Version 2.72

882-1ABO and Rh group [Type] in BloodActive

Part Description

LP36683-8   ABO & Rh group
In 1900, Landsteiner observed that the red cells of some individuals were agglutinated by the serum of others and his detailed report a year later heralded the discovery of the first human blood groups. His limited experiments on laboratory colleagues demonstrated three distinct groups; his pupils Von Decastello and Sturli discovered a fourth group in 1902. It was 25 years before these groups were shown to be inherited as Mendelian characters by means of three allelomorphic genes A, B and O and were, in fact, entities of one blood group system. For most of medicine this was considered a meaningless curiosity, but for those involved with the early development of transfusions it was quickly noted that transfusion of blood only of the same group could mean the difference between a successful outcome or a fatality. While various nomenclatures have been used to describe these factors, it was internationally decided in the mid-1940's that the characteristics would be individually identified as A, B, AB and O and the blood group system know as ABO. Since that time there have been billions of tests preformed and almost as many publications describing various aspects and associations of this blood group systems or its allelic products. The genes controlling the ABO system are located on the long arm of chromosome 9 and encode for either an a (1-3) N-acetylgalactosaminyltransferase (for A) or a (1,3) galactosyltransferase (for B). These transferases incorporate immunodominant sugars (GalNAc for A; Gal for B) on to one of four different types of oligosaccharide chains (type 2 is predominant on red cells, type 1 is found in secretions, plasma and some tissue) carried on glycosphingolipid or glycoprotein molecules. The placement of the A and B antigens is dependent upon the existence of a substrate produced by the Hh blood group system (ISBT # 018). Some individuals have weakened or variant expression of A and/or B which can be attributed to inheritance of variant forms of transferases. Those individuals that have neither transferases, inheritors of two amorph genes, are group O. To date, 14 A alleles, 14 B alleles and 8 O alleles have been identified at the molecular level and more remain to be found. The ABO antigens, as stated above are not restricted to the red blood cell membrane but can be found in saliva and all body fluids except spinal fluid if the individual has inherited a secretor gene. The antigens are also found on most epithelial and endothelial cells. It also appears on lymphocytes and platelets as it is adsorbed from the plasma. Alterations of ABH expression have been found in various forms of cancer. Furthermore, antigens of the ABO system may play a role in resistance to bacteria or viruses. Source: Serum, Cells and Rare Fluid Exchange, ABO & Rh

Fully-Specified Name

ABO & Rh group

Additional Names

Short Name
ABO + Rh Bld
Display Name
ABO and Rh group (Bld)
Consumer Name Alpha
ABO and Rh group, Blood

Preferred Answer List LL2972-9

Source: Canada Health Infoway

Answer Code Score Answer ID
O Pos Copyright http://snomed.info/sct ID:278147001 Blood group O Rh(D) positive (finding) LA21321-7
O Neg Copyright http://snomed.info/sct ID:278148006 Blood group O Rh(D) negative (finding) LA21322-5
B Pos Copyright http://snomed.info/sct ID:278150003 Blood group B Rh(D) positive (finding) LA21327-4
B Neg Copyright http://snomed.info/sct ID:278153001 Blood group B Rh(D) negative (finding) LA21328-2
AB Pos Copyright http://snomed.info/sct ID:278151004 Blood group AB Rh(D) positive (finding) LA21323-3
AB Neg Copyright http://snomed.info/sct ID:278154007 Blood group AB Rh(D) negative (finding) LA21324-1
A Pos Copyright http://snomed.info/sct ID:278149003 Blood group A Rh(D) positive (finding) LA21325-8
A Neg Copyright http://snomed.info/sct ID:278152006 Blood group A Rh(D) negative (finding) LA21326-6

Basic Attributes

First Released
Version 1.0
Last Updated
Version 2.72
Order vs. Observation
Common US Lab Results Rank
Common SI Lab Results Rank

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
AB0 & Rh-bloedgroep:type:moment:bloed:nominaal:
et-EEEstonian (Estonia)
ABO ja Rh:Tüüp:Pt:B:Nom:
fr-CAFrench (Canada)
Groupe ABO & Rh:Type:Temps ponctuel:Sang:Nominal:
fr-FRFrench (France)
ABO et RHD groupage:Type:Ponctuel:Sang:Résultat nominal:
de-DEGerman (Germany)
AB0 & Rh-Blutgruppensysteme:Typ:Zeitpunkt:Blut:Nominal:
it-ITItalian (Italy)
ABO & Rh, gruppo:Tipo:Pt:Sangue:Nom:
ko-KRKorean (Korea, Republic of)
pt-BRPortuguese (Brazil)
Grupo ABO+Rh:Tipo:Pt:SgTotal:Nom:
ru-RURussian (Russian Federation)
ABO & Rh:Тип:ТчкВрм:Кр:Ном:
es-ARSpanish (Argentina)
grupo ABO + Rh:tipo:punto en el tiempo:sangre:Nominal:
es-MXSpanish (Mexico)
ABO y grupo Rh:Tipo:Punto temporal:Sangre:Nominal:
es-ESSpanish (Spain)
Grupo ABO y Rh:Tipo:Punto temporal:Sangre:Nom:
tr-TRTurkish (Turkey)
ABO ve Rh:Tip:Zmlı:Kan:Snf:

LOINC FHIR® API Example - CodeSystem Request Get Info