90357-5
Chlamydia trachomatis and Neisseria gonorrhoeae rRNA panel - Nasopharynx by NAA with probe detection
Active
Part Description
LP115366-9 Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type.
Source: Regenstrief Help
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
---|---|---|---|---|
90357-5 | Chlamydia trachomatis and Neisseria gonorrhoeae rRNA panel - Nasopharynx by NAA with probe detection | |||
Indent57288-3 | Chlamydia trachomatis rRNA [Presence] in Nasopharynx by NAA with probe detection | |||
Indent57289-1 | Neisseria gonorrhoeae rRNA [Presence] in Nasopharynx by NAA with probe detection |
Fully-Specified Name
- Component
- Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel
- Property
- -
- Time
- Pt
- System
- Nph
- Scale
- -
- Method
- Probe.amp.tar
Additional Names
- Short Name
- C trach+GC pnl Nph NAA+probe
- Display Name
- C. trachomatis and N. gonorrhoeae rRNA panel NAA+probe (Nph)
- Consumer Name Alpha Get Info
- Chlamydia trachomatis and Neisseria gonorrhoeae panel, Nasopharynx
Basic Attributes
- Class
- PANEL.MICRO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.73
- Order vs. Observation
- Order
- Common Test Rank Get Info
- 8449
- Panel Type
- Panel
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Perfil de rRNA de Chlamydia trachomatis y Neisseria gonorrhoeae: |
es-MX | Spanish (Mexico) | Panel de ARNr de Chlamydia trachomatis y Neisseria gonorrhoeae: |
fr-FR | French (France) | Chlamydia trachomatis et Neisseria gonorrhoeae ARNr panel: |
fr-CA | French (Canada) | Chlamydia trachomatis & Neisseria gonorrhoeae, ARNr: |
it-IT | Italian (Italy) | Chlamydia trachomatis & Neisseria gonorrhoeae, panel rRNA: Synonyms: Chlamydia trachomatis e Neisseria gonorrhoeae Microbiologia Panel rRNA Chlamydia trachomatis e Neisseria gonor Punto nel tempo (episodio) Rinofaringe Set di prescrizione microbiologia Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
nl-NL | Dutch (Netherlands) | Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel: Synonyms: probe.amp.tar |
ru-RU | Russian (Russian Federation) | Chlamydia trachomatis & Neisseria gonorrhoeae рРНК панель: Synonyms: ДНК проба; |
zh-CN | Chinese (China) | 沙眼衣原体与淋病奈瑟菌 rRNA 组套: Synonyms: Gen-Probe rRNA 探针法.扩增.靶向 借助扩增的探针方法; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=90357-5 - Questionnaire definition
- https:
//fhir.loinc.org/Questionnaire/?url=http: //loinc.org/q/90357-5
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright