Version 2.80

Part Descriptions

LP269194-9   Cells.CD14-FLAER-
Paroxsmal nocturnal hemoglobinuria (PNH) is a condition that causes hemolytic anemia, bone marrow failure, and a proclivity to develop thrombosis. PNH occurs when the PIG-A gene of bone marrow stem cells undergoes mutation. Stems cells develop into erythrocytes (RBCs), white blood cells (WBCs), platelets, and mature cells that contain the PIG-A gene mutation, and as a result, lack a sufficient number of glycosylphosphatidylinositol-anchored protein (GPI-AP). The GPI-APs have various roles, some of which are to help to prevent RBC destruction, fight infection, and promote thrombosis.[https://www.hopkinsmedicine.org/kimmel_cancer_center/types_cancer/paroxysmal_nocturnal_hemoglobinuria_PNH.html] CD14, 16, 24, and 59 are GPI-linked proteins that are used as markers for the presence of GPI, as is fluorescent aerolysin (FLAER), which binds to GPI-APs. Patients with PNH lack sufficient GPIs and therefore have reduced expression of these cell markers and FLAER compared to patients without PNH. Patients with complete loss of CD59 are more likely to have hemolysis compared to patients with partial loss of CD59. Source: Regenstrief LOINC

LP17733-4   CD14
Found on Monocytes
Associated with some AML Source: Regenstrief LOINC

LP20018-5   CD33
Found on granulocyte and monocyte precursors, except stem cells;
Mature monocytes. Weak staining on mature granulocytes.
Associated with AML Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.CD14-FLAER-/Cells.CD33
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
CD14-FLAER- cells/Cells.CD33 (Monocytes) in Blood
Short Name
CD14-FLAER- cells/CD33 NFr Bld
Display Name
CD14-FLAER- cells/Cells.CD33 (Bld)
Consumer Name Alpha Get Info
CD14-FLAER- cells/Cells.CD33, Blood

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component; Release 2.72: LONG_COMMON_NAME: Added the cell type name to the display name to align with reference lab convention.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
90735-2 PNH GPI-Linked WBC and RBC Ag Panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κύτταρα.CD14-FLAER-/Κύτταρα.CD33:NFr:Pt:Αίμα:Qn:
Synonyms: CD14 CD33 NFr Κύτταρα Κύτταρα.CD14 Κύτταρα.CD14-FLAER- Κύτταρα.CD33
es-ES Spanish (Spain) Células CD14-FLAER-/Porcentaje CD33:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Celdas.CD14-FLAER- / 100 células.CD33:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-FR French (France) CD14-FLAER-/100 cellules CD33:Fraction de nombres:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Cellule.CD14-FLAER-/Cellule.CD33:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD14 Cellule CD14-FLAER- Cellule CD33 Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
pl-PL Polish (Poland) Komórki.CD14-FLAER-/100 komórek CD33:frakcja liczbowa:punkt w czasie:krew:ilościowy:
Synonyms: CD14 CD33 Komórki CD14 Komórki CD14-FLAER- Komórki CD14-FLAER-/100 komórek CD33
zh-CN Chinese (China) 细胞.CD14-FLAER-/细胞.CD33:计数型分数:时间点:全血:定量型:
Synonyms: Alexa Fluor 488-标记的气单胞菌溶素突变体 Alexa Fluor 488-标记的气溶毒素突变体 Alexa Fluor 488-标记的气溶素突变体 Alexa Fluor 488-标记的突变体气单胞菌溶素 Alexa Fluor 488-标记的突变体气溶毒素 Alexa Fluor 488-标记的突变体气溶素 Alexa Fluor 488-标记的突变型气单胞菌溶素 Alexa Fluor 488-标记的突变型气溶毒素 Alexa Fluor 488-标记的突变型气溶素 CD14细胞 CD33细胞 Fluor 488-标记的气单胞菌溶素突变体 Fluor 488-标记的气溶毒素突变体 Fluor 488-标记的气溶素突变体 Fluor 488-标记的突变体气单胞菌溶素 Fluor 488-标记的突变体气溶毒素 Fluor 488-标记的突变体气溶素 Fluor 488-标记的突变型气单胞菌溶素 Fluor 488-标记的突变型气溶毒素 Fluor 488-标记的突变型气溶素 Fluor 488-标记的突变型气溶素（Fluor 488-labeled mutant aerolysin，FLAER） gp67 LeuM3 Leu-M3 LeuM9 Leu-M9 LPS-R Mo2 Mo-2 My4 My-4 My9 My-9 p67 发现于单核细胞之上，与某些急性髓系白血病（AML）相关。 发现于除干细胞外的粒细胞和单核细胞的前体细胞、成熟单核细胞。成熟粒细胞之上的染色不强。与急性髓系白血病相关。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 脂多糖受体（LPS receptor，LPS-R） 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90736-0