Contactin-associated protein 2 Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay
LP230270-3 Contactin-associated protein 2
Contactin-associated protein 2 (CASPR2) is present in the axons of the granule neurons of the cerebellum and the juxtaparanodal region of myelinated axons. Increased titers of CASPR2 antibodies were first discovered in patients with Morvan's syndrome. Symptoms of Morvan's syndrome include neuromyotonia, insomnia, autonomic dysfunction and neuropathic pain. Though CASPR2 antibodies have been found in 10% of patients with idiopathic cerebellar ataxia, no specific disease has been attributed to patients with the rare occurrence of positive antibodies for CASPR2 with cerebellar involvement.[PMID: 25846566] Source: Regenstrief LOINC
LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC
- Contactin-associated protein 2 Ab
- CBA IFA
- Short Name
- CASPR2 Ab CSF Ql CBA IFA
- Display Name
- Contactin-associated protein 2 Ab Cell binding immunofluorescent assay Ql (CSF)
- Consumer Name Alpha
- Contactin-associated protein 2 antibody, Spinal fluid
Example Answer List: LL2038-9Source: Quest Diagnostics Inc.
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
|IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)||LA11884-6|
- First Released
- Version 2.65
- Last Updated
- Version 2.69
- Order vs. Observation
Member of these Groups
|LOINC Group||Group Name|
|LG51429-5||Contactin-associated protein 2 Ab|
|it-IT||Italian (Italy)||Proteina 2 Contactin-associata Ab:
|fr-FR||French (France)||CASPR2 anticorps:
|es-ES||Spanish (Spain)||Proteína 2 asociada a contactina Anticuerpos:
|zh-CN||Chinese (China)||接触蛋白关联蛋白 2 抗体:
|es-MX||Spanish (Mexico)||Proteína 2 Ab asociada a contactina:
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Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright