Version 2.80

Part Description

LP182479-8   Porcine epidemic diarrhea virus
Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.
PEDv causes viral enteritis, which leads to the destruction of villus enterocytes in pigs of all ages. It is spread by the ingestion of feces from infected pigs, resulting in vomiting, watery diarrhea, dehydration, and high mortality, especially in nursery piglets. Disease caused by PEDv is clinically similar to that caused by Transmissible gastroenteritis coronavirus (TGEV) PMID: 26689811
At least two PEDv strains have been identified in the USA: the US PEDv prototype and S INDEL variant. The INDEL variant PEDv strain has insertions and deletions (INDELs) in the spike (S) gene. PMID: 25279722 The INDEL strain is related to milder clinical signs than prototype strains. PMID: 24750580 PMID: 26748596 The genomic differences in the S gene between the US PEDv prototype and INDEL variant may be responsible for the virulence differences. Potential targets when testing for PEDv RNA include the nucleocapsid protein (N) gene and the ~2500 bp fragment of the S-gene. Source: Regenstrief LOINC

Fully-Specified Name

Component
Porcine epidemic diarrhea virus Ab/Positive control
Property
RelRto
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Long Common Name
Porcine epidemic diarrhea virus Ab/Positive control in Serum by Immunoassay
Short Name
PEDv Ab/Pos cntrl Ser IA
Display Name
Porcine epidemic diarrhea virus Ab/Positive control IA (S) [Relative ratio]
Consumer Name Alpha Get Info
Porcine Epidemic Diarrhea virus/Positive Control, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ιός επιδημικής διάρροιας των χοίρων Αντίσωμα/Θετικός μάρτυρας:RelRto:Pt:Ορός:Qn:IA
Synonyms: RelRto Ιός Ιός επιδημικής διάρροιας των χοίρων Των χοίρων
es-ES Spanish (Spain) Virus de la diarrea epidémica porcina Anticuerpos/Control positivo:Ratio relativo:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Virus de la diarrea epidémica porcina Ab / Control positivo:Razón relativa:Punto temporal:Suero:Cuantitativo:Inmunoensayo
it-IT Italian (Italy) Virus della diarrea epidemica suina Ab/Controllo positivo:RelRto:Pt:Siero:Qn:IA
Synonyms: anticorpo Immunoassay Microbiologia Punto nel tempo (episodio) Rapporto Relativo Siero Virus PED
pl-PL Polish (Poland) Wirus epidemicznej biegunki świń Ab/kontrola dodatnia:współczynnik względny:punkt w czasie:surowica:ilościowy:metoda immunologiczna
tr-TR Turkish (Turkey) Porsin epidemik diyare virüsü Ab/Pozitif kontrol:GörOr:Zmlı:Ser:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 猪流行性腹泻病毒 抗体/阳性对照:相对比率:时间点:血清:定量型:免疫测定法
Synonyms: Ab;自身抗体 下痢;泄泻;下利;泻肚 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 来自于不同体系的两种分析物之比;相对比;相对比值 猪传染性腹泻病毒;PEDv 猪的 猪科 猪科的 结果阳性 试验阳性 试验阳性的 阳性对照（对照品、对照样品、对照样本、对照试样、对照标本、对照标准、参照、参照品） 阳性结果

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86695-4