH
Part Descriptions
LP61787-5 PTEN gene
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques.
Source: Regenstrief LOINC, UniProt: P60484
LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues.
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Source: Wikipedia, FISH
Fully-Specified Name
- Component
- PTEN gene
- Property
- PrThr
- Time
- Pt
- System
- Cancer specimen
- Scale
- Ord
- Method
- FISH
Basic Attributes
- Class
- MOLPATH.MISC
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MAJ)
- Change Reason
- Updated System from "Tiss" to "Cancer.XXX" because PTEN gene testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Observation
Example Answer List LL2038-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen PTEN: |
| el-GR | Greek (Greece) | Γονίδιο PTEN: Synonyms: MISC MOLPATH MOLPATH.MISC Ord PrThr Pt Γονίδιο Γονίδιο PTEN Δείγμα Δείγμα καρκίνου Καρκίνος Φθορίζουσα υβριδοποίηση in situ |
| es-ES | Spanish (Spain) | Gen PTEN: |
| es-MX | Spanish (Mexico) | Gen PTEN: |
| fr-FR | French (France) | PTEN gène: |
| it-IT | Italian (Italy) | PTEN, gene: Synonyms: Campione di tumore Gene PTEN Ibridazione in situ fluorescente (FISH) Miscellanea Miscellanea geni Neoplasia maligna Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | PTEN gen: Synonyms: fluorescencyjna hybrydyzacja in situ Gen PTEN nowotwór |
| zh-CN | Chinese (China) | PTEN 基因: Synonyms: Bannayan-Zonana 综合征（Bannayan-Zonana syndrome， |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to https://www.snomed.org/get-snomed or [email protected]<mailto:[email protected]>. This may incur a fee in SNOMED International non-Member countries.
83063-8 PTEN gene [VCF] in Cancer specimen by Sequencing
Term Description
This term is used to report the variant call file (VCF) associated with the PTEN gene sequence in a cancer specimen.
Part Descriptions
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
LP61787-5 PTEN gene
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques.
Source: Regenstrief LOINC, UniProt: P60484
Fully-Specified Name
- Component
- PTEN gene
- Property
- VCF
- Time
- Pt
- System
- Cancer specimen
- Scale
- Doc
- Method
- Sequencing
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.65 (MIN)
- Change Reason
- Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen PTEN: |
| el-GR | Greek (Greece) | Γονίδιο PTEN: Synonyms: Doc MOLPATH Pt VCF Αλληλούχιση Γονίδιο Γονίδιο PTEN Δείγμα Δείγμα καρκίνου Καρκίνος |
| es-ES | Spanish (Spain) | Gen PTEN: |
| es-MX | Spanish (Mexico) | Gen PTEN: |
| fr-FR | French (France) | PTEN gène: |
| it-IT | Italian (Italy) | PTEN, gene: Synonyms: Campione di tumore Gene PTEN Neoplasia maligna Patologia molecolare Punto nel tempo (episodio) Variant call file |
| pl-PL | Polish (Poland) | PTEN gen: Synonyms: Gen PTEN nowotwór |
| zh-CN | Chinese (China) | PTEN 基因: Synonyms: Bannayan-Zonana 综合征（Bannayan-Zonana syndrome， |
85506-4 PTEN gene mutations found [Identifier] in Colorectal cancer specimen by Targeted gene mutation analysis Nominal
Part Descriptions
LP61787-5 PTEN gene
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, also known as phosphate and tensin homolog or PTEN protein, is encoded by the PTEN gene on chromosome10q23.31. PTEN protein has multiple functions, including protein phosphatase and lipid phosphatase activity. The lipid phosphatase function is critical for its role as a tumor suppressor and modulating cell cycle progression and cell survival. It also plays a role in correct neuron positioning, dendritic development and synapse formation, and may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. Mutations in the PTEN gene are associated with multiple disorders, including PTEN hamartoma tumor syndromes, which include Cowden syndrome and Lhermitte-Duclos disease, squamous cell carcinoma of the head and neck, endometrial carcinoma, prostate cancer, and VACTERL with hydrocephalus. [UniProt: P60484] Loss of the PTEN gene can be determined by various techniques, including FISH, and loss of the PTEN protein can be detected by immunohistochemistry techniques.
