Porcine epidemic diarrhea virus IgG Ab [Presence] in Serum by Immunofluorescence
This term is used to report the presence or absence of IgG antibodies against Porcine epidemic virus (PEDv) based on an immunofluorescence staining pattern. IgG antibodies to PEDv are typically be detected 7 to 14 days following exposure. Samples are compared to positive and negative controls. If cells fluoresce brilliant blue-green color against a background of non-infected cells, then the sample is considered positive; If cells do not fluoresce brilliantly but may show background non-specific fluorescence, then the sample is considered negative.; If cells fluoresce weakly and is not background fluorescence, then the sample is considered suspect. If high background fluorescence does not allow for an accurate determination to be made, then the sample is considered inconclusive.
Source: Regenstrief LOINC
LP182479-8 Porcine epidemic diarrhea virus
Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.
PEDv causes viral enteritis, which leads to the destruction of villus enterocytes in pigs of all ages. It is spread by the ingestion of feces from infected pigs, resulting in vomiting, watery diarrhea, dehydration, and high mortality, especially in nursery piglets. Disease caused by PEDv is clinically similar to that caused by Transmissible gastroenteritis coronavirus (TGEV) PMID: 26689811
At least two PEDv strains have been identified in the USA: the US PEDv prototype and S INDEL variant. The INDEL variant PEDv strain has insertions and deletions (INDELs) in the spike (S) gene. PMID: 25279722 The INDEL strain is related to milder clinical signs than prototype strains. PMID: 24750580 PMID: 26748596 The genomic differences in the S gene between the US PEDv prototype and INDEL variant may be responsible for the virulence differences. Potential targets when testing for PEDv RNA include the nucleocapsid protein (N) gene and the ~2500 bp fragment of the S-gene. Source: Regenstrief LOINC
- Porcine epidemic diarrhea virus Ab.IgG
- Short Name
- PEDv IgG Ser Ql IF
- Display Name
- Porcine epidemic diarrhea virus IgG IF Ql (S)
- Consumer Name Alpha Get Info
- Porcine Epidemic Diarrhea virus IgG antibody, Blood
Example Answer List: LL2431-6Source: Regenstrief LOINC
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
|InconclusiveCopyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value)||LA9663-1|
- First Released
- Version 2.61
- Last Updated
- Version 2.61
- Order vs. Observation
Language Variants Get Info
|es-ES||Spanish (Spain)||Virus de la diarrea epidémica porcina IgG:
|es-MX||Spanish (Mexico)||Virus de la diarrea epidémica porcina Ab.IgG:
|it-IT||Italian (Italy)||Virus della diarrea epidemica suina Ab.IgG:
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus PED
|nl-NL||Dutch (Netherlands)||'porcine' epizoötisch diarreevirus As.IgG:
|pl-PL||Polish (Poland)||Wirus epidemicznej biegunki świń Ab.IgG:
|ru-RU||Russian (Russian Federation)||Свиная эпидемическая диаррея вирус Ат.IgG:
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;
|tr-TR||Turkish (Turkey)||Porsin epidemik diyare virüsü Ab.IgG:
Synonyms: Ak Ak.IgG İmmünflorerans Mevcut
|zh-CN||Chinese (China)||猪流行性腹泻病毒 抗体.IgG:
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