Version 2.76

Part Descriptions

LP16708-7   Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7   Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. PMID: 15914081 The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. PMID: 12186933 PMID: 1318940 Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis A virus genotype
Property
Type
Time
Pt
System
XXX
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
HAV Gentyp Spec NAA+probe
Display Name
HAV genotype NAA+probe (Specimen)
Consumer Name Alpha Get Info
Hepatitis A virus (HAV) genotype, Specimen

Example Answer List: LL4992-5

Source: Association of Public Health Laboratories
Answer Code Score Answer ID
Hepatitis A virus genotype I LA28917-5
Hepatitis A virus genotype II LA28918-3
Hepatitis A virus genotype III LA28919-1
Hepatitis A virus genotype IV LA28920-9
Hepatitis A virus genotype V LA28921-7
Hepatitis A virus subgenotype IA LA28923-3
Hepatitis A virus subgenotype IB LA28924-1
Hepatitis A virus subgenotype IIA LA28925-8
Hepatitis A virus subgenotype IIB LA28926-6
Hepatitis A virus subgenotype IIIA LA28927-4
Hepatitis A virus subgenotype IIIB LA28928-2
Not tested LA13538-6
Unable to complete sequencing LA28929-0

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.72
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32762-3 Hepatitis A virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-A-Virus Genotyp:Typ:Zeitpunkt:XXX:Nominal:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepatovirus A; HAV
el-GR Greek (Greece) Ιός Ηπατίτιδας Α γονότυπος:Τύπος:Χρονική στιγμή:ΧΧΧ:Ονομαστική:Ανιχνευτής με ενίσχυση στόχου
Synonyms: HAV
es-ES Spanish (Spain) Virus de la Hepatitis A Genotipo:Tipo:Punto temporal:XXX:Nom:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Genotipo del virus de la hepatitis A:Tipo:Punto temporal:XXX:Nominal:Amplificación de ácidos nucleicos con detección de sonda
fr-BE French (Belgium) Virus de l'hépatite A Génotype:Type:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
Synonyms: Génotype HVA
fr-CA French (Canada) Virus de l'hépatite A , Génotype:Type:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
fr-FR French (France) Hépatite A virus génotype:Type:Ponctuel:Milieux divers:Résultat nominal:PCR amplification de cible
it-IT Italian (Italy) Epatite A, virus , genotipo:Tipo:Pt:XXX:Nom:Sonda.amp.tar
Synonyms: Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite A
nl-NL Dutch (Netherlands) Hepatitis A-virus genotype:type:moment:XXX:nominaal:probe-detectie
Synonyms: probe.amp.tar
ru-RU Russian (Russian Federation) Гепатита А вирус генотип:Тип:ТчкВрм:XXX:Ном:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Номинальный;Именной Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit A virüsü genotip:Tip:Zmlı:XXX:Snf:Prob.amf.hdf
Synonyms: Tür
zh-CN Chinese (China) 甲型肝炎病毒 基因型:类型:时间点:XXX:名义型:探针法.基因扩增.靶向
Synonyms: A 型 HAV;Hep A;甲型肝炎;甲肝;甲肝病毒;肝炎病毒 A 型 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 型 属模标本;遗传型 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 肝 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89373-5