AMPAR2 Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay
LP229975-0 Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions.[PMCID: PMC4478035] The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast.[PMID: 23983888] The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia.[PMID: 24707504] Source: Regenstrief LOINC
LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC
- Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab
- CBA IFA
- Short Name
- AMPAR2 Ab CSF Ql CBA IFA
- Display Name
- AMPAR2 Ab Cell binding immunofluorescent assay Ql (CSF)
- Consumer Name Alpha
- AMPAR2 antibody, Spinal fluid
Example Answer List: LL2038-9Source: Quest Diagnostics Inc.
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
|IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)||LA11884-6|
- First Released
- Version 2.65
- Last Updated
- Version 2.69
- Order vs. Observation
|it-IT||Italian (Italy)||Recettore tipo 2 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Ab:
|fr-FR||French (France)||AMPA récepteur 2 anticorps:
|es-ES||Spanish (Spain)||Receptor 2 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato Anticuerpos:
|zh-CN||Chinese (China)||Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 2 抗体:
|es-MX||Spanish (Mexico)||Receptor 2 Ab de alfa-amino-3-hidroxi-5-metil-4-isoxazolpropionato:
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Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright