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Part Description

LP262669-7   Clostridium perfringens iota toxin
Clostridium perfringens is a gram positive, anaerobic, rod-shaped bacterium. It is classified into five types designated A through E. Four toxins are produced by C. perfringens that have lethal, necrotic and cytotoxic capabilities. The four toxins are known as alpha-toxin (CPA), beta-toxin (CPB), epsilon-toxin (ETX) and iota-toxin (ITX). PMID: 22069542 When toxins produced by C. perfringens are mixed in different combination, sixteen toxins can be produced. Pathogenesis due to C. perfringens is due almost always to the production of one or more of its toxins. CPA is encoded by the cpa gene that is located on the chromosome and is produced by all strains of C. perfringens. CPA is an enzyme that breaks down phosphatidylcholine and sphingomyelin which damages membrane phospholipids and leads to the lysis of cells. CPA also cause hemolysis, activates the arachidonic cascade and inflammation cascade which induce vasoconstriction. There is no definitive evidence that CPA is involved with enteritis, abomasitis and/or enterotoxemia in cattle, horses, goats, and pigs. In humans, studies support that CPA is the main toxin believed to cause gas gangrene, a disease involving extensive local tissue damage and necrosis that leads to shock and death. Gas gangrene also occurs in domestic animals including sheep, cattle, goats, and horses. PMID: 24511335 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Clostridium perfringens iota toxin DNA:PrThr:Pt:Isolate:Ord:Probe.amp.tar
Long Common Name
Clostridium perfringens iota toxin DNA [Presence] in Isolate by NAA with probe detection
Short Name
C perfrin iota tox DNA Islt Ql NAA+probe
Display Name
C. perfringens iota toxin DNA NAA+probe Ql (Isol)
Consumer Name Alpha Get Info
Clostridium perfringens iota toxin

Part Model Get Info

  • Component
    Clostridium perfringens iota toxin DNA
    LP262516-0
    • Analyte
      Clostridium perfringens iota toxin DNA
      LP262516-0
      • Component Numerator
        Clostridium perfringens iota toxin DNA
        LP262516-0
        • Component Numerator Core
          Clostridium perfringens iota toxin
          LP262669-7
        • Component Numerator Core Suffix
          DNA
          LP32416-7
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Probe.amp.tar
    LP6464-4

Example Answer List: LL4623-6

AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6
SuspectedLA15291-0
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)LA15841-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Clostridium perfringens toxin iota DNA:Přítomnost nebo práh:Časový bod:Izolát:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
el-GRGreek (Greece)Τοξίνη Clostridium perfringens iota DNA:PrThr:Pt:Απομονωμένο στέλεχος:Ord:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: DNA MICRO Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Απομονωμένο στέλεχος Βακτήριο Clostridium perfringens Τοξίνη Clostridium perfringens iota
es-ESSpanish (Spain)Toxina iota Clostridium perfringens ADN:PrThr:Punto temporal:Aislado:Ord:Sonda con amplificación dirigida
es-MXSpanish (Mexico)ADN de la toxina de Clostridium perfringens iota:Presencia o umbral:Punto temporal:Aislado:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FRFrench (France)Clostridium perfringens toxine iota ADN:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
it-ITItalian (Italy)Clostridium perfringens, tossina iota DNA:PrThr:Pt:Isolato:Ord:Sonda.amp.tar
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NLDutch (Netherlands)Clostridium perfringens iota-toxine DNA:aanwezigheid:moment:isolaat:ordinaal:probe-detectie
Synonyms: probe.amp.tar
pl-PLPolish (Poland)Clostridium perfringens jota toksyna DNA:granica wykrywalności:punkt w czasie:izolat:uporządkowany:sonda.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Clostridium perfringens Jota Clostridium perfringens Kwas deoksyrybonukleinowy Toksyna jota Clostridium perfringens
zh-CNChinese (China)产气荚膜梭菌 iota 毒素 DNA:存在情况或阈值:时间点:分离株:序数型:探针法.基因扩增.靶向
Synonyms: 产气荚膜梭状芽胞杆菌;产气荚膜芽孢梭菌 产气荚膜梭菌（产气荚膜梭状芽胞杆菌、产气荚膜芽孢梭菌） iota 毒素 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分离物;分离菌;分离菌株;隔离种群 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87313-3