Version 2.78

Part Descriptions

LP229975-0   Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions. PMCID: PMC4478035 The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. PMID: 23983888 The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. PMID: 24707504 Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC,

Fully-Specified Name

Component
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
AMPAR2 Ab CSF Ql CBA IFA
Display Name
AMPAR2 Ab Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info
AMPAR2 antibody, Spinal fluid

Example Answer List: LL2038-9

Source: Quest Diagnostics Inc.
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) LA11884-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.69
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Receptor 2 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
es-MX Spanish (Mexico) Receptor 2 Ab de alfa-amino-3-hidroxi-5-metil-4-isoxazolpropionato:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
fr-FR French (France) AMPA récepteur 2 anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT Italian (Italy) Recettore tipo 2 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Ab:PrThr:Pt:LCS:Ord:CBA IFA
Synonyms: AMPAR2 anticorpo Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
zh-CN Chinese (China) Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 2 抗体:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA
Synonyms: Ⅱ Ⅲ Ab;自身抗体 Alpha-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体 2;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 2;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 2;AMPAR2 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Hydroxy II III OH α 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 细胞结合分析免疫荧光法;CBA IFA 法 羟 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 间接荧光抗体 间接荧光抗体试验 阿尔法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90813-7