87409-9

Ustekinumab Ab [Units/volume] in Serum or Plasma by Immunoassay

Active

Term Description

This term was created for, but not limited in use to, the submitter's Theradiag Lisa-Tracker Ustekinumab and anti-Ustekinumab test kits.

Part Descriptions

LP250851-5 Ustekinumab
Ustekinumab (UST) is a human immunoglobulin G1κ (IgG1κ) that binds sub-unit p40 of interleukin-12 (IL-12) and interleukin-23 (IL-23). IL-12 and IL-23 are parts of the Th1 and Th17 inflammatory pathways, respectively, and are important in the development of psoriasis. Psoriasis has pathogenic similarities to psoriatic arthritis (PsA) which is an inflammatory disorder that is often unresponsive to tumor necrosis factor (TNF) inhibitor therapy. Also, many patients with PsA who initially respond well to TNF inhibitors eventually stop responding. UST is not a TNF inhibitor and offers patients with PsA an alternative treatment which has been proven to be effective and safe for short-term use. The safety for long-term use of UST still needs further study. PMID: 24101949 Source: Regenstrief LOINC

LP250854-9 Ustekinumab Ab
Antibodies to ustekinumab (ATU) have been detected in 6.5% of patients who were receiving ustekinumab for13 months. The presence of ATU is associated with reduced levels of ustekinumab and treatment failure. The number of patients who develop ATU is similar to the number of patients who failed therapy with adalimumab regardless of whether those patients were positive or negative for antibodies to adalimumab. PMID: 26566272 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Ustekinumab Ab:ACnc:Pt:Ser/Plas:Qn:IA
Long Common Name: Ustekinumab Ab [Units/volume] in Serum or Plasma by Immunoassay
Short Name: Ustekinumab Ab SerPl IA-aCnc
Display Name: Ustekinumab Ab IA Qn
Consumer Name Alpha Get Info: Ustekinumab antibody, Blood

Part Model Get Info

Component
Ustekinumab Ab
LP250854-9
- Analyte
  Ustekinumab Ab
  LP250854-9
  - Component Numerator
    Ustekinumab Ab
    LP250854-9
    - Component Numerator Core
      Ustekinumab
      LP250851-5
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.63
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 6769

Member of these Panels

LOINC	Long Common Name
101144-4	Ustekinumab and Ustekinumab Ab panel - Serum or Plasma

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Ustekinumab Ab:Arbitrární koncentrace:Časový bod:Sérum/plazma:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Ουστεκινουμάμπη Αντίσωμα:ACnc:Pt:Ορός/Πλάσμα:Qn:IA Synonyms: ACnc DRUG/TOX IA Pt Qn Αντίσωμα Ορός Ορός/Πλάσμα Ουστεκινουμάμπη Πλάσμα
es-ES	Spanish (Spain)	Ustekinumab Anticuerpos:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Ustekinumab Ab:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
fr-FR	French (France)	Ustekinumab Ac:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-IT	Italian (Italy)	Ustekinumab Ab:ACnc:Pt:Siero/Plasma:Qn:IA Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	ustekinumab As:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
zh-CN	Chinese (China)	优特克单抗抗体:任意型浓度:时间点:血清/血浆:定量型:免疫测定法 Synonyms: Ab;自身抗体任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度优特克单克隆抗体;优特克;Ustekinumab 单抗;优斯它单抗;优特克诺免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.