Source: Regenstrief LOINC, UniProt: P60484
Fully-Specified Name
- Component
- PTEN gene mutations
- Property
- Prid
- Time
- Pt
- System
- Colorectal cancer specimen
- Scale
- Nom
- Method
- Targeted gene mutation analysis
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.83 (NAM)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen PTEN cílená mutační analýza: |
| el-GR | Greek (Greece) | Γονίδιο PTEN στοχευμένη ανάλυση μεταλλάξεων: Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Γονίδιο Γονίδιο PTEN Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του παχέος εντέρου Καρκίνος Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων |
| es-MX | Spanish (Mexico) | Análisis de mutaciones dirigidas al gen PTEN: |
| es-ES | Spanish (Spain) | Gen PTEN Analisis de mutaciones: |
| fr-FR | French (France) | PTEN gène mutation cible trouvée: |
| it-IT | Italian (Italy) | PTEN, gene analisi di mutazione mirata: Synonyms: Campione di tumore Gene PTEN Genetica molecolare Mutazione genica Neoplasia maligna Patologia molecolare Presenza o Identità Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | PTEN gen ukierunkowana analiza mutacji: Synonyms: Analiza mutacji genu PTEN diagnostyka molekularna Gen PTEN nowotwór wynik kategorialny |
| zh-CN | Chinese (China) | PTEN 基因 突变分析: Synonyms: Bannayan-Zonana 综合征（Bannayan-Zonana syndrome， |
81707-2 Dissection technique [Type] in Tissue
Part Descriptions
LP212219-2 Dissection technique
Various dissection methods for use with frozen or paraffin-embedded tissue sections exist that allow investigators to select the cells or areas of interest for further examination and to separate them cleanly from the background tissue. These methods include laser capture, microdissection under microscopy, manual dissection, and coring from block.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Dissection technique
- Property
- Type
- Time
- Pt
- System
- Tiss
- Scale
- Nom
- Method
- *
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.56 (MIN)
- Order vs. Observation
- Observation
Example Answer List LL3995-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Laser capture | LA26208-1 | ||
| Microdissection | LA26209-9 | ||
| Microdissection under microscopy | LA26210-7 | ||
| Manual dissection | LA26221-4 | ||
| Cored from block | LA26222-2 | ||
| Whole tissue section employed | LA26223-0 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Disekce technika: |
| el-GR | Greek (Greece) | Τεχνική ανατομής: Synonyms: * Nom PATH Pt Type Ιστός Τεχνική ανατομής |
| es-ES | Spanish (Spain) | Técnica de disección: |
| es-MX | Spanish (Mexico) | Técnica de disección: |
| it-IT | Italian (Italy) | Tecnica di dissezione: Synonyms: Patologia Punto nel tempo (episodio) Tessuto & |
| zh-CN | Chinese (China) | 切割方法: Synonyms: 分类型应答; |
85286-3 Promoter methylation testing method [Type] in Cancer specimen
Fully-Specified Name
- Component
- Promoter methylation testing method
- Property
- Type
- Time
- Pt
- System
- Cancer specimen
- Scale
- Nom
- Method
- *
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4352-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Methylation-specific real-time polymerase chain reaction (MSP) | LA27157-9 | ||
| Methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) | LA27159-5 | ||
| Pyrosequencing (PSQ) | LA27158-7 | ||
| Other, Specify: | LA46-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Methylace promotoru metoda testování: |
| el-GR | Greek (Greece) | Μέθοδος δοκιμής μεθυλίωσης υποκινητή: Synonyms: * Nom PATH Pt Type Δείγμα Δείγμα καρκίνου Καρκίνος Μέθοδος Μέθοδος δοκιμής μεθυλίωσης υποκινητή |
| es-ES | Spanish (Spain) | Método para tesatr promotores de metilación: |
| es-MX | Spanish (Mexico) | Método de prueba de metilación del promotor: |
| it-IT | Italian (Italy) | Metodo di test di metilazione di promoter: Synonyms: Campione di tumore Neoplasia maligna Patologia Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | 启动子甲基化检测方法: Synonyms: 供检查用的材料; |
85069-3 Lab test method [Type]
Term Description
The lab test method code is used to report the specific test method used in the laboratory.
Fully-Specified Name
- Component
- Lab test method
- Property
- Type
- Time
- Pt
- System
- Specimen
- Scale
- Nom
- Method
- *
Basic Attributes
- Class
- MISC
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.58 (ADD)
- Order vs. Observation
- Observation
HL7® Attributes
HL7® Field ID- OBX-17
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 95405-7 | Assay related variables panel [PhenX] |
| 85905-8 | Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols |
| 85735-9 | Congenital rubella case report panel |
| 102116-1 | ESR1 gene mutation panel - Tissue by Molecular genetics method |
| 102117-9 | Gastrointestinal stromal tumor multigene mutation panel - Tissue by Molecular genetics method |
| 111577-3 | Hematologic malignancy gene fusion panel - Specimen by Molecular genetics method |
| 96629-1 | HLA-A and B and C (class I) typing panel - Blood or Tissue by Low resolution |
| 96628-3 | HLA-A and B and C (class I) typing panel - Blood or Tissue from Donor by Low resolution |
| 92254-2 | Microorganism identification and resistance pattern determination panel by Molecular genetics method |
| 102118-7 | Rhabdomyolysis and Metabolic myopathy multigene panel - Blood or Tissue by Molecular genetics method |
| 102119-5 | Skeletal muscle channelopathy multigene panel - Blood or Tissue by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Metoda laboratorního testu: |
| el-GR | Greek (Greece) | Μέθοδος εξέτασης εργαστηρίου: Synonyms: * MISC Nom Pt Type Δείγμα Μέθοδος Μέθοδος δοκιμής Μέθοδος εξέτασης εργαστηρίου |
| es-ES | Spanish (Spain) | Metodología de la prueba de laboratorio: |
| es-MX | Spanish (Mexico) | Método de prueba de laboratorio: |
| fr-FR | French (France) | Méthode du laboratoire: |
| it-IT | Italian (Italy) | Metodo test laboratorio: Synonyms: Metodo di test di laboratorio Miscellanea Punto nel tempo (episodio) |
| pl-PL | Polish (Poland) | Metoda badania laboratoryjnego: Synonyms: wynik kategorialny |
| zh-CN | Chinese (China) | 实验室检验方法: Synonyms: 供检查用的材料; |