Version 2.80

Term Description

This term was created for, but not limited in use to, the submitter's Theradiag Lisa-Tracker Ustekinumab and anti-Ustekinumab test kits.

Part Descriptions

LP250851-5   Ustekinumab
Ustekinumab (UST) is a human immunoglobulin G1κ (IgG1κ) that binds sub-unit p40 of interleukin-12 (IL-12) and interleukin-23 (IL-23). IL-12 and IL-23 are parts of the Th1 and Th17 inflammatory pathways, respectively, and are important in the development of psoriasis. Psoriasis has pathogenic similarities to psoriatic arthritis (PsA) which is an inflammatory disorder that is often unresponsive to tumor necrosis factor (TNF) inhibitor therapy. Also, many patients with PsA who initially respond well to TNF inhibitors eventually stop responding. UST is not a TNF inhibitor and offers patients with PsA an alternative treatment which has been proven to be effective and safe for short-term use. The safety for long-term use of UST still needs further study. PMID: 24101949 Source: Regenstrief LOINC

LP250854-9   Ustekinumab Ab
Antibodies to ustekinumab (ATU) have been detected in 6.5% of patients who were receiving ustekinumab for13 months. The presence of ATU is associated with reduced levels of ustekinumab and treatment failure. The number of patients who develop ATU is similar to the number of patients who failed therapy with adalimumab regardless of whether those patients were positive or negative for antibodies to adalimumab. PMID: 26566272 Source: Regenstrief LOINC

Fully-Specified Name

Component
Ustekinumab Ab
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Long Common Name
Ustekinumab Ab [Units/volume] in Serum or Plasma by Immunoassay
Short Name
Ustekinumab Ab SerPl IA-aCnc
Display Name
Ustekinumab Ab IA Qn
Consumer Name Alpha Get Info
Ustekinumab antibody, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
6769

Member of these Panels

LOINC Long Common Name
101144-4 Ustekinumab and Ustekinumab Ab panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ουστεκινουμάμπη Αντίσωμα:ACnc:Pt:Ορός/Πλάσμα:Qn:IA
Synonyms: ACnc Ουστεκινουμάμπη
es-ES Spanish (Spain) Ustekinumab Anticuerpos:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Ustekinumab Ab:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
fr-FR French (France) Ustekinumab anticorps:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-IT Italian (Italy) Ustekinumab Ab:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) ustekinumab As:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
zh-CN Chinese (China) 优特克单抗 抗体:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ab;自身抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 优特克单克隆抗体;优特克;Ustekinumab 单抗;优斯它单抗;优特克诺 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87409-9