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Term Description

This term is created for a test that involves amplification and sequencing of 3 open reading frames of VZV (ORF21, ORF22 and ORF50) to categorize strains into one of the 7 known clades of VZV.

Part Description

LP260859-6   Varicella zoster virus clade
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.http://jvi.asm.org/content/88/24/13936.full In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.https://grose.lab.uiowa.edu/vzv-genomes-and-evolution Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Varicella zoster virus clade:Type:Pt:XXX:Nom:Molgen
Long Common Name
Varicella zoster virus clade [Type] in Specimen by Molecular genetics method
Short Name
VZV clade Spec
Display Name
VZV clade Molgen Nom (Specimen)
Consumer Name Alpha Get Info
Varicella zoster virus clade, Specimen

Part Model Get Info

  • Component
    Varicella zoster virus clade
    LP260859-6
    • Analyte
      Varicella zoster virus clade
      LP260859-6
      • Component Numerator
        Varicella zoster virus clade
        LP260859-6
        • Component Numerator Core
          Varicella zoster virus clade
          LP260859-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Type
    LP6886-8
  • Time
    Pt
    LP6960-1
  • System
    XXX
    LP7735-6
    • System Core
      XXX
      LP7735-6
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Molgen
    LP6404-0

Example Answer List: LL4417-3

Source: Regenstrief LOINC
AnswerCodeScoreAnswer ID
Varicella-zoster virus clade 1LA27282-5
Varicella-zoster virus clade 2LA27283-3
Varicella-zoster virus clade 3LA27285-8
Varicella-zoster virus clade 4LA27286-6
Varicella-zoster virus clade 5LA27287-4
Varicella-zoster virus clade VILA27288-2
Varicella-zoster virus clade VIILA27289-0
Unable to typeLA27090-2
InconclusiveCopyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value)LA9663-1
Test not doneCopyright http://snomed.info/sct ID:373121007 Test not done (qualifier value)LA18373-3
VariableLA18409-5

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.69 (MIN)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG32750-8Varicella zoster virus

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus Varicella zoster klad:Typ:Časový bod:XXX:Nominální:Molekulární genetika
de-DEGerman (Germany)Varicella-Zoster-Virus-Klade:Typ:Zeitpunkt:XXX:Nominal:Molekulargenetisch
el-GRGreek (Greece)Κλάδος ιού της ανεμοβλογιάς-έρπητα ζωστήρα:Type:Pt:XXX:Nom:Μοριακή γενετική
Synonyms: MICRO Nom Pt Type XXX Ιός Ιός της ανεμοβλογιάς-έρπητα ζωστήρα Κλάδος ιού της ανεμοβλογιάς-έρπητα ζωστήρα Μοριακή γενετική
es-ESSpanish (Spain)Clados del virus de Varicela Zoster:Tipo:Punto temporal:XXX:Nom:Genética molecular
es-MXSpanish (Mexico)Clado del virus de la varicela zóster:Tipo:Punto temporal:XXX:Nominal:Genética molecular
fr-FRFrench (France)Varicelle zona virus clade:Type:Ponctuel:Milieux divers:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)Varicella zoster virus clade:Tipo:Pt:XXX:Nom:Molgen
Synonyms: Genetica molecolare Microbiologia Punto nel tempo (episodio) Virus della varicella zoster
nl-NLDutch (Netherlands)varicella-zostervirus clade:type:moment:XXX:nominaal:moleculair genetisch onderzoek
Synonyms: molgen Varicella zoster virus Varicella zoster virus clade
pl-PLPolish (Poland)Klad wirusa ospy wietrznej i półpaśca:typ:punkt w czasie:XXX:skala nominalna:genetyka molekularna
Synonyms: diagnostyka molekularna Klad VZV VZV wynik kategorialny
zh-CNChinese (China)水痘带状疱疹病毒进化枝:类型:时间点:XXX:名义型:分子遗传学类实验室方法
Synonyms: HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 型 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 水痘带状疱疹病毒（HHV-3、VZV、人类疱疹病毒 3 型、疱疹病毒 III 型、带状疱疹病毒、水痘-带状疱疹病毒）进化枝（分支、支、支系、分枝、分化体、种系分枝、演化支）

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